Entrez Gene

Basic Information
Gene ID	8743
Name	TNFSF10

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.426G>A; p.K142K; 3:172506912-172506912	skin	malignant_melanoma	Substitution - coding silent
c.693G>A; p.W231*; 3:172506645-172506645	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.693G>A; p.W231*; 3:172506645-172506645	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.693G>A; p.W231*; 3:172506645-172506645	skin	malignant_melanoma	Substitution - Nonsense
c.279G>C; p.L93F; 3:172511651-172511651	urinary_tract; bladder	carcinoma	Substitution - Missense
c.687T>C; p.S229S; 3:172506651-172506651	breast	carcinoma	Substitution - coding silent
c.592G>A; p.E198K; 3:172506746-172506746	skin; upper_arm	malignant_melanoma	Substitution - Missense
c.4G>T; p.A2S; 3:172523381-172523381	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.179A>G; p.E60G; 3:172514952-172514952	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.606C>T; p.N202N; 3:172506732-172506732	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.606C>T; p.N202N; 3:172506732-172506732	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.821T>A; p.F274Y; 3:172506517-172506517	skin	malignant_melanoma	Substitution - Missense
c.196G>A; p.D66N; 3:172514935-172514935	skin	malignant_melanoma	Substitution - Missense
c.33C>T; p.S11S; 3:172523352-172523352	breast	carcinoma	Substitution - coding silent
c.635A>C; p.K212T; 3:172506703-172506703	skin	malignant_melanoma	Substitution - Missense
c.208G>T; p.E70*; 3:172514923-172514923	liver	carcinoma	Substitution - Nonsense
c.208G>T; p.E70*; 3:172514923-172514923	liver	carcinoma	Substitution - Nonsense
c.356C>G; p.P119R; 3:172509279-172509279	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.525C>A; p.V175V; 3:172506813-172506813	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.572G>T; p.R191L; 3:172506766-172506766	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.336C>T; p.P112P; 3:172509299-172509299	skin	malignant_melanoma	Substitution - coding silent
c.724A>T; p.I242F; 3:172506614-172506614	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.538G>A; p.G180R; 3:172506800-172506800	breast	carcinoma	Substitution - Missense
c.831C>T; p.A277A; 3:172506507-172506507	skin	malignant_melanoma	Substitution - coding silent
c.834T>G; p.F278L; 3:172506504-172506504	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.77T>G; p.L26R; 3:172523308-172523308	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.223A>G; p.S75G; 3:172514908-172514908	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.828G>T; p.G276G; 3:172506510-172506510	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.572G>A; p.R191Q; 3:172506766-172506766	skin	malignant_melanoma	Substitution - Missense
c.418+2T>A; p.?; 3:172509215-172509215	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.418+2T>A; p.?; 3:172509215-172509215	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.650C>T; p.P217L; 3:172506688-172506688	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Substitution - Missense
c.723C>T; p.S241S; 3:172506615-172506615	skin	malignant_melanoma	Substitution - coding silent
c.314-3T>C; p.?; 3:172509324-172509324	liver	carcinoma	Unknown
c.36_37GG>AA; p.G13R; 3:172523348-172523349	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.754G>A; p.E252K; 3:172506584-172506584	skin; shoulder	malignant_melanoma	Substitution - Missense
c.754G>A; p.E252K; 3:172506584-172506584	skin	malignant_melanoma	Substitution - Missense
c.554A>G; p.Y185C; 3:172506784-172506784	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.445C>T; p.R149C; 3:172506893-172506893	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.634A>G; p.K212E; 3:172506704-172506704	skin	malignant_melanoma	Substitution - Missense
c.459C>T; p.S153S; 3:172506879-172506879	skin	malignant_melanoma	Substitution - coding silent
c.807C>T; p.D269D; 3:172506531-172506531	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.607G>A; p.D203N; 3:172506731-172506731	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.22G>T; p.G8W; 3:172523363-172523363	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.57C>T; p.I19I; 3:172523328-172523328	skin	malignant_melanoma	Substitution - coding silent
c.57C>T; p.I19I; 3:172523328-172523328	skin	malignant_melanoma	Substitution - coding silent
c.57C>T; p.I19I; 3:172523328-172523328	skin	malignant_melanoma	Substitution - coding silent
c.217A>G; p.M73V; 3:172514914-172514914	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.557C>T; p.S186F; 3:172506781-172506781	skin	malignant_melanoma	Substitution - Missense
c.291G>A; p.E97E; 3:172511639-172511639	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.181G>A; p.D61N; 3:172514950-172514950	breast	carcinoma	Substitution - Missense
c.649C>T; p.P217S; 3:172506689-172506689	skin	malignant_melanoma	Substitution - Missense
c.171C>A; p.F57L; 3:172514960-172514960	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.433A>T; p.K145*; 3:172506905-172506905	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.587T>A; p.I196K; 3:172506751-172506751	skin; upper_arm	malignant_melanoma	Substitution - Missense
c.412T>C; p.S138P; 3:172509223-172509223	urinary_tract; bladder	carcinoma	Substitution - Missense
c.375C>T; p.H125H; 3:172509260-172509260	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.26G>A; p.G9E; 3:172523359-172523359	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.32G>A; p.S11N; 3:172523353-172523353	skin	malignant_melanoma	Substitution - Missense
c.178G>T; p.E60*; 3:172514953-172514953	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.340G>A; p.V114M; 3:172509295-172509295	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.148T>A; p.S50T; 3:172514983-172514983	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.526A>G; p.I176V; 3:172506812-172506812	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.149C>A; p.S50Y; 3:172514982-172514982	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.657T>C; p.P219P; 3:172506681-172506681	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent

The somatic mutations from COSMIC database