Entrez Gene

Basic Information
Gene ID	9475
Name	ROCK2

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.2488G>T; p.E830*; 2:11207787-11207787	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1016G>A; p.R339Q; 2:11222166-11222166	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3077C>T; p.T1026I; 2:11198513-11198513	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.569G>C; p.W190S; 2:11235856-11235856	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2551G>A; p.E851K; 2:11202120-11202120	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1016G>A; p.R339Q; 2:11222166-11222166	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2140C>T; p.R714*; 2:11211744-11211744	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.3923_3924insA; p.E1309fs*12; 2:11192476-11192477	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.3445C>T; p.P1149S; 2:11197183-11197183	skin	malignant_melanoma	Substitution - Missense
c.2823A>C; p.K941N; 2:11201044-11201044	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2823A>C; p.K941N; 2:11201044-11201044	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3268G>T; p.E1090*; 2:11197537-11197537	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.325-10A>G; p.?; 2:11249808-11249808	pancreas	carcinoma	Unknown
c.1370G>A; p.S457N; 2:11217132-11217132	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3727G>T; p.E1243*; 2:11192673-11192673	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2554C>T; p.R852C; 2:11202117-11202117	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma; medullomyoblastoma	Substitution - Missense
c.2554C>T; p.R852C; 2:11202117-11202117	central_nervous_system; brainstem	primitive_neuroectodermal_tumour-medulloblastoma; WNT_subtype	Substitution - Missense
c.2386A>G; p.I796V; 2:11207889-11207889	skin; extremity	malignant_melanoma	Substitution - Missense
c.2616C>A; p.F872L; 2:11202055-11202055	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2386A>G; p.I796V; 2:11207889-11207889	bone; femur	chondrosarcoma	Substitution - Missense
c.3676A>G; p.R1226G; 2:11193790-11193790	urinary_tract; bladder	carcinoma	Substitution - Missense
c.406delT; p.W138fs*31; 2:11249717-11249717	stomach	carcinoma; adenocarcinoma	Deletion - Frameshift
c.406delT; p.W138fs*31; 2:11249717-11249717	stomach	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4070C>T; p.P1357L; 2:11192241-11192241	skin	malignant_melanoma	Substitution - Missense
c.13C>T; p.P5S; 2:11344124-11344124	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2291T>G; p.L764*; 2:11208360-11208360	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.562G>A; p.E188K; 2:11235863-11235863	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.200A>C; p.N67T; 2:11287678-11287678	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.4027C>T; p.R1343W; 2:11192284-11192284	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.258G>C; p.Q86H; 2:11286605-11286605	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1142G>A; p.S381N; 2:11221315-11221315	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4014G>A; p.Q1338Q; 2:11192297-11192297	breast	carcinoma	Substitution - coding silent
c.3099+6T>C; p.?; 2:11198485-11198485	liver	carcinoma	Unknown
c.4029G>T; p.R1343R; 2:11192282-11192282	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.412_413insT; p.W138fs*12; 2:11249710-11249711	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.412_413insT; p.W138fs*12; 2:11249710-11249711	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.412_413insT; p.W138fs*12; 2:11249710-11249711	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.4029G>T; p.R1343R; 2:11192282-11192282	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.4029G>T; p.R1343R; 2:11192282-11192282	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.2627A>G; p.Y876C; 2:11201406-11201406	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2545C>T; p.R849*; 2:11207730-11207730	skin	malignant_melanoma	Substitution - Nonsense
c.1973G>A; p.G658D; 2:11214427-11214427	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.3040G>A; p.A1014T; 2:11198550-11198550	skin; extremity	malignant_melanoma	Substitution - Missense
c.575A>G; p.K192R; 2:11235850-11235850	liver	carcinoma	Substitution - Missense
c.575A>G; p.K192R; 2:11235850-11235850	liver	carcinoma	Substitution - Missense
c.27A>C; p.K9N; 2:11344110-11344110	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3888C>T; p.C1296C; 2:11192512-11192512	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1101G>A; p.T367T; 2:11221356-11221356	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.3776A>T; p.K1259M; 2:11192624-11192624	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1153G>A; p.D385N; 2:11221304-11221304	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.773C>T; p.S258L; 2:11227349-11227349	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1153G>A; p.D385N; 2:11221304-11221304	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2136G>T; p.K712N; 2:11211748-11211748	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2823A>G; p.K941K; 2:11201044-11201044	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1181T>C; p.V394A; 2:11221276-11221276	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4046C>A; p.P1349H; 2:11192265-11192265	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1426C>T; p.R476C; 2:11216193-11216193	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.199A>T; p.N67Y; 2:11287679-11287679	pancreas	carcinoma	Substitution - Missense
