Entrez Gene

Basic Information
Gene ID	6423
Name	SFRP2

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.829C>T; p.Q277*; 4:153781510-153781510	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.471C>T; p.S157S; 4:153788365-153788365	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.380C>T; p.P127L; 4:153788456-153788456	skin	malignant_melanoma	Substitution - Missense
c.523T>C; p.C175R; 4:153785924-153785924	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.704C>T; p.S235L; 4:153781635-153781635	skin	malignant_melanoma	Substitution - Missense
c.704C>T; p.S235L; 4:153781635-153781635	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.431G>A; p.R144H; 4:153788405-153788405	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.431G>A; p.R144H; 4:153788405-153788405	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.474C>T; p.S158S; 4:153788362-153788362	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.583+2T>A; p.?; 4:153785862-153785862	lung; right_upper_lobe	carcinoma; adenocarcinoma	Unknown
c.745G>T; p.E249*; 4:153781594-153781594	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.883T>G; p.C295G; 4:153781456-153781456	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.237G>A; p.W79*; 4:153788599-153788599	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.55C>A; p.L19M; 4:153788781-153788781	thyroid	other; neoplasm	Substitution - Missense
c.676G>A; p.G226S; 4:153781663-153781663	thyroid	carcinoma; anaplastic_carcinoma	Substitution - Missense
c.437C>T; p.P146L; 4:153788399-153788399	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.118T>A; p.C40S; 4:153788718-153788718	urinary_tract; bladder	carcinoma	Substitution - Missense
c.188T>A; p.L63Q; 4:153788648-153788648	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.752A>G; p.N251S; 4:153781587-153781587	skin	malignant_melanoma	Substitution - Missense
c.499G>A; p.E167K; 4:153788337-153788337	skin	malignant_melanoma	Substitution - Missense
c.524G>A; p.C175Y; 4:153785923-153785923	prostate	carcinoma	Substitution - Missense
c.625G>C; p.D209H; 4:153781714-153781714	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.625G>C; p.D209H; 4:153781714-153781714	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.866G>T; p.S289I; 4:153781473-153781473	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.306C>T; p.V102V; 4:153788530-153788530	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.176G>A; p.R59Q; 4:153788660-153788660	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.134C>T; p.A45V; 4:153788702-153788702	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.134C>T; p.A45V; 4:153788702-153788702	thyroid	other; neoplasm	Substitution - Missense
c.835G>A; p.G279R; 4:153781504-153781504	skin	malignant_melanoma	Substitution - Missense
c.338C>T; p.P113L; 4:153788498-153788498	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.348G>A; p.S116S; 4:153788488-153788488	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.199G>A; p.E67K; 4:153788637-153788637	skin	malignant_melanoma	Substitution - Missense
c.863G>T; p.R288L; 4:153781476-153781476	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.863G>T; p.R288L; 4:153781476-153781476	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.70G>A; p.G24R; 4:153788766-153788766	pancreas	carcinoma	Substitution - Missense
c.762C>T; p.N254N; 4:153781577-153781577	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.99C>A; p.F33L; 4:153788737-153788737	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.754G>A; p.D252N; 4:153781585-153781585	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.75C>T; p.L25L; 4:153788761-153788761	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.376G>A; p.A126T; 4:153788460-153788460	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.297C>T; p.F99F; 4:153788539-153788539	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.297C>T; p.F99F; 4:153788539-153788539	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.816G>C; p.S272S; 4:153781523-153781523	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.775G>A; p.V259I; 4:153781564-153781564	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.67C>T; p.R23C; 4:153788769-153788769	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.690G>A; p.R230R; 4:153781649-153781649	skin	malignant_melanoma	Substitution - coding silent
c.816G>A; p.S272S; 4:153781523-153781523	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.816G>A; p.S272S; 4:153781523-153781523	large_intestine; rectum	NS	Substitution - coding silent
c.816G>A; p.S272S; 4:153781523-153781523	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.590A>C; p.K197T; 4:153781749-153781749	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.661A>G; p.I221V; 4:153781678-153781678	skin	malignant_melanoma	Substitution - Missense
