Entrez Gene

Basic Information
Gene ID	8829
Name	NRP1

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.1332C>T; p.D444D; 10:33213668-33213668	skin	malignant_melanoma	Substitution - coding silent
c.1000C>T; p.R334C; 10:33226271-33226271	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.139T>A; p.S47T; 10:33330817-33330817	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1937A>G; p.Y646C; 10:33192406-33192406	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1789G>A; p.G597R; 10:33202966-33202966	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2222G>A; p.R741H; 10:33186329-33186329	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2199C>T; p.V733V; 10:33186352-33186352	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2347G>T; p.G783C; 10:33185712-33185712	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1577G>A; p.W526*; 10:33213423-33213423	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1569C>T; p.G523G; 10:33213431-33213431	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2106G>A; p.K702K; 10:33186445-33186445	skin	malignant_melanoma	Substitution - coding silent
c.1955T>G; p.F652C; 10:33192388-33192388	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.344C>T; p.S115L; 10:33270761-33270761	skin	malignant_melanoma	Substitution - Missense
c.1655G>A; p.R552Q; 10:33207676-33207676	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2624G>A; p.C875Y; 10:33180224-33180224	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.811G>T; p.E271*; 10:33256319-33256319	breast	carcinoma	Substitution - Nonsense
c.2506G>A; p.E836K; 10:33180342-33180342	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1080C>T; p.I360I; 10:33226191-33226191	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1897A>G; p.T633A; 10:33197677-33197677	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1996G>A; p.D666N; 10:33192347-33192347	breast	carcinoma	Substitution - Missense
c.1080C>T; p.I360I; 10:33226191-33226191	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.733A>C; p.M245L; 10:33256397-33256397	NS	NS	Substitution - Missense
c.1716C>A; p.G572G; 10:33207615-33207615	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1127A>G; p.N376S; 10:33226144-33226144	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1567G>C; p.G523R; 10:33213433-33213433	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1165G>T; p.D389Y; 10:33221836-33221836	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1967C>G; p.S656C; 10:33192376-33192376	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.878C>T; p.A293V; 10:33254131-33254131	breast	carcinoma	Substitution - Missense
c.382G>A; p.E128K; 10:33270723-33270723	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1698C>A; p.P566P; 10:33207633-33207633	prostate	carcinoma	Substitution - coding silent
c.382G>A; p.E128K; 10:33270723-33270723	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.517T>G; p.C173G; 10:33263787-33263787	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2355C>T; p.I785I; 10:33185704-33185704	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2355C>T; p.I785I; 10:33185704-33185704	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1031C>T; p.A344V; 10:33226240-33226240	skin	malignant_melanoma	Substitution - Missense
c.2120delG; p.R707fs*3; 10:33186431-33186431	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.1768G>C; p.A590P; 10:33202987-33202987	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.404C>T; p.S135F; 10:33270701-33270701	skin	malignant_melanoma	Substitution - Missense
c.1205G>A; p.R402Q; 10:33221796-33221796	skin	malignant_melanoma	Substitution - Missense
c.400T>C; p.F134L; 10:33270705-33270705	NS	NS	Substitution - Missense
c.1699G>A; p.E567K; 10:33207632-33207632	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.213C>G; p.F71L; 10:33330743-33330743	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2421A>C; p.E807D; 10:33185638-33185638	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.270C>T; p.F90F; 10:33270835-33270835	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.509G>A; p.S170N; 10:33263795-33263795	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.542A>G; p.K181R; 10:33263762-33263762	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1961G>A; p.W654*; 10:33192382-33192382	skin	malignant_melanoma	Substitution - Nonsense
c.2648G>C; p.C883S; 10:33180200-33180200	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1366A>G; p.N456D; 10:33213634-33213634	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1171G>A; p.V391M; 10:33221830-33221830	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; T_cell_large_granular_lymphocytic_leukaemia	Substitution - Missense
c.2509G>A; p.G837R; 10:33180339-33180339	skin	malignant_melanoma	Substitution - Missense
