Entrez Gene

Basic Information
Gene ID	80310
Name	PDGFD

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.313G>T; p.E105*; 11:104000067-104000067	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.503C>A; p.S168Y; 11:103996072-103996072	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1109G>T; p.R370L; 11:103909698-103909698	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.805C>G; p.R269G; 11:103927094-103927094	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.189C>T; p.Y63Y; 11:104000191-104000191	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.75G>A; p.P25P; 11:104163853-104163853	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1025_1026insG; p.R343fs*1; 11:103909781-103909782	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.9G>A; p.R3R; 11:104163919-104163919	thyroid	other; neoplasm	Substitution - coding silent
c.667C>T; p.L223L; 11:103943557-103943557	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.184G>A; p.G62S; 11:104000196-104000196	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.184G>A; p.G62S; 11:104000196-104000196	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1080T>C; p.C360C; 11:103909727-103909727	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.361G>T; p.E121*; 11:103996214-103996214	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.895G>T; p.V299L; 11:103927004-103927004	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.510+2T>C; p.?; 11:103996063-103996063	stomach	carcinoma; adenocarcinoma	Unknown
c.160G>A; p.E54K; 11:104000220-104000220	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.920G>A; p.G307D; 11:103926979-103926979	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.422A>C; p.K141T; 11:103996153-103996153	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.37G>T; p.A13S; 11:104163891-104163891	liver	carcinoma	Substitution - Missense
c.37G>T; p.A13S; 11:104163891-104163891	liver	carcinoma	Substitution - Missense
c.459C>T; p.S153S; 11:103996116-103996116	prostate	adenoma	Substitution - coding silent
c.805C>T; p.R269C; 11:103927094-103927094	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.739C>T; p.R247*; 11:103943485-103943485	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.739C>T; p.R247*; 11:103943485-103943485	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.739C>T; p.R247*; 11:103943485-103943485	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.619G>A; p.A207T; 11:103943605-103943605	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.355A>C; p.I119L; 11:103996220-103996220	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.771A>C; p.K257N; 11:103943453-103943453	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.747G>A; p.R249R; 11:103943477-103943477	skin	malignant_melanoma	Substitution - coding silent
c.637A>C; p.K213Q; 11:103943587-103943587	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.621G>A; p.A207A; 11:103943603-103943603	stomach	adenocarcinoma	Substitution - coding silent
c.603G>A; p.T201T; 11:103943621-103943621	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - coding silent
c.810C>T; p.Y270Y; 11:103927089-103927089	liver	carcinoma	Substitution - coding silent
c.111C>A; p.N37K; 11:104163817-104163817	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1091G>A; p.C364Y; 11:103909716-103909716	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.273A>G; p.I91M; 11:104000107-104000107	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1058A>G; p.Q353R; 11:103909749-103909749	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.607C>T; p.P203S; 11:103943617-103943617	skin	malignant_melanoma	Substitution - Missense
c.453C>T; p.F151F; 11:103996122-103996122	skin	malignant_melanoma	Substitution - coding silent
c.208C>T; p.P70S; 11:104000172-104000172	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.336T>G; p.D112E; 11:103996239-103996239	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1A>T; p.M1L; 11:104163927-104163927	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.179G>A; p.G60E; 11:104000201-104000201	skin	malignant_melanoma	Substitution - Missense
c.654T>C; p.D218D; 11:103943570-103943570	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.977A>G; p.K326R; 11:103926922-103926922	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.384A>G; p.G128G; 11:103996191-103996191	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.381A>C; p.R127S; 11:103996194-103996194	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.319G>C; p.D107H; 11:104000061-104000061	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.183C>T; p.N61N; 11:104000197-104000197	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.719A>G; p.Y240C; 11:103943505-103943505	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.566C>G; p.S189C; 11:103947669-103947669	prostate	carcinoma	Substitution - Missense
c.1004C>A; p.P335H; 11:103909803-103909803	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.212A>G; p.N71S; 11:104000168-104000168	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.683A>C; p.N228T; 11:103943541-103943541	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.604G>T; p.D202Y; 11:103943620-103943620	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.950C>T; p.T317I; 11:103926949-103926949	skin	malignant_melanoma	Substitution - Missense
c.781G>A; p.D261N; 11:103927118-103927118	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1081G>A; p.D361N; 11:103909726-103909726	skin	malignant_melanoma	Substitution - Missense
c.883C>T; p.R295C; 11:103927016-103927016	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1108C>T; p.R370*; 11:103909699-103909699	skin	malignant_melanoma	Substitution - Nonsense
