Entrez Gene

Basic Information
Gene ID	8549
Name	LGR5

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.1221G>A; p.W407*; 12:71577937-71577937	skin	malignant_melanoma	Substitution - Nonsense
c.488C>T; p.S163F; 12:71553132-71553132	skin	malignant_melanoma	Substitution - Missense
c.2121C>T; p.G707G; 12:71584131-71584131	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2121C>T; p.G707G; 12:71584131-71584131	breast	carcinoma	Substitution - coding silent
c.1959C>T; p.F653F; 12:71583969-71583969	skin; neck	malignant_melanoma	Substitution - coding silent
c.2140C>A; p.P714T; 12:71584150-71584150	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2310G>T; p.L770L; 12:71584320-71584320	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2657C>A; p.P886Q; 12:71584667-71584667	lung	carcinoma; undifferentiated_carcinoma	Substitution - Missense
c.385G>A; p.V129I; 12:71535143-71535143	pancreas	carcinoma	Substitution - Missense
c.1131G>A; p.Q377Q; 12:71571574-71571574	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2421G>T; p.V807V; 12:71584431-71584431	skin	malignant_melanoma	Substitution - coding silent
c.2516A>G; p.Y839C; 12:71584526-71584526	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.236G>T; p.S79I; 12:71504637-71504637	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.425C>T; p.S142F; 12:71535183-71535183	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.997C>T; p.L333L; 12:71566699-71566699	skin	malignant_melanoma	Substitution - coding silent
c.2690A>G; p.H897R; 12:71584700-71584700	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2486A>G; p.E829G; 12:71584496-71584496	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.99C>A; p.G33G; 12:71440179-71440179	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1030C>T; p.P344S; 12:71566872-71566872	skin	malignant_melanoma	Substitution - Missense
c.1951_1952delTC; p.S651fs*22; 12:71583961-71583962	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2107G>A; p.G703S; 12:71584117-71584117	skin	malignant_melanoma	Substitution - Missense
c.1067T>A; p.V356E; 12:71566909-71566909	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1510G>A; p.D504N; 12:71580381-71580381	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.213-10T>C; p.?; 12:71504604-71504604	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.460delC; p.P155fs*10; 12:71553104-71553104	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.460delC; p.P155fs*10; 12:71553104-71553104	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.329T>G; p.F110C; 12:71524450-71524450	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.672C>T; p.S224S; 12:71556646-71556646	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1200C>T; p.L400L; 12:71572913-71572913	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2176A>T; p.M726L; 12:71584186-71584186	thyroid	other; neoplasm	Substitution - Missense
c.883T>C; p.F295L; 12:71566429-71566429	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.883T>C; p.F295L; 12:71566429-71566429	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.2487G>A; p.E829E; 12:71584497-71584497	thyroid	carcinoma; anaplastic_carcinoma	Substitution - coding silent
c.2052C>T; p.I684I; 12:71584062-71584062	skin	malignant_melanoma	Substitution - coding silent
c.2509C>T; p.Q837*; 12:71584519-71584519	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2618G>T; p.S873I; 12:71584628-71584628	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1470G>T; p.K490N; 12:71580341-71580341	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.216C>A; p.D72E; 12:71504617-71504617	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1754C>T; p.S585F; 12:71583764-71583764	skin	malignant_melanoma	Substitution - Missense
c.1754C>T; p.S585F; 12:71583764-71583764	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1754C>T; p.S585F; 12:71583764-71583764	skin	malignant_melanoma	Substitution - Missense
c.1754C>T; p.S585F; 12:71583764-71583764	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2375A>G; p.N792S; 12:71584385-71584385	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.294G>C; p.A98A; 12:71524415-71524415	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1407-1G>T; p.?; 12:71580277-71580277	lung	carcinoma; adenocarcinoma	Unknown
c.1244C>T; p.P415L; 12:71577960-71577960	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2292G>A; p.M764I; 12:71584302-71584302	skin; abdomen	malignant_melanoma	Substitution - Missense
c.230A>G; p.N77S; 12:71504631-71504631	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2469C>T; p.F823F; 12:71584479-71584479	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1202G>T; p.R401L; 12:71572915-71572915	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.230A>G; p.N77S; 12:71504631-71504631	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.646C>G; p.H216D; 12:71556620-71556620	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.19G>C; p.G7R; 12:71440099-71440099	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1240C>A; p.H414N; 12:71577956-71577956	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2696C>T; p.S899F; 12:71584706-71584706	skin; trunk	malignant_melanoma; nodular	Substitution - Missense