c.1885A>T; p.T629S; 10:33197689-33197689	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2094C>T; p.D698D; 10:33186457-33186457	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2094C>T; p.D698D; 10:33186457-33186457	pancreas	carcinoma	Substitution - coding silent
c.506A>G; p.N169S; 10:33263798-33263798	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1914C>T; p.T638T; 10:33197660-33197660	skin	malignant_melanoma	Substitution - coding silent
c.2454G>T; p.K818N; 10:33182726-33182726	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2238G>T; p.E746D; 10:33186313-33186313	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2763G>A; p.S921S; 10:33180085-33180085	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.1584G>A; p.M528I; 10:33213416-33213416	skin	malignant_melanoma	Substitution - Missense
c.349C>T; p.P117S; 10:33270756-33270756	pancreas	other; cystic_tumour	Substitution - Missense
c.609_610insG; p.M204fs*16; 10:33263694-33263695	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.2489C>T; p.T830M; 10:33180359-33180359	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.636A>C; p.E212D; 10:33263668-33263668	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.636A>C; p.E212D; 10:33263668-33263668	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.480C>T; p.S160S; 10:33263824-33263824	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.370G>T; p.V124F; 10:33270735-33270735	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma; medullomyoblastoma	Substitution - Missense
c.370G>T; p.V124F; 10:33270735-33270735	central_nervous_system; brainstem	primitive_neuroectodermal_tumour-medulloblastoma; WNT_subtype	Substitution - Missense
c.1591G>A; p.D531N; 10:33213409-33213409	breast	carcinoma	Substitution - Missense
c.1251G>A; p.M417I; 10:33221750-33221750	skin	malignant_melanoma	Substitution - Missense
c.1251G>A; p.M417I; 10:33221750-33221750	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.973T>A; p.W325R; 10:33254036-33254036	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2491C>T; p.P831S; 10:33180357-33180357	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1269T>C; p.G423G; 10:33221732-33221732	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1269T>C; p.G423G; 10:33221732-33221732	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1318G>C; p.G440R; 10:33213682-33213682	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.662G>T; p.G221V; 10:33256468-33256468	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.703C>T; p.R235*; 10:33256427-33256427	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2095G>A; p.E699K; 10:33186456-33186456	skin	malignant_melanoma	Substitution - Missense
c.703C>T; p.R235*; 10:33256427-33256427	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2095G>A; p.E699K; 10:33186456-33186456	skin; neck	malignant_melanoma	Substitution - Missense
c.2095G>A; p.E699K; 10:33186456-33186456	skin	malignant_melanoma	Substitution - Missense
c.1267G>A; p.G423S; 10:33221734-33221734	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1267G>A; p.G423S; 10:33221734-33221734	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1266C>T; p.Y422Y; 10:33221735-33221735	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.293A>T; p.H98L; 10:33270812-33270812	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1266C>T; p.Y422Y; 10:33221735-33221735	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1268G>A; p.G423D; 10:33221733-33221733	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2056C>T; p.H686Y; 10:33192287-33192287	skin	malignant_melanoma	Substitution - Missense
c.1298G>A; p.G433E; 10:33213702-33213702	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2350G>A; p.E784K; 10:33185709-33185709	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1610C>T; p.A537V; 10:33213390-33213390	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1610C>T; p.A537V; 10:33213390-33213390	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1161C>T; p.P387P; 10:33221840-33221840	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2350G>A; p.E784K; 10:33185709-33185709	skin	malignant_melanoma	Substitution - Missense
c.1161C>T; p.P387P; 10:33221840-33221840	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1610C>T; p.A537V; 10:33213390-33213390	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2350G>A; p.E784K; 10:33185709-33185709	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2350G>A; p.E784K; 10:33185709-33185709	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.77A>G; p.K26R; 10:33330879-33330879	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2233C>T; p.P745S; 10:33186318-33186318	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1631A>G; p.N544S; 10:33207700-33207700	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.815-1G>T; p.?; 10:33254195-33254195	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.483C>T; p.P161P; 10:33263821-33263821	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2053G>A; p.D685N; 