Entrez Gene

Basic Information
Gene ID	4854
Name	NOTCH3

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.3074C>A; p.P1025H; 19:15180749-15180749	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2330C>T; p.P777L; 19:15184986-15184986	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5089G>T; p.V1697L; 19:15170356-15170356	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5543G>A; p.R1848H; 19:15165911-15165911	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.6151C>T; p.P2051S; 19:15161477-15161477	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2953C>T; p.R985C; 19:15181002-15181002	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5799T>A; p.N1933K; 19:15165384-15165384	skin; neck	malignant_melanoma	Substitution - Missense
c.763G>A; p.V255I; 19:15191784-15191784	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5070C>G; p.H1690Q; 19:15170375-15170375	ovary	other; neoplasm	Substitution - Missense
c.6738C>A; p.T2246T; 19:15160890-15160890	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.5939C>T; p.A1980V; 19:15161689-15161689	liver	carcinoma	Substitution - Missense
c.1335G>A; p.T445T; 19:15189032-15189032	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3682G>A; p.G1228R; 19:15179061-15179061	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5028C>T; p.F1676F; 19:15170417-15170417	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.6786C>T; p.S2262S; 19:15160842-15160842	skin	malignant_melanoma	Substitution - coding silent
c.4781C>T; p.S1594L; 19:15170781-15170781	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.325C>T; p.P109S; 19:15192392-15192392	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3680G>A; p.G1227D; 19:15179063-15179063	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1669G>T; p.G557C; 19:15187276-15187276	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.973C>T; p.H325Y; 19:15191487-15191487	skin; nipple	malignant_melanoma	Substitution - Missense
c.605C>T; p.A202V; 19:15192034-15192034	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.213_214GG>AA; p.W71_V72>*; 19:15192503-15192504	skin; head_neck	carcinoma; squamous_cell_carcinoma	Complex - deletion inframe
c.5095C>G; p.Q1699E; 19:15170350-15170350	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.1130G>T; p.C377F; 19:15189335-15189335	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.5304G>T; p.L1768L; 19:15167307-15167307	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.5377C>T; p.L1793L; 19:15166077-15166077	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.5533C>A; p.L1845M; 19:15165921-15165921	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.5098G>T; p.D1700Y; 19:15170347-15170347	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4305C>T; p.R1435R; 19:15177623-15177623	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1690G>A; p.A564T; 19:15187255-15187255	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1690G>A; p.A564T; 19:15187255-15187255	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.5676C>T; p.I1892I; 19:15165507-15165507	skin	malignant_melanoma	Substitution - coding silent
c.6380A>T; p.Y2127F; 19:15161248-15161248	liver	carcinoma	Substitution - Missense
c.1132A>C; p.T378P; 19:15189333-15189333	breast	carcinoma	Substitution - Missense
c.5445C>T; p.D1815D; 19:15166009-15166009	breast	carcinoma	Substitution - coding silent
c.2044C>A; p.L682I; 19:15185587-15185587	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3149G>T; p.R1050L; 19:15180250-15180250	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.6076C>T; p.Q2026*; 19:15161552-15161552	breast	carcinoma	Substitution - Nonsense
c.1140T>C; p.P380P; 19:15189325-15189325	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1509G>T; p.T503T; 19:15187978-15187978	pancreas	carcinoma	Substitution - coding silent
c.3762A>T; p.P1254P; 19:15178898-15178898	thyroid	carcinoma	Substitution - coding silent
c.5145G>A; p.G1715G; 19:15170140-15170140	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.2331G>A; p.P777P; 19:15184985-15184985	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.5412G>A; p.E1804E; 19:15166042-15166042	skin	malignant_melanoma	Substitution - coding silent
c.6106C>T; p.P2036S; 19:15161522-15161522	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5840C>T; p.A1947V; 19:15162538-15162538	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.6945C>G; p.P2315P; 19:15160683-15160683	stomach	adenocarcinoma	Substitution - coding silent
c.2630C>A; p.P877H; 19:15181738-15181738	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4960C>T; p.L1654L; 19:15170485-15170485	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1366_1367insTC; p.C457fs*143; 19:15189000-15189001	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Insertion - Frameshift
c.687G>C; p.E229D; 19:15191860-15191860	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.687G>C; p.E229D; 19:15191860-15191860	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.5812C>T; p.L1938F; 19:15165371-15165371	skin	malignant_melanoma	Substitution - Missense
