Entrez Gene

Basic Information
Gene ID	634
Name	CEACAM1

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.1051A>T; p.N351Y; 19:42519143-42519143	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.673C>T; p.R225C; 19:42521954-42521954	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1153C>A; p.P385T; 19:42519041-42519041	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.673C>T; p.R225C; 19:42521954-42521954	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1376+2T>A; p.?; 19:42512348-42512348	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Unknown
c.1479T>C; p.Y493Y; 19:42509211-42509211	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1468G>A; p.E490K; 19:42509222-42509222	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1479T>C; p.Y493Y; 19:42509211-42509211	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1468G>A; p.E490K; 19:42509222-42509222	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1376+2T>A; p.?; 19:42512348-42512348	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Unknown
c.1576C>T; p.Q526*; 19:42509114-42509114	kidney	other; neoplasm	Substitution - Nonsense
c.259C>T; p.Q87*; 19:42527206-42527206	ovary	carcinoma; adenocarcinoma	Substitution - Nonsense
c.50G>T; p.G17V; 19:42528325-42528325	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.754_755GG>AA; p.G252K; 19:42521470-42521471	skin	malignant_melanoma	Substitution - Missense
c.798T>A; p.P266P; 19:42521427-42521427	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.246T>A; p.Y82*; 19:42527219-42527219	pancreas	carcinoma	Substitution - Nonsense
c.452G>T; p.S151I; 19:42522175-42522175	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.289G>A; p.G97S; 19:42527176-42527176	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.352G>T; p.G118*; 19:42527113-42527113	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Nonsense
c.1536C>T; p.S512S; 19:42509154-42509154	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.372C>A; p.V124V; 19:42527093-42527093	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.317C>T; p.S106F; 19:42527148-42527148	skin	malignant_melanoma	Substitution - Missense
c.1222G>A; p.D408N; 19:42518972-42518972	skin	malignant_melanoma	Substitution - Missense
c.1044C>T; p.C348C; 19:42519150-42519150	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1178C>T; p.T393M; 19:42519016-42519016	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.224G>A; p.G75D; 19:42527241-42527241	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.922T>G; p.C308G; 19:42521303-42521303	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.350C>T; p.T117I; 19:42527115-42527115	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.350C>T; p.T117I; 19:42527115-42527115	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.541A>T; p.N181Y; 19:42522086-42522086	skin	malignant_melanoma	Substitution - Missense
c.892A>C; p.T298P; 19:42521333-42521333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.892A>C; p.T298P; 19:42521333-42521333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.892A>C; p.T298P; 19:42521333-42521333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.892A>C; p.T298P; 19:42521333-42521333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.892A>C; p.T298P; 19:42521333-42521333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.892A>C; p.T298P; 19:42521333-42521333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.892A>C; p.T298P; 19:42521333-42521333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1488G>A; p.L496L; 19:42509202-42509202	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1383C>T; p.S461S; 19:42511622-42511622	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1383C>T; p.S461S; 19:42511622-42511622	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.183A>T; p.Q61H; 19:42527282-42527282	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.183A>T; p.Q61H; 19:42527282-42527282	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1404G>A; p.E468E; 19:42511601-42511601	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.84G>A; p.W28*; 19:42527381-42527381	NS	malignant_melanoma	Substitution - Nonsense
c.84G>A; p.W28*; 19:42527381-42527381	NS	malignant_melanoma	Substitution - Nonsense
c.292C>T; p.R98*; 19:42527173-42527173	skin	malignant_melanoma	Substitution - Nonsense
c.688A>C; p.T230P; 19:42521939-42521939	breast	carcinoma	Substitution - Missense
c.621G>A; p.R207R; 19:42522006-42522006	skin	malignant_melanoma	Substitution - coding silent
c.1096C>T; p.L366F; 19:42519098-42519098	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1049C>T; p.T350I; 19:42519145-42519145	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1247-1G>C; p.?; 19:42512480-42512480	lung	carcinoma; adenocarcinoma	Unknown
