Entrez Gene

Basic Information
Gene ID	8792
Name	TNFRSF11A

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.220G>A; p.D74N; 18:62349874-62349874	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.405G>A; p.P135P; 18:62354512-62354512	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1000G>A; p.E334K; 18:62368917-62368917	oesophagus	carcinoma	Substitution - Missense
c.1331A>G; p.D444G; 18:62369248-62369248	liver	carcinoma	Substitution - Missense
c.400G>A; p.A134T; 18:62354507-62354507	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1314C>T; p.P438P; 18:62369231-62369231	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1331A>G; p.D444G; 18:62369248-62369248	liver	carcinoma	Substitution - Missense
c.1417G>A; p.A473T; 18:62369334-62369334	bone; scapula	chondrosarcoma	Substitution - Missense
c.1518G>T; p.R506S; 18:62369435-62369435	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.697G>A; p.V233I; 18:62361760-62361760	oesophagus	carcinoma	Substitution - Missense
c.811A>G; p.T271A; 18:62368728-62368728	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1641C>T; p.I547I; 18:62384824-62384824	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.907G>T; p.D303Y; 18:62368824-62368824	breast	carcinoma	Substitution - Missense
c.1514C>T; p.A505V; 18:62369431-62369431	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.482A>T; p.D161V; 18:62358302-62358302	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.482A>T; p.D161V; 18:62358302-62358302	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1727C>T; p.A576V; 18:62384910-62384910	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1057_1058CC>TT; p.P353F; 18:62368974-62368975	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.562G>A; p.E188K; 18:62359995-62359995	skin	malignant_melanoma	Substitution - Missense
c.101G>A; p.C34Y; 18:62348193-62348193	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1675G>T; p.A559S; 18:62384858-62384858	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.337G>T; p.A113S; 18:62354444-62354444	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.497C>T; p.T166M; 18:62358317-62358317	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.497C>T; p.T166M; 18:62358317-62358317	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1584C>T; p.N528N; 18:62384767-62384767	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1048A>C; p.M350L; 18:62368965-62368965	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.491C>T; p.S164F; 18:62358311-62358311	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.620C>T; p.P207L; 18:62361683-62361683	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.559A>G; p.T187A; 18:62359992-62359992	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1523G>T; p.G508V; 18:62369440-62369440	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1349G>A; p.R450Q; 18:62369266-62369266	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.426G>A; p.P142P; 18:62354533-62354533	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1071A>G; p.T357T; 18:62368988-62368988	breast	carcinoma	Substitution - coding silent
c.1287C>T; p.G429G; 18:62369204-62369204	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.372C>T; p.C124C; 18:62354479-62354479	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.741G>A; p.W247*; 18:62366718-62366718	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.662C>T; p.A221V; 18:62361725-62361725	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.1441G>A; p.E481K; 18:62369358-62369358	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.219G>A; p.P73P; 18:62349873-62349873	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.219G>A; p.P73P; 18:62349873-62349873	cervix	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1461G>A; p.T487T; 18:62369378-62369378	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.584G>A; p.S195N; 18:62360017-62360017	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.173C>A; p.S58Y; 18:62349827-62349827	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.399C>T; p.C133C; 18:62354506-62354506	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1701C>T; p.G567G; 18:62384884-62384884	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1193G>T; p.G398V; 18:62369110-62369110	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.879G>A; p.K293K; 18:62368796-62368796	skin	malignant_melanoma	Substitution - coding silent
c.223G>A; p.E75K; 18:62349877-62349877	skin	malignant_melanoma	Substitution - Missense
c.955G>A; p.A319T; 18:62368872-62368872	breast	carcinoma	Substitution - Missense