c.2985G>A; p.P995P; 19:15180970-15180970	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2652C>A; p.C884*; 19:15181716-15181716	liver	carcinoma	Substitution - Nonsense
c.5837C>T; p.A1946V; 19:15162541-15162541	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2652C>A; p.C884*; 19:15181716-15181716	liver	carcinoma; hepatocellular_carcinoma	Substitution - Nonsense
c.1752C>T; p.D584D; 19:15187193-15187193	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.2292C>T; p.V764V; 19:15185261-15185261	skin	malignant_melanoma	Substitution - coding silent
c.5941C>T; p.R1981C; 19:15161687-15161687	ovary	carcinoma; adenocarcinoma	Substitution - Missense
c.905G>A; p.C302Y; 19:15191555-15191555	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4531G>A; p.G1511S; 19:15174273-15174273	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2193G>C; p.Q731H; 19:15185360-15185360	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5763G>A; p.M1921I; 19:15165420-15165420	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.5723C>T; p.T1908M; 19:15165460-15165460	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5245C>T; p.Q1749*; 19:15167366-15167366	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.4431C>T; p.D1477D; 19:15174373-15174373	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2029A>C; p.N677H; 19:15185602-15185602	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2029A>C; p.N677H; 19:15185602-15185602	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3646G>A; p.A1216T; 19:15179097-15179097	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.5103G>A; p.A1701A; 19:15170342-15170342	breast	carcinoma	Substitution - coding silent
c.6877C>T; p.P2293S; 19:15160751-15160751	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5210C>T; p.P1737L; 19:15167401-15167401	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.5480A>T; p.Q1827L; 19:15165974-15165974	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3776G>A; p.G1259D; 19:15178884-15178884	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.5007C>T; p.R1669R; 19:15170438-15170438	liver	carcinoma	Substitution - coding silent
c.5007C>T; p.R1669R; 19:15170438-15170438	liver	carcinoma	Substitution - coding silent
c.5007C>T; p.R1669R; 19:15170438-15170438	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.2451C>T; p.P817P; 19:15184410-15184410	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.5261A>G; p.H1754R; 19:15167350-15167350	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1524G>A; p.V508V; 19:15187963-15187963	prostate	carcinoma	Substitution - coding silent
c.5683C>T; p.R1895C; 19:15165500-15165500	prostate	carcinoma	Substitution - Missense
c.4937T>G; p.L1646R; 19:15170508-15170508	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.488G>A; p.R163Q; 19:15192151-15192151	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2905C>T; p.R969W; 19:15181050-15181050	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.4766G>A; p.R1589Q; 19:15170796-15170796	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4734C>T; p.I1578I; 19:15174070-15174070	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1399G>A; p.E467K; 19:15188328-15188328	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6637G>A; p.A2213T; 19:15160991-15160991	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1399G>A; p.E467K; 19:15188328-15188328	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.6865G>T; p.A2289S; 19:15160763-15160763	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.984C>G; p.T328T; 19:15191476-15191476	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.894C>A; p.H298Q; 19:15191566-15191566	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3291delG; p.T1098fs*174; 19:15180108-15180108	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1067T>C; p.V356A; 19:15189398-15189398	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.3291delG; p.T1098fs*174; 19:15180108-15180108	NS	malignant_melanoma	Deletion - Frameshift
c.1886G>T; p.C629F; 19:15186943-15186943	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.136G>A; p.G46R; 19:15197561-15197561	skin	malignant_melanoma	Substitution - Missense
c.1084G>A; p.E362K; 19:15189381-15189381	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.165C>T; p.C55C; 19:15197532-15197532	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2203C>T; p.R735*; 19:15185350-15185350	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.6221C>T; p.P2074L; 19:15161407-15161407	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1084G>A; p.E362K; 19:15189381-15189381	urinary_tract; bladder	carcinoma	Substitution - Missense
c.6221C>T; p.P2074L; 19:15161407-15161407	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.4822G>A; p.A1608T; 19:15170740-15170740	breast	carcinoma	Substitution - Missense