c.2438C>A; p.A813E; 12:71584448-71584448	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2280G>T; p.W760C; 12:71584290-71584290	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.435G>T; p.L145L; 12:71553079-71553079	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1950_1951delAT; p.S651fs*22; 12:71583960-71583961	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.652C>T; p.H218Y; 12:71556626-71556626	skin	malignant_melanoma	Substitution - Missense
c.258G>A; p.L86L; 12:71504659-71504659	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2260G>A; p.G754R; 12:71584270-71584270	skin	malignant_melanoma	Substitution - Missense
c.1321G>T; p.G441W; 12:71578844-71578844	skin	malignant_melanoma	Substitution - Missense
c.2655G>C; p.V885V; 12:71584665-71584665	breast	carcinoma	Substitution - coding silent
c.1533T>A; p.A511A; 12:71580404-71580404	kidney	other; neoplasm	Substitution - coding silent
c.2076C>T; p.A692A; 12:71584086-71584086	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2017G>A; p.E673K; 12:71584027-71584027	skin	malignant_melanoma	Substitution - Missense
c.2366C>T; p.S789F; 12:71584376-71584376	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1670G>A; p.G557D; 12:71583680-71583680	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.671C>T; p.S224F; 12:71556645-71556645	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1597C>T; p.L533L; 12:71582500-71582500	skin	malignant_melanoma	Substitution - coding silent
c.1791G>T; p.G597G; 12:71583801-71583801	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.276G>A; p.L92L; 12:71504677-71504677	skin	malignant_melanoma	Substitution - coding silent
c.1039G>C; p.V347L; 12:71566881-71566881	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1919T>C; p.I640T; 12:71583929-71583929	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2142T>C; p.P714P; 12:71584152-71584152	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2571C>T; p.V857V; 12:71584581-71584581	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.633C>G; p.S211R; 12:71553277-71553277	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1290G>A; p.S430S; 12:71578813-71578813	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2288C>G; p.S763C; 12:71584298-71584298	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1492G>T; p.G498C; 12:71580363-71580363	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1492G>T; p.G498C; 12:71580363-71580363	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1492G>T; p.G498C; 12:71580363-71580363	large_intestine; colon	carcinoma	Substitution - Missense
c.461C>T; p.P154L; 12:71553105-71553105	skin	malignant_melanoma	Substitution - Missense
c.1492G>T; p.G498C; 12:71580363-71580363	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1458G>A; p.E486E; 12:71580329-71580329	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1115T>C; p.V372A; 12:71571558-71571558	breast	carcinoma	Substitution - Missense
c.467G>T; p.S156I; 12:71553111-71553111	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.535G>A; p.V179I; 12:71553179-71553179	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1550A>G; p.Q517R; 12:71580421-71580421	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.942T>A; p.G314G; 12:71566644-71566644	liver	carcinoma	Substitution - coding silent
c.2129C>T; p.P710L; 12:71584139-71584139	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2201C>A; p.S734Y; 12:71584211-71584211	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2364C>G; p.S788S; 12:71584374-71584374	central_nervous_system; brain	glioma	Substitution - coding silent
c.284+1G>T; p.?; 12:71504686-71504686	breast	carcinoma	Unknown
c.2396A>C; p.E799A; 12:71584406-71584406	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2579A>G; p.Q860R; 12:71584589-71584589	breast	carcinoma	Substitution - Missense
c.534C>T; p.P178P; 12:71553178-71553178	skin	malignant_melanoma	Substitution - coding silent
c.1539G>A; p.M513I; 12:71580410-71580410	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.886G>T; p.V296F; 12:71566432-71566432	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.416G>T; p.S139I; 12:71535174-71535174	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1822G>A; p.V608I; 12:71583832-71583832	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.416G>T; p.S139I; 12:71535174-71535174	liver	carcinoma	Substitution - Missense
c.881A>G; p.Q294R; 12:71566427-71566427	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1645A>C; p.K549Q; 12:71583655-71583655	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1153G>A; p.E385K; 12:71572866-71572866	skin	malignant_melanoma	Substitution - Missense
c.1153G>A; p.E385K; 12:71572866-71572866	skin	malignant_melanoma	Substitution - Missense
c.2523G>A; p.W841*; 12:71584533-71584533	thyroid	carcinoma	Substitution - Nonsense