10:33192290-33192290	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1247C>G; p.S416C; 10:33221754-33221754	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1799T>C; p.V600A; 10:33202956-33202956	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.355C>A; p.L119I; 10:33270750-33270750	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.355C>A; p.L119I; 10:33270750-33270750	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.593C>G; p.S198*; 10:33263711-33263711	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1864+6G>T; p.?; 10:33202885-33202885	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.850G>A; p.G284R; 10:33254159-33254159	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.489C>T; p.F163F; 10:33263815-33263815	skin	malignant_melanoma	Substitution - coding silent
c.696A>C; p.T232T; 10:33256434-33256434	skin	malignant_melanoma	Substitution - coding silent
c.1517G>A; p.R506Q; 10:33213483-33213483	skin	malignant_melanoma	Substitution - Missense
c.299G>A; p.R100K; 10:33270806-33270806	skin	malignant_melanoma	Substitution - Missense
c.271G>A; p.D91N; 10:33270834-33270834	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.735G>C; p.M245I; 10:33256395-33256395	lung	carcinoid-endocrine_tumour; atypical	Substitution - Missense
c.271G>A; p.D91N; 10:33270834-33270834	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2126T>G; p.V709G; 10:33186425-33186425	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2019G>A; p.W673*; 10:33192324-33192324	skin	malignant_melanoma	Substitution - Nonsense
c.2349C>T; p.G783G; 10:33185710-33185710	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1776G>A; p.P592P; 10:33202979-33202979	skin	malignant_melanoma	Substitution - coding silent
c.267C>T; p.V89V; 10:33270838-33270838	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1447G>A; p.E483K; 10:33213553-33213553	breast	carcinoma	Substitution - Missense
c.1527G>T; p.K509N; 10:33213473-33213473	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2751G>C; p.Q917H; 10:33180097-33180097	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2014A>G; p.K672E; 10:33192329-33192329	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1169T>C; p.V390A; 10:33221832-33221832	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1980C>A; p.F660L; 10:33192363-33192363	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2215A>C; p.K739Q; 10:33186336-33186336	skin	malignant_melanoma	Substitution - Missense
c.719C>T; p.S240L; 10:33256411-33256411	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.719C>T; p.S240L; 10:33256411-33256411	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2008C>T; p.Q670*; 10:33192335-33192335	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Nonsense
c.1213C>T; p.R405*; 10:33221788-33221788	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2523G>T; p.K841N; 10:33180325-33180325	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2672G>T; p.R891I; 10:33180176-33180176	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1030G>A; p.A344T; 10:33226241-33226241	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1718G>A; p.G573E; 10:33207613-33207613	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2114T>C; p.V705A; 10:33186437-33186437	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1388G>A; p.R463H; 10:33213612-33213612	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.624C>T; p.Y208Y; 10:33263680-33263680	skin	malignant_melanoma	Substitution - coding silent
c.1268G>C; p.G423A; 10:33221733-33221733	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1455C>T; p.L485L; 10:33213545-33213545	skin	malignant_melanoma	Substitution - coding silent
c.2197G>A; p.V733I; 10:33186354-33186354	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2197G>A; p.V733I; 10:33186354-33186354	thyroid	other; neoplasm	Substitution - Missense
c.2356G>T; p.G786*; 10:33185703-33185703	ovary	other; neoplasm	Substitution - Nonsense
c.537G>A; p.V179V; 10:33263767-33263767	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2356G>T; p.G786*; 10:33185703-33185703	ovary	other; neoplasm	Substitution - Nonsense
c.1688G>A; p.R563K; 10:33207643-33207643	skin	malignant_melanoma	Substitution - Missense
c.171G>A; p.L57L; 10:33330785-33330785	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.171G>A; p.L57L; 10:33330785-33330785	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.805G>T; p.V269F; 10:33256325-33256325	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.415G>A; p.E139K; 10:33270690-33270690	skin	malignant_melanoma	Substitution - Missense
c.1674C>T; p.S558S; 10:33207657-33207657	skin	malignant_melanoma	Substitution - coding silent
c.2004C>T; p.H668H; 10:33192339-33192339	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2005G>A; p.V669M; 10:33192338-33192338	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1756G>A; p.E586K; 10:33207575-33207575	breast	carcinoma	Substitution - Missense
