| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1020 |
Name | CDK5 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for CDK5 |
| Links to the AnimalTFDB for CDK5 |
Regulation From TransFac database | Cdk5(h) --> ERK1(h){p} (increase of phosphorylation) | Cdk5(h) --> ERK2(h){p} (increase of phosphorylation) | Cdk5(h) --> AKT(h){p} (increase of phosphorylation) | Cdk5(h) --> Bcl-2(h) (increase of abundance) | Cdk5(h) --> proCaspase-3(h) (decrease of cleavage) | Cdk5(h) --> ICAD(h) (decrease of cleavage) | Cdk5(h) --> Cdk5(h) (expression). | N-Myc(m.s.) + ATP --Cdk5(h)--> N-Myc(m.s.){p} + ADP (phosphorylation) | Cdk5(h) --> Cdk5(h) (expression). | tyrosine 3-monooxygenase(r) + ATP --Cdk5(h)--> tyrosine 3-monooxygenase(r){pS31} + ADP (phosphorylation) | MEK1(rb) + ATP --Cdk5(h)--> MEK1(rb){p} + ADP (phosphorylation) | MEK1(h) + ATP --Cdk5(h)--> MEK1(h){p} + ADP (phosphorylation) | CRMP4(h) + ATP --Cdk5(h)--> CRMP4(h){pS522} + ADP (phosphorylation) | CRMP2(h) + ATP --Cdk5(h)--> CRMP2(h){pS522} + ADP (phosphorylation) | CRMP1(h) + ATP --Cdk5(h)--> CRMP1(h){pS522} + ADP (phosphorylation) | CRMP1(h) + ATP --Cdk5(h)--> CRMP1(h){pT509} + ADP (phosphorylation) | tppp(h) + 3 ATP --Cdk5(h)--> tppp(h){pT14}{pS18}{pS160} + 3 ADP (phosphorylation) |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 14 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 15 | Phosphotyrosine (by ABL1) (Bysimilarity). | Swiss-Prot 53.0 | 159 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 15 | Phosphotyrosine (Abl) | 14757045;9038181 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr7 |
Promoter: 150385429 - 150387429 | GSE27584 |
chr7 |
Promoter: 150385429 - 150387429 | Agilent_014791_44K |