Entrez Gene

Basic Information
Gene ID	80204
Name	FBXO11

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.808T>G; p.S270A; 2:47832862-47832862	liver	carcinoma	Substitution - Missense
c.808T>G; p.S270A; 2:47832862-47832862	liver	carcinoma	Substitution - Missense
c.1891A>C; p.K631Q; 2:47813318-47813318	haematopoietic_and_lymphoid_tissue; groin	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1625G>T; p.S542I; 2:47818999-47818999	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1702G>C; p.V568L; 2:47818831-47818831	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1996_2027del32; p.I666fs*3; 2:47810375-47810406	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.1325C>A; p.A442E; 2:47823182-47823182	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1748A>C; p.Q583P; 2:47818785-47818785	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.111C>T; p.G37G; 2:47839498-47839498	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.2239A>G; p.S747G; 2:47809222-47809222	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; angioimmunoblastic_T_cell_lymphoma	Substitution - Missense
c.303C>A; p.R101R; 2:47838891-47838891	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.332T>C; p.L111S; 2:47838862-47838862	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.146G>C; p.R49P; 2:47839463-47839463	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.904G>A; p.G302S; 2:47832676-47832676	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.904G>A; p.G302S; 2:47832676-47832676	liver	carcinoma	Substitution - Missense
c.719delA; p.N240fs*21; 2:47833034-47833034	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.719delA; p.N240fs*21; 2:47833034-47833034	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2054G>T; p.R685M; 2:47810348-47810348	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.2054G>T; p.R685M; 2:47810348-47810348	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.24T>C; p.P8P; 2:47839726-47839726	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.363A>G; p.E121E; 2:47835974-47835974	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2052A>C; p.L684F; 2:47810350-47810350	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.914T>C; p.V305A; 2:47832666-47832666	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.407A>G; p.Q136R; 2:47835930-47835930	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2489A>G; p.D830G; 2:47808161-47808161	liver	carcinoma	Substitution - Missense
c.844A>T; p.I282F; 2:47832826-47832826	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2441C>A; p.P814H; 2:47808209-47808209	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1976-2A>G; p.?; 2:47810428-47810428	stomach	adenocarcinoma	Unknown
c.1778G>C; p.R593T; 2:47813844-47813844	thyroid	carcinoma	Substitution - Missense
c.214C>T; p.Q72*; 2:47838980-47838980	thyroid	carcinoma	Substitution - Nonsense
c.873T>A; p.D291E; 2:47832797-47832797	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1212T>C; p.A404A; 2:47823295-47823295	skin	malignant_melanoma	Substitution - coding silent
c.35A>G; p.N12S; 2:47839715-47839715	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.161G>C; p.R54T; 2:47839448-47839448	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2481_2482delAC; p.L828fs*2; 2:47808168-47808169	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.601G>A; p.D201N; 2:47834660-47834660	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1219A>G; p.T407A; 2:47823288-47823288	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.241C>A; p.L81I; 2:47838953-47838953	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1744G>T; p.V582F; 2:47818789-47818789	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Burkitt_lymphoma	Substitution - Missense
c.1989A>G; p.E663E; 2:47810413-47810413	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2502T>G; p.P834P; 2:47808148-47808148	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.700_703delGACA; p.D234fs*3; 2:47833050-47833053	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.503A>G; p.H168R; 2:47834834-47834834	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1675G>A; p.V559I; 2:47818858-47818858	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1044G>A; p.A348A; 2:47832451-47832451	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.105G>A; p.M35I; 2:47839645-47839645	pancreas	carcinoma	Substitution - Missense
c.134A>G; p.N45S; 2:47839475-47839475	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2096T>A; p.I699N; 2:47809698-47809698	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Burkitt_lymphoma	Substitution - Missense
c.1570G>T; p.E524*; 2:47819054-47819054	breast	carcinoma	Substitution - Nonsense
c.1463C>A; p.A488E; 2:47820444-47820444	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; angioimmunoblastic_T_cell_lymphoma	Substitution - Missense
c.866T>A; p.I289N; 2:47832804-47832804	skin	malignant_melanoma	Substitution - Missense
c.365A>G; p.Y122C; 2:47835972-47835972	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.2146C>T; p.R716W; 2:47809648-47809648	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1173C>A; p.H391Q; 2:47823334-47823334	breast	carcinoma	Substitution - Missense
