Entrez Gene

Basic Information
Gene ID	5176
Name	SERPINF1

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.341G>A; p.S114N; 17:1771086-1771086	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1146C>T; p.L382L; 17:1777335-1777335	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.215C>T; p.T72M; 17:1769982-1769982	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.200G>A; p.R67Q; 17:1769967-1769967	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.543C>A; p.N181K; 17:1771975-1771975	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.787-1G>T; p.?; 17:1776531-1776531	breast	carcinoma	Unknown
c.776T>G; p.L259R; 17:1775190-1775190	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.232G>A; p.V78M; 17:1769999-1769999	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1215_1216CC>GA; p.A405>?; 17:1777404-1777405	large_intestine; colon	carcinoma; adenocarcinoma	Complex
c.963T>C; p.Y321Y; 17:1776708-1776708	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.963T>C; p.Y321Y; 17:1776708-1776708	thyroid	other; neoplasm	Substitution - coding silent
c.963T>C; p.Y321Y; 17:1776708-1776708	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.6G>T; p.Q2H; 17:1766916-1766916	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.455C>T; p.S152F; 17:1771887-1771887	ovary	other; neoplasm	Substitution - Missense
c.816G>A; p.M272I; 17:1776561-1776561	skin	malignant_melanoma	Substitution - Missense
c.975C>G; p.V325V; 17:1776720-1776720	central_nervous_system; brain	atypical_teratoid-rhabdoid_tumour	Substitution - coding silent
c.1221C>G; p.L407L; 17:1777410-1777410	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.262G>A; p.A88T; 17:1770029-1770029	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.454T>A; p.S152T; 17:1771886-1771886	ovary	other; neoplasm	Substitution - Missense
c.199C>A; p.R67R; 17:1769966-1769966	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.875G>A; p.S292N; 17:1776620-1776620	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.440-2A>C; p.?; 17:1771870-1771870	lung	carcinoma; adenocarcinoma	Unknown
c.1107G>A; p.A369A; 17:1777296-1777296	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.296G>A; p.R99Q; 17:1771041-1771041	skin	malignant_melanoma	Substitution - Missense
c.296G>A; p.R99Q; 17:1771041-1771041	breast	carcinoma	Substitution - Missense
c.616C>A; p.L206I; 17:1772048-1772048	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.970G>A; p.E324K; 17:1776715-1776715	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.913C>G; p.L305V; 17:1776658-1776658	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.225G>A; p.T75T; 17:1769992-1769992	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.852G>T; p.Q284H; 17:1776597-1776597	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.288G>T; p.A96A; 17:1771033-1771033	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.288G>T; p.A96A; 17:1771033-1771033	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.392delC; p.Q133fs*18; 17:1771137-1771137	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.390T>C; p.T130T; 17:1771135-1771135	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.390T>C; p.T130T; 17:1771135-1771135	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.390T>C; p.T130T; 17:1771135-1771135	breast	carcinoma	Substitution - coding silent
c.390T>C; p.T130T; 17:1771135-1771135	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.291G>A; p.E97E; 17:1771036-1771036	skin	malignant_melanoma	Substitution - coding silent
c.643+6C>T; p.?; 17:1772081-1772081	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.643+6C>T; p.?; 17:1772081-1772081	pancreas	carcinoma; adenocarcinoma	Unknown
c.451A>C; p.K151Q; 17:1771883-1771883	breast	carcinoma	Substitution - Missense
c.879C>T; p.L293L; 17:1776624-1776624	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.500G>A; p.R167K; 17:1771932-1771932	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.644-1G>A; p.?; 17:1775057-1775057	skin	malignant_melanoma	Unknown
c.265C>T; p.L89F; 17:1770032-1770032	skin	malignant_melanoma	Substitution - Missense
c.218G>A; p.S73N; 17:1769985-1769985	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.718A>T; p.R240W; 17:1775132-1775132	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.336G>A; p.L112L; 17:1771081-1771081	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.441G>A; p.K147K; 17:1771873-1771873	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.113C>G; p.A38G; 17:1769880-1769880	skin	malignant_melanoma	Substitution - Missense
c.287C>T; p.A96V; 17:1771032-1771032	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.287C>T; p.A96V; 17:1771032-1771032	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.292C>A; p.Q98K; 17:1771037-1771037	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1087G>A; p.E363K; 17:1777276-1777276	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1213G>A; p.A405T; 17:1777402-1777402	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.748G>C; p.V250L; 17:1775162-1775162	bone; pelvis	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.929C>T; p.A310V; 17:1776674-1776674	liver	carcinoma	Substitution - Missense
c.1176G>T; p.Q392H; 17:1777365-1777365	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.537G>T; p.E179D; 17:1771969-1771969	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.284G>A; p.G95E; 17:1771029-1771029	skin; ear	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1251C>G; p.G417G; 17:1777440-1777440	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.115C>A; p.L39M; 17:1769882-1769882	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.115C>A; p.L39M; 17:1769882-1769882	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.633G>A; p.A211A; 17:1772065-1772065	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.399G>T; p.Q133H; 17:1771144-1771144	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.964G>A; p.E322K; 17:1776709-1776709	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense

The somatic mutations from COSMIC database