c.6532C>T; p.P2178S; 19:15161096-15161096	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.5053G>A; p.D1685N; 19:15170392-15170392	skin	malignant_melanoma	Substitution - Missense
c.5074G>A; p.G1692S; 19:15170371-15170371	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6015C>G; p.D2005E; 19:15161613-15161613	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.3683G>A; p.G1228E; 19:15179060-15179060	skin	malignant_melanoma	Substitution - Missense
c.4690G>T; p.G1564C; 19:15174114-15174114	skin	malignant_melanoma	Substitution - Missense
c.4417A>T; p.K1473*; 19:15174387-15174387	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.308G>A; p.R103Q; 19:15192409-15192409	skin	malignant_melanoma	Substitution - Missense
c.1721A>G; p.Y574C; 19:15187224-15187224	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.6065G>A; p.R2022H; 19:15161563-15161563	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.308G>A; p.R103Q; 19:15192409-15192409	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5280C>G; p.I1760M; 19:15167331-15167331	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.4898C>T; p.P1633L; 19:15170547-15170547	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4898C>T; p.P1633L; 19:15170547-15170547	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3450A>G; p.P1150P; 19:15179374-15179374	liver	carcinoma	Substitution - coding silent
c.1490C>T; p.S497L; 19:15188237-15188237	oesophagus	carcinoma	Substitution - Missense
c.3450A>G; p.P1150P; 19:15179374-15179374	liver	carcinoma	Substitution - coding silent
c.5404delG; p.A1802fs*23; 19:15166050-15166050	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1490C>T; p.S497L; 19:15188237-15188237	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1341C>T; p.L447L; 19:15189026-15189026	central_nervous_system; brain	glioma	Substitution - coding silent
c.790C>A; p.P264T; 19:15191757-15191757	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.3795G>A; p.P1265P; 19:15178865-15178865	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1107T>C; p.N369N; 19:15189358-15189358	skin	malignant_melanoma	Substitution - coding silent
c.5089G>A; p.V1697M; 19:15170356-15170356	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2057G>T; p.G686V; 19:15185574-15185574	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.5089G>A; p.V1697M; 19:15170356-15170356	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1227G>T; p.V409V; 19:15189140-15189140	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2692C>A; p.P898T; 19:15181676-15181676	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2665G>A; p.D889N; 19:15181703-15181703	breast	carcinoma	Substitution - Missense
c.6201delC; p.K2069fs*16; 19:15161427-15161427	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1924G>A; p.D642N; 19:15186905-15186905	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5491C>G; p.L1831V; 19:15165963-15165963	central_nervous_system; brain	glioma	Substitution - Missense
c.6864_6865delTG; p.A2289fs*>33; 19:15160763-15160764	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.6864_6865delTG; p.A2289fs*>33; 19:15160763-15160764	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.1662C>T; p.C554C; 19:15187283-15187283	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.676C>T; p.P226S; 19:15191963-15191963	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6668C>T; p.A2223V; 19:15160960-15160960	thyroid	other; neoplasm	Substitution - Missense
c.6668C>T; p.A2223V; 19:15160960-15160960	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.6668C>T; p.A2223V; 19:15160960-15160960	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.660C>T; p.Y220Y; 19:15191979-15191979	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.6668C>T; p.A2223V; 19:15160960-15160960	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5595C>T; p.T1865T; 19:15165859-15165859	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.676C>T; p.P226S; 19:15191963-15191963	skin	malignant_melanoma	Substitution - Missense
c.660C>T; p.Y220Y; 19:15191979-15191979	breast	carcinoma	Substitution - coding silent
c.2944C>T; p.P982S; 19:15181011-15181011	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3280C>T; p.Q1094*; 19:15180119-15180119	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.3259C>T; p.P1087S; 19:15180140-15180140	skin	malignant_melanoma	Substitution - Missense
c.5354G>A; p.R1785H; 19:15167257-15167257	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2528G>A; p.G843D; 19:15184333-15184333	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2492G>A; p.G831E; 19:15184369-15184369	skin; leg	malignant_melanoma	Substitution - Missense
c.2492G>A; p.G831E; 19:15184369-15184369	skin; leg	malignant_melanoma	Substitution - Missense
