Entrez Gene

Basic Information
Gene ID	8842
Name	PROM1

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.2125T>C; p.L709L; 4:15987668-15987668	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1185T>C; p.N395N; 4:16009065-16009065	liver	carcinoma	Substitution - coding silent
c.1185T>C; p.N395N; 4:16009065-16009065	liver	carcinoma	Substitution - coding silent
c.2314G>C; p.A772P; 4:15984322-15984322	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.2314G>C; p.A772P; 4:15984322-15984322	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.129C>T; p.T43T; 4:16075778-16075778	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.678G>A; p.A226A; 4:16024311-16024311	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2433delT; p.F811fs*3; 4:15980478-15980478	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1063G>A; p.G355S; 4:16016180-16016180	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.973C>T; p.Q325*; 4:16018352-16018352	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.619G>A; p.E207K; 4:16025203-16025203	skin	malignant_melanoma	Substitution - Missense
c.1220C>T; p.S407L; 4:16009030-16009030	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1243A>T; p.N415Y; 4:16009007-16009007	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2436G>A; p.A812A; 4:15980475-15980475	liver	carcinoma	Substitution - coding silent
c.2436G>A; p.A812A; 4:15980475-15980475	liver	carcinoma	Substitution - coding silent
c.265G>A; p.D89N; 4:16038957-16038957	skin	malignant_melanoma	Substitution - Missense
c.1078-4T>G; p.?; 4:16013342-16013342	kidney	other; neoplasm	Unknown
c.2536_2537insT; p.Y846fs*3; 4:15979440-15979441	breast	carcinoma	Insertion - Frameshift
c.396G>A; p.M132I; 4:16033417-16033417	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2484C>T; p.Y828Y; 4:15980427-15980427	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1245C>T; p.N415N; 4:16009005-16009005	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.288A>G; p.V96V; 4:16035750-16035750	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.1796A>G; p.E599G; 4:15992363-15992363	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1696_1697insA; p.N566fs*2; 4:15994057-15994058	pancreas	carcinoma; acinar_carcinoma	Insertion - Frameshift
c.1814T>C; p.L605P; 4:15992345-15992345	skin	malignant_melanoma	Substitution - Missense
c.1301+1G>T; p.?; 4:16008948-16008948	breast	carcinoma	Unknown
c.1322T>A; p.I441N; 4:16006670-16006670	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.567G>A; p.R189R; 4:16025255-16025255	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.56C>G; p.S19*; 4:16075851-16075851	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.984C>T; p.S328S; 4:16018341-16018341	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1195C>T; p.R399C; 4:16009055-16009055	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1468A>T; p.S490C; 4:16000606-16000606	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2017G>A; p.D673N; 4:15989791-15989791	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.857A>C; p.Q286P; 4:16018468-16018468	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.816C>A; p.N272K; 4:16018509-16018509	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2077A>T; p.S693C; 4:15987716-15987716	liver	carcinoma	Substitution - Missense
c.291C>A; p.I97I; 4:16035747-16035747	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1441G>A; p.V481I; 4:16006551-16006551	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1408A>T; p.T470S; 4:16006584-16006584	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1308G>C; p.L436L; 4:16006684-16006684	pancreas	carcinoma	Substitution - coding silent
c.1925C>G; p.P642R; 4:15991280-15991280	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.10G>A; p.V4I; 4:16075897-16075897	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2449_2450delAA; p.K817fs*13; 4:15980461-15980462	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.482C>T; p.S161F; 4:16033331-16033331	skin	malignant_melanoma	Substitution - Missense
c.779C>T; p.A260V; 4:16023331-16023331	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.806C>T; p.A269V; 4:16018519-16018519	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1498A>G; p.I500V; 4:16000576-16000576	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2279C>T; p.S760F; 4:15985761-15985761	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2281-6C>G; p.?; 4:15984361-15984361	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.1455-4C>G; p.?; 4:16000623-16000623	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.2430T>G; p.I810M; 4:15980481-15980481	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.2187C>G; p.N729K; 4:15985981-15985981	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - Missense
c.127A>C; p.T43P; 4:16075780-16075780	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1158G>A; p.L386L; 4:16009092-16009092	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2281A>G; p.I761V; 4:15984355-15984355	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.561C>A; p.I187I; 4:16025261-16025261	liver	carcinoma	Substitution - coding silent