c.901G>T; p.V301F; 2:47832769-47832769	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1442A>G; p.D481G; 2:47822226-47822226	lung; left_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.871G>C; p.D291H; 2:47832799-47832799	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2178_2179insTC; p.N727fs*3; 2:47809615-47809616	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - Frameshift
c.1147-9A>G; p.?; 2:47823369-47823369	liver	carcinoma	Unknown
c.1147-9A>G; p.?; 2:47823369-47823369	liver	carcinoma	Unknown
c.1151A>T; p.Y384F; 2:47823356-47823356	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1371T>G; p.N457K; 2:47822297-47822297	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.702_703delCA; p.D234fs*5; 2:47833050-47833051	haematopoietic_and_lymphoid_tissue; skin	lymphoid_neoplasm; follicular_lymphoma	Deletion - Frameshift
c.1946G>T; p.G649V; 2:47813263-47813263	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.376A>G; p.M126V; 2:47835961-47835961	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2486A>G; p.Y829C; 2:47808164-47808164	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.71C>T; p.P24L; 2:47839679-47839679	skin	malignant_melanoma	Substitution - Missense
c.376A>G; p.M126V; 2:47835961-47835961	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1975G>A; p.G659S; 2:47813234-47813234	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.2071G>C; p.D691H; 2:47810331-47810331	skin	malignant_melanoma	Substitution - Missense
c.272A>G; p.D91G; 2:47838922-47838922	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.460C>T; p.Q154*; 2:47835877-47835877	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.254C>T; p.S85F; 2:47838940-47838940	skin	malignant_melanoma	Substitution - Missense
c.254C>T; p.S85F; 2:47838940-47838940	skin	malignant_melanoma	Substitution - Missense
c.2532A>T; p.*844C; 2:47808118-47808118	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Nonstop extension
c.841G>A; p.E281K; 2:47832829-47832829	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.57A>G; p.R19R; 2:47839693-47839693	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2222C>A; p.A741D; 2:47809239-47809239	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2429C>T; p.T810I; 2:47808221-47808221	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1829C>T; p.S610F; 2:47813793-47813793	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.328A>G; p.I110V; 2:47838866-47838866	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1748A>T; p.Q583L; 2:47818785-47818785	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2082C>T; p.A694A; 2:47810320-47810320	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1625G>A; p.S542N; 2:47818999-47818999	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1440T>C; p.N480N; 2:47822228-47822228	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1682T>G; p.F561C; 2:47818851-47818851	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2416T>G; p.C806G; 2:47808234-47808234	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1743G>T; p.G581G; 2:47818790-47818790	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2139delT; p.F713fs*10; 2:47809655-47809655	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.887G>A; p.R296Q; 2:47832783-47832783	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2198A>T; p.N733I; 2:47809263-47809263	skin	malignant_melanoma	Substitution - Missense
c.2387T>G; p.F796C; 2:47808344-47808344	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2387T>G; p.F796C; 2:47808344-47808344	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2476G>T; p.D826Y; 2:47808174-47808174	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.395G>A; p.G132E; 2:47835942-47835942	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2338A>T; p.I780L; 2:47808393-47808393	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.412A>G; p.N138D; 2:47835925-47835925	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1799G>A; p.G600E; 2:47813823-47813823	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1595C>G; p.T532S; 2:47819029-47819029	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1043C>T; p.A348V; 2:47832452-47832452	large_intestine; colon	NS	Substitution - Missense
c.1043C>T; p.A348V; 2:47832452-47832452	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1170A>G; p.I390M; 2:47823337-47823337	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1043C>T; p.A348V; 2:47832452-47832452	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1043C>T; p.A348V; 2:47832452-47832452	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.301C>T; p.R101C; 2:47838893-47838893	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1493C>T; p.P498L; 2:47820414-47820414	skin	malignant_melanoma	Substitution - Missense