c.752G>C; p.C251S; 19:15191795-15191795	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.901G>A; p.V301M; 19:15191559-15191559	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1207G>A; p.E403K; 19:15189160-15189160	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.901G>A; p.V301M; 19:15191559-15191559	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.171G>T; p.Q57H; 19:15197526-15197526	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2052G>A; p.P684P; 19:15185579-15185579	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2984C>T; p.P995L; 19:15180971-15180971	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3161T>G; p.L1054R; 19:15180238-15180238	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.5465C>T; p.S1822F; 19:15165989-15165989	skin	malignant_melanoma	Substitution - Missense
c.6953A>T; p.Q2318L; 19:15160675-15160675	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.5548G>A; p.A1850T; 19:15165906-15165906	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3523C>T; p.R1175W; 19:15179220-15179220	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.545G>A; p.R182H; 19:15192094-15192094	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.5173G>A; p.E1725K; 19:15170112-15170112	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.545G>A; p.R182H; 19:15192094-15192094	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.6953A>T; p.Q2318L; 19:15160675-15160675	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.6809C>T; p.T2270M; 19:15160819-15160819	central_nervous_system; brain	glioma	Substitution - Missense
c.2716G>A; p.A906T; 19:15181652-15181652	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3567C>T; p.F1189F; 19:15179176-15179176	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1122G>C; p.R374R; 19:15189343-15189343	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.626G>A; p.G209E; 19:15192013-15192013	skin	malignant_melanoma	Substitution - Missense
c.5317G>A; p.G1773S; 19:15167294-15167294	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3580C>T; p.P1194S; 19:15179163-15179163	skin	malignant_melanoma	Substitution - Missense
c.2659G>A; p.D887N; 19:15181709-15181709	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4501G>T; p.A1501S; 19:15174303-15174303	thyroid	other; neoplasm	Substitution - Missense
c.5006G>A; p.R1669H; 19:15170439-15170439	central_nervous_system; brain	glioma	Substitution - Missense
c.1236G>T; p.Q412H; 19:15189131-15189131	pancreas	carcinoma	Substitution - Missense
c.1236G>T; p.Q412H; 19:15189131-15189131	pancreas	carcinoma	Substitution - Missense
c.2094C>A; p.P698P; 19:15185537-15185537	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.5800G>A; p.A1934T; 19:15165383-15165383	skin; neck	malignant_melanoma	Substitution - Missense
c.5006G>A; p.R1669H; 19:15170439-15170439	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6597G>A; p.G2199G; 19:15161031-15161031	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1291G>A; p.D431N; 19:15189076-15189076	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3599delT; p.L1200fs*72; 19:15179144-15179144	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3011G>A; p.C1004Y; 19:15180812-15180812	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.6029A>G; p.D2010G; 19:15161599-15161599	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.105G>C; p.G35G; 19:15200801-15200801	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2538C>T; p.C846C; 19:15184323-15184323	thyroid	other; neoplasm	Substitution - coding silent
c.3087C>T; p.S1029S; 19:15180736-15180736	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1193-1G>T; p.?; 19:15189175-15189175	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Unknown
c.1193-1G>T; p.?; 19:15189175-15189175	urinary_tract; bladder	carcinoma	Unknown
c.1238G>A; p.G413D; 19:15189129-15189129	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2834C>T; p.S945L; 19:15181121-15181121	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5744G>A; p.R1915H; 19:15165439-15165439	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.2084delC; p.P695fs*165; 19:15185547-15185547	oesophagus; lower_third	carcinoma; adenocarcinoma	Deletion - Frameshift
c.5744G>A; p.R1915H; 19:15165439-15165439	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5081G>A; p.R1694Q; 19:15170364-15170364	skin	malignant_melanoma	Substitution - Missense
c.412C>A; p.P138T; 19:15192227-15192227	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1790G>C; p.C597S; 19:15187155-15187155	central_nervous_system; brain	glioma; astrocytoma_Grade_II	Substitution - Missense
c.3463G>A; p.V1155M; 19:15179280-15179280	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3150G>T; p.R1050R; 19:15180249-15180249	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.6200C>T; p.P2067L; 19:15161428-15161428	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1095C>G; p.I365M; 19:15189370-15189370	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1095C>G; p.I365M; 19:15189370-15189370	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.3150G>T; p.R1050R; 19:15180249-15180249	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.5856G>A; p.V1952V; 19:15162522-15162522	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.5856G>A; p.V1952V; 19:15162522-15162522	skin	malignant_melanoma	Substitution - coding silent
