Entrez Gene

Basic Information
Gene ID	9208
Name	LRRFIP1

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.1656C>T; p.N552N; 2:237763441-237763441	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.532C>A; p.L178I; 2:237753429-237753429	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.517G>T; p.D173Y; 2:237753414-237753414	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.287G>A; p.G96E; 2:237749200-237749200	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1699G>C; p.V567L; 2:237763484-237763484	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.68C>T; p.A23V; 2:237708545-237708545	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1700T>C; p.V567A; 2:237763485-237763485	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.773A>C; p.K258T; 2:237760161-237760161	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.120C>T; p.I40I; 2:237708597-237708597	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1885G>A; p.D629N; 2:237763670-237763670	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.203C>G; p.S68C; 2:237720776-237720776	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.1067C>G; p.S356C; 2:237762852-237762852	skin	malignant_melanoma	Substitution - Missense
c.166C>T; p.R56C; 2:237719535-237719535	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1698T>C; p.D566D; 2:237763483-237763483	breast	carcinoma	Substitution - coding silent
c.235C>T; p.R79C; 2:237720808-237720808	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.891T>C; p.T297T; 2:237762676-237762676	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.864G>T; p.V288V; 2:237762649-237762649	thyroid	other; neoplasm	Substitution - coding silent
c.197C>T; p.S66L; 2:237719566-237719566	skin	malignant_melanoma	Substitution - Missense
c.197C>T; p.S66L; 2:237719566-237719566	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.197C>T; p.S66L; 2:237719566-237719566	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1247C>T; p.S416L; 2:237763032-237763032	skin	malignant_melanoma	Substitution - Missense
c.1939C>G; p.L647V; 2:237763724-237763724	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.60G>A; p.Q20Q; 2:237692515-237692515	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.197C>T; p.S66L; 2:237719566-237719566	skin	malignant_melanoma	Substitution - Missense
c.285+2T>C; p.?; 2:237748401-237748401	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Unknown
c.2113delC; p.E706fs*35; 2:237763898-237763898	endometrium	carcinoma; endometrioid_carcinoma	Deletion - Frameshift
c.752A>G; p.Q251R; 2:237760140-237760140	skin	malignant_melanoma	Substitution - Missense
c.2204C>G; p.T735S; 2:237763989-237763989	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1670C>T; p.S557F; 2:237763455-237763455	skin	malignant_melanoma	Substitution - Missense
c.1670C>T; p.S557F; 2:237763455-237763455	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2247C>G; p.D749E; 2:237764032-237764032	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.726C>T; p.S242S; 2:237760114-237760114	pancreas	carcinoma	Substitution - coding silent
c.202T>C; p.S68P; 2:237720775-237720775	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.726C>T; p.S242S; 2:237760114-237760114	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1258G>A; p.G420R; 2:237763043-237763043	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1760T>C; p.V587A; 2:237763545-237763545	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.240A>G; p.G80G; 2:237720813-237720813	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.604G>A; p.A202T; 2:237756116-237756116	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.568G>A; p.E190K; 2:237753465-237753465	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1461G>T; p.E487D; 2:237763246-237763246	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.322C>A; p.L108M; 2:237749235-237749235	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.105G>A; p.A35A; 2:237708582-237708582	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2275C>G; p.H759D; 2:237764060-237764060	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.445A>T; p.K149*; 2:237753342-237753342	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.675+1G>T; p.?; 2:237756188-237756188	pancreas	carcinoma	Unknown
c.531G>A; p.E177E; 2:237753428-237753428	liver	carcinoma	Substitution - coding silent
c.770C>T; p.T257I; 2:237760158-237760158	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.531G>A; p.E177E; 2:237753428-237753428	liver	carcinoma	Substitution - coding silent
c.455T>C; p.V152A; 2:237753352-237753352	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2233C>A; p.L745I; 2:237764018-237764018	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.811A>G; p.T271A; 2:237760199-237760199	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.811A>G; p.T271A; 2:237760199-237760199	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1512C>T; p.N504N; 2:237763297-237763297	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.386C>T; p.T129I; 2:237749299-237749299	skin	malignant_melanoma	Substitution - Missense
c.1900C>T; p.Q634*; 2:237763685-237763685	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1900C>T; p.Q634*; 2:237763685-237763685	breast	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.113G>A; p.R38H; 2:237708590-237708590	liver	carcinoma	Substitution - Missense
