Entrez Gene

Basic Information
Gene ID	8945
Name	BTRC

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.920A>T; p.Y307F; 10:101532374-101532374	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1764C>T; p.A588A; 10:101550806-101550806	skin	malignant_melanoma	Substitution - coding silent
c.1566G>T; p.G522G; 10:101536642-101536642	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.144C>T; p.L48L; 10:101430440-101430440	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.144C>T; p.L48L; 10:101430440-101430440	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.688G>A; p.E230K; 10:101526144-101526144	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1146T>G; p.H382Q; 10:101534709-101534709	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1146T>G; p.H382Q; 10:101534709-101534709	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.815A>G; p.Y272C; 10:101531308-101531308	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.815A>G; p.Y272C; 10:101531308-101531308	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.709T>A; p.S237T; 10:101526165-101526165	central_nervous_system; brainstem	glioma; astrocytoma_Grade_III	Substitution - Missense
c.366G>T; p.K122N; 10:101521680-101521680	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1762G>T; p.A588S; 10:101550804-101550804	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.778G>T; p.G260W; 10:101531271-101531271	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.139G>A; p.A47T; 10:101430435-101430435	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.139G>A; p.A47T; 10:101430435-101430435	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.139G>A; p.A47T; 10:101430435-101430435	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.556+7C>G; p.?; 10:101521877-101521877	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.710C>G; p.S237C; 10:101526166-101526166	central_nervous_system; brainstem	glioma; astrocytoma_Grade_III	Substitution - Missense
c.1780C>T; p.R594C; 10:101550822-101550822	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.777C>T; p.D259D; 10:101531270-101531270	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.833A>G; p.D278G; 10:101531326-101531326	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1207C>T; p.R403C; 10:101534770-101534770	skin	malignant_melanoma	Substitution - Missense
c.1584T>A; p.I528I; 10:101538299-101538299	skin	malignant_melanoma	Substitution - coding silent
c.1277G>A; p.R426Q; 10:101534840-101534840	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.710C>T; p.S237F; 10:101526166-101526166	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.421T>G; p.F141V; 10:101521735-101521735	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.84C>T; p.S28S; 10:101430380-101430380	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1678C>T; p.R560*; 10:101550720-101550720	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1678C>T; p.R560*; 10:101550720-101550720	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.779G>T; p.G260V; 10:101531272-101531272	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.641A>G; p.E214G; 10:101526097-101526097	liver	carcinoma	Substitution - Missense
c.1773_1774insC; p.R594fs*>13; 10:101550815-101550816	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1134G>A; p.T378T; 10:101534697-101534697	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1363A>G; p.T455A; 10:101535369-101535369	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1194C>T; p.T398T; 10:101534757-101534757	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1361G>A; p.S454N; 10:101535367-101535367	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.473C>T; p.S158F; 10:101521787-101521787	skin	malignant_melanoma	Substitution - Missense
c.372G>A; p.R124R; 10:101521686-101521686	central_nervous_system; brain	glioma	Substitution - coding silent
c.961C>T; p.R321*; 10:101532415-101532415	skin	malignant_melanoma	Substitution - Nonsense
c.113G>A; p.R38Q; 10:101430409-101430409	breast	carcinoma	Substitution - Missense
c.113G>A; p.R38Q; 10:101430409-101430409	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.397G>A; p.E133K; 10:101521711-101521711	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.555A>T; p.P185P; 10:101521869-101521869	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.147A>T; p.T49T; 10:101430443-101430443	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.303G>T; p.K101N; 10:101479436-101479436	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1313A>G; p.Y438C; 10:101534876-101534876	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.694A>G; p.M232V; 10:101526150-101526150	pancreas	carcinoma	Substitution - Missense
c.694A>G; p.M232V; 10:101526150-101526150	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1005C>T; p.C335C; 10:101532978-101532978	thyroid	carcinoma	Substitution - coding silent
c.189C>T; p.G63G; 10:101462013-101462013	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.559C>T; p.R187W; 10:101526015-101526015	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.196C>T; p.P66S; 10:101462020-101462020	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.196C>T; p.P66S; 10:101462020-101462020	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.824T>G; p.I275S; 10:101531317-101531317	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1776C>T; p.P592P; 10:101550818-101550818	skin	malignant_melanoma	Substitution - coding silent
c.425A>G; p.E142G; 10:101521739-101521739	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.740G>T; p.G247V; 10:101526196-101526196	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.654G>A; p.V218V; 10:101526110-101526110	liver	carcinoma	Substitution - coding silent
