Entrez Gene

Basic Information
Gene ID	9531
Name	BAG3

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.479_480delCC; p.Q161fs*8; 10:119670149-119670150	breast	carcinoma	Deletion - Frameshift
c.1124C>T; p.P375L; 10:119676678-119676678	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.806C>T; p.S269F; 10:119672553-119672553	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.268C>T; p.R90*; 10:119669938-119669938	skin	malignant_melanoma	Substitution - Nonsense
c.824G>T; p.S275I; 10:119672571-119672571	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.607C>T; p.R203W; 10:119672354-119672354	stomach	adenocarcinoma	Substitution - Missense
c.607C>T; p.R203W; 10:119672354-119672354	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1002T>G; p.P334P; 10:119676556-119676556	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1002T>G; p.P334P; 10:119676556-119676556	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1002T>G; p.P334P; 10:119676556-119676556	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1002T>G; p.P334P; 10:119676556-119676556	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.33G>A; p.Q11Q; 10:119651708-119651708	prostate	carcinoma	Substitution - coding silent
c.33G>A; p.Q11Q; 10:119651708-119651708	skin; trunk	malignant_melanoma; nodular	Substitution - coding silent
c.1601A>C; p.K534T; 10:119677155-119677155	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.508C>T; p.R170W; 10:119672255-119672255	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.880C>T; p.R294C; 10:119672627-119672627	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.881G>A; p.R294H; 10:119672628-119672628	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1481delT; p.E495fs*71; 10:119677035-119677035	liver	carcinoma; hepatocellular_carcinoma	Deletion - Frameshift
c.1157C>T; p.S386F; 10:119676711-119676711	skin	malignant_melanoma	Substitution - Missense
c.451T>C; p.C151R; 10:119670121-119670121	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1319A>G; p.D440G; 10:119676873-119676873	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.835T>C; p.S279P; 10:119672582-119672582	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.451T>C; p.C151R; 10:119670121-119670121	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.451T>C; p.C151R; 10:119670121-119670121	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.451T>C; p.C151R; 10:119670121-119670121	thyroid	other; neoplasm	Substitution - Missense
c.1363G>A; p.E455K; 10:119676917-119676917	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.624T>G; p.I208M; 10:119672371-119672371	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1419A>G; p.R473R; 10:119676973-119676973	kidney	other; neoplasm	Substitution - coding silent
c.636C>G; p.H212Q; 10:119672383-119672383	skin	malignant_melanoma	Substitution - Missense
c.1419A>G; p.R473R; 10:119676973-119676973	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.386C>T; p.A129V; 10:119670056-119670056	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.855G>A; p.T285T; 10:119672602-119672602	central_nervous_system; brain	glioma	Substitution - coding silent
c.855G>A; p.T285T; 10:119672602-119672602	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.781C>T; p.R261W; 10:119672528-119672528	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.781C>T; p.R261W; 10:119672528-119672528	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1160C>T; p.P387L; 10:119676714-119676714	pancreas	carcinoma	Substitution - Missense
c.726C>G; p.T242T; 10:119672473-119672473	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.726C>G; p.T242T; 10:119672473-119672473	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1615G>A; p.A539T; 10:119677169-119677169	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1615G>A; p.A539T; 10:119677169-119677169	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.573C>T; p.S191S; 10:119672320-119672320	breast	carcinoma	Substitution - coding silent
c.875C>T; p.P292L; 10:119672622-119672622	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1220C>T; p.P407L; 10:119676774-119676774	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.415C>T; p.R139W; 10:119670085-119670085	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1220C>T; p.P407L; 10:119676774-119676774	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1220C>T; p.P407L; 10:119676774-119676774	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1220C>T; p.P407L; 10:119676774-119676774	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1624G>A; p.A542T; 10:119677178-119677178	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.690_691GA>AG; p.T231A; 10:119672437-119672438	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1382A>T; p.E461V; 10:119676936-119676936	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1197C>T; p.S399S; 10:119676751-119676751	ovary	other; neoplasm	Substitution - coding silent
