Entrez Gene

Basic Information
Gene ID	6786
Name	STIM1

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.1755G>A; p.A585A; 11:4091495-4091495	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1505G>A; p.R502H; 11:4086507-4086507	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.497+3C>T; p.?; 11:4055640-4055640	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.1313G>C; p.G438A; 11:4083337-4083337	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1927C>T; p.R643C; 11:4091667-4091667	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1080A>G; p.Q360Q; 11:4082294-4082294	liver	carcinoma	Substitution - coding silent
c.957G>A; p.E319E; 11:4074667-4074667	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1080A>G; p.Q360Q; 11:4082294-4082294	breast	carcinoma	Substitution - coding silent
c.1347A>T; p.S449S; 11:4083371-4083371	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1347A>T; p.S449S; 11:4083371-4083371	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1006G>T; p.E336*; 11:4082220-4082220	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.792-2A>G; p.?; 11:4074500-4074500	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.1082A>G; p.Y361C; 11:4082296-4082296	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1529T>G; p.L510R; 11:4086531-4086531	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.196G>A; p.E66K; 11:3967608-3967608	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.60C>G; p.G20G; 11:3856330-3856330	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1270C>T; p.R424W; 11:4083294-4083294	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.732G>T; p.M244I; 11:4070144-4070144	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.13G>A; p.V5I; 11:3856283-3856283	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1558G>A; p.D520N; 11:4091298-4091298	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.994G>A; p.E332K; 11:4082208-4082208	skin	malignant_melanoma	Substitution - Missense
c.227A>G; p.D76G; 11:3967639-3967639	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.895C>T; p.R299W; 11:4074605-4074605	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1205T>G; p.L402R; 11:4082949-4082949	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.226G>C; p.D76H; 11:3967638-3967638	liver	carcinoma	Substitution - Missense
c.136G>A; p.A46T; 11:3856406-3856406	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2030A>G; p.K677R; 11:4091770-4091770	pancreas	NS	Substitution - Missense
c.776A>G; p.H259R; 11:4070188-4070188	breast	carcinoma	Substitution - Missense
c.1507C>T; p.L503L; 11:4086509-4086509	skin	malignant_melanoma	Substitution - coding silent
c.1597G>T; p.V533L; 11:4091337-4091337	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1498C>T; p.R500W; 11:4086500-4086500	skin	malignant_melanoma	Substitution - Missense
c.1317C>T; p.F439F; 11:4083341-4083341	skin	malignant_melanoma	Substitution - coding silent
c.1371C>G; p.D457E; 11:4083395-4083395	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1499G>A; p.R500Q; 11:4086501-4086501	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1049G>T; p.W350L; 11:4082263-4082263	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1252G>T; p.E418*; 11:4083276-4083276	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1222A>C; p.K408Q; 11:4082966-4082966	skin	malignant_melanoma	Substitution - Missense
c.1928G>A; p.R643H; 11:4091668-4091668	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.112G>A; p.A38T; 11:3856382-3856382	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.246T>C; p.D82D; 11:3967658-3967658	prostate	carcinoma	Substitution - coding silent
c.1928G>A; p.R643H; 11:4091668-4091668	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1562C>T; p.S521L; 11:4091302-4091302	skin	malignant_melanoma	Substitution - Missense
c.1562C>T; p.S521L; 11:4091302-4091302	skin	malignant_melanoma	Substitution - Missense
c.1589G>A; p.R530H; 11:4091329-4091329	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.62A>G; p.Q21R; 11:3856332-3856332	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1541+2T>C; p.?; 11:4086545-4086545	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.115_116insA; p.N39fs*3; 11:3856385-3856386	stomach	carcinoma; intestinal_adenocarcinoma	Insertion - Frameshift
c.78T>C; p.S26S; 11:3856348-3856348	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1185C>G; p.H395Q; 11:4082929-4082929	liver	carcinoma	Substitution - Missense
c.1185C>G; p.H395Q; 11:4082929-4082929	liver	carcinoma	Substitution - Missense
c.114C>G; p.A38A; 11:3856384-3856384	bone; tibia	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1962T>A; p.A654A; 11:4091702-4091702	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.849A>G; p.E283E; 11:4074559-4074559	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.874C>T; p.L292F; 11:4074584-4074584	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1141G>T; p.E381*; 11:4082885-4082885	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1154A>C; p.K385T; 11:4082898-4082898	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1267T>C; p.L423L; 11:4083291-4083291	liver	carcinoma	Substitution - coding silent
