Entrez Gene

Basic Information
Gene ID	7043
Name	TGFB3

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.170delC; p.P57fs*5; 14:75980724-75980724	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.865G>A; p.D289N; 14:75963377-75963377	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1084C>T; p.L362L; 14:75959342-75959342	pancreas	carcinoma	Substitution - coding silent
c.580C>T; p.R194W; 14:75971192-75971192	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.865G>A; p.D289N; 14:75963377-75963377	oesophagus	carcinoma	Substitution - Missense
c.384C>T; p.T128T; 14:75971687-75971687	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.369C>T; p.C123C; 14:75971702-75971702	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.369C>T; p.C123C; 14:75971702-75971702	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.412T>G; p.S138A; 14:75971659-75971659	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1178G>A; p.G393E; 14:75959248-75959248	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.351C>T; p.H117H; 14:75980543-75980543	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1029C>A; p.F343L; 14:75960974-75960974	thyroid	other; neoplasm	Substitution - Missense
c.107A>G; p.K36R; 14:75980787-75980787	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1170C>A; p.Y390*; 14:75959256-75959256	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.354C>T; p.N118N; 14:75971717-75971717	NS	NS	Substitution - coding silent
c.625C>T; p.R209C; 14:75971147-75971147	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.610G>A; p.V204I; 14:75971162-75971162	breast	carcinoma	Substitution - Missense
c.597G>A; p.W199*; 14:75971175-75971175	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.597G>A; p.W199*; 14:75971175-75971175	stomach	adenocarcinoma	Substitution - Nonsense
c.796C>T; p.R266C; 14:75963446-75963446	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.796C>T; p.R266C; 14:75963446-75963446	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.611T>A; p.V204D; 14:75971161-75971161	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.859C>T; p.R287W; 14:75963383-75963383	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.196C>A; p.P66T; 14:75980698-75980698	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.979G>C; p.D327H; 14:75961024-75961024	urinary_tract; bladder	carcinoma	Substitution - Missense
c.376G>A; p.G126R; 14:75971695-75971695	skin; upper_leg	malignant_melanoma	Substitution - Missense
c.495G>A; p.E165E; 14:75971576-75971576	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.258G>A; p.E86E; 14:75980636-75980636	breast	carcinoma	Substitution - coding silent
c.6G>A; p.K2K; 14:75980888-75980888	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.457delG; p.V153fs*61; 14:75971614-75971614	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.524G>A; p.R175Q; 14:75971248-75971248	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.324C>T; p.F108F; 14:75980570-75980570	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.324C>T; p.F108F; 14:75980570-75980570	skin	malignant_melanoma	Substitution - coding silent
c.523C>T; p.R175W; 14:75971249-75971249	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1014C>A; p.G338G; 14:75960989-75960989	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.952C>T; p.R318C; 14:75961051-75961051	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.891G>A; p.R297R; 14:75963351-75963351	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.639G>C; p.L213F; 14:75971133-75971133	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.804G>A; p.K268K; 14:75963438-75963438	skin	malignant_melanoma	Substitution - coding silent
c.425delA; p.N142fs*72; 14:75971646-75971646	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1080+1G>A; p.?; 14:75960922-75960922	stomach	carcinoma; adenocarcinoma	Unknown
c.1080+1G>A; p.?; 14:75960922-75960922	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.267A>C; p.E89D; 14:75980627-75980627	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.506A>C; p.E169A; 14:75971565-75971565	liver	carcinoma	Substitution - Missense
c.506A>C; p.E169A; 14:75971565-75971565	liver	carcinoma	Substitution - Missense
c.688C>T; p.H230Y; 14:75965654-75965654	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.284A>G; p.N95S; 14:75980610-75980610	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.505G>A; p.E169K; 14:75971566-75971566	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1126C>T; p.P376S; 14:75959300-75959300	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.53C>T; p.A18V; 14:75980841-75980841	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.53C>T; p.A18V; 14:75980841-75980841	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.598C>A; p.L200M; 14:75971174-75971174	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.513C>T; p.F171F; 14:75971558-75971558	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.755-1G>C; p.?; 14:75963488-75963488	liver	carcinoma	Unknown
c.755-1G>C; p.?; 14:75963488-75963488	liver	carcinoma	Unknown
c.293C>T; p.S98L; 14:75980601-75980601	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.578C>T; p.T193I; 14:75971194-75971194	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.884delG; p.G295fs*74; 14:75963358-75963358	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.153C>T; p.L51L; 14:75980741-75980741	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.797G>A; p.R266H; 14:75963445-75963445	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.804G>T; p.K268N; 14:75963438-75963438	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.276C>A; p.T92T; 14:75980618-75980618	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1055G>A; p.R352H; 14:75960948-75960948	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.781C>A; p.R261S; 14:75963461-75963461	skin	malignant_melanoma	Substitution - Missense
c.590C>T; p.A197V; 14:75971182-75971182	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1229A>C; p.K410T; 14:75959197-75959197	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.714C>A; p.I238I; 14:75965628-75965628	kidney	other; neoplasm	Substitution - coding silent
c.430A>G; p.T144A; 14:75971641-75971641	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.463C>T; p.R155W; 14:75971608-75971608	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.240G>T; p.L80L; 14:75980654-75980654	breast	carcinoma	Substitution - coding silent
c.646+1G>A; p.?; 14:75971125-75971125	skin	malignant_melanoma	Unknown
c.972C>T; p.F324F; 14:75961031-75961031	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.454C>T; p.R152W; 14:75971617-75971617	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6G>T; p.K2N; 14:75980888-75980888	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense

The somatic mutations from COSMIC database