c.1318G>A; p.G440R; 10:33213682-33213682	skin	malignant_melanoma	Substitution - Missense
c.722G>A; p.G241D; 10:33256408-33256408	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.241G>T; p.D81Y; 10:33330715-33330715	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2705A>G; p.E902G; 10:33180143-33180143	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.1815C>T; p.D605D; 10:33202940-33202940	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1196T>C; p.L399P; 10:33221805-33221805	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2588C>T; p.A863V; 10:33180260-33180260	breast	carcinoma	Substitution - Missense
c.2101C>T; p.Q701*; 10:33186450-33186450	breast	carcinoma	Substitution - Nonsense
c.162C>T; p.C54C; 10:33330794-33330794	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.668A>G; p.H223R; 10:33256462-33256462	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.606G>T; p.G202G; 10:33263698-33263698	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1018G>A; p.G340R; 10:33226253-33226253	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.322G>A; p.A108T; 10:33270783-33270783	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2363G>A; p.G788E; 10:33185696-33185696	skin; neck	malignant_melanoma	Substitution - Missense
c.1452G>A; p.W484*; 10:33213548-33213548	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1096G>A; p.G366R; 10:33226175-33226175	skin	malignant_melanoma	Substitution - Missense
c.537G>C; p.V179V; 10:33263767-33263767	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1482C>T; p.I494I; 10:33213518-33213518	skin	malignant_melanoma	Substitution - coding silent
c.2562A>G; p.L854L; 10:33180286-33180286	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.2595T>C; p.S865S; 10:33180253-33180253	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2595T>C; p.S865S; 10:33180253-33180253	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2595T>C; p.S865S; 10:33180253-33180253	thyroid	other; neoplasm	Substitution - coding silent
c.1566C>T; p.N522N; 10:33213434-33213434	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1806A>C; p.E602D; 10:33202949-33202949	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1179A>G; p.A393A; 10:33221822-33221822	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1262T>C; p.V421A; 10:33221739-33221739	thyroid	carcinoma	Substitution - Missense
c.1506T>G; p.G502G; 10:33213494-33213494	breast	carcinoma	Substitution - coding silent
c.2123delT; p.L708fs*2; 10:33186428-33186428	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.1325T>C; p.I442T; 10:33213675-33213675	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.962C>T; p.S321F; 10:33254047-33254047	skin	malignant_melanoma	Substitution - Missense
c.1165G>A; p.D389N; 10:33221836-33221836	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.829G>A; p.E277K; 10:33254180-33254180	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.1426G>A; p.A476T; 10:33213574-33213574	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2422G>A; p.D808N; 10:33185637-33185637	skin	malignant_melanoma	Substitution - Missense
c.428G>T; p.R143I; 10:33270677-33270677	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1483G>A; p.V495M; 10:33213517-33213517	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.605G>A; p.G202E; 10:33263699-33263699	skin; trunk	malignant_melanoma	Substitution - Missense
c.2245G>A; p.D749N; 10:33186306-33186306	skin	malignant_melanoma	Substitution - Missense
c.381C>T; p.Y127Y; 10:33270724-33270724	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1297G>T; p.G433*; 10:33213703-33213703	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2571C>T; p.I857I; 10:33180277-33180277	skin	malignant_melanoma	Substitution - coding silent
c.2220G>A; p.L740L; 10:33186331-33186331	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2594G>A; p.S865N; 10:33180254-33180254	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.348G>T; p.G116G; 10:33270757-33270757	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1572G>A; p.S524S; 10:33213428-33213428	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2129delG; p.S710fs*13; 10:33186422-33186422	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.543G>A; p.K181K; 10:33263761-33263761	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.2349C>A; p.G783G; 10:33185710-33185710	oesophagus	carcinoma	Substitution - coding silent
c.320T>A; p.I107K; 10:33270785-33270785	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2155G>A; p.A719T; 10:33186396-33186396	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.653C>G; p.P218R; 10:33263651-33263651	skin	malignant_melanoma	Substitution - Missense
c.1478A>C; p.K493T; 10:33213522-33213522	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense

The somatic mutations from COSMIC database