Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

59

Name

ACTA2

The somatic mutations from COSMIC database

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.367C>G; p.Q123E; 10:88943799-88943799

breastcarcinoma; HER-positive_carcinomaSubstitution - Missense

c.220G>T; p.E74*; 10:88947296-88947296

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.696C>T; p.A232A; 10:88939619-88939619

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.496C>G; p.P166A; 10:88941349-88941349

breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.496C>G; p.P166A; 10:88941349-88941349

breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.836C>A; p.T279N; 10:88938215-88938215

urinary_tract; bladdercarcinomaSubstitution - Missense

c.844A>G; p.N282D; 10:88938207-88938207

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.653T>A; p.L218Q; 10:88939662-88939662

skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.327G>T; p.E109D; 10:88943839-88943839

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.327G>T; p.E109D; 10:88943839-88943839

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.246C>T; p.D82D; 10:88947270-88947270

central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.983A>C; p.K328T; 10:88938068-88938068

oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.607G>A; p.V203I; 10:88941238-88941238

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.607G>A; p.V203I; 10:88941238-88941238

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.607G>A; p.V203I; 10:88941238-88941238

stomachadenocarcinomaSubstitution - Missense

c.607G>A; p.V203I; 10:88941238-88941238

breastcarcinomaSubstitution - Missense

c.727G>A; p.E243K; 10:88939588-88939588

central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.289C>T; p.R97C; 10:88943877-88943877

kidneycarcinoma; renal_cell_carcinomaSubstitution - Missense

c.107T>C; p.I36T; 10:88948824-88948824

central_nervous_system; braingliomaSubstitution - Missense

c.290G>A; p.R97H; 10:88943876-88943876

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1001C>T; p.P334L; 10:88935356-88935356

skinmalignant_melanomaSubstitution - Missense

c.324G>A; p.T108T; 10:88943842-88943842

large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1006G>A; p.E336K; 10:88935351-88935351

urinary_tract; bladdercarcinomaSubstitution - Missense

c.174C>T; p.D58D; 10:88947342-88947342

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.657T>C; p.C219C; 10:88939658-88939658

pancreascarcinomaSubstitution - coding silent

c.115C>T; p.R39C; 10:88948816-88948816

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.447C>T; p.R149R; 10:88941792-88941792

stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.808+6C>G; p.?; 10:88939501-88939501

skin; legmalignant_melanoma; nodularUnknown

c.64G>A; p.G22S; 10:88948867-88948867

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.535C>T; p.R179C; 10:88941310-88941310

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.832G>A; p.E278K; 10:88938219-88938219

skinmalignant_melanomaSubstitution - Missense

c.175G>A; p.E59K; 10:88947341-88947341

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.470C>T; p.S157F; 10:88941375-88941375

urinary_tract; bladdercarcinomaSubstitution - Missense

c.349A>G; p.N117D; 10:88943817-88943817

skinmalignant_melanomaSubstitution - Missense

c.726C>T; p.Y242Y; 10:88939589-88939589

endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1032T>C; p.G344G; 10:88935325-88935325

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.742C>T; p.Q248*; 10:88939573-88939573

haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Nonsense

c.737A>G; p.D246G; 10:88939578-88939578

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.554G>A; p.R185Q; 10:88941291-88941291

breastcarcinomaSubstitution - Missense

c.783G>A; p.E261E; 10:88939532-88939532

stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.740G>A; p.G247E; 10:88939575-88939575

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.130-3_130-2insT; p.?; 10:88947388-88947389

skinmalignant_melanomaUnknown

c.1005G>A; p.P335P; 10:88935352-88935352

haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.1005G>A; p.P335P; 10:88935352-88935352

haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.288T>A; p.L96L; 10:88943878-88943878

ovaryother; neoplasmSubstitution - coding silent

c.767G>A; p.R256H; 10:88939548-88939548

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.92C>T; p.A31V; 10:88948839-88948839

ovaryother; neoplasmSubstitution - Missense

c.13G>C; p.E5Q; 10:88948918-88948918

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1073G>A; p.W358*; 10:88935284-88935284

skinmalignant_melanomaSubstitution - Nonsense

c.941G>A; p.R314Q; 10:88938110-88938110

skinmalignant_melanomaSubstitution - Missense

c.479G>C; p.G160A; 10:88941366-88941366

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.940C>T; p.R314*; 10:88938111-88938111

large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.116G>A; p.R39H; 10:88948815-88948815

breastcarcinomaSubstitution - Missense

c.116G>A; p.R39H; 10:88948815-88948815

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.386T>C; p.F129S; 10:88941853-88941853

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.911delG; p.G304fs*19; 10:88938140-88938140

large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.950A>C; p.K317T; 10:88938101-88938101

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.78C>T; p.D26D; 10:88948853-88948853

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.606C>T; p.F202F; 10:88941239-88941239

large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1092C>T; p.Y364Y; 10:88935265-88935265

endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.633C>A; p.V211V; 10:88939682-88939682

lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.345G>T; p.K115N; 10:88943821-88943821

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.369A>C; p.Q123H; 10:88943797-88943797

stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense


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