c.368C>T; p.T123I; 2:47835969-47835969	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2263A>G; p.I755V; 2:47809198-47809198	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.229G>A; p.D77N; 2:47838965-47838965	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.297T>C; p.C99C; 2:47838897-47838897	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.809C>A; p.S270Y; 2:47832861-47832861	liver	carcinoma	Substitution - Missense
c.297T>C; p.C99C; 2:47838897-47838897	thyroid	carcinoma	Substitution - coding silent
c.809C>A; p.S270Y; 2:47832861-47832861	liver	carcinoma	Substitution - Missense
c.1254T>A; p.T418T; 2:47823253-47823253	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.84G>A; p.A28A; 2:47839666-47839666	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.199G>T; p.A67S; 2:47838995-47838995	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1706T>C; p.L569P; 2:47818827-47818827	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Burkitt_lymphoma	Substitution - Missense
c.2180A>C; p.N727T; 2:47809614-47809614	liver	carcinoma	Substitution - Missense
c.323A>T; p.D108V; 2:47838871-47838871	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1519G>A; p.D507N; 2:47820388-47820388	breast	carcinoma	Substitution - Missense
c.2107G>A; p.A703T; 2:47809687-47809687	large_intestine; colon	NS	Substitution - Missense
c.730T>G; p.S244A; 2:47833023-47833023	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2304-2A>G; p.?; 2:47808429-47808429	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Unknown
c.1811G>A; p.G604E; 2:47813811-47813811	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.2459A>G; p.E820G; 2:47808191-47808191	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1731T>C; p.H577H; 2:47818802-47818802	liver	carcinoma	Substitution - coding silent
c.1669-10T>A; p.?; 2:47818874-47818874	pancreas	carcinoma	Unknown
c.1669-10T>A; p.?; 2:47818874-47818874	prostate	carcinoma; adenocarcinoma	Unknown
c.2472T>C; p.D824D; 2:47808178-47808178	liver	carcinoma	Substitution - coding silent
c.1553A>G; p.K518R; 2:47819071-47819071	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2340A>G; p.I780M; 2:47808391-47808391	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1214A>G; p.N405S; 2:47823293-47823293	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1832-2A>G; p.?; 2:47813379-47813379	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Burkitt_lymphoma	Unknown
c.1748A>G; p.Q583R; 2:47818785-47818785	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.466-2A>C; p.?; 2:47834873-47834873	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Unknown
c.1439A>G; p.N480S; 2:47822229-47822229	breast	carcinoma	Substitution - Missense
c.1675G>T; p.V559F; 2:47818858-47818858	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1893G>C; p.K631N; 2:47813316-47813316	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.2452G>T; p.A818S; 2:47808198-47808198	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1611G>T; p.W537C; 2:47819013-47819013	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_associated_with_MDS	Substitution - Missense
c.1975+2T>C; p.?; 2:47813232-47813232	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.1335G>C; p.W445C; 2:47823172-47823172	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Substitution - Missense
c.1679A>G; p.Y560C; 2:47818854-47818854	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1679A>G; p.Y560C; 2:47818854-47818854	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1892A>C; p.K631T; 2:47813317-47813317	skin	malignant_melanoma	Substitution - Missense
c.2336C>T; p.A779V; 2:47808395-47808395	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.370C>T; p.R124C; 2:47835967-47835967	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.56G>T; p.R19I; 2:47839694-47839694	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.997_997G>AA; p.D333fs*8; 2:47832583-47832583	haematopoietic_and_lymphoid_tissue; groin	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Complex - frameshift
c.2298C>A; p.F766L; 2:47809163-47809163	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1331T>C; p.V444A; 2:47823176-47823176	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2366A>G; p.H789R; 2:47808365-47808365	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.1535G>A; p.G512E; 2:47820372-47820372	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2087-1G>C; p.?; 2:47809708-47809708	skin	malignant_melanoma	Unknown
c.2367T>A; p.H789Q; 2:47808364-47808364	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2163T>A; p.F721L; 2:47809631-47809631	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2338A>G; p.I780V; 2:47808393-47808393	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2338A>G; p.I780V; 2:47808393-47808393	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2037_2039TAG>G; p.N679fs*12; 2:47810363-47810365	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Burkitt_lymphoma	Complex - frameshift
c.2006A>G; p.N669S; 2:47810396-47810396	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Substitution - Missense
c.2509T>G; p.S837A; 2:47808141-47808141	liver	carcinoma	Substitution - Missense
c.288T>C; p.A96A; 2:47838906-47838906	skin	malignant_melanoma	Substitution - coding silent

The somatic mutations from COSMIC database