c.1362C>T; p.F454F; 19:42512364-42512364	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.438G>T; p.K146N; 19:42522189-42522189	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.900C>T; p.H300H; 19:42521325-42521325	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1142T>A; p.L381H; 19:42519052-42519052	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.958+3A>C; p.?; 19:42521264-42521264	ovary	other; neoplasm	Unknown
c.1432C>A; p.Q478K; 19:42510918-42510918	pancreas	carcinoma	Substitution - Missense
c.90G>A; p.P30P; 19:42527375-42527375	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.202T>G; p.Y68D; 19:42527263-42527263	breast	carcinoma	Substitution - Missense
c.143G>A; p.G48E; 19:42527322-42527322	skin	malignant_melanoma	Substitution - Missense
c.385C>A; p.L129I; 19:42527080-42527080	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.29G>C; p.R10T; 19:42528346-42528346	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1031_1032delTG; p.V344fs*8; 19:42519162-42519163	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.502G>A; p.E168K; 19:42522125-42522125	skin	malignant_melanoma	Substitution - Missense
c.49G>A; p.G17R; 19:42528326-42528326	skin	malignant_melanoma	Substitution - Missense
c.270C>T; p.T90T; 19:42527195-42527195	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1069A>C; p.I357L; 19:42519125-42519125	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.515A>G; p.Q172R; 19:42522112-42522112	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.64G>T; p.A22S; 19:42528311-42528311	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1384G>A; p.D462N; 19:42511621-42511621	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.687C>T; p.V229V; 19:42521940-42521940	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.293G>A; p.R98Q; 19:42527172-42527172	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.11T>G; p.L4R; 19:42528364-42528364	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1239C>T; p.N413N; 19:42518955-42518955	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.859C>T; p.P287S; 19:42521366-42521366	soft_tissue; blood_vessel	angiosarcoma	Substitution - Missense
c.893C>T; p.T298I; 19:42521332-42521332	prostate	carcinoma	Substitution - Missense
c.1221C>T; p.S407S; 19:42518973-42518973	breast	carcinoma	Substitution - coding silent
c.898C>A; p.H300N; 19:42521327-42521327	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1376+5G>C; p.?; 19:42512345-42512345	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.407G>A; p.G136E; 19:42527058-42527058	skin	malignant_melanoma	Substitution - Missense
c.280G>A; p.A94T; 19:42527185-42527185	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.444C>T; p.S148S; 19:42522183-42522183	skin	malignant_melanoma	Substitution - coding silent
c.426G>A; p.P142P; 19:42522201-42522201	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.491C>T; p.A164V; 19:42522136-42522136	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.353G>A; p.G118E; 19:42527112-42527112	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.352G>A; p.G118R; 19:42527113-42527113	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1032G>A; p.V344V; 19:42519162-42519162	skin	malignant_melanoma	Substitution - coding silent
c.1032G>A; p.V344V; 19:42519162-42519162	breast	carcinoma	Substitution - coding silent
c.646G>A; p.E216K; 19:42521981-42521981	skin; scalp	malignant_melanoma	Substitution - Missense
c.922T>C; p.C308R; 19:42521303-42521303	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.674G>T; p.R225L; 19:42521953-42521953	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.922T>C; p.C308R; 19:42521303-42521303	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1394A>G; p.D465G; 19:42511611-42511611	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.922T>C; p.C308R; 19:42521303-42521303	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.669G>A; p.A223A; 19:42521958-42521958	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.669G>A; p.A223A; 19:42521958-42521958	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1128G>T; p.Q376H; 19:42519066-42519066	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.906T>C; p.N302N; 19:42521319-42521319	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_B_cell_leukaemia	Substitution - coding silent
c.254G>A; p.G85E; 19:42527211-42527211	skin	malignant_melanoma	Substitution - Missense
c.576G>A; p.Q192Q; 19:42522051-42522051	skin	malignant_melanoma	Substitution - coding silent
c.571C>T; p.L191L; 19:42522056-42522056	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.693G>A; p.L231L; 19:42521934-42521934	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1130G>A; p.G377D; 19:42519064-42519064	skin	malignant_melanoma	Substitution - Missense
c.210G>C; p.G70G; 19:42527255-42527255	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - coding silent
c.210G>C; p.G70G; 19:42527255-42527255	thyroid	other; neoplasm	Substitution - coding silent
c.1464G>T; p.M488I; 19:42509226-42509226	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.558G>T; p.P186P; 19:42522069-42522069	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent

The somatic mutations from COSMIC database