c.819A>T; p.A273A; 10:119672566-119672566	bone; femur	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.306C>T; p.G102G; 10:119669976-119669976	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.379G>A; p.A127T; 10:119670049-119670049	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.792C>T; p.S264S; 10:119672539-119672539	skin	malignant_melanoma	Substitution - coding silent
c.614A>G; p.Y205C; 10:119672361-119672361	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.434C>T; p.T145I; 10:119670104-119670104	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.645C>T; p.N215N; 10:119672392-119672392	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1305G>T; p.L435L; 10:119676859-119676859	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.626C>T; p.P209L; 10:119672373-119672373	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1530C>G; p.L510L; 10:119677084-119677084	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1413G>T; p.E471D; 10:119676967-119676967	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.772C>T; p.R258W; 10:119672519-119672519	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.853A>G; p.T285A; 10:119672600-119672600	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1056C>A; p.S352S; 10:119676610-119676610	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.827G>T; p.R276L; 10:119672574-119672574	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.298C>T; p.H100Y; 10:119669968-119669968	skin	malignant_melanoma	Substitution - Missense
c.625_626CC>TT; p.P209L; 10:119672372-119672373	skin; scalp	malignant_melanoma	Substitution - Missense
c.283C>T; p.P95S; 10:119669953-119669953	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.598C>T; p.Q200*; 10:119672345-119672345	liver	carcinoma	Substitution - Nonsense
c.1368G>A; p.E456E; 10:119676922-119676922	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1430G>A; p.R477H; 10:119676984-119676984	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1570A>G; p.I524V; 10:119677124-119677124	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1570A>G; p.I524V; 10:119677124-119677124	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.854C>T; p.T285M; 10:119672601-119672601	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.289C>T; p.P97S; 10:119669959-119669959	breast	carcinoma	Substitution - Missense
c.378G>A; p.A126A; 10:119670048-119670048	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.470C>G; p.A157G; 10:119670140-119670140	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1228C>G; p.P410A; 10:119676782-119676782	pancreas	carcinoma	Substitution - Missense
c.794C>T; p.P265L; 10:119672541-119672541	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.44G>A; p.G15D; 10:119651719-119651719	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1033G>T; p.E345*; 10:119676587-119676587	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1085T>C; p.V362A; 10:119676639-119676639	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.578G>A; p.R193K; 10:119672325-119672325	skin	malignant_melanoma	Substitution - Missense
c.782G>A; p.R261Q; 10:119672529-119672529	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1444G>C; p.D482H; 10:119676998-119676998	kidney	carcinoma; renal_cell_carcinoma	Substitution - Missense
c.610G>T; p.G204W; 10:119672357-119672357	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.67delC; p.G25fs*186; 10:119651742-119651742	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.367C>T; p.R123*; 10:119670037-119670037	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1429C>T; p.R477C; 10:119676983-119676983	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1238C>T; p.A413V; 10:119676792-119676792	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.1429C>T; p.R477C; 10:119676983-119676983	stomach	adenocarcinoma	Substitution - Missense
c.1300G>A; p.G434R; 10:119676854-119676854	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.87G>T; p.K29N; 10:119651762-119651762	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3G>A; p.M1I; 10:119651678-119651678	urinary_tract; bladder	carcinoma	Substitution - Missense
c.888C>T; p.H296H; 10:119672635-119672635	pancreas	carcinoma	Substitution - coding silent
c.1078G>T; p.E360*; 10:119676632-119676632	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1416_1417delAC; p.R473fs*22; 10:119676970-119676971	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.1416_1417delAC; p.R473fs*22; 10:119676970-119676971	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.1416_1417delAC; p.R473fs*22; 10:119676970-119676971	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.1482delT; p.E495fs*71; 10:119677036-119677036	liver	carcinoma; hepatocellular_carcinoma	Deletion - Frameshift
c.1482delT; p.E495fs*71; 10:119677036-119677036	liver	carcinoma; hepatocellular_carcinoma	Deletion - Frameshift

The somatic mutations from COSMIC database