c.561C>A; p.I187I; 4:16025261-16025261	liver	carcinoma	Substitution - coding silent
c.2043C>A; p.H681Q; 4:15989765-15989765	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1926C>A; p.P642P; 4:15991279-15991279	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2271C>T; p.I757I; 4:15985769-15985769	skin	malignant_melanoma	Substitution - coding silent
c.1926C>A; p.P642P; 4:15991279-15991279	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.2176T>A; p.F726I; 4:15985992-15985992	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2138T>A; p.V713E; 4:15986030-15986030	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1682+1G>A; p.?; 4:15998384-15998384	breast	carcinoma	Unknown
c.2188A>T; p.N730Y; 4:15985980-15985980	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.228G>A; p.L76L; 4:16038994-16038994	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.303+6G>A; p.?; 4:16035729-16035729	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.2212G>A; p.E738K; 4:15985828-15985828	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.228G>A; p.L76L; 4:16038994-16038994	breast	carcinoma	Substitution - coding silent
c.1234T>A; p.Y412N; 4:16009016-16009016	pancreas	carcinoma	Substitution - Missense
c.1234T>A; p.Y412N; 4:16009016-16009016	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.954C>T; p.S318S; 4:16018371-16018371	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1986C>T; p.P662P; 4:15989822-15989822	skin	malignant_melanoma	Substitution - coding silent
c.362T>C; p.I121T; 4:16033451-16033451	kidney	other; neoplasm	Substitution - Missense
c.1755C>T; p.L585L; 4:15993999-15993999	breast	carcinoma	Substitution - coding silent
c.387C>A; p.F129L; 4:16033426-16033426	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1002+1G>T; p.?; 4:16018322-16018322	lung	carcinoma; adenocarcinoma	Unknown
c.534G>T; p.V178V; 4:16025288-16025288	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1134C>T; p.V378V; 4:16013282-16013282	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.377T>G; p.V126G; 4:16033436-16033436	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1455-1G>T; p.?; 4:16000620-16000620	large_intestine; rectum	carcinoma; adenocarcinoma	Unknown
c.1871G>A; p.C624Y; 4:15992288-15992288	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.44G>A; p.G15E; 4:16075863-16075863	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2301G>A; p.S767S; 4:15984335-15984335	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1624C>T; p.L542F; 4:15998443-15998443	skin	malignant_melanoma	Substitution - Missense
c.2183_2184delCA; p.T728fs*9; 4:15985984-15985985	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1711G>A; p.G571S; 4:15994043-15994043	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.438A>C; p.R146R; 4:16033375-16033375	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1276A>G; p.T426A; 4:16008974-16008974	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1210G>A; p.D404N; 4:16009040-16009040	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1354_1355insT; p.Y452fs*13; 4:16006637-16006638	large_intestine; rectum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.605G>A; p.R202Q; 4:16025217-16025217	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.605G>A; p.R202Q; 4:16025217-16025217	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.605G>A; p.R202Q; 4:16025217-16025217	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.298C>G; p.L100V; 4:16035740-16035740	skin	malignant_melanoma	Substitution - Missense
c.1251A>C; p.E417D; 4:16008999-16008999	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.646T>G; p.L216V; 4:16024343-16024343	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.277C>A; p.P93T; 4:16035761-16035761	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.289A>C; p.I97L; 4:16035749-16035749	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.394A>G; p.M132V; 4:16033419-16033419	liver	carcinoma	Substitution - Missense
c.535_536GC>TT; p.A179L; 4:16025286-16025287	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.1078-1G>T; p.?; 4:16013339-16013339	lung	carcinoma; adenocarcinoma	Unknown
c.1245C>A; p.N415K; 4:16009005-16009005	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.651C>A; p.A217A; 4:16024338-16024338	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.259A>C; p.K87Q; 4:16038963-16038963	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1207C>A; p.Q403K; 4:16009043-16009043	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.774C>T; p.S258S; 4:16023336-16023336	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.843C>T; p.H281H; 4:16018482-16018482	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2272G>C; p.E758Q; 4:15985768-15985768	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.41G>A; p.C14Y; 4:16075866-16075866	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2009T>C; p.L670P; 4:15989799-15989799	central_nervous_system; brain	glioma	Substitution - Missense