c.3310G>T; p.G1104W; 19:15180089-15180089	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4088G>62; p.C1363fs*1; 19:15177840-15177840	central_nervous_system; brainstem	glioma; astrocytoma_Grade_IV	Unknown
c.1300G>A; p.E434K; 19:15189067-15189067	upper_aerodigestive_tract; sinonasal_and_nasal_cavity	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6287C>T; p.S2096L; 19:15161341-15161341	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.6287C>T; p.S2096L; 19:15161341-15161341	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.5500C>T; p.R1834W; 19:15165954-15165954	liver	carcinoma	Substitution - Missense
c.125delC; p.P42fs*194; 19:15197572-15197572	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4821C>T; p.A1607A; 19:15170741-15170741	liver	carcinoma	Substitution - coding silent
c.125delC; p.P42fs*194; 19:15197572-15197572	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.5500C>T; p.R1834W; 19:15165954-15165954	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.4821C>T; p.A1607A; 19:15170741-15170741	liver	carcinoma	Substitution - coding silent
c.731G>A; p.R244Q; 19:15191816-15191816	skin	malignant_melanoma	Substitution - Missense
c.5451A>G; p.S1817S; 19:15166003-15166003	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.731G>A; p.R244Q; 19:15191816-15191816	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.900C>T; p.C300C; 19:15191560-15191560	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3648G>A; p.A1216A; 19:15179095-15179095	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4986C>G; p.V1662V; 19:15170459-15170459	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.6884C>G; p.S2295C; 19:15160744-15160744	skin	malignant_melanoma	Substitution - Missense
c.5809G>A; p.E1937K; 19:15165374-15165374	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5809G>A; p.E1937K; 19:15165374-15165374	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5111T>G; p.M1704R; 19:15170334-15170334	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.6005A>G; p.D2002G; 19:15161623-15161623	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1192+1G>A; p.?; 19:15189272-15189272	skin	malignant_melanoma	Unknown
c.2536T>C; p.C846R; 19:15184325-15184325	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1300G>T; p.E434*; 19:15189067-15189067	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.3607G>A; p.E1203K; 19:15179136-15179136	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3607G>A; p.E1203K; 19:15179136-15179136	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2776C>T; p.P926S; 19:15181592-15181592	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5164A>G; p.M1722V; 19:15170121-15170121	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5633C>T; p.T1878I; 19:15165821-15165821	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5678G>A; p.R1893Q; 19:15165505-15165505	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.5678G>A; p.R1893Q; 19:15165505-15165505	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.5678G>A; p.R1893Q; 19:15165505-15165505	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.797G>A; p.W266*; 19:15191750-15191750	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Nonsense
c.5678G>A; p.R1893Q; 19:15165505-15165505	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1832G>A; p.G611E; 19:15187113-15187113	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3568C>T; p.R1190C; 19:15179175-15179175	pancreas	carcinoma	Substitution - Missense
c.2120G>A; p.G707D; 19:15185511-15185511	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5542C>A; p.R1848S; 19:15165912-15165912	skin	malignant_melanoma	Substitution - Missense
c.1036+1G>T; p.?; 19:15191423-15191423	oesophagus	carcinoma; squamous_cell_carcinoma	Unknown
c.6143C>T; p.A2048V; 19:15161485-15161485	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.6143C>T; p.A2048V; 19:15161485-15161485	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.5029C>T; p.P1677S; 19:15170416-15170416	skin	malignant_melanoma	Substitution - Missense
c.5065G>T; p.G1689C; 19:15170380-15170380	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.6143C>T; p.A2048V; 19:15161485-15161485	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.5348A>G; p.N1783S; 19:15167263-15167263	soft_tissue; blood_vessel	angiosarcoma	Substitution - Missense
c.5987C>T; p.A1996V; 19:15161641-15161641	pancreas	carcinoma	Substitution - Missense
