Entrez Gene

Basic Information
Gene ID	6862
Name	T

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.349C>A; p.P117T; 6:166166714-166166714	breast	carcinoma	Substitution - Missense
c.358C>T; p.P120S; 6:166166705-166166705	skin	malignant_melanoma	Substitution - Missense
c.1130G>A; p.R377Q; 6:166158493-166158493	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.958T>G; p.W320G; 6:166160913-166160913	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.351G>A; p.P117P; 6:166166712-166166712	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1292C>T; p.S431L; 6:166158331-166158331	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.510C>T; p.I170I; 6:166165802-166165802	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.510C>T; p.I170I; 6:166165802-166165802	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.247delG; p.D83fs*23; 6:166166816-166166816	breast	carcinoma	Deletion - Frameshift
c.296A>G; p.N99S; 6:166166767-166166767	skin	malignant_melanoma	Substitution - Missense
c.308A>G; p.K103R; 6:166166755-166166755	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1141G>A; p.A381T; 6:166158482-166158482	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1141G>A; p.A381T; 6:166158482-166158482	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.350C>T; p.P117L; 6:166166713-166166713	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.276G>T; p.L92L; 6:166166787-166166787	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.350C>T; p.P117L; 6:166166713-166166713	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.638T>G; p.F213C; 6:166164830-166164830	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.415G>T; p.A139S; 6:166166648-166166648	soft_tissue; striated_muscle	rhabdomyosarcoma	Substitution - Missense
c.664G>A; p.E222K; 6:166164804-166164804	skin	malignant_melanoma	Substitution - Missense
c.382G>A; p.D128N; 6:166166681-166166681	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.749G>A; p.G250E; 6:166162602-166162602	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.267C>A; p.S89S; 6:166166796-166166796	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.762G>C; p.L254L; 6:166162589-166162589	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.256G>A; p.A86T; 6:166166807-166166807	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1028G>T; p.S343I; 6:166160843-166160843	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.256G>A; p.A86T; 6:166166807-166166807	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.567G>C; p.E189D; 6:166165745-166165745	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.66C>T; p.S22S; 6:166167526-166167526	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.130G>A; p.V44M; 6:166167462-166167462	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.21G>A; p.E7E; 6:166167571-166167571	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1176G>A; p.A392A; 6:166158447-166158447	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1043C>T; p.P348L; 6:166158580-166158580	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1281G>A; p.W427*; 6:166158342-166158342	skin	malignant_melanoma	Substitution - Nonsense
c.1218G>A; p.A406A; 6:166158405-166158405	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.970G>A; p.G324R; 6:166160901-166160901	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.387G>A; p.S129S; 6:166166676-166166676	skin	malignant_melanoma	Substitution - coding silent
c.387G>A; p.S129S; 6:166166676-166166676	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1198C>A; p.L400M; 6:166158425-166158425	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.287C>T; p.A96V; 6:166166776-166166776	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.287C>T; p.A96V; 6:166166776-166166776	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.841A>G; p.T281A; 6:166162510-166162510	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.270C>A; p.F90L; 6:166166793-166166793	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.37C>A; p.L13M; 6:166167555-166167555	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.519G>C; p.V173V; 6:166165793-166165793	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.396C>A; p.F132L; 6:166166667-166166667	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1258C>G; p.Q420E; 6:166158365-166158365	breast	carcinoma	Substitution - Missense
c.1207G>T; p.G403W; 6:166158416-166158416	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1000G>T; p.V334L; 6:166160871-166160871	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.563C>T; p.P188L; 6:166165749-166165749	central_nervous_system; brain	glioma	Substitution - Missense
c.1044C>A; p.P348P; 6:166158579-166158579	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1162C>T; p.H388Y; 6:166158461-166158461	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1265G>A; p.R422H; 6:166158358-166158358	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.252C>T; p.P84P; 6:166166811-166166811	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.986C>T; p.P329L; 6:166160885-166160885	stomach	adenocarcinoma	Substitution - Missense