c.776T>C; p.V259A; 4:153781563-153781563	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.606G>C; p.E202D; 4:153781733-153781733	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.776T>C; p.V259A; 4:153781563-153781563	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.776T>C; p.V259A; 4:153781563-153781563	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.132T>G; p.P44P; 4:153788704-153788704	thyroid	other; neoplasm	Substitution - coding silent
c.133G>T; p.A45S; 4:153788703-153788703	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.675C>T; p.N225N; 4:153781664-153781664	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.763G>A; p.A255T; 4:153781576-153781576	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.571A>G; p.K191E; 4:153785876-153785876	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.763G>A; p.A255T; 4:153781576-153781576	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.563C>T; p.T188M; 4:153785884-153785884	pancreas	carcinoma	Substitution - Missense
c.763G>A; p.A255T; 4:153781576-153781576	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.429C>T; p.D143D; 4:153788407-153788407	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.66G>A; p.A22A; 4:153788770-153788770	thyroid	other; neoplasm	Substitution - coding silent
c.21G>C; p.S7S; 4:153788815-153788815	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.753C>T; p.N251N; 4:153781586-153781586	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.241C>T; p.P81S; 4:153788595-153788595	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.486G>C; p.L162L; 4:153788350-153788350	thyroid	other; neoplasm	Substitution - coding silent
c.147delG; p.C50fs*20; 4:153788689-153788689	endometrium	carcinoma; endometrioid_carcinoma	Deletion - Frameshift
c.647C>T; p.T216I; 4:153781692-153781692	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.588G>A; p.L196L; 4:153781751-153781751	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.853C>T; p.R285C; 4:153781486-153781486	prostate	carcinoma	Substitution - Missense
c.463delC; p.L155fs*31; 4:153788373-153788373	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.773_784del12; p.L258_G261delLVMG; 4:153781555-153781566	skin; scalp	malignant_melanoma	Deletion - In frame
c.389C>T; p.S130F; 4:153788447-153788447	skin	malignant_melanoma	Substitution - Missense
c.20_21insGCT; p.L11_F12insL; 4:153788815-153788816	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Insertion - In frame
c.175C>T; p.R59W; 4:153788661-153788661	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.738C>T; p.T246T; 4:153781601-153781601	skin	malignant_melanoma	Substitution - coding silent
c.705G>A; p.S235S; 4:153781634-153781634	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.622C>T; p.R208*; 4:153781717-153781717	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.540T>G; p.D180E; 4:153785907-153785907	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.540T>G; p.D180E; 4:153785907-153785907	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.683C>T; p.S228F; 4:153781656-153781656	skin	malignant_melanoma	Substitution - Missense
c.866G>A; p.S289N; 4:153781473-153781473	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.727T>A; p.L243M; 4:153781612-153781612	skin	malignant_melanoma	Substitution - Missense
c.745G>A; p.E249K; 4:153781594-153781594	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.248T>C; p.V83A; 4:153788588-153788588	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.32_33insGCT; p.L11_F12insL; 4:153788803-153788804	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Insertion - In frame
c.815C>A; p.S272*; 4:153781524-153781524	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.325G>A; p.E109K; 4:153788511-153788511	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.325G>A; p.E109K; 4:153788511-153788511	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.78C>T; p.F26F; 4:153788758-153788758	thyroid	other; neoplasm	Substitution - coding silent
c.211G>C; p.E71Q; 4:153788625-153788625	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.396C>T; p.F132F; 4:153788440-153788440	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.823C>T; p.R275W; 4:153781516-153781516	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.814T>A; p.S272T; 4:153781525-153781525	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.298G>A; p.A100T; 4:153788538-153788538	central_nervous_system; brain	glioma	Substitution - Missense
c.150C>T; p.C50C; 4:153788686-153788686	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.871C>T; p.R291C; 4:153781468-153781468	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.829C>G; p.Q277E; 4:153781510-153781510	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense

The somatic mutations from COSMIC database