| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |||
|---|---|---|---|
Gene ID | 8841 | ||
Name | HDAC3 | ||
The somatic mutations from COSMIC database | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.1168A>G; p.T390A; 5:141625257-141625257 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.314C>T; p.S105L; 5:141630093-141630093 |
skin | malignant_melanoma | Substitution - Missense |
c.292C>T; p.P98S; 5:141630115-141630115 |
skin | malignant_melanoma | Substitution - Missense |
c.109C>A; p.L37M; 5:141636577-141636577 |
skin | malignant_melanoma | Substitution - Missense |
c.820C>T; p.R274*; 5:141627903-141627903 |
liver | carcinoma; hepatocellular_carcinoma | Substitution - Nonsense |
c.820C>T; p.R274*; 5:141627903-141627903 |
skin; trunk | malignant_melanoma; nodular | Substitution - Nonsense |
c.532C>T; p.Q178*; 5:141629251-141629251 |
skin | malignant_melanoma | Substitution - Nonsense |
c.926A>G; p.Y309C; 5:141626066-141626066 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.268G>A; p.V90I; 5:141634824-141634824 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.915C>G; p.R305R; 5:141626199-141626199 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.980-3A>T; p.?; 5:141625767-141625767 |
liver | carcinoma | Unknown |
c.980-3A>T; p.?; 5:141625767-141625767 |
liver | carcinoma; hepatocellular_carcinoma | Unknown |
c.980-3A>T; p.?; 5:141625767-141625767 |
liver | carcinoma | Unknown |
c.302T>C; p.F101S; 5:141630105-141630105 |
skin | malignant_melanoma | Substitution - Missense |
c.665C>T; p.P222L; 5:141628585-141628585 |
skin | malignant_melanoma | Substitution - Missense |
c.221G>A; p.S74N; 5:141634871-141634871 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.317G>A; p.R106H; 5:141630090-141630090 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.980-1G>T; p.?; 5:141625765-141625765 |
endometrium | carcinoma; endometrioid_carcinoma | Unknown |
c.489G>A; p.R163R; 5:141629294-141629294 |
liver | carcinoma; hepatocellular_carcinoma | Substitution - coding silent |
c.460A>G; p.I154V; 5:141629700-141629700 |
oesophagus; middle_third | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.1198_1199CC>TT; p.P400F; 5:141625226-141625227 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.1041G>T; p.E347D; 5:141625703-141625703 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.884G>A; p.G295D; 5:141626230-141626230 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.178C>T; p.R60C; 5:141634914-141634914 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.1012C>T; p.L338F; 5:141625732-141625732 |
breast | carcinoma | Substitution - Missense |
c.316C>T; p.R106C; 5:141630091-141630091 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.936G>A; p.S312S; 5:141626056-141626056 |
liver | carcinoma | Substitution - coding silent |
c.155A>G; p.Q52R; 5:141634937-141634937 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.750G>A; p.T250T; 5:141628129-141628129 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.179G>A; p.R60H; 5:141634913-141634913 |
pancreas | carcinoma | Substitution - Missense |
c.477-1G>T; p.?; 5:141629307-141629307 |
large_intestine; colon | carcinoma; adenocarcinoma | Unknown |
c.71T>C; p.M24T; 5:141636615-141636615 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.660C>T; p.N220N; 5:141628590-141628590 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.165A>G; p.Q55Q; 5:141634927-141634927 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.165A>G; p.Q55Q; 5:141634927-141634927 |
thyroid | other; neoplasm | Substitution - coding silent |
c.132G>T; p.K44N; 5:141636554-141636554 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.902G>T; p.R301L; 5:141626212-141626212 |
upper_aerodigestive_tract; pharynx | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.315G>A; p.S105S; 5:141630092-141630092 |
pancreas | carcinoma | Substitution - coding silent |
c.315G>A; p.S105S; 5:141630092-141630092 |
pancreas | carcinoma | Substitution - coding silent |
c.315G>A; p.S105S; 5:141630092-141630092 |
pancreas | carcinoma | Substitution - coding silent |
c.477-1G>A; p.?; 5:141629307-141629307 |
skin | malignant_melanoma | Unknown |
c.277G>A; p.D93N; 5:141634815-141634815 |
