Entrez Gene

Basic Information
Gene ID	9021
Name	SOCS3

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.318C>T; p.S106S; 17:78358778-78358778	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.92A>G; p.Y31C; 17:78359004-78359004	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.211C>T; p.R71C; 17:78358885-78358885	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.429C>T; p.P143P; 17:78358667-78358667	skin	malignant_melanoma	Substitution - coding silent
c.246C>T; p.L82L; 17:78358850-78358850	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.221C>T; p.S74L; 17:78358875-78358875	skin	malignant_melanoma	Substitution - Missense
c.133G>T; p.G45C; 17:78358963-78358963	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.160G>A; p.G54S; 17:78358936-78358936	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.417A>T; p.P139P; 17:78358679-78358679	skin	malignant_melanoma	Substitution - coding silent
c.212G>A; p.R71H; 17:78358884-78358884	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; peripheral_T_cell_lymphoma_unspecified	Substitution - Missense
c.624C>T; p.T208T; 17:78358472-78358472	skin	malignant_melanoma	Substitution - coding silent
c.346C>T; p.R116C; 17:78358750-78358750	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.183T>G; p.S61R; 17:78358913-78358913	kidney	other; neoplasm	Substitution - Missense
c.280C>T; p.R94C; 17:78358816-78358816	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.280C>T; p.R94C; 17:78358816-78358816	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.507C>T; p.S169S; 17:78358589-78358589	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.589G>A; p.V197I; 17:78358507-78358507	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.294G>A; p.E98E; 17:78358802-78358802	skin	malignant_melanoma	Substitution - coding silent
c.328A>G; p.S110G; 17:78358768-78358768	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.634G>A; p.G212R; 17:78358462-78358462	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.214G>T; p.D72Y; 17:78358882-78358882	liver	carcinoma	Substitution - Missense
c.214G>T; p.D72Y; 17:78358882-78358882	liver	carcinoma	Substitution - Missense
c.214G>T; p.D72Y; 17:78358882-78358882	liver	carcinoma	Substitution - Missense
c.624C>A; p.T208T; 17:78358472-78358472	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.299delG; p.G100fs*79; 17:78358797-78358797	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.299delG; p.G100fs*79; 17:78358797-78358797	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.299delG; p.G100fs*79; 17:78358797-78358797	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.632C>T; p.P211L; 17:78358464-78358464	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.414G>A; p.S138S; 17:78358682-78358682	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.131G>A; p.S44N; 17:78358965-78358965	skin; arm	malignant_melanoma	Substitution - Missense
c.281G>T; p.R94L; 17:78358815-78358815	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.347G>A; p.R116H; 17:78358749-78358749	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.218G>A; p.S73N; 17:78358878-78358878	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.654G>A; p.L218L; 17:78358442-78358442	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.582G>A; p.R194R; 17:78358514-78358514	pancreas	carcinoma; adenocarcinoma	Substitution - coding silent
c.447G>A; p.E149E; 17:78358649-78358649	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.281G>A; p.R94H; 17:78358815-78358815	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.469C>T; p.P157S; 17:78358627-78358627	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense

The somatic mutations from COSMIC database