c.1186G>A; p.V396M; 11:4082930-4082930	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1856C>T; p.P619L; 11:4091596-4091596	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1563G>A; p.S521S; 11:4091303-4091303	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.215A>G; p.H72R; 11:3967627-3967627	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.711C>T; p.S237S; 11:4070123-4070123	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1054C>A; p.Q352K; 11:4082268-4082268	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; NK-T_cell_lymphoma	Substitution - Missense
c.164T>A; p.L55Q; 11:3967576-3967576	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1521G>T; p.Q507H; 11:4086523-4086523	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1634A>G; p.D545G; 11:4091374-4091374	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.259G>C; p.E87Q; 11:3967671-3967671	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.275T>C; p.L92P; 11:4023877-4023877	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.612C>T; p.L204L; 11:4059395-4059395	skin	malignant_melanoma	Substitution - coding silent
c.1537C>T; p.Q513*; 11:4086539-4086539	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.651G>T; p.V217V; 11:4070063-4070063	prostate	carcinoma	Substitution - coding silent
c.651G>T; p.V217V; 11:4070063-4070063	prostate	carcinoma	Substitution - coding silent
c.1318C>T; p.Q440*; 11:4083342-4083342	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.248T>C; p.V83A; 11:3967660-3967660	skin; extremity	malignant_melanoma	Substitution - Missense
c.943A>C; p.K315Q; 11:4074653-4074653	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.250G>A; p.D84N; 11:3967662-3967662	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.187C>G; p.L63V; 11:3967599-3967599	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1440G>C; p.M480I; 11:4083464-4083464	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.1844G>A; p.R615H; 11:4091584-4091584	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1635C>T; p.D545D; 11:4091375-4091375	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.726G>T; p.K242N; 11:4070138-4070138	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.832G>T; p.E278*; 11:4074542-4074542	skin	malignant_melanoma	Substitution - Nonsense
c.1150A>C; p.K384Q; 11:4082894-4082894	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1691A>C; p.H564P; 11:4091431-4091431	breast	carcinoma	Substitution - Missense
c.574C>T; p.L192L; 11:4059357-4059357	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.938G>A; p.R313H; 11:4074648-4074648	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1976G>T; p.G659V; 11:4091716-4091716	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.1050G>A; p.W350*; 11:4082264-4082264	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.792-9delC; p.?; 11:4074493-4074493	liver	carcinoma	Unknown
c.1625G>A; p.R542H; 11:4091365-4091365	breast	carcinoma	Substitution - Missense
c.1625G>A; p.R542H; 11:4091365-4091365	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.1939C>T; p.L647L; 11:4091679-4091679	breast	carcinoma	Substitution - coding silent
c.1786C>T; p.L596L; 11:4091526-4091526	skin	malignant_melanoma	Substitution - coding silent
c.1305C>T; p.I435I; 11:4083329-4083329	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1223A>C; p.K408T; 11:4082967-4082967	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1254G>A; p.E418E; 11:4083278-4083278	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1300G>A; p.E434K; 11:4083324-4083324	breast	carcinoma	Substitution - Missense
c.834G>A; p.E278E; 11:4074544-4074544	skin	malignant_melanoma	Substitution - coding silent
c.2000C>G; p.S667C; 11:4091740-4091740	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1702C>T; p.L568L; 11:4091442-4091442	skin	malignant_melanoma	Substitution - coding silent
c.1028C>T; p.A343V; 11:4082242-4082242	skin	malignant_melanoma	Substitution - Missense
c.1512G>A; p.T504T; 11:4086514-4086514	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1474T>C; p.S492P; 11:4083498-4083498	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.703C>T; p.R235C; 11:4070115-4070115	central_nervous_system; brainstem	glioma; astrocytoma_Grade_II	Substitution - Missense
c.154G>A; p.D52N; 11:3967566-3967566	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.154G>A; p.D52N; 11:3967566-3967566	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.240T>A; p.N80K; 11:3967652-3967652	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.244G>A; p.D82N; 11:3967656-3967656	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1550C>T; p.T517I; 11:4091290-4091290	skin	malignant_melanoma	Substitution - Missense
c.1889T>C; p.V630A; 11:4091629-4091629	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1183C>T; p.H395Y; 11:4082927-4082927	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.93G>A; p.A31A; 11:3856363-3856363	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent

The somatic mutations from COSMIC database