Entrez Gene

Basic Information
Gene ID	79727
Name	LIN28A

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.615G>A; p.P205P; 1:26426443-26426443	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.201delC; p.P69fs*19; 1:26411555-26411555	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.504C>T; p.S168S; 1:26426332-26426332	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.148C>T; p.R50C; 1:26411502-26411502	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.606C>T; p.T202T; 1:26426434-26426434	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.518C>G; p.S173*; 1:26426346-26426346	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.297G>C; p.K99N; 1:26425371-26425371	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.616G>A; p.E206K; 1:26426444-26426444	skin	malignant_melanoma	Substitution - Missense
c.442C>T; p.H148Y; 1:26426270-26426270	urinary_tract; bladder	carcinoma	Substitution - Missense
c.123G>A; p.A41A; 1:26411477-26411477	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.439C>A; p.H147N; 1:26426267-26426267	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.415T>A; p.C139S; 1:26426243-26426243	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.387G>A; p.M129I; 1:26425461-26425461	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.194C>T; p.A65V; 1:26411548-26411548	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.186C>T; p.A62A; 1:26411540-26411540	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.125G>A; p.G42D; 1:26411479-26411479	central_nervous_system; brain	glioma	Substitution - Missense
c.567C>G; p.T189T; 1:26426395-26426395	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.624G>T; p.Q208H; 1:26426452-26426452	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.25delT; p.F9fs*50; 1:26410916-26410916	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Deletion - Frameshift
c.159C>T; p.F53F; 1:26411513-26411513	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.312G>A; p.L104L; 1:26425386-26425386	skin	malignant_melanoma	Substitution - coding silent
c.629G>A; p.210; 1:26426457-26426457	skin	malignant_melanoma	Substitution - coding silent
c.601C>T; p.P201S; 1:26426429-26426429	skin	malignant_melanoma	Substitution - Missense
c.574C>T; p.R192*; 1:26426402-26426402	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.574C>T; p.R192*; 1:26426402-26426402	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.355G>A; p.G119R; 1:26425429-26425429	skin	malignant_melanoma	Substitution - Missense
c.570C>T; p.Y190Y; 1:26426398-26426398	skin	malignant_melanoma	Substitution - coding silent
c.226-7C>T; p.?; 1:26425293-26425293	liver	carcinoma	Unknown
c.226-7C>T; p.?; 1:26425293-26425293	liver	carcinoma	Unknown
c.126C>T; p.G42G; 1:26411480-26411480	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.98A>G; p.D33G; 1:26411452-26411452	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.369G>A; p.R123R; 1:26425443-26425443	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.50C>A; p.A17E; 1:26411404-26411404	breast	carcinoma	Substitution - Missense
c.122C>T; p.A41V; 1:26411476-26411476	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.11T>C; p.V4A; 1:26410902-26410902	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.335C>T; p.P112L; 1:26425409-26425409	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.614C>A; p.P205Q; 1:26426442-26426442	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.436G>A; p.D146N; 1:26426264-26426264	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.377G>A; p.G126E; 1:26425451-26425451	skin	malignant_melanoma	Substitution - Missense
c.377G>A; p.G126E; 1:26425451-26425451	skin	malignant_melanoma	Substitution - Missense
c.330C>T; p.T110T; 1:26425404-26425404	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.253C>T; p.R85W; 1:26425327-26425327	skin	malignant_melanoma	Substitution - Missense
c.85G>A; p.A29T; 1:26411439-26411439	pancreas	carcinoma	Substitution - Missense

The somatic mutations from COSMIC database