Entrez Gene

Basic Information
Gene ID	654
Name	BMP6

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.450C>T; p.D150D; 6:7727405-7727405	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.395C>T; p.A132V; 6:7727350-7727350	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.117C>G; p.A39A; 6:7727072-7727072	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.117C>G; p.A39A; 6:7727072-7727072	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.745G>A; p.E249K; 6:7845220-7845220	skin	malignant_melanoma	Substitution - Missense
c.328C>G; p.Q110E; 6:7727283-7727283	liver	carcinoma	Substitution - Missense
c.795G>A; p.G265G; 6:7845270-7845270	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1410C>T; p.P470P; 6:7880211-7880211	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1410C>T; p.P470P; 6:7880211-7880211	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.736C>T; p.P246S; 6:7845211-7845211	skin	malignant_melanoma	Substitution - Missense
c.736C>T; p.P246S; 6:7845211-7845211	skin	malignant_melanoma	Substitution - Missense
c.736C>T; p.P246S; 6:7845211-7845211	skin	malignant_melanoma	Substitution - Missense
c.589G>A; p.A197T; 6:7727544-7727544	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.756G>A; p.T252T; 6:7845231-7845231	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.932C>T; p.T311M; 6:7861525-7861525	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.357G>T; p.L119L; 6:7727312-7727312	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.335_337delAGC; p.Q118delQ; 6:7727290-7727292	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - In frame
c.1153C>T; p.R385C; 6:7862447-7862447	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.861C>T; p.D287D; 6:7861454-7861454	breast	carcinoma	Substitution - coding silent
c.520C>T; p.P174S; 6:7727475-7727475	ovary	other; neoplasm	Substitution - Missense
c.989G>T; p.S330I; 6:7861582-7861582	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.255G>A; p.S85S; 6:7727210-7727210	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.180G>A; p.P60P; 6:7727135-7727135	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1185G>A; p.A395A; 6:7862479-7862479	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.381G>T; p.G127G; 6:7727336-7727336	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.503C>T; p.S168L; 6:7727458-7727458	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.381G>T; p.G127G; 6:7727336-7727336	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.543G>A; p.P181P; 6:7727498-7727498	central_nervous_system; brain	glioma	Substitution - coding silent
c.933G>A; p.T311T; 6:7861526-7861526	skin	malignant_melanoma	Substitution - coding silent
c.1416T>C; p.Y472Y; 6:7880217-7880217	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.691C>T; p.R231C; 6:7845166-7845166	skin	malignant_melanoma	Substitution - Missense
c.748G>A; p.V250M; 6:7845223-7845223	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.293G>A; p.G98D; 6:7727248-7727248	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.925G>A; p.D309N; 6:7861518-7861518	skin	malignant_melanoma	Substitution - Missense
c.679G>A; p.E227K; 6:7845154-7845154	skin; acral	malignant_melanoma	Substitution - Missense
c.1371C>A; p.N457K; 6:7880080-7880080	skin	malignant_melanoma	Substitution - Missense
c.1437G>A; p.A479A; 6:7880238-7880238	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1437G>A; p.A479A; 6:7880238-7880238	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1086C>A; p.F362L; 6:7862380-7862380	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.557G>T; p.S186I; 6:7727512-7727512	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1232C>T; p.A411V; 6:7879101-7879101	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.331G>C; p.E111Q; 6:7727286-7727286	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.400C>G; p.L134V; 6:7727355-7727355	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1109T>C; p.V370A; 6:7862403-7862403	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.364G>A; p.G122R; 6:7727319-7727319	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.287T>C; p.L96P; 6:7727242-7727242	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.1108G>A; p.V370M; 6:7862402-7862402	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.562C>T; p.L188L; 6:7727517-7727517	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.392C>T; p.S131F; 6:7727347-7727347	breast	carcinoma	Substitution - Missense
c.630C>T; p.N210N; 6:7727585-7727585	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.516G>A; p.R172R; 6:7727471-7727471	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.281G>A; p.R94Q; 6:7727236-7727236	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.794G>A; p.G265E; 6:7845269-7845269	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.794G>A; p.G265E; 6:7845269-7845269	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.353_355delAGC; p.Q118delQ; 6:7727308-7727310	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Deletion - In frame
c.1139G>A; p.R380H; 6:7862433-7862433	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1051G>A; p.G351S; 6:7862345-7862345	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.551G>A; p.R184H; 6:7727506-7727506	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1028C>A; p.A343D; 6:7862322-7862322	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1028C>A; p.A343D; 6:7862322-7862322	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1141C>T; p.R381*; 6:7862435-7862435	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Nonsense
c.703C>T; p.H235Y; 6:7845178-7845178	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.671A>G; p.Y224C; 6:7845146-7845146	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.353A>T; p.Q118L; 6:7727308-7727308	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.353A>T; p.Q118L; 6:7727308-7727308	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.353A>T; p.Q118L; 6:7727308-7727308	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.353A>T; p.Q118L; 6:7727308-7727308	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.623T>C; p.F208S; 6:7727578-7727578	skin	malignant_melanoma	Substitution - Missense