c.815C>T; p.S272F; 6:166162536-166162536	skin	malignant_melanoma	Substitution - Missense
c.363C>T; p.S121S; 6:166166700-166166700	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.815C>T; p.S272F; 6:166162536-166162536	skin; trunk	malignant_melanoma	Substitution - Missense
c.1269C>G; p.L423L; 6:166158354-166158354	breast	carcinoma	Substitution - coding silent
c.381C>A; p.P127P; 6:166166682-166166682	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.846G>T; p.L282L; 6:166162505-166162505	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.144G>A; p.E48E; 6:166167448-166167448	stomach	adenocarcinoma	Substitution - coding silent
c.491A>T; p.H164L; 6:166165821-166165821	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.181G>C; p.E61Q; 6:166167411-166167411	urinary_tract; bladder	carcinoma	Substitution - Missense
c.530G>A; p.G177D; 6:166165782-166165782	thyroid	other; neoplasm	Substitution - Missense
c.1045A>T; p.S349C; 6:166158578-166158578	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1216G>T; p.A406S; 6:166158407-166158407	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.870C>T; p.Y290Y; 6:166162481-166162481	breast	carcinoma	Substitution - coding silent
c.1216G>A; p.A406T; 6:166158407-166158407	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1216G>A; p.A406T; 6:166158407-166158407	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1216G>A; p.A406T; 6:166158407-166158407	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1125C>T; p.F375F; 6:166158498-166158498	skin	malignant_melanoma	Substitution - coding silent
c.722A>C; p.Y241S; 6:166164613-166164613	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.730+5G>T; p.?; 6:166164600-166164600	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.1274C>T; p.A425V; 6:166158349-166158349	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1242G>A; p.Q414Q; 6:166158381-166158381	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.851G>A; p.S284N; 6:166162500-166162500	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.420C>T; p.P140P; 6:166166643-166166643	prostate	carcinoma	Substitution - coding silent
c.735delG; p.W246fs*37; 6:166162616-166162616	lung	carcinoma; small_cell_carcinoma	Deletion - Frameshift
c.854A>T; p.H285L; 6:166162497-166162497	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1136C>G; p.S379C; 6:166158487-166158487	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1249G>A; p.A417T; 6:166158374-166158374	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1246G>A; p.D416N; 6:166158377-166158377	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1246G>A; p.D416N; 6:166158377-166158377	skin	malignant_melanoma	Substitution - Missense
c.1246G>A; p.D416N; 6:166158377-166158377	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.357G>A; p.A119A; 6:166166706-166166706	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.634C>T; p.P212S; 6:166164834-166164834	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1111C>A; p.L371M; 6:166158512-166158512	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.140A>T; p.E47V; 6:166167452-166167452	skin	malignant_melanoma	Substitution - Missense
c.169G>A; p.E57K; 6:166167423-166167423	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1139C>T; p.P380L; 6:166158484-166158484	skin	malignant_melanoma	Substitution - Missense
c.1071C>T; p.A357A; 6:166158552-166158552	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.288G>A; p.A96A; 6:166166775-166166775	pancreas	carcinoma	Substitution - coding silent
c.613G>A; p.A205T; 6:166164855-166164855	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.613G>A; p.A205T; 6:166164855-166164855	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.460G>A; p.G154R; 6:166166603-166166603	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.142G>C; p.E48Q; 6:166167450-166167450	skin	malignant_melanoma	Substitution - Missense
c.1066G>A; p.G356S; 6:166158557-166158557	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1107C>T; p.N369N; 6:166158516-166158516	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1066G>A; p.G356S; 6:166158557-166158557	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.119G>A; p.R40H; 6:166167473-166167473	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.119G>A; p.R40H; 6:166167473-166167473	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.819G>A; p.T273T; 6:166162532-166162532	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.306G>A; p.W102*; 6:166166757-166166757	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.40C>T; p.Q14*; 6:166167552-166167552	pancreas	carcinoma	Substitution - Nonsense