c.611G>A; p.S204N; 2:237756123-237756123	bone; pelvis	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1181A>G; p.N394S; 2:237762966-237762966	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1758G>A; p.Q586Q; 2:237763543-237763543	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.416C>A; p.S139Y; 2:237753313-237753313	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.771A>G; p.T257T; 2:237760159-237760159	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2230A>G; p.S744G; 2:237764015-237764015	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.550G>A; p.E184K; 2:237753447-237753447	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2241C>T; p.N747N; 2:237764026-237764026	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1253C>T; p.P418L; 2:237763038-237763038	skin	malignant_melanoma	Substitution - Missense
c.271G>T; p.D91Y; 2:237748385-237748385	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1901A>G; p.Q634R; 2:237763686-237763686	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.271G>T; p.D91Y; 2:237748385-237748385	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.271G>T; p.D91Y; 2:237748385-237748385	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1687A>G; p.T563A; 2:237763472-237763472	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.173C>T; p.S58F; 2:237719542-237719542	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1977C>T; p.T659T; 2:237763762-237763762	skin	malignant_melanoma	Substitution - coding silent
c.1990G>C; p.G664R; 2:237763775-237763775	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1900C>A; p.Q634K; 2:237763685-237763685	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1900C>A; p.Q634K; 2:237763685-237763685	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.204T>C; p.S68S; 2:237720777-237720777	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1902A>G; p.Q634Q; 2:237763687-237763687	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1902A>G; p.Q634Q; 2:237763687-237763687	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2094C>T; p.D698D; 2:237763879-237763879	breast	carcinoma	Substitution - coding silent
c.900A>T; p.E300D; 2:237762685-237762685	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1817C>T; p.P606L; 2:237763602-237763602	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1054C>T; p.L352F; 2:237762839-237762839	skin	malignant_melanoma	Substitution - Missense
c.727G>A; p.D243N; 2:237760115-237760115	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.942G>T; p.E314D; 2:237762727-237762727	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1615G>T; p.D539Y; 2:237763400-237763400	liver	carcinoma	Substitution - Missense
c.1483C>T; p.P495S; 2:237763268-237763268	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1845T>C; p.S615S; 2:237763630-237763630	NS	NS	Substitution - coding silent
c.852C>A; p.I284I; 2:237762637-237762637	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.852C>T; p.I284I; 2:237762637-237762637	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.852C>A; p.I284I; 2:237762637-237762637	pancreas	carcinoma	Substitution - coding silent
c.852C>A; p.I284I; 2:237762637-237762637	breast	carcinoma	Substitution - coding silent
c.1461G>A; p.E487E; 2:237763246-237763246	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.852C>T; p.I284I; 2:237762637-237762637	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.900A>G; p.E300E; 2:237762685-237762685	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1422C>G; p.H474Q; 2:237763207-237763207	bone; femur	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1800C>T; p.N600N; 2:237763585-237763585	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2116G>A; p.E706K; 2:237763901-237763901	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.250-9C>T; p.?; 2:237748355-237748355	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1526C>T; p.T509I; 2:237763311-237763311	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1535G>A; p.S512N; 2:237763320-237763320	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.250-9C>T; p.?; 2:237748355-237748355	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.2095G>A; p.A699T; 2:237763880-237763880	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1285G>C; p.D429H; 2:237763070-237763070	skin	malignant_melanoma	Substitution - Missense
c.864delG; p.R291fs*17; 2:237762649-237762649	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.91C>T; p.R31W; 2:237708568-237708568	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.153+3A>G; p.?; 2:237708633-237708633	breast	carcinoma; ductal_carcinoma	Unknown
c.91C>T; p.R31W; 2:237708568-237708568	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.659G>C; p.R220T; 2:237756171-237756171	breast	carcinoma	Substitution - Missense
c.1426G>A; p.E476K; 2:237763211-237763211	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1638G>A; p.K546K; 2:237763423-237763423	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1321G>C; p.E441Q; 2:237763106-237763106	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1681G>A; p.V561I; 2:237763466-237763466	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.820A>G; p.R274G; 2:237762605-237762605	breast	carcinoma	Substitution - Missense
c.2063A>G; p.Q688R; 2:237763848-237763848	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1846G>A; p.E616K; 2:237763631-237763631	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2242G>A; p.D748N; 2:237764027-237764027	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense

The somatic mutations from COSMIC database