c.1066C>G; p.Q356E; 6:7862360-7862360	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.688C>T; p.P230S; 6:7845163-7845163	skin	malignant_melanoma	Substitution - Missense
c.1454C>T; p.A485V; 6:7880255-7880255	skin	malignant_melanoma	Substitution - Missense
c.1461G>A; p.S487S; 6:7880262-7880262	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.664G>A; p.V222M; 6:7727619-7727619	skin	malignant_melanoma	Substitution - Missense
c.1377G>A; p.A459A; 6:7880086-7880086	skin	malignant_melanoma	Substitution - coding silent
c.1160G>C; p.R387P; 6:7862454-7862454	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.442G>A; p.D148N; 6:7727397-7727397	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1185G>C; p.A395A; 6:7862479-7862479	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1374C>T; p.H458H; 6:7880083-7880083	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.760G>A; p.A254T; 6:7845235-7845235	prostate	adenoma	Substitution - Missense
c.574T>C; p.S192P; 6:7727529-7727529	liver	carcinoma	Substitution - Missense
c.1536C>T; p.C512C; 6:7880337-7880337	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.574T>C; p.S192P; 6:7727529-7727529	liver	carcinoma	Substitution - Missense
c.1227A>C; p.K409N; 6:7879096-7879096	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.750G>A; p.V250V; 6:7845225-7845225	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1205-1G>T; p.?; 6:7879073-7879073	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.704A>G; p.H235R; 6:7845179-7845179	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1405A>G; p.N469D; 6:7880206-7880206	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.704A>G; p.H235R; 6:7845179-7845179	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1177G>A; p.D393N; 6:7862471-7862471	skin	malignant_melanoma	Substitution - Missense
c.1488T>A; p.N496K; 6:7880289-7880289	liver	carcinoma	Substitution - Missense
c.1521A>G; p.V507V; 6:7880322-7880322	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1445A>C; p.K482T; 6:7880246-7880246	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1040T>G; p.V347G; 6:7862334-7862334	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1136G>A; p.R379Q; 6:7862430-7862430	thyroid	carcinoma	Substitution - Missense
c.643G>A; p.V215I; 6:7727598-7727598	skin	malignant_melanoma	Substitution - Missense
c.1028_1029CC>TT; p.A343V; 6:7862322-7862323	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1154G>A; p.R385H; 6:7862448-7862448	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.254C>T; p.S85L; 6:7727209-7727209	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.717G>A; p.K239K; 6:7845192-7845192	liver	carcinoma	Substitution - coding silent
c.717G>A; p.K239K; 6:7845192-7845192	liver	carcinoma	Substitution - coding silent
c.522G>A; p.P174P; 6:7727477-7727477	ovary	other; neoplasm	Substitution - coding silent
c.1028C>T; p.A343V; 6:7862322-7862322	skin	malignant_melanoma	Substitution - Missense
c.665-7C>A; p.?; 6:7845133-7845133	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1038G>T; p.L346L; 6:7862332-7862332	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.692G>A; p.R231H; 6:7845167-7845167	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.692G>A; p.R231H; 6:7845167-7845167	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.692G>A; p.R231H; 6:7845167-7845167	breast	carcinoma	Substitution - Missense
c.1140C>A; p.R380R; 6:7862434-7862434	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1173C>T; p.S391S; 6:7862467-7862467	skin	malignant_melanoma	Substitution - coding silent
c.1042G>T; p.G348C; 6:7862336-7862336	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1113C>T; p.R371R; 6:7862407-7862407	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1024C>T; p.R342*; 6:7862318-7862318	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.304C>T; p.P102S; 6:7727259-7727259	liver	carcinoma	Substitution - Missense
c.304C>T; p.P102S; 6:7727259-7727259	liver	carcinoma	Substitution - Missense
c.594C>A; p.S198S; 6:7727549-7727549	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1122G>C; p.R374S; 6:7862416-7862416	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1351G>A; p.A451T; 6:7880060-7880060	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.463G>A; p.G155R; 6:7727418-7727418	skin	malignant_melanoma	Substitution - Missense
c.1394T>C; p.V465A; 6:7880195-7880195	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.306G>A; p.P102P; 6:7727261-7727261	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1142G>A; p.R381Q; 6:7862436-7862436	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.169C>T; p.P57S; 6:7727124-7727124	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.832C>G; p.Q278E; 6:7845307-7845307	breast	carcinoma	Substitution - Missense
c.164A>C; p.Q55P; 6:7727119-7727119	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.408G>A; p.M136I; 6:7727363-7727363	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1460C>T; p.S487L; 6:7880261-7880261	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1059C>T; p.Y353Y; 6:7862353-7862353	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1059C>T; p.Y353Y; 6:7862353-7862353	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.798delT; p.F267fs*31; 6:7845273-7845273	lung	carcinoma; small_cell_carcinoma	Deletion - Frameshift
c.415C>T; p.L139L; 6:7727370-7727370	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.83G>A; p.R28Q; 6:7727038-7727038	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.83G>A; p.R28Q; 6:7727038-7727038	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1427C>T; p.P476L; 6:7880228-7880228	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1404G>A; p.M468I; 6:7880205-7880205	skin	malignant_melanoma	Substitution - Missense
c.83G>A; p.R28Q; 6:7727038-7727038	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1427C>T; p.P476L; 6:7880228-7880228	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.83G>A; p.R28Q; 6:7727038-7727038	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.83G>A; p.R28Q; 6:7727038-7727038	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense

The somatic mutations from COSMIC database