Entrez Gene

Basic Information
Gene ID	6696
Name	SPP1

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.116C>T; p.A39V; 4:87980068-87980068	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.487G>T; p.V163L; 4:87981745-87981745	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.901C>T; p.R301C; 4:87982852-87982852	pituitary; craniopharyngeal_duct	craniopharyngioma; adamantinomatous	Substitution - Missense
c.901C>T; p.R301C; 4:87982852-87982852	skin; extremity	malignant_melanoma	Substitution - Missense
c.901C>T; p.R301C; 4:87982852-87982852	skin	malignant_melanoma	Substitution - Missense
c.901C>T; p.R301C; 4:87982852-87982852	skin	malignant_melanoma	Substitution - Missense
c.616C>T; p.P206S; 4:87982567-87982567	skin	malignant_melanoma	Substitution - Missense
c.119T>C; p.V40A; 4:87980071-87980071	breast	carcinoma	Substitution - Missense
c.46G>T; p.A16S; 4:87976941-87976941	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.747A>C; p.K249N; 4:87982698-87982698	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.530C>T; p.P177L; 4:87981788-87981788	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.65C>G; p.A22G; 4:87977069-87977069	prostate	carcinoma	Substitution - Missense
c.784G>C; p.D262H; 4:87982735-87982735	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.450C>T; p.V150V; 4:87981708-87981708	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.774C>A; p.S258S; 4:87982725-87982725	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.211C>A; p.Q71K; 4:87980429-87980429	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.757G>A; p.E253K; 4:87982708-87982708	skin	malignant_melanoma	Substitution - Missense
c.294C>A; p.D98E; 4:87981552-87981552	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.172C>T; p.Q58*; 4:87980124-87980124	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.429C>T; p.T143T; 4:87981687-87981687	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.703G>T; p.A235S; 4:87982654-87982654	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.822C>A; p.H274Q; 4:87982773-87982773	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.274G>T; p.D92Y; 4:87981532-87981532	urinary_tract; bladder	carcinoma	Substitution - Missense
c.750C>T; p.A250A; 4:87982701-87982701	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.409C>T; p.P137S; 4:87981667-87981667	skin	malignant_melanoma	Substitution - Missense
c.750C>T; p.A250A; 4:87982701-87982701	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.904A>G; p.I302V; 4:87982855-87982855	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.470A>G; p.D157G; 4:87981728-87981728	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.320A>C; p.D107A; 4:87981578-87981578	breast	carcinoma	Substitution - Missense
c.474C>T; p.G158G; 4:87981732-87981732	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.255G>A; p.M85I; 4:87981513-87981513	skin	malignant_melanoma	Substitution - Missense
c.518A>C; p.K173T; 4:87981776-87981776	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.584G>A; p.S195N; 4:87982535-87982535	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.84G>T; p.E28D; 4:87977088-87977088	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.873T>A; p.S291R; 4:87982824-87982824	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.887A>C; p.K296T; 4:87982838-87982838	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.475C>T; p.R159*; 4:87981733-87981733	skin	malignant_melanoma	Substitution - Nonsense
c.409C>A; p.P137T; 4:87981667-87981667	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.160C>A; p.L54I; 4:87980112-87980112	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.282T>C; p.D94D; 4:87981540-87981540	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.282T>C; p.D94D; 4:87981540-87981540	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.686A>G; p.Q229R; 4:87982637-87982637	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.109C>T; p.P37S; 4:87980061-87980061	central_nervous_system; brain	glioma	Substitution - Missense
c.584G>T; p.S195I; 4:87982535-87982535	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.657C>T; p.S219S; 4:87982608-87982608	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.831A>T; p.E277D; 4:87982782-87982782	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.241A>C; p.S81R; 4:87981499-87981499	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.524G>A; p.R175H; 4:87981782-87981782	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.685C>A; p.Q229K; 4:87982636-87982636	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.651G>A; p.W217*; 4:87982602-87982602	skin	malignant_melanoma	Substitution - Nonsense
c.638C>T; p.A213V; 4:87982589-87982589	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.541-7G>C; p.?; 4:87982485-87982485	NS	NS	Unknown
c.256G>A; p.D86N; 4:87981514-87981514	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.318C>T; p.N106N; 4:87981576-87981576	skin	malignant_melanoma	Substitution - coding silent
c.318C>T; p.N106N; 4:87981576-87981576	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.318C>T; p.N106N; 4:87981576-87981576	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.503G>T; p.R168M; 4:87981761-87981761	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.488T>C; p.V163A; 4:87981746-87981746	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.523C>T; p.R175C; 4:87981781-87981781	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.523C>T; p.R175C; 4:87981781-87981781	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.716G>T; p.S239I; 4:87982667-87982667	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.261T>A; p.D87E; 4:87981519-87981519	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.825C>T; p.S275S; 4:87982776-87982776	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.793_794insA; p.L266fs*7; 4:87982744-87982745	lung	carcinoma; small_cell_carcinoma	Insertion - Frameshift
c.598G>A; p.G200S; 4:87982549-87982549	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.414G>A; p.T138T; 4:87981672-87981672	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.237C>T; p.N79N; 4:87981495-87981495	breast	carcinoma	Substitution - coding silent

The somatic mutations from COSMIC database