c.3314T>C; p.L1105P; 2:11197314-11197314	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1640A>T; p.N547I; 2:11215370-11215370	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2719G>A; p.E907K; 2:11201314-11201314	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3940C>T; p.P1314S; 2:11192460-11192460	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2936C>T; p.T979I; 2:11198749-11198749	skin	malignant_melanoma	Substitution - Missense
c.3329A>G; p.D1110G; 2:11197299-11197299	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4052delA; p.K1351fs*17; 2:11192259-11192259	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2928G>A; p.R976R; 2:11198757-11198757	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.392G>T; p.R131I; 2:11249731-11249731	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4101G>T; p.M1367I; 2:11192210-11192210	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.764A>T; p.D255V; 2:11227358-11227358	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.836C>T; p.S279F; 2:11227286-11227286	urinary_tract; bladder	carcinoma	Substitution - Missense
c.213C>G; p.F71L; 2:11287665-11287665	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1910G>T; p.G637V; 2:11214866-11214866	breast	carcinoma	Substitution - Missense
c.4091G>C; p.R1364T; 2:11192220-11192220	breast	carcinoma	Substitution - Missense
c.874A>T; p.T292S; 2:11224455-11224455	soft_tissue; striated_muscle	rhabdomyosarcoma; alveolar	Substitution - Missense
c.4022T>G; p.V1341G; 2:11192289-11192289	pancreas	carcinoma	Substitution - Missense
c.2529_2530insT; p.Q844fs*4; 2:11207745-11207746	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Insertion - Frameshift
c.2145A>G; p.L715L; 2:11211739-11211739	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3979C>G; p.L1327V; 2:11192332-11192332	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2050delA; p.S684fs*5; 2:11211834-11211834	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1970A>C; p.N657T; 2:11214430-11214430	breast	carcinoma	Substitution - Missense
c.3455G>A; p.R1152K; 2:11195019-11195019	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3328G>A; p.D1110N; 2:11197300-11197300	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3624C>T; p.V1208V; 2:11193842-11193842	skin	malignant_melanoma	Substitution - coding silent
c.12C>T; p.P4P; 2:11344125-11344125	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3580T>C; p.S1194P; 2:11194284-11194284	skin	malignant_melanoma	Substitution - Missense
c.3580T>C; p.S1194P; 2:11194284-11194284	skin	malignant_melanoma	Substitution - Missense
c.830G>T; p.W277L; 2:11227292-11227292	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.289G>A; p.V97I; 2:11286574-11286574	haematopoietic_and_lymphoid_tissue; abdomen	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.4082C>T; p.S1361L; 2:11192229-11192229	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1344A>G; p.K448K; 2:11217158-11217158	breast	carcinoma	Substitution - coding silent
c.868+1G>A; p.?; 2:11227253-11227253	urinary_tract; bladder	carcinoma	Unknown
c.2085A>C; p.K695N; 2:11211799-11211799	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3923delA; p.K1308fs*5; 2:11192477-11192477	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4078C>T; p.R1360*; 2:11192233-11192233	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.4078C>T; p.R1360*; 2:11192233-11192233	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2678T>G; p.L893R; 2:11201355-11201355	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2932C>A; p.L978I; 2:11198753-11198753	skin	malignant_melanoma	Substitution - Missense
c.3582C>A; p.S1194S; 2:11194282-11194282	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2932C>A; p.L978I; 2:11198753-11198753	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2389G>A; p.E797K; 2:11207886-11207886	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2488G>A; p.E830K; 2:11207787-11207787	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3582C>T; p.S1194S; 2:11194282-11194282	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3582C>T; p.S1194S; 2:11194282-11194282	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4010A>T; p.Q1337L; 2:11192301-11192301	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1909G>A; p.G637R; 2:11214867-11214867	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.3000A>C; p.Q1000H; 2:11198685-11198685	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4130G>A; p.R1377Q; 2:11192181-11192181	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1045_1061del17; p.R349fs*1; 2:11222121-11222137	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Deletion - Frameshift
c.509A>C; p.E170A; 2:11235916-11235916	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3975G>T; p.K1325N; 2:11192336-11192336	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.49G>T; p.A17S; 2:11344088-11344088	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.536A>G; p.N179S; 2:11235889-11235889	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.4139G>A; p.R1380Q; 2:11192172-11192172	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2565A>C; p.A855A; 2:11202106-11202106	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2390A>T; p.E797V; 2:11207885-11207885	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1518G>A; p.A506A; 2:11215589-11215589	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1518G>A; p.A506A; 2:11215589-11215589	prostate	carcinoma	Substitution - coding silent
c.3560G>A; p.S1187N; 2:11194304-11194304	breast	carcinoma	Substitution - Missense
c.930G>T; p.K310N; 2:11224399-11224399	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3609-1delG; p.?; 2:11193858-11193858	lung	carcinoma; adenocarcinoma	Unknown