c.654G>A; p.V218V; 10:101526110-101526110	liver	carcinoma	Substitution - coding silent
c.1342A>G; p.I448V; 10:101534905-101534905	pancreas	carcinoma	Substitution - Missense
c.1342A>G; p.I448V; 10:101534905-101534905	pancreas	carcinoma	Substitution - Missense
c.1248T>G; p.I416M; 10:101534811-101534811	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.934G>A; p.D312N; 10:101532388-101532388	breast	carcinoma	Substitution - Missense
c.1379G>C; p.R460T; 10:101535385-101535385	breast	carcinoma	Substitution - Missense
c.1248T>G; p.I416M; 10:101534811-101534811	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1248T>G; p.I416M; 10:101534811-101534811	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1784C>T; p.S595F; 10:101550826-101550826	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1619G>A; p.R540H; 10:101538334-101538334	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1537C>T; p.R513*; 10:101536613-101536613	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1537C>T; p.R513*; 10:101536613-101536613	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1541T>A; p.F514Y; 10:101536617-101536617	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1691A>T; p.D564V; 10:101550733-101550733	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.445C>T; p.Q149*; 10:101521759-101521759	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1634C>T; p.T545I; 10:101538349-101538349	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.108G>A; p.S36S; 10:101430404-101430404	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.102G>T; p.M34I; 10:101430398-101430398	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.442G>A; p.D148N; 10:101521756-101521756	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1790C>T; p.S597F; 10:101550832-101550832	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.962G>A; p.R321Q; 10:101532416-101532416	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1256G>A; p.R419Q; 10:101534819-101534819	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1256G>A; p.R419Q; 10:101534819-101534819	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1256G>A; p.R419Q; 10:101534819-101534819	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.896G>A; p.R299Q; 10:101532350-101532350	skin	malignant_melanoma	Substitution - Missense
c.112C>T; p.R38*; 10:101430408-101430408	breast	carcinoma	Substitution - Nonsense
c.580G>C; p.E194Q; 10:101526036-101526036	breast	carcinoma	Substitution - Missense
c.851C>A; p.S284Y; 10:101532305-101532305	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1092G>T; p.T364T; 10:101533065-101533065	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.810A>C; p.A270A; 10:101531303-101531303	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.710C>A; p.S237Y; 10:101526166-101526166	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.710C>A; p.S237Y; 10:101526166-101526166	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1315A>C; p.I439L; 10:101534878-101534878	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1694A>G; p.E565G; 10:101550736-101550736	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.349A>G; p.S117G; 10:101521663-101521663	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.863G>T; p.C288F; 10:101532317-101532317	liver	carcinoma	Substitution - Missense
c.1814G>A; p.R605K; 10:101550856-101550856	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.797C>A; p.S266Y; 10:101531290-101531290	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.901G>C; p.E301Q; 10:101532355-101532355	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1814G>A; p.R605K; 10:101550856-101550856	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.978G>A; p.K326K; 10:101532432-101532432	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1491A>G; p.A497A; 10:101536567-101536567	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.164C>A; p.S55*; 10:101461988-101461988	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.869G>A; p.R290K; 10:101532323-101532323	skin	malignant_melanoma	Substitution - Missense
c.1015C>T; p.L339F; 10:101532988-101532988	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.402G>T; p.K134N; 10:101521716-101521716	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1774delC; p.R594fs*>12; 10:101550816-101550816	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1774delC; p.R594fs*>12; 10:101550816-101550816	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1774delC; p.R594fs*>12; 10:101550816-101550816	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1774delC; p.R594fs*>12; 10:101550816-101550816	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1774delC; p.R594fs*>12; 10:101550816-101550816	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1793G>A; p.R598Q; 10:101550835-101550835	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1440G>C; p.V480V; 10:101535446-101535446	breast	carcinoma	Substitution - coding silent
c.1168C>T; p.R390C; 10:101534731-101534731	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.196C>A; p.P66T; 10:101462020-101462020	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1493G>A; p.C498Y; 10:101536569-101536569	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.947T>C; p.I316T; 10:101532401-101532401	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1374T>G; p.F458L; 10:101535380-101535380	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense

The somatic mutations from COSMIC database