Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

1045

Name

CDX2

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for CDX2
Links to the AnimalTFDB for CDX2

Regulation From TransFac database

Cdx-2(h) --> Lct(pg) (DNA binding).
Cdx-2(h) --> GUCY2C(h) (DNA binding).
Cdx-2(h) --> BCL2(h) (DNA binding).
Cdx-2(h) --> MUC2(h) (DNA binding; transactivation).
Cdx-2(h) --> Glc6Pase(r) (DNA binding).
Cdx-2(h) --> CLDN2(h) (DNA binding).
Cdx-2(h) --> RAGE(h) (DNA binding; transactivation).
Cdx-2(h) --> SI(h) (DNA binding).
Cdx-2(h) --> NOX1(h) (DNA binding).
Cdx-2(h) --> MUC4(h) (DNA binding).
Cdx-2(h) --> ACAT2(h) (DNA binding).
CDX2(h) --> Cdx-2(h) (expression).
beta-catenin(h) --> Cdx-2(h) (increase of abundance)
Cdx-2(h) --> UGT1A8(h) (DNA binding; transactivation).
Cdx-2(h) --> UGT1A10(h) (DNA binding; transactivation).
Cdx-2(h) --> Fabp1(r) (transactivation)
HNF-1alpha(m) + Cdx-2(h) <==> HNF-1alpha(m):Cdx-2(h) (binding)
HNF-1beta(m) + Cdx-2(h) <==> HNF-1beta(m):Cdx-2(h) (binding)
Cdx-2(h) --> SI(h) (DNA binding).
Cdx-2(h) --> NOX1(h) (DNA binding).
Cdx-2(h) --> p21Cip1(h) (increase of abundance)
Cdx-2(h) --> CDKN1A(h) (transactivation)
Cdx-2(h) --/ p16INK4a(h) (decrease of abundance)
Cdx-2(h) --/ p27Kip1(h) (decrease of abundance)
Cdx-2(h) --/ cyclinD1(h) (decrease of abundance)
Cdx-2(h) --/ cyclinA(h) (decrease of abundance)
Cdx-2(h) --/ pRb(h) (decrease of abundance)
Cdx-2(h) --/ pRb(h){p} (decrease of abundance)
Cdx-2(h) --> B3GALT5(h) (transactivation)
Cdx-2(h) --> MUC2(h) (transactivation)
CDX2(h) --> Cdx-2(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

60Phosphoserine (By similarity).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr13

Promoter: 27440817 - 27442817Agilent_014791

chr13

Promoter: 27440817 - 27442817GSE27584

chr13

Promoter: 27440817 - 27442817Agilent_014791_44K

chr13

Promoter: 27440817 - 27442817PMID:15706431

chr13

Promoter: 27440817 - 27442817PMID:15498792


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