Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

5653

Name

KLK6

The somatic mutations from COSMIC database

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.358G>A; p.E120K; 19:50963389-50963389

 breastcarcinomaSubstitution - Missense

c.707G>A; p.W236*; 19:50959192-50959192

 skinmalignant_melanomaSubstitution - Nonsense

c.233G>A; p.R78Q; 19:50963514-50963514

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.131A>G; p.H44R; 19:50967235-50967235

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.611G>A; p.G204E; 19:50959288-50959288

 skin; trunkmalignant_melanoma; nodularSubstitution - Missense

c.422_423TG>GT; p.L141>?; 19:50963324-50963325

 lungcarcinoma; small_cell_carcinomaComplex

c.92C>T; p.T31I; 19:50967274-50967274

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.76G>A; p.G26R; 19:50967290-50967290

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.76G>A; p.G26R; 19:50967290-50967290

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.195delA; p.K65fs*29; 19:50967171-50967171

 stomachcarcinoma; intestinal_adenocarcinomaDeletion - Frameshift

c.702G>A; p.T234T; 19:50959197-50959197

 skinmalignant_melanomaSubstitution - coding silent

c.331C>T; p.R111C; 19:50963416-50963416

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.331C>T; p.R111C; 19:50963416-50963416

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.126G>A; p.S42S; 19:50967240-50967240

 skinmalignant_melanomaSubstitution - coding silent

c.265G>C; p.V89L; 19:50963482-50963482

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.83G>A; p.C28Y; 19:50967283-50967283

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.274G>A; p.A92T; 19:50963473-50963473

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.634T>G; p.S212A; 19:50959265-50959265

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.453C>T; p.F151F; 19:50961873-50961873

 skinmalignant_melanomaSubstitution - coding silent

c.453C>T; p.F151F; 19:50961873-50961873

 skinmalignant_melanomaSubstitution - coding silent

c.85G>A; p.D29N; 19:50967281-50967281

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.168G>T; p.W56C; 19:50967198-50967198

 adrenal_gland; adrenal_glandadrenal_cortical_carcinoma; functioningSubstitution - Missense

c.387G>A; p.R129R; 19:50963360-50963360

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.270C>T; p.V90V; 19:50963477-50963477

 livercarcinomaSubstitution - coding silent

c.600G>A; p.P200P; 19:50959299-50959299

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.40+2T>C; p.?; 19:50968063-50968063

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.85G>T; p.D29Y; 19:50967281-50967281

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.411C>T; p.S137S; 19:50963336-50963336

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.81C>T; p.P27P; 19:50967285-50967285

 breastcarcinomaSubstitution - coding silent

c.332G>A; p.R111H; 19:50963415-50963415

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.332G>A; p.R111H; 19:50963415-50963415

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.332G>A; p.R111H; 19:50963415-50963415

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.626G>A; p.G209D; 19:50959273-50959273

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.541T>G; p.L181V; 19:50961785-50961785

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.663G>A; p.K221K; 19:50959236-50959236

 skin; armmalignant_melanomaSubstitution - coding silent

c.356C>T; p.S119F; 19:50963391-50963391

 skinmalignant_melanomaSubstitution - Missense

c.210C>A; p.V70V; 19:50963537-50963537

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.184C>T; p.H62Y; 19:50967182-50967182

 skinmalignant_melanomaSubstitution - Missense

c.26G>C; p.S9T; 19:50968079-50968079

 kidneyother; neoplasmSubstitution - Missense

c.521G>A; p.G174D; 19:50961805-50961805

 skinmalignant_melanomaSubstitution - Missense

c.687C>T; p.N229N; 19:50959212-50959212

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.599C>T; p.P200L; 19:50959300-50959300

 livercarcinomaSubstitution - Missense

c.421C>A; p.L141M; 19:50963326-50963326

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.599C>T; p.P200L; 19:50959300-50959300

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.666G>A; p.E222E; 19:50959233-50959233

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.599C>T; p.P200L; 19:50959300-50959300

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.599C>T; p.P200L; 19:50959300-50959300

 livercarcinomaSubstitution - Missense

c.599C>T; p.P200L; 19:50959300-50959300

 skinmalignant_melanomaSubstitution - Missense

c.695G>T; p.R232I; 19:50959204-50959204

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.125C>T; p.S42L; 19:50967241-50967241

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.340C>T; p.R114C; 19:50963407-50963407

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.340C>T; p.R114C; 19:50963407-50963407

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.486G>C; p.L162L; 19:50961840-50961840

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.182C>G; p.A61G; 19:50967184-50967184

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.115C>T; p.L39F; 19:50967251-50967251

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.601C>T; p.L201L; 19:50959298-50959298

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.325C>T; p.L109L; 19:50963422-50963422

 skinmalignant_melanomaSubstitution - coding silent

c.295G>A; p.D99N; 19:50963452-50963452

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.321C>T; p.I107I; 19:50963426-50963426

 skin; trunkmalignant_melanoma; nodularSubstitution - coding silent

c.321C>T; p.I107I; 19:50963426-50963426

 skinmalignant_melanomaSubstitution - coding silent

c.40+1G>T; p.?; 19:50968064-50968064

 lungcarcinoma; squamous_cell_carcinomaUnknown

c.454C>T; p.P152S; 19:50961872-50961872

 skinmalignant_melanomaSubstitution - Missense

c.494G>A; p.R165H; 19:50961832-50961832

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.381G>A; p.L127L; 19:50963366-50963366

 central_nervous_system; braingliomaSubstitution - coding silent

c.566_567GG>AA; p.G189E; 19:50961759-50961760

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.472G>C; p.A158P; 19:50961854-50961854

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.143G>T; p.G48V; 19:50967223-50967223

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.366C>T; p.I122I; 19:50963381-50963381

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.213C>T; p.F71F; 19:50963534-50963534

 skinmalignant_melanomaSubstitution - coding silent

c.324G>C; p.M108I; 19:50963423-50963423

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.588T>C; p.D196D; 19:50959311-50959311

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.106C>T; p.Q36*; 19:50967260-50967260

 skinmalignant_melanomaSubstitution - Nonsense

c.635C>T; p.S212L; 19:50959264-50959264

 skin; extremitymalignant_melanomaSubstitution - Missense

c.623G>A; p.R208Q; 19:50959276-50959276

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

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