c.1249G>T; p.A417S; 6:166158374-166158374	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.93C>T; p.G31G; 6:166167499-166167499	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.401C>G; p.A134G; 6:166166662-166166662	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.780T>G; p.P260P; 6:166162571-166162571	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1131G>T; p.R377R; 6:166158492-166158492	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1131G>T; p.R377R; 6:166158492-166158492	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.210G>A; p.R70R; 6:166166853-166166853	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1165C>A; p.P389T; 6:166158458-166158458	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.890G>A; p.R297Q; 6:166162461-166162461	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.834G>T; p.R278S; 6:166162517-166162517	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.392A>G; p.N131S; 6:166166671-166166671	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.298C>T; p.H100Y; 6:166166765-166166765	pancreas	NS	Substitution - Missense
c.1099G>A; p.V367M; 6:166158524-166158524	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.318C>T; p.N106N; 6:166166745-166166745	pancreas	carcinoma	Substitution - coding silent
c.318C>T; p.N106N; 6:166166745-166166745	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.318C>T; p.N106N; 6:166166745-166166745	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.318C>T; p.N106N; 6:166166745-166166745	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.346_347delGA; p.E116fs*49; 6:166166716-166166717	autonomic_ganglia	neuroblastoma	Deletion - Frameshift
c.756C>A; p.S252R; 6:166162595-166162595	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.366C>T; p.C122C; 6:166166697-166166697	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.366C>T; p.C122C; 6:166166697-166166697	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1251C>T; p.A417A; 6:166158372-166158372	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1155C>T; p.P385P; 6:166158468-166158468	skin	malignant_melanoma	Substitution - coding silent
c.875G>A; p.S292N; 6:166162476-166162476	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1293G>A; p.S431S; 6:166158330-166158330	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1263C>T; p.G421G; 6:166158360-166158360	skin	malignant_melanoma	Substitution - coding silent
c.1078C>T; p.P360S; 6:166158545-166158545	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.378C>A; p.H126Q; 6:166166685-166166685	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1231G>A; p.V411M; 6:166158392-166158392	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.506G>A; p.R169Q; 6:166165806-166165806	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.505C>T; p.R169*; 6:166165807-166165807	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.330G>A; p.V110V; 6:166166733-166166733	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1142C>A; p.A381E; 6:166158481-166158481	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.784C>T; p.P262S; 6:166162567-166162567	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.784C>T; p.P262S; 6:166162567-166162567	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.784C>T; p.P262S; 6:166162567-166162567	skin	malignant_melanoma	Substitution - Missense
c.581C>A; p.A194E; 6:166165731-166165731	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.282C>T; p.F94F; 6:166166781-166166781	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1204G>A; p.E402K; 6:166158419-166158419	skin	malignant_melanoma	Substitution - Missense
c.1204G>A; p.E402K; 6:166158419-166158419	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.894C>A; p.N298K; 6:166162457-166162457	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.611C>G; p.T204R; 6:166164857-166164857	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1119C>A; p.A373A; 6:166158504-166158504	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1119C>A; p.A373A; 6:166158504-166158504	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.79G>A; p.E27K; 6:166167513-166167513	skin	malignant_melanoma	Substitution - Missense
c.669-1G>T; p.?; 6:166164667-166164667	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.79G>A; p.E27K; 6:166167513-166167513	liver	carcinoma	Substitution - Missense
c.79G>A; p.E27K; 6:166167513-166167513	liver	carcinoma	Substitution - Missense
c.1250C>T; p.A417V; 6:166158373-166158373	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.343C>A; p.P115T; 6:166166720-166166720	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.980C>T; p.A327V; 6:166160891-166160891	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.699C>A; p.P233P; 6:166164636-166164636	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.472-1G>A; p.?; 6:166165841-166165841	endometrium	carcinoma; endometrioid_carcinoma	Unknown

The somatic mutations from COSMIC database