c.3685C>T; p.Q1229*; 2:11193781-11193781	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1055C>T; p.P352L; 2:11222127-11222127	skin	malignant_melanoma	Substitution - Missense
c.4057C>A; p.P1353T; 2:11192254-11192254	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3011C>G; p.S1004*; 2:11198579-11198579	breast	carcinoma	Substitution - Nonsense
c.786G>A; p.L262L; 2:11227336-11227336	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.143A>G; p.D48G; 2:11287735-11287735	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.786G>A; p.L262L; 2:11227336-11227336	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.3469C>T; p.L1157F; 2:11195005-11195005	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1742T>A; p.L581*; 2:11215034-11215034	breast	carcinoma	Substitution - Nonsense
c.1586delT; p.L529fs*8; 2:11215521-11215521	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.980A>C; p.N327T; 2:11224349-11224349	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.980A>C; p.N327T; 2:11224349-11224349	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3782A>G; p.H1261R; 2:11192618-11192618	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.188G>A; p.R63K; 2:11287690-11287690	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3574G>T; p.E1192*; 2:11194290-11194290	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.643G>T; p.V215L; 2:11235782-11235782	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2971G>T; p.E991*; 2:11198714-11198714	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1203A>G; p.K401K; 2:11221254-11221254	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.769A>C; p.I257L; 2:11227353-11227353	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.3226A>C; p.K1076Q; 2:11197579-11197579	breast	carcinoma	Substitution - Missense
c.3424G>T; p.A1142S; 2:11197204-11197204	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2561A>T; p.D854V; 2:11202110-11202110	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.2561A>T; p.D854V; 2:11202110-11202110	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.2561A>T; p.D854V; 2:11202110-11202110	stomach	carcinoma	Substitution - Missense
c.2153A>C; p.K718T; 2:11211731-11211731	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3518_3519insA; p.Y1174fs*7; 2:11194955-11194956	skin	malignant_melanoma	Insertion - Frameshift
c.3518_3519insA; p.Y1174fs*7; 2:11194955-11194956	skin	malignant_melanoma	Insertion - Frameshift
c.514A>C; p.M172L; 2:11235911-11235911	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.345G>C; p.Q115H; 2:11249778-11249778	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2156delA; p.N719fs*15; 2:11211728-11211728	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2090T>C; p.I697T; 2:11211794-11211794	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2090T>C; p.I697T; 2:11211794-11211794	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3934A>G; p.I1312V; 2:11192466-11192466	liver	carcinoma	Substitution - Missense
c.3934A>G; p.I1312V; 2:11192466-11192466	liver	carcinoma	Substitution - Missense
c.2922T>C; p.T974T; 2:11198763-11198763	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4131G>A; p.R1377R; 2:11192180-11192180	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.4131G>A; p.R1377R; 2:11192180-11192180	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.4131G>A; p.R1377R; 2:11192180-11192180	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.319C>T; p.Q107*; 2:11286544-11286544	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2672C>A; p.T891N; 2:11201361-11201361	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1299C>A; p.S433S; 2:11218987-11218987	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3304C>T; p.R1102*; 2:11197324-11197324	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.765T>A; p.D255E; 2:11227357-11227357	skin	malignant_melanoma	Substitution - Missense
c.2297G>A; p.C766Y; 2:11208354-11208354	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3799C>T; p.L1267F; 2:11192601-11192601	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2203+2T>C; p.?; 2:11211679-11211679	stomach	carcinoma; adenocarcinoma	Unknown
c.3811C>T; p.P1271S; 2:11192589-11192589	skin	malignant_melanoma	Substitution - Missense
c.2388A>G; p.I796M; 2:11207887-11207887	urinary_tract; bladder	carcinoma	Substitution - Missense
c.362A>C; p.K121T; 2:11249761-11249761	skin	malignant_melanoma	Substitution - Missense
c.2119G>A; p.E707K; 2:11211765-11211765	urinary_tract; bladder	carcinoma	Substitution - Missense
c.74G>A; p.S25N; 2:11344063-11344063	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2119G>A; p.E707K; 2:11211765-11211765	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.982C>T; p.L328F; 2:11224347-11224347	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3220C>T; p.R1074C; 2:11197585-11197585	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2652A>G; p.K884K; 2:11201381-11201381	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.2125A>G; p.K709E; 2:11211759-11211759	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2335C>G; p.L779V; 2:11208316-11208316	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2669A>G; p.K890R; 2:11201364-11201364	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2898T>C; p.A966A; 2:11200969-11200969	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2898T>C; p.A966A; 2:11200969-11200969	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.205G>T; p.D69Y; 2:11287673-11287673	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3263T>G; p.L1088R; 2:11197542-11197542	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1936G>A; p.G646S; 2:11214840-11214840	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1715G>A; p.R572Q; 2:11215061-11215061	breast	carcinoma	Substitution - Missense