c.1559C>G; p.T520R; 4:16000515-16000515	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1270T>G; p.L424V; 4:16008980-16008980	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2330C>A; p.T777N; 4:15984306-15984306	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2488G>C; p.D830H; 4:15980423-15980423	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2488G>C; p.D830H; 4:15980423-15980423	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.1012G>A; p.V338M; 4:16016231-16016231	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.676G>C; p.A226P; 4:16024313-16024313	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1837G>A; p.A613T; 4:15992322-15992322	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1146C>G; p.I382M; 4:16009104-16009104	breast	carcinoma	Substitution - Missense
c.2059C>G; p.P687A; 4:15989749-15989749	breast	carcinoma	Substitution - Missense
c.807G>A; p.A269A; 4:16018518-16018518	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.515G>A; p.G172D; 4:16025307-16025307	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1770T>C; p.H590H; 4:15992389-15992389	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.200A>C; p.Q67P; 4:16075707-16075707	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1680C>T; p.Y560Y; 4:15998387-15998387	breast	carcinoma	Substitution - coding silent
c.436C>T; p.R146*; 4:16033377-16033377	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1697delA; p.N566fs*29; 4:15994057-15994057	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1697delA; p.N566fs*29; 4:15994057-15994057	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1697_1698insA; p.N566fs*2; 4:15994056-15994057	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.815A>G; p.N272S; 4:16018510-16018510	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1697delA; p.N566fs*29; 4:15994057-15994057	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1697delA; p.N566fs*29; 4:15994057-15994057	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1697_1698insA; p.N566fs*2; 4:15994056-15994057	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1697delA; p.N566fs*29; 4:15994057-15994057	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1697delA; p.N566fs*29; 4:15994057-15994057	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1697delA; p.N566fs*29; 4:15994057-15994057	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1697delA; p.N566fs*29; 4:15994057-15994057	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1697delA; p.N566fs*29; 4:15994057-15994057	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1697delA; p.N566fs*29; 4:15994057-15994057	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1697delA; p.N566fs*29; 4:15994057-15994057	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1697delA; p.N566fs*29; 4:15994057-15994057	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1927G>A; p.A643T; 4:15991278-15991278	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2006C>T; p.S669F; 4:15989802-15989802	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2266T>C; p.W756R; 4:15985774-15985774	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1825C>A; p.L609M; 4:15992334-15992334	urinary_tract; bladder	carcinoma	Substitution - Missense
c.15C>T; p.L5L; 4:16075892-16075892	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.59G>T; p.G20V; 4:16075848-16075848	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.59G>T; p.G20V; 4:16075848-16075848	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1698T>C; p.N566N; 4:15994056-15994056	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.676G>A; p.A226T; 4:16024313-16024313	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1698T>C; p.N566N; 4:15994056-15994056	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1415G>A; p.R472Q; 4:16006577-16006577	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1415G>A; p.R472Q; 4:16006577-16006577	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1926C>T; p.P642P; 4:15991279-15991279	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1926C>T; p.P642P; 4:15991279-15991279	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1196G>A; p.R399H; 4:16009054-16009054	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.786G>A; p.A262A; 4:16018539-16018539	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1267A>C; p.N423H; 4:16008983-16008983	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.662C>A; p.T221N; 4:16024327-16024327	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1244A>G; p.N415S; 4:16009006-16009006	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2296G>T; p.A766S; 4:15984340-15984340	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.2174A>G; p.N725S; 4:15985994-15985994	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1244A>G; p.N415S; 4:16009006-16009006	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2296G>T; p.A766S; 4:15984340-15984340	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.2374-6T>C; p.?; 4:15980543-15980543	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown

The somatic mutations from COSMIC database