c.800A>G; p.N267S; 12:71561795-71561795	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.104C>T; p.P35L; 12:71440184-71440184	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2281G>T; p.D761Y; 12:71584291-71584291	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.2543G>A; p.S848N; 12:71584553-71584553	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1988G>C; p.G663A; 12:71583998-71583998	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1619A>T; p.Q540L; 12:71582522-71582522	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2361C>T; p.F787F; 12:71584371-71584371	skin	malignant_melanoma	Substitution - coding silent
c.211C>A; p.L71I; 12:71440291-71440291	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1022C>A; p.S341*; 12:71566864-71566864	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.337C>A; p.L113I; 12:71524458-71524458	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2680G>A; p.E894K; 12:71584690-71584690	skin	malignant_melanoma	Substitution - Missense
c.2515T>C; p.Y839H; 12:71584525-71584525	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1922_1923insT; p.L643fs*31; 12:71583932-71583933	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.2155G>A; p.E719K; 12:71584165-71584165	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2445C>G; p.L815L; 12:71584455-71584455	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.2202C>T; p.S734S; 12:71584212-71584212	skin; trunk	malignant_melanoma; nodular	Substitution - coding silent
c.2554A>G; p.I852V; 12:71584564-71584564	large_intestine; colon	adenoma	Substitution - Missense
c.2208C>T; p.C736C; 12:71584218-71584218	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1832C>T; p.A611V; 12:71583842-71583842	skin	malignant_melanoma	Substitution - Missense
c.1769C>T; p.S590F; 12:71583779-71583779	skin	malignant_melanoma	Substitution - Missense
c.1594G>A; p.D532N; 12:71582497-71582497	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.2122G>A; p.A708T; 12:71584132-71584132	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1751G>A; p.R584K; 12:71583761-71583761	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1205C>T; p.S402L; 12:71572918-71572918	skin; neck	malignant_melanoma	Substitution - Missense
c.95G>T; p.R32M; 12:71440175-71440175	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2265C>T; p.D755D; 12:71584275-71584275	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2663C>T; p.P888L; 12:71584673-71584673	central_nervous_system; brain	glioma	Substitution - Missense
c.2212C>T; p.L738F; 12:71584222-71584222	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1552+2T>C; p.?; 12:71580425-71580425	breast	carcinoma	Unknown
c.2052C>G; p.I684M; 12:71584062-71584062	skin; subungual	malignant_melanoma; acral_lentiginous	Substitution - Missense
c.2661A>C; p.S887S; 12:71584671-71584671	breast	carcinoma	Substitution - coding silent
c.2435C>T; p.P812L; 12:71584445-71584445	skin	malignant_melanoma	Substitution - Missense
c.1876C>T; p.R626*; 12:71583886-71583886	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1037C>T; p.T346I; 12:71566879-71566879	skin	malignant_melanoma	Substitution - Missense
c.2455C>T; p.L819F; 12:71584465-71584465	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1558C>T; p.R520C; 12:71582461-71582461	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2713C>T; p.P905S; 12:71584723-71584723	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1558C>T; p.R520C; 12:71582461-71582461	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1834G>A; p.V612M; 12:71583844-71583844	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.653A>G; p.H218R; 12:71556627-71556627	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.652C>A; p.H218N; 12:71556626-71556626	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.2514C>A; p.T838T; 12:71584524-71584524	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.267_268CC>TT; p.R90C; 12:71504668-71504669	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2514C>A; p.T838T; 12:71584524-71584524	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2514C>A; p.T838T; 12:71584524-71584524	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.2104G>A; p.G702S; 12:71584114-71584114	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2523G>T; p.W841C; 12:71584533-71584533	breast	carcinoma	Substitution - Missense
c.1159T>C; p.Y387H; 12:71572872-71572872	skin	malignant_melanoma	Substitution - Missense
c.516T>G; p.N172K; 12:71553160-71553160	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1836G>A; p.V612V; 12:71583846-71583846	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1064A>G; p.Q355R; 12:71566906-71566906	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1244_1245CC>TT; p.P415L; 12:71577960-71577961	skin	malignant_melanoma	Substitution - Missense
c.2127C>T; p.S709S; 12:71584137-71584137	skin	malignant_melanoma	Substitution - coding silent
c.1692G>A; p.V564V; 12:71583702-71583702	oesophagus; upper_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2141C>T; p.P714L; 12:71584151-71584151	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2307C>T; p.A769A; 12:71584317-71584317	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.498C>T; p.H166H; 12:71553142-71553142	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1513G>A; p.D505N; 12:71580384-71580384	skin; trunk	malignant_melanoma	Substitution - Missense