c.1736C>T; p.A579V; 2:11215040-11215040	skin	malignant_melanoma	Substitution - Missense
c.1441G>A; p.A481T; 2:11216178-11216178	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1099+9A>G; p.?; 2:11222074-11222074	liver	carcinoma	Unknown
c.762G>A; p.P254P; 2:11227360-11227360	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3372A>G; p.Q1124Q; 2:11197256-11197256	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2799A>T; p.E933D; 2:11201068-11201068	liver	carcinoma	Substitution - Missense
c.2799A>T; p.E933D; 2:11201068-11201068	liver	carcinoma	Substitution - Missense
c.3170G>T; p.R1057L; 2:11197635-11197635	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2670G>T; p.K890N; 2:11201363-11201363	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4136G>A; p.S1379N; 2:11192175-11192175	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.4136G>A; p.S1379N; 2:11192175-11192175	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3475T>C; p.L1159L; 2:11194999-11194999	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.3475T>C; p.L1159L; 2:11194999-11194999	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.412delT; p.W138fs*31; 2:11249711-11249711	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.412delT; p.W138fs*31; 2:11249711-11249711	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.412delT; p.W138fs*31; 2:11249711-11249711	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.412delT; p.W138fs*31; 2:11249711-11249711	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.412delT; p.W138fs*31; 2:11249711-11249711	stomach	adenocarcinoma	Deletion - Frameshift
c.412delT; p.W138fs*31; 2:11249711-11249711	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.412delT; p.W138fs*31; 2:11249711-11249711	stomach	adenocarcinoma	Deletion - Frameshift
c.1471C>G; p.R491G; 2:11215636-11215636	fallopian_tube	carcinoma; serous_carcinoma	Substitution - Missense
c.2066A>G; p.D689G; 2:11211818-11211818	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3637C>T; p.Q1213*; 2:11193829-11193829	kidney	other; neoplasm	Substitution - Nonsense
c.3898T>C; p.C1300R; 2:11192502-11192502	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1835C>T; p.A612V; 2:11214941-11214941	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.849C>T; p.F283F; 2:11227273-11227273	skin	malignant_melanoma	Substitution - coding silent
c.3300G>T; p.Q1100H; 2:11197328-11197328	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.849C>T; p.F283F; 2:11227273-11227273	skin	malignant_melanoma	Substitution - coding silent
c.2482A>C; p.K828Q; 2:11207793-11207793	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3260A>G; p.E1087G; 2:11197545-11197545	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2686G>T; p.E896*; 2:11201347-11201347	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1746G>A; p.R582R; 2:11215030-11215030	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1450C>G; p.L484V; 2:11216169-11216169	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1462-2A>C; p.?; 2:11215647-11215647	lung; right_upper_lobe	carcinoma; adenocarcinoma	Unknown
c.3734C>T; p.P1245L; 2:11192666-11192666	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3186G>T; p.E1062D; 2:11197619-11197619	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2529_2530insA; p.Q844fs*4; 2:11207745-11207746	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Insertion - Frameshift
c.128T>A; p.V43E; 2:11344009-11344009	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1007G>A; p.R336K; 2:11224322-11224322	skin	malignant_melanoma	Substitution - Missense
c.2094G>A; p.Q698Q; 2:11211790-11211790	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.987C>T; p.I329I; 2:11224342-11224342	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.342G>A; p.S114S; 2:11249781-11249781	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4028G>A; p.R1343Q; 2:11192283-11192283	thyroid	other; neoplasm	Substitution - Missense
c.2713C>A; p.Q905K; 2:11201320-11201320	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2847G>T; p.E949D; 2:11201020-11201020	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3184G>A; p.E1062K; 2:11197621-11197621	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1849G>C; p.E617Q; 2:11214927-11214927	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1665G>A; p.E555E; 2:11215345-11215345	ovary	other; neoplasm	Substitution - coding silent
c.113G>A; p.R38H; 2:11344024-11344024	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1619T>A; p.L540H; 2:11215391-11215391	central_nervous_system; brain	glioma	Substitution - Missense
c.318G>T; p.V106V; 2:11286545-11286545	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1988C>T; p.A663V; 2:11214412-11214412	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.405C>T; p.A135A; 2:11249718-11249718	skin	malignant_melanoma	Substitution - coding silent
c.3547C>T; p.L1183F; 2:11194317-11194317	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1869T>G; p.L623L; 2:11214907-11214907	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.3278C>T; p.A1093V; 2:11197527-11197527	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2599G>A; p.E867K; 2:11202072-11202072	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3547C>T; p.L1183F; 2:11194317-11194317	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.478C>T; p.Q160*; 2:11235947-11235947	skin	malignant_melanoma	Substitution - Nonsense

The somatic mutations from COSMIC database