Entrez Gene

Basic Information
Gene ID	59343
Name	SENP2

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.649C>T; p.R217*; 3:185609277-185609277	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1582G>A; p.E528K; 3:185624053-185624053	skin	malignant_melanoma	Substitution - Missense
c.1708-8C>A; p.?; 3:185629774-185629774	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1277G>T; p.R426I; 3:185619333-185619333	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.117A>G; p.T39T; 3:185590129-185590129	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.416G>A; p.R139Q; 3:185600822-185600822	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.416G>A; p.R139Q; 3:185600822-185600822	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1150C>T; p.P384S; 3:185617519-185617519	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.902C>A; p.T301K; 3:185613377-185613377	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.902C>A; p.T301K; 3:185613377-185613377	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.596G>A; p.R199H; 3:185606476-185606476	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1273G>A; p.E425K; 3:185619329-185619329	thyroid	other; neoplasm	Substitution - Missense
c.300G>A; p.S100S; 3:185598966-185598966	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.601C>T; p.H201Y; 3:185606481-185606481	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1540G>A; p.D514N; 3:185624011-185624011	skin	malignant_melanoma	Substitution - Missense
c.1757A>C; p.Q586P; 3:185629831-185629831	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.764delG; p.E257fs*29; 3:185611692-185611692	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1149C>T; p.G383G; 3:185617518-185617518	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - coding silent
c.1389C>G; p.L463L; 3:185619445-185619445	breast	carcinoma	Substitution - coding silent
c.1345delG; p.G450fs*5; 3:185619401-185619401	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1112A>C; p.D371A; 3:185617481-185617481	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.869+1G>A; p.?; 3:185612659-185612659	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.1331C>A; p.P444H; 3:185619387-185619387	skin	malignant_melanoma	Substitution - Missense
c.1175C>T; p.A392V; 3:185617544-185617544	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.299C>G; p.S100W; 3:185598965-185598965	skin	malignant_melanoma	Substitution - Missense
c.299C>G; p.S100W; 3:185598965-185598965	skin	malignant_melanoma	Substitution - Missense
c.261T>G; p.N87K; 3:185598515-185598515	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1558A>T; p.R520*; 3:185624029-185624029	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.733A>G; p.S245G; 3:185611661-185611661	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.328T>C; p.S110P; 3:185598994-185598994	skin	malignant_melanoma	Substitution - Missense
c.1163T>C; p.I388T; 3:185617532-185617532	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.650G>A; p.R217Q; 3:185609278-185609278	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.977C>T; p.S326L; 3:185614607-185614607	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1382T>C; p.V461A; 3:185619438-185619438	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.146G>T; p.R49I; 3:185590158-185590158	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.836G>A; p.R279K; 3:185612625-185612625	skin	malignant_melanoma	Substitution - Missense
c.1445T>A; p.V482E; 3:185619501-185619501	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.368C>A; p.S123Y; 3:185600774-185600774	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1499A>G; p.K500R; 3:185621878-185621878	skin	malignant_melanoma	Substitution - Missense
c.768G>A; p.G256G; 3:185611696-185611696	liver	carcinoma	Substitution - coding silent
c.204C>T; p.S68S; 3:185598458-185598458	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.839G>C; p.G280A; 3:185612628-185612628	liver	carcinoma	Substitution - Missense
c.1574A>G; p.N525S; 3:185624045-185624045	liver	carcinoma	Substitution - Missense
c.1574A>G; p.N525S; 3:185624045-185624045	liver	carcinoma	Substitution - Missense
c.1053G>T; p.K351N; 3:185614683-185614683	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1090G>A; p.D364N; 3:185614720-185614720	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1090G>A; p.D364N; 3:185614720-185614720	breast	carcinoma	Substitution - Missense
c.497G>A; p.R166H; 3:185606377-185606377	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.370C>T; p.P124S; 3:185600776-185600776	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.840A>C; p.G280G; 3:185612629-185612629	skin	malignant_melanoma	Substitution - coding silent
c.299C>T; p.S100L; 3:185598965-185598965	skin	malignant_melanoma	Substitution - Missense
c.32C>A; p.T11N; 3:185586445-185586445	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1754A>T; p.H585L; 3:185629828-185629828	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1362G>A; p.V454V; 3:185619418-185619418	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1468T>G; p.C490G; 3:185621847-185621847	skin	malignant_melanoma	Substitution - Missense
c.870-3T>G; p.?; 3:185613342-185613342	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.1709A>G; p.H570R; 3:185629783-185629783	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1350T>C; p.G450G; 3:185619406-185619406	skin	malignant_melanoma	Substitution - coding silent
c.1707G>C; p.Q569H; 3:185626393-185626393	kidney	other; neoplasm	Substitution - Missense
c.1389C>A; p.L463L; 3:185619445-185619445	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1446+1G>A; p.?; 3:185619503-185619503	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Unknown
c.1446+1G>A; p.?; 3:185619503-185619503	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Unknown
c.1389C>A; p.L463L; 3:185619445-185619445	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.427C>T; p.R143C; 3:185600833-185600833	oesophagus	carcinoma	Substitution - Missense
c.1640A>G; p.D547G; 3:185626326-185626326	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.665G>A; p.R222Q; 3:185609293-185609293	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1005C>A; p.S335R; 3:185614635-185614635	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.988C>T; p.R330C; 3:185614618-185614618	skin	malignant_melanoma	Substitution - Missense
c.988C>T; p.R330C; 3:185614618-185614618	liver	carcinoma	Substitution - Missense
c.988C>T; p.R330C; 3:185614618-185614618	skin; extremity	malignant_melanoma	Substitution - Missense
c.84G>A; p.K28K; 3:185586497-185586497	breast	carcinoma	Substitution - coding silent
c.414C>A; p.T138T; 3:185600820-185600820	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.640G>C; p.E214Q; 3:185609268-185609268	lung	carcinoma; bronchioloalveolar_adenocarcinoma	Substitution - Missense
c.631G>T; p.E211*; 3:185609259-185609259	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.352A>G; p.K118E; 3:185599018-185599018	central_nervous_system; brain	glioma	Substitution - Missense
c.1272G>A; p.V424V; 3:185619328-185619328	thyroid	other; neoplasm	Substitution - coding silent
c.870-6C>T; p.?; 3:185613339-185613339	skin; leg	malignant_melanoma	Unknown
c.870-6C>T; p.?; 3:185613339-185613339	skin; leg	malignant_melanoma	Unknown
c.898G>A; p.E300K; 3:185613373-185613373	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.898G>A; p.E300K; 3:185613373-185613373	urinary_tract; bladder	carcinoma	Substitution - Missense
c.413C>T; p.T138I; 3:185600819-185600819	skin	malignant_melanoma	Substitution - Missense
c.1559G>T; p.R520I; 3:185624030-185624030	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.802T>C; p.F268L; 3:185611730-185611730	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1559G>T; p.R520I; 3:185624030-185624030	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1731G>C; p.K577N; 3:185629805-185629805	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense

The somatic mutations from COSMIC database