c.6092G>A; p.R2031H; 19:15161536-15161536	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6092G>A; p.R2031H; 19:15161536-15161536	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.850G>A; p.A284T; 19:15191610-15191610	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.6092G>A; p.R2031H; 19:15161536-15161536	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6633C>A; p.Y2211*; 19:15160995-15160995	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.4912G>A; p.E1638K; 19:15170533-15170533	skin	malignant_melanoma	Substitution - Missense
c.6854G>T; p.G2285V; 19:15160774-15160774	thyroid	other; neoplasm	Substitution - Missense
c.4926G>A; p.P1642P; 19:15170519-15170519	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.401G>C; p.C134S; 19:15192238-15192238	pancreas	carcinoma	Substitution - Missense
c.2589G>A; p.S863S; 19:15181779-15181779	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.3314delG; p.G1105fs*167; 19:15180085-15180085	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.661G>A; p.D221N; 19:15191978-15191978	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5993G>A; p.R1998H; 19:15161635-15161635	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2202C>T; p.A734A; 19:15185351-15185351	lung	carcinoma; undifferentiated_carcinoma	Substitution - coding silent
c.5319C>T; p.G1773G; 19:15167292-15167292	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.6511G>A; p.D2171N; 19:15161117-15161117	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2330C>A; p.P777Q; 19:15184986-15184986	liver	carcinoma	Substitution - Missense
c.4364A>G; p.N1455S; 19:15177564-15177564	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1109C>T; p.P370L; 19:15189356-15189356	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4563A>G; p.P1521P; 19:15174241-15174241	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4563A>G; p.P1521P; 19:15174241-15174241	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4563A>G; p.P1521P; 19:15174241-15174241	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4563A>G; p.P1521P; 19:15174241-15174241	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4563A>G; p.P1521P; 19:15174241-15174241	breast	carcinoma	Substitution - coding silent
c.4451G>A; p.C1484Y; 19:15174353-15174353	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4563A>G; p.P1521P; 19:15174241-15174241	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4563A>G; p.P1521P; 19:15174241-15174241	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4563A>G; p.P1521P; 19:15174241-15174241	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4563A>G; p.P1521P; 19:15174241-15174241	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4563A>G; p.P1521P; 19:15174241-15174241	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4563A>G; p.P1521P; 19:15174241-15174241	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1528G>A; p.E510K; 19:15187959-15187959	skin	malignant_melanoma	Substitution - Missense
c.1321C>T; p.R441*; 19:15189046-15189046	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.972C>T; p.F324F; 19:15191488-15191488	skin; nipple	malignant_melanoma	Substitution - coding silent
c.1774C>A; p.R592S; 19:15187171-15187171	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.364C>T; p.P122S; 19:15192275-15192275	skin	malignant_melanoma	Substitution - Missense
c.714C>T; p.D238D; 19:15191833-15191833	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.69delC; p.V24fs*10; 19:15200837-15200837	autonomic_ganglia	neuroblastoma	Deletion - Frameshift
c.5717G>A; p.G1906D; 19:15165466-15165466	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3591C>A; p.Y1197*; 19:15179152-15179152	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.4636C>T; p.R1546C; 19:15174168-15174168	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4619G>A; p.R1540H; 19:15174185-15174185	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5778C>T; p.I1926I; 19:15165405-15165405	skin	malignant_melanoma	Substitution - coding silent
c.5639T>C; p.V1880A; 19:15165815-15165815	urinary_tract; bladder	carcinoma	Substitution - Missense
c.6026G>A; p.R2009Q; 19:15161602-15161602	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.816G>A; p.T272T; 19:15191644-15191644	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.337C>T; p.R113*; 19:15192380-15192380	oesophagus	carcinoma; adenocarcinoma	Substitution - Nonsense
c.816G>A; p.T272T; 19:15191644-15191644	skin	malignant_melanoma	Substitution - coding silent
c.629G>C; p.G210A; 19:15192010-15192010	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1319G>A; p.C440Y; 19:15189048-15189048	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5404_5405insG; p.A1802fs*8; 19:15166049-15166050	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.5404_5405insG; p.A1802fs*8; 19:15166049-15166050	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1073A>C; p.N358T; 19:15189392-15189392	thyroid	other; neoplasm	Substitution - Missense
c.5404_5405insG; p.A1802fs*8; 19:15166049-15166050	thyroid	carcinoma; anaplastic_carcinoma	Insertion - Frameshift
c.2073C>G; p.L691L; 19:15185558-15185558	breast	carcinoma	Substitution - coding silent