c.1A>G; p.M1V; 12:71440081-71440081	urinary_tract; bladder	carcinoma	Substitution - Missense
c.539A>C; p.Q180P; 12:71553183-71553183	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.885T>G; p.F295L; 12:71566431-71566431	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.761G>T; p.R254M; 12:71559630-71559630	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1998G>A; p.V666V; 12:71584008-71584008	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1461T>A; p.N487K; 12:71580332-71580332	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2531C>T; p.S844L; 12:71584541-71584541	skin	malignant_melanoma	Substitution - Missense
c.2579A>C; p.Q860P; 12:71584589-71584589	skin	malignant_melanoma	Substitution - Missense
c.1511A>T; p.D504V; 12:71580382-71580382	liver	carcinoma	Substitution - Missense
c.1552+1G>A; p.?; 12:71580424-71580424	stomach	carcinoma; adenocarcinoma	Unknown
c.2543G>T; p.S848I; 12:71584553-71584553	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2088C>T; p.A696A; 12:71584098-71584098	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2325C>A; p.N775K; 12:71584335-71584335	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1264C>T; p.P422S; 12:71577980-71577980	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1883G>C; p.G628A; 12:71583893-71583893	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1883G>C; p.G628A; 12:71583893-71583893	kidney	other; neoplasm	Substitution - Missense
c.2067C>T; p.A689A; 12:71584077-71584077	skin	malignant_melanoma	Substitution - coding silent
c.1126C>T; p.L376F; 12:71571569-71571569	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2292G>T; p.M764I; 12:71584302-71584302	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2022G>A; p.T674T; 12:71584032-71584032	skin	malignant_melanoma	Substitution - coding silent
c.539A>G; p.Q180R; 12:71553183-71553183	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2022G>A; p.T674T; 12:71584032-71584032	skin	malignant_melanoma	Substitution - coding silent
c.2644C>A; p.P882T; 12:71584654-71584654	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1070+1G>A; p.?; 12:71566913-71566913	urinary_tract; bladder	carcinoma	Unknown
c.2022G>A; p.T674T; 12:71584032-71584032	skin	malignant_melanoma	Substitution - coding silent
c.44T>C; p.L15P; 12:71440124-71440124	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1155A>C; p.E385D; 12:71572868-71572868	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1567G>C; p.E523Q; 12:71582470-71582470	breast	carcinoma	Substitution - Missense
c.285-5C>A; p.?; 12:71524401-71524401	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.57G>A; p.A19A; 12:71440137-71440137	breast	carcinoma	Substitution - coding silent
c.57G>A; p.A19A; 12:71440137-71440137	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.221G>T; p.S74I; 12:71504622-71504622	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1969C>G; p.L657V; 12:71583979-71583979	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2021C>T; p.T674M; 12:71584031-71584031	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2021C>T; p.T674M; 12:71584031-71584031	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.2428C>G; p.P810A; 12:71584438-71584438	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1644C>T; p.F548F; 12:71583654-71583654	skin	malignant_melanoma	Substitution - coding silent
c.2604G>A; p.L868L; 12:71584614-71584614	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2082C>T; p.T694T; 12:71584092-71584092	skin	malignant_melanoma	Substitution - coding silent
c.1385C>T; p.S462F; 12:71578908-71578908	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.473T>G; p.F158C; 12:71553117-71553117	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1640C>G; p.P547R; 12:71583650-71583650	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.807C>T; p.I269I; 12:71561802-71561802	skin	malignant_melanoma	Substitution - coding silent
c.2155G>C; p.E719Q; 12:71584165-71584165	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.2155G>C; p.E719Q; 12:71584165-71584165	urinary_tract; bladder	carcinoma	Substitution - Missense
c.33C>T; p.S11S; 12:71440113-71440113	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.812C>T; p.S271L; 12:71561807-71561807	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2418G>A; p.L806L; 12:71584428-71584428	skin	malignant_melanoma	Substitution - coding silent
c.812C>T; p.S271L; 12:71561807-71561807	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1048C>T; p.Q350*; 12:71566890-71566890	pancreas	carcinoid-endocrine_tumour; islet_cell	Substitution - Nonsense
c.225G>A; p.M75I; 12:71504626-71504626	skin	malignant_melanoma	Substitution - Missense
c.1934T>A; p.I645N; 12:71583944-71583944	skin	malignant_melanoma	Substitution - Missense
c.254C>T; p.P85L; 12:71504655-71504655	skin	malignant_melanoma	Substitution - Missense
c.991_992delGA; p.L333fs*20; 12:71566693-71566694	stomach	carcinoma; diffuse_adenocarcinoma	Deletion - Frameshift
c.177G>A; p.E59E; 12:71440257-71440257	pancreas	carcinoma; adenocarcinoma	Substitution - coding silent

The somatic mutations from COSMIC database