Entrez Gene

Basic Information
Gene ID	5029
Name	P2RY2

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.483G>A; p.V161V; 11:73234642-73234642	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1082G>C; p.R361P; 11:73235241-73235241	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1000C>T; p.R334C; 11:73235159-73235159	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.762C>T; p.F254F; 11:73234921-73234921	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.762C>T; p.F254F; 11:73234921-73234921	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.85G>A; p.E29K; 11:73234244-73234244	skin	malignant_melanoma	Substitution - Missense
c.248C>T; p.A83V; 11:73234407-73234407	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.248C>T; p.A83V; 11:73234407-73234407	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.283C>T; p.R95C; 11:73234442-73234442	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.283C>T; p.R95C; 11:73234442-73234442	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.321G>A; p.K107K; 11:73234480-73234480	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1081C>T; p.R361W; 11:73235240-73235240	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.571C>A; p.L191I; 11:73234730-73234730	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.571C>A; p.L191I; 11:73234730-73234730	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.400G>C; p.G134R; 11:73234559-73234559	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.419G>A; p.R140H; 11:73234578-73234578	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.227C>T; p.A76V; 11:73234386-73234386	skin	malignant_melanoma	Substitution - Missense
c.227C>T; p.A76V; 11:73234386-73234386	skin	malignant_melanoma	Substitution - Missense
c.334C>T; p.L112F; 11:73234493-73234493	skin	malignant_melanoma	Substitution - Missense
c.763G>A; p.A255T; 11:73234922-73234922	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.530G>A; p.R177H; 11:73234689-73234689	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.763G>A; p.A255T; 11:73234922-73234922	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.741C>T; p.I247I; 11:73234900-73234900	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.400G>A; p.G134S; 11:73234559-73234559	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.133G>A; p.V45M; 11:73234292-73234292	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.133G>A; p.V45M; 11:73234292-73234292	central_nervous_system; brain	glioma	Substitution - Missense
c.245A>G; p.Y82C; 11:73234404-73234404	oesophagus	carcinoma	Substitution - Missense
c.422C>T; p.S141F; 11:73234581-73234581	ovary	other; neoplasm	Substitution - Missense
c.422C>T; p.S141F; 11:73234581-73234581	ovary	other; neoplasm	Substitution - Missense
c.194G>A; p.W65*; 11:73234353-73234353	skin	malignant_melanoma	Substitution - Nonsense
c.454C>T; p.R152W; 11:73234613-73234613	liver	carcinoma	Substitution - Missense
c.454C>T; p.R152W; 11:73234613-73234613	liver	carcinoma	Substitution - Missense
c.497delC; p.V168fs*14; 11:73234656-73234656	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.636C>T; p.A212A; 11:73234795-73234795	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.635C>T; p.A212V; 11:73234794-73234794	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.333C>T; p.F111F; 11:73234492-73234492	skin	malignant_melanoma	Substitution - coding silent
c.801C>G; p.L267L; 11:73234960-73234960	breast	carcinoma	Substitution - coding silent
c.642C>T; p.I214I; 11:73234801-73234801	skin	malignant_melanoma	Substitution - coding silent
c.1104T>A; p.G368G; 11:73235263-73235263	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.846C>T; p.N282N; 11:73235005-73235005	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.733C>T; p.R245C; 11:73234892-73234892	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.316T>A; p.C106S; 11:73234475-73234475	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.622G>A; p.A208T; 11:73234781-73234781	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.742G>A; p.A248T; 11:73234901-73234901	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.392G>T; p.R131L; 11:73234551-73234551	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.392G>T; p.R131L; 11:73234551-73234551	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.392G>T; p.R131L; 11:73234551-73234551	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1085C>A; p.T362K; 11:73235244-73235244	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.20C>A; p.P7H; 11:73234179-73234179	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.499C>T; p.P167S; 11:73234658-73234658	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.201G>A; p.A67A; 11:73234360-73234360	central_nervous_system; brain	glioma	Substitution - coding silent
c.409C>T; p.R137*; 11:73234568-73234568	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.658C>T; p.L220F; 11:73234817-73234817	NS	malignant_melanoma	Substitution - Missense
c.413C>A; p.P138H; 11:73234572-73234572	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.413C>A; p.P138H; 11:73234572-73234572	large_intestine; colon	carcinoma	Substitution - Missense
c.413C>A; p.P138H; 11:73234572-73234572	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.280G>A; p.A94T; 11:73234439-73234439	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.975C>T; p.G325G; 11:73235134-73235134	skin	malignant_melanoma	Substitution - coding silent
c.637G>A; p.V213I; 11:73234796-73234796	bone; femur	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.447C>T; p.Y149Y; 11:73234606-73234606	thyroid	carcinoma	Substitution - coding silent
c.698C>T; p.S233L; 11:73234857-73234857	urinary_tract; bladder	carcinoma	Substitution - Missense