c.1522G>A; p.V508M; 19:15187965-15187965	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2467C>A; p.H823N; 19:15184394-15184394	central_nervous_system; brainstem	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.312C>T; p.F104F; 19:15192405-15192405	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4867C>T; p.P1623S; 19:15170695-15170695	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1322G>A; p.R441Q; 19:15189045-15189045	skin	malignant_melanoma	Substitution - Missense
c.6111C>T; p.H2037H; 19:15161517-15161517	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.5390C>G; p.S1797C; 19:15166064-15166064	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1102A>T; p.T368S; 19:15189363-15189363	breast	carcinoma	Substitution - Missense
c.5383C>A; p.L1795M; 19:15166071-15166071	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.4615C>T; p.L1539L; 19:15174189-15174189	skin; upper_leg	malignant_melanoma	Substitution - coding silent
c.1205G>T; p.C402F; 19:15189162-15189162	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.994C>A; p.R332S; 19:15191466-15191466	liver	carcinoma	Substitution - Missense
c.1541C>T; p.T514M; 19:15187946-15187946	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.994C>A; p.R332S; 19:15191466-15191466	liver	carcinoma	Substitution - Missense
c.2671T>A; p.C891S; 19:15181697-15181697	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3016C>T; p.R1006C; 19:15180807-15180807	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4669C>T; p.P1557S; 19:15174135-15174135	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5841G>T; p.A1947A; 19:15162537-15162537	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.908T>C; p.V303A; 19:15191552-15191552	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1220G>T; p.R407M; 19:15189147-15189147	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.6325C>A; p.R2109R; 19:15161303-15161303	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.6923G>A; p.G2308E; 19:15160705-15160705	liver	carcinoma	Substitution - Missense
c.6923G>A; p.G2308E; 19:15160705-15160705	liver	carcinoma	Substitution - Missense
c.4999C>T; p.R1667C; 19:15170446-15170446	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1411G>T; p.D471Y; 19:15188316-15188316	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3692G>A; p.R1231H; 19:15179051-15179051	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5510G>A; p.R1837H; 19:15165944-15165944	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.6626C>T; p.P2209L; 19:15161002-15161002	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.5510G>A; p.R1837H; 19:15165944-15165944	skin	malignant_melanoma	Substitution - Missense
c.5510G>A; p.R1837H; 19:15165944-15165944	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3692G>A; p.R1231H; 19:15179051-15179051	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3197G>A; p.S1066N; 19:15180202-15180202	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4724C>T; p.P1575L; 19:15174080-15174080	skin	malignant_melanoma	Substitution - Missense
c.2742A>G; p.P914P; 19:15181626-15181626	thyroid	other; neoplasm	Substitution - coding silent
c.4921G>A; p.V1641I; 19:15170524-15170524	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3328-9C>T; p.?; 19:15179505-15179505	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.4987A>T; p.M1663L; 19:15170458-15170458	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.3407C>T; p.S1136L; 19:15179417-15179417	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3255G>T; p.V1085V; 19:15180144-15180144	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.5095C>T; p.Q1699*; 19:15170350-15170350	skin; upper_leg	malignant_melanoma	Substitution - Nonsense
c.3483G>A; p.E1161E; 19:15179260-15179260	skin	malignant_melanoma	Substitution - coding silent
c.1674C>T; p.R558R; 19:15187271-15187271	large_intestine; colon	carcinoma	Substitution - coding silent
c.5644G>A; p.A1882T; 19:15165810-15165810	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1674C>T; p.R558R; 19:15187271-15187271	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1246C>T; p.L416L; 19:15189121-15189121	pancreas	carcinoma	Substitution - coding silent
c.4576C>T; p.R1526C; 19:15174228-15174228	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1193-4G>A; p.?; 19:15189178-15189178	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Unknown
c.6580_6581insC; p.Q2194fs*48; 19:15161047-15161048	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.4637G>A; p.R1546H; 19:15174167-15174167	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.4835G>A; p.G1612E; 19:15170727-15170727	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5807A>G; p.D1936G; 19:15165376-15165376	oesophagus	carcinoma	Substitution - Missense
c.5114+2T>A; p.?; 19:15170329-15170329	oesophagus	carcinoma; squamous_cell_carcinoma	Unknown
c.1285G>A; p.E429K; 19:15189082-15189082	skin	malignant_melanoma	Substitution - Missense