c.207C>T; p.F69F; 11:104000173-104000173	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.74C>T; p.P25L; 11:104163854-104163854	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.28_29delCT; p.L10fs*32; 11:104163899-104163900	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.902G>A; p.R301H; 11:103926997-103926997	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.638A>C; p.K213T; 11:103943586-103943586	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.753C>T; p.Y251Y; 11:103943471-103943471	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1097C>T; p.S366L; 11:103909710-103909710	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.686C>T; p.P229L; 11:103943538-103943538	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.760C>T; p.R254W; 11:103943464-103943464	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.969C>T; p.T323T; 11:103926930-103926930	bone; fibula	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.57G>A; p.R19R; 11:104163871-104163871	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.620C>T; p.A207V; 11:103943604-103943604	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.620C>T; p.A207V; 11:103943604-103943604	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.82G>A; p.A28T; 11:104163846-104163846	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.82G>A; p.A28T; 11:104163846-104163846	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.428G>T; p.R143I; 11:103996147-103996147	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.428G>T; p.R143I; 11:103996147-103996147	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.901C>T; p.R301C; 11:103926998-103926998	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.6C>G; p.H2Q; 11:104163922-104163922	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.806G>A; p.R269H; 11:103927093-103927093	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.806G>A; p.R269H; 11:103927093-103927093	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.838A>G; p.N280D; 11:103927061-103927061	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.806G>A; p.R269H; 11:103927093-103927093	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.265A>G; p.T89A; 11:104000115-104000115	ovary	other; neoplasm	Substitution - Missense
c.695G>T; p.W232L; 11:103943529-103943529	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.834G>A; p.S278S; 11:103927065-103927065	large_intestine; colon	NS	Substitution - coding silent
c.1050T>G; p.V350V; 11:103909757-103909757	stomach	adenocarcinoma	Substitution - coding silent
c.73C>A; p.P25T; 11:104163855-104163855	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.73C>A; p.P25T; 11:104163855-104163855	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.190G>A; p.V64M; 11:104000190-104000190	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1075C>T; p.R359*; 11:103909732-103909732	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.190G>A; p.V64M; 11:104000190-104000190	prostate	carcinoma	Substitution - Missense
c.1075C>T; p.R359*; 11:103909732-103909732	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.355A>G; p.I119V; 11:103996220-103996220	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.414A>T; p.P138P; 11:103996161-103996161	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.572C>T; p.S191L; 11:103947663-103947663	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.606T>C; p.D202D; 11:103943618-103943618	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.606T>C; p.D202D; 11:103943618-103943618	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.852G>T; p.E284D; 11:103927047-103927047	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.432G>A; p.T144T; 11:103996143-103996143	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.432G>A; p.T144T; 11:103996143-103996143	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.644C>T; p.A215V; 11:103943580-103943580	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.256C>T; p.Q86*; 11:104000124-104000124	central_nervous_system; brain	glioma	Substitution - Nonsense
c.861G>T; p.L287F; 11:103927038-103927038	prostate	carcinoma	Substitution - Missense
c.803A>G; p.K268R; 11:103927096-103927096	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.101G>A; p.R34H; 11:104163827-104163827	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.806G>T; p.R269L; 11:103927093-103927093	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.571T>G; p.S191A; 11:103947664-103947664	skin	malignant_melanoma	Substitution - Missense
c.287A>G; p.D96G; 11:104000093-104000093	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.640delA; p.I214fs*68; 11:103943584-103943584	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.640delA; p.I214fs*68; 11:103943584-103943584	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.640delA; p.I214fs*68; 11:103943584-103943584	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.811A>C; p.S271R; 11:103927088-103927088	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.970G>A; p.V324M; 11:103926929-103926929	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.602C>T; p.T201M; 11:103943622-103943622	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1034A>G; p.K345R; 11:103909773-103909773	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.741A>T; p.R247R; 11:103943483-103943483	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.478delA; p.K160fs*41; 11:103996097-103996097	lung	carcinoma; non_small_cell_carcinoma	Deletion - Frameshift
c.78G>C; p.Q26H; 11:104163850-104163850	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.605A>G; p.D202G; 11:103943619-103943619	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.605A>G; p.D202G; 11:103943619-103943619	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.78G>C; p.Q26H; 11:104163850-104163850	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.799G>T; p.A267S; 11:103927100-103927100	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.799G>T; p.A267S; 11:103927100-103927100	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.100C>T; p.R34C; 11:104163828-104163828	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.19G>A; p.V7I; 11:104163909-104163909	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.93A>C; p.K31N; 11:104163835-104163835	stomach	carcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	Substitution - Missense
c.1046T>C; p.L349P; 11:103909761-103909761	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.19G>A; p.V7I; 11:104163909-104163909	liver	carcinoma	Substitution - Missense
c.604G>A; p.D202N; 11:103943620-103943620	skin	malignant_melanoma	Substitution - Missense
c.604G>A; p.D202N; 11:103943620-103943620	skin	malignant_melanoma	Substitution - Missense
c.604G>A; p.D202N; 11:103943620-103943620	skin	malignant_melanoma	Substitution - Missense

The somatic mutations from COSMIC database