prostate | carcinoma | Substitution - Missense |
c.139-10C>A; p.?; 5:141634963-141634963 |
prostate | carcinoma; adenocarcinoma | Unknown |
c.420+1G>T; p.?; 5:141629859-141629859 |
ovary | carcinoma; serous_carcinoma | Unknown |
c.189C>T; p.S63S; 5:141634903-141634903 |
skin | malignant_melanoma | Substitution - coding silent |
c.571T>C; p.S191P; 5:141629212-141629212 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.273C>T; p.G91G; 5:141634819-141634819 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.334C>T; p.L112L; 5:141630073-141630073 |
lung | carcinoma; adenocarcinoma | Substitution - coding silent |
c.16G>A; p.A6T; 5:141636775-141636775 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.273C>T; p.G91G; 5:141634819-141634819 |
stomach | adenocarcinoma | Substitution - coding silent |
c.328G>A; p.A110T; 5:141630079-141630079 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.328G>A; p.A110T; 5:141630079-141630079 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.313T>C; p.S105P; 5:141630094-141630094 |
lung | carcinoma; small_cell_carcinoma | Substitution - Missense |
c.949G>T; p.E317*; 5:141626043-141626043 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Nonsense |
c.793C>T; p.R265*; 5:141627930-141627930 |
skin | malignant_melanoma | Substitution - Nonsense |
c.793C>T; p.R265*; 5:141627930-141627930 |
skin; trunk | malignant_melanoma; nodular | Substitution - Nonsense |
c.202G>A; p.D68N; 5:141634890-141634890 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.998C>T; p.A333V; 5:141625746-141625746 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.476+10C>A; p.?; 5:141629674-141629674 |
liver | carcinoma | Unknown |
c.476+10C>A; p.?; 5:141629674-141629674 |
liver | carcinoma | Unknown |
c.1118C>T; p.P373L; 5:141625307-141625307 |
skin | malignant_melanoma | Substitution - Missense |
c.1261G>T; p.D421Y; 5:141621494-141621494 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.510C>T; p.D170D; 5:141629273-141629273 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.643C>T; p.R215C; 5:141628607-141628607 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.837C>T; p.C279C; 5:141626277-141626277 |
large_intestine | carcinoma; adenocarcinoma | Substitution - coding silent |
c.837C>T; p.C279C; 5:141626277-141626277 |
large_intestine | carcinoma; adenocarcinoma | Substitution - coding silent |
c.526G>C; p.G176R; 5:141629257-141629257 |
ovary | carcinoma; serous_carcinoma | Substitution - Missense |
c.893A>T; p.Y298F; 5:141626221-141626221 |
liver | carcinoma | Substitution - Missense |
c.295G>A; p.G99R; 5:141630112-141630112 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.295G>A; p.G99R; 5:141630112-141630112 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.988G>A; p.E330K; 5:141625756-141625756 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.567G>A; p.T189T; 5:141629216-141629216 |
urinary_tract; bladder | carcinoma | Substitution - coding silent |
c.685G>T; p.D229Y; 5:141628565-141628565 |
thyroid | other; neoplasm | Substitution - Missense |
c.838G>A; p.V280I; 5:141626276-141626276 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.838G>A; p.V280I; 5:141626276-141626276 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.1057C>T; p.Q353*; 5:141625687-141625687 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Nonsense |
c.188_189CC>AT; p.S63Y; 5:141634903-141634904 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.1232A>G; p.N411S; 5:141621523-141621523 |
breast | carcinoma | Substitution - Missense |
c.332C>T; p.S111F; 5:141630075-141630075 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.1098G>T; p.L366L; 5:141625327-141625327 |
skin | malignant_melanoma | Substitution - coding silent |
c.443A>G; p.N148S; 5:141629717-141629717 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm; acute_myeloid_leukaemia | Substitution - Missense |
c.1098G>T; p.L366L; 5:141625327-141625327 |
skin | malignant_melanoma | Substitution - coding silent |
c.1137C>T; p.D379D; 5:141625288-141625288 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.272G>A; p.G91D; 5:141634820-141634820 |
skin; trunk | malignant_melanoma | Substitution - Missense |