c.379A>T; p.I127F; 11:73234538-73234538	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.72G>T; p.R24S; 11:73234231-73234231	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.879G>A; p.P293P; 11:73235038-73235038	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.768C>G; p.L256L; 11:73234927-73234927	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.469G>A; p.V157M; 11:73234628-73234628	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.469G>A; p.V157M; 11:73234628-73234628	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.684A>G; p.P228P; 11:73234843-73234843	prostate	carcinoma	Substitution - coding silent
c.565C>G; p.P189A; 11:73234724-73234724	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.120C>T; p.Y40Y; 11:73234279-73234279	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.738C>T; p.T246T; 11:73234897-73234897	skin	malignant_melanoma	Substitution - coding silent
c.120C>T; p.Y40Y; 11:73234279-73234279	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.502G>A; p.V168M; 11:73234661-73234661	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.877C>T; p.P293S; 11:73235036-73235036	skin	malignant_melanoma	Substitution - Missense
c.702C>T; p.G234G; 11:73234861-73234861	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.814C>T; p.R272C; 11:73234973-73234973	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.859G>A; p.A287T; 11:73235018-73235018	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.181C>T; p.R61C; 11:73234340-73234340	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.169A>G; p.I57V; 11:73234328-73234328	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1028G>A; p.R343K; 11:73235187-73235187	skin	malignant_melanoma	Substitution - Missense
c.410G>A; p.R137Q; 11:73234569-73234569	skin; shoulder	malignant_melanoma	Substitution - Missense
c.423C>T; p.S141S; 11:73234582-73234582	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.423C>T; p.S141S; 11:73234582-73234582	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.674T>C; p.L225P; 11:73234833-73234833	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.283C>A; p.R95S; 11:73234442-73234442	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.621C>T; p.F207F; 11:73234780-73234780	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.501C>T; p.P167P; 11:73234660-73234660	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.501C>T; p.P167P; 11:73234660-73234660	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.596G>T; p.S199I; 11:73234755-73234755	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.230T>C; p.V77A; 11:73234389-73234389	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.329G>A; p.R110H; 11:73234488-73234488	ovary	other; neoplasm	Substitution - Missense
c.318C>A; p.C106*; 11:73234477-73234477	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.162G>A; p.A54A; 11:73234321-73234321	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.722G>T; p.R241L; 11:73234881-73234881	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.123C>T; p.G41G; 11:73234282-73234282	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.123C>T; p.G41G; 11:73234282-73234282	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.468C>T; p.A156A; 11:73234627-73234627	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.254C>T; p.S85F; 11:73234413-73234413	skin	malignant_melanoma	Substitution - Missense
c.847G>A; p.A283T; 11:73235006-73235006	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.571C>T; p.L191F; 11:73234730-73234730	skin	malignant_melanoma	Substitution - Missense
c.53G>A; p.G18E; 11:73234212-73234212	skin	malignant_melanoma	Substitution - Missense
c.428G>A; p.R143H; 11:73234587-73234587	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.561G>A; p.S187S; 11:73234720-73234720	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.92T>G; p.F31C; 11:73234251-73234251	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.943C>T; p.R315C; 11:73235102-73235102	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.936G>C; p.R312S; 11:73235095-73235095	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.690C>T; p.Y230Y; 11:73234849-73234849	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.690C>T; p.Y230Y; 11:73234849-73234849	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.464G>A; p.G155E; 11:73234623-73234623	skin	malignant_melanoma	Substitution - Missense
c.462C>T; p.A154A; 11:73234621-73234621	skin	malignant_melanoma	Substitution - coding silent
c.922C>T; p.L308L; 11:73235081-73235081	skin	malignant_melanoma	Substitution - coding silent
c.247G>A; p.A83T; 11:73234406-73234406	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.247G>A; p.A83T; 11:73234406-73234406	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.137C>T; p.P46L; 11:73234296-73234296	thyroid	other; neoplasm	Substitution - Missense
c.442C>G; p.R148G; 11:73234601-73234601	ovary	other; neoplasm	Substitution - Missense
c.428G>T; p.R143L; 11:73234587-73234587	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1004G>A; p.R335K; 11:73235163-73235163	breast	carcinoma	Substitution - Missense
c.623C>T; p.A208V; 11:73234782-73234782	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.816C>T; p.R272R; 11:73234975-73234975	thyroid	other; neoplasm	Substitution - coding silent
c.775C>T; p.L259L; 11:73234934-73234934	skin	malignant_melanoma	Substitution - coding silent
c.816C>T; p.R272R; 11:73234975-73234975	liver	carcinoma	Substitution - coding silent
c.816C>T; p.R272R; 11:73234975-73234975	thyroid	other; neoplasm	Substitution - coding silent
c.816C>T; p.R272R; 11:73234975-73234975	thyroid	other; neoplasm	Substitution - coding silent

The somatic mutations from COSMIC database