c.964G>A; p.E322K; 18:62368881-62368881	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.545T>C; p.V182A; 18:62359978-62359978	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.765C>T; p.G255G; 18:62366742-62366742	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1556C>T; p.S519F; 18:62369473-62369473	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.84G>A; p.L28L; 18:62348176-62348176	prostate	adenoma	Substitution - coding silent
c.983C>A; p.S328*; 18:62368900-62368900	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1143G>A; p.G381G; 18:62369060-62369060	skin	malignant_melanoma	Substitution - coding silent
c.1677G>A; p.A559A; 18:62384860-62384860	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.661G>A; p.A221T; 18:62361724-62361724	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1535G>A; p.G512E; 18:62369452-62369452	skin; head_neck	malignant_melanoma; superficial_spreading	Substitution - Missense
c.149G>A; p.C50Y; 18:62348241-62348241	skin	malignant_melanoma	Substitution - Missense
c.517A>G; p.T173A; 18:62358337-62358337	breast	carcinoma; ER-PR-positive_carcinoma	Substitution - Missense
c.522-5C>A; p.?; 18:62359950-62359950	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.756G>A; p.E252E; 18:62366733-62366733	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.132A>G; p.G44G; 18:62348224-62348224	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.214G>A; p.G72S; 18:62349868-62349868	breast	carcinoma	Substitution - Missense
c.1702C>T; p.R568C; 18:62384885-62384885	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.214G>T; p.G72C; 18:62349868-62349868	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.820G>A; p.A274T; 18:62368737-62368737	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1568G>T; p.G523V; 18:62384751-62384751	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1568G>T; p.G523V; 18:62384751-62384751	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.547G>C; p.E183Q; 18:62359980-62359980	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1293C>A; p.C431*; 18:62369210-62369210	skin; neck	malignant_melanoma	Substitution - Nonsense
c.1239G>T; p.W413C; 18:62369156-62369156	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1130C>T; p.P377L; 18:62369047-62369047	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1115C>A; p.P372H; 18:62369032-62369032	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1279G>A; p.D427N; 18:62369196-62369196	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.708G>A; p.R236R; 18:62361771-62361771	skin	malignant_melanoma	Substitution - coding silent
c.327C>T; p.P109P; 18:62354434-62354434	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1650C>T; p.Y550Y; 18:62384833-62384833	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1650C>T; p.Y550Y; 18:62384833-62384833	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1359T>C; p.P453P; 18:62369276-62369276	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.665C>T; p.S222F; 18:62361728-62361728	skin	malignant_melanoma	Substitution - Missense
c.783+1G>A; p.?; 18:62366761-62366761	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1346G>A; p.C449Y; 18:62369263-62369263	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.280A>G; p.T94A; 18:62349934-62349934	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1346G>A; p.C449Y; 18:62369263-62369263	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.1124C>T; p.S375F; 18:62369041-62369041	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1365G>T; p.E455D; 18:62369282-62369282	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.577G>T; p.V193F; 18:62360010-62360010	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1319C>T; p.P440L; 18:62369236-62369236	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.439A>G; p.K147E; 18:62358259-62358259	liver	carcinoma	Substitution - Missense
c.439A>G; p.K147E; 18:62358259-62358259	liver	carcinoma	Substitution - Missense
c.1246A>G; p.M416V; 18:62369163-62369163	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.721G>A; p.A241T; 18:62361784-62361784	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.301G>A; p.V101M; 18:62354408-62354408	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.424C>T; p.P142S; 18:62354531-62354531	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.233A>T; p.D78V; 18:62349887-62349887	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.421C>T; p.H141Y; 18:62354528-62354528	breast	carcinoma	Substitution - Missense
c.1295C>T; p.P432L; 18:62369212-62369212	skin; neck	malignant_melanoma	Substitution - Missense
c.421C>T; p.H141Y; 18:62354528-62354528	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1295C>T; p.P432L; 18:62369212-62369212	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1632C>T; p.G544G; 18:62384815-62384815	central_nervous_system; brain	glioma	Substitution - coding silent

The somatic mutations from COSMIC database