Entrez Gene

Basic Information
Gene ID	6050
Name	RNH1

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.190C>T; p.R64C; 11:500566-500566	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.104T>C; p.L35P; 11:500652-500652	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.660C>G; p.C220W; 11:498888-498888	ovary	carcinoma	Substitution - Missense
c.134G>A; p.C45Y; 11:500622-500622	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.363C>T; p.S121S; 11:499909-499909	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.557G>A; p.G186D; 11:499072-499072	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.570G>A; p.L190L; 11:499059-499059	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1071C>T; p.G357G; 11:498027-498027	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1071C>T; p.G357G; 11:498027-498027	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1072G>A; p.V358M; 11:498026-498026	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1202G>C; p.R401P; 11:494979-494979	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.216C>T; p.G72G; 11:500540-500540	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.383C>T; p.A128V; 11:499889-499889	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.130C>A; p.R44R; 11:500626-500626	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.415G>T; p.D139Y; 11:499857-499857	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.298_299insG; p.A100fs*79; 11:499973-499974	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.575A>G; p.Q192R; 11:499054-499054	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1281C>T; p.C427C; 11:494900-494900	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.563G>A; p.R188H; 11:499066-499066	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.563G>A; p.R188H; 11:499066-499066	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.27C>T; p.D9D; 11:502136-502136	breast	carcinoma	Substitution - coding silent
c.934G>T; p.G312C; 11:498479-498479	liver	carcinoma	Substitution - Missense
c.1349T>C; p.L450P; 11:494728-494728	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.950C>T; p.S317L; 11:498463-498463	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.707G>T; p.S236I; 11:498841-498841	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1354_1356delAAG; p.K452delK; 11:494721-494723	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - In frame
c.623G>T; p.S208I; 11:498925-498925	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.464C>T; p.S155L; 11:499165-499165	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.628G>A; p.G210S; 11:498920-498920	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1341G>A; p.L447L; 11:494736-494736	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1267C>T; p.R423W; 11:494914-494914	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.498C>G; p.L166L; 11:499131-499131	breast	carcinoma	Substitution - coding silent
c.1007T>A; p.V336E; 11:498091-498091	skin	malignant_melanoma	Substitution - Missense
c.1351G>C; p.E451Q; 11:494726-494726	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.64G>A; p.E22K; 11:502099-502099	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.966C>A; p.S322S; 11:498132-498132	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.19_33del15; p.S7_Q11delSLDIQ; 11:502130-502144	endometrium	carcinoma; endometrioid_carcinoma	Deletion - In frame
c.988T>C; p.C330R; 11:498110-498110	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.249delC; p.S84fs*7; 11:500507-500507	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.329G>A; p.R110H; 11:499943-499943	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.804C>T; p.I268I; 11:498609-498609	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.67C>T; p.L23F; 11:502096-502096	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.131G>A; p.R44Q; 11:500625-500625	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1273C>T; p.P425S; 11:494908-494908	prostate	carcinoma	Substitution - Missense
c.64G>C; p.E22Q; 11:502099-502099	skin	malignant_melanoma	Substitution - Missense
c.1239C>G; p.A413A; 11:494942-494942	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.694C>T; p.L232L; 11:498854-498854	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.11A>T; p.D4V; 11:502152-502152	liver	carcinoma	Substitution - Missense
c.11A>T; p.D4V; 11:502152-502152	liver	carcinoma	Substitution - Missense
c.609G>A; p.A203A; 11:499020-499020	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.981C>T; p.A327A; 11:498117-498117	pancreas	carcinoma	Substitution - coding silent
c.776G>T; p.R259M; 11:498772-498772	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1369C>A; p.L457M; 11:494708-494708	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.122C>T; p.T41M; 11:500634-500634	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.361A>G; p.S121G; 11:499911-499911	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1368C>T; p.S456S; 11:494709-494709	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1228C>T; p.L410L; 11:494953-494953	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.84G>A; p.Q28Q; 11:502079-502079	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.838C>A; p.L280I; 11:498575-498575	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.31C>T; p.Q11*; 11:502132-502132	skin	malignant_melanoma	Substitution - Nonsense

The somatic mutations from COSMIC database