c.4402A>C; p.N1468H; 19:15177526-15177526	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.4426G>A; p.A1476T; 19:15174378-15174378	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5114+2T>A; p.?; 19:15170329-15170329	oesophagus	carcinoma; squamous_cell_carcinoma	Unknown
c.1737C>A; p.C579*; 19:15187208-15187208	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.815C>T; p.T272M; 19:15191645-15191645	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3632C>T; p.S1211L; 19:15179111-15179111	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2653G>A; p.A885T; 19:15181715-15181715	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3967T>C; p.S1323P; 19:15177961-15177961	thyroid	other; neoplasm	Substitution - Missense
c.5242C>T; p.R1748C; 19:15167369-15167369	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; primary_central_nervous_system_lymphoma	Substitution - Missense
c.1068C>A; p.V356V; 19:15189397-15189397	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.6383C>T; p.A2128V; 19:15161245-15161245	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.3254T>G; p.V1085G; 19:15180145-15180145	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.747delG; p.T250fs*122; 19:15191800-15191800	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1121G>T; p.R374L; 19:15189344-15189344	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1642G>A; p.D548N; 19:15187303-15187303	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.5980C>A; p.H1994N; 19:15161648-15161648	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5102C>T; p.A1701V; 19:15170343-15170343	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.5839G>A; p.A1947T; 19:15162539-15162539	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1642G>A; p.D548N; 19:15187303-15187303	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.5102C>T; p.A1701V; 19:15170343-15170343	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5779G>A; p.A1927T; 19:15165404-15165404	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.5323G>A; p.A1775T; 19:15167288-15167288	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5323G>A; p.A1775T; 19:15167288-15167288	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.5779G>A; p.A1927T; 19:15165404-15165404	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.63G>A; p.P21P; 19:15200843-15200843	liver	carcinoma	Substitution - coding silent
c.6654C>T; p.G2218G; 19:15160974-15160974	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.6654C>T; p.G2218G; 19:15160974-15160974	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.6102delC; p.G2035fs*50; 19:15161526-15161526	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.63G>A; p.P21P; 19:15200843-15200843	liver	carcinoma	Substitution - coding silent
c.423C>A; p.R141R; 19:15192216-15192216	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.1732C>G; p.R578G; 19:15187213-15187213	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4559C>T; p.P1520L; 19:15174245-15174245	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4560G>A; p.P1520P; 19:15174244-15174244	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.753C>T; p.C251C; 19:15191794-15191794	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3573C>T; p.C1191C; 19:15179170-15179170	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2275A>T; p.T759S; 19:15185278-15185278	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2275A>T; p.T759S; 19:15185278-15185278	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4974C>A; p.L1658L; 19:15170471-15170471	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.224G>A; p.R75Q; 19:15192493-15192493	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2741C>T; p.P914L; 19:15181627-15181627	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.6601C>T; p.P2201S; 19:15161027-15161027	central_nervous_system; brain	glioma	Substitution - Missense
c.1521C>G; p.D507E; 19:15187966-15187966	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5281C>T; p.R1761C; 19:15167330-15167330	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.754G>A; p.V252M; 19:15191793-15191793	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1594C>T; p.R532C; 19:15187893-15187893	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4806C>T; p.P1602P; 19:15170756-15170756	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.6785C>G; p.S2262C; 19:15160843-15160843	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.768C>T; p.N256N; 19:15191779-15191779	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3371A>G; p.D1124G; 19:15179453-15179453	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.5403G>T; p.G1801G; 19:15166051-15166051	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2668G>A; p.E890K; 19:15181700-15181700	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3091C>T; p.R1031C; 19:15180732-15180732	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5161T>G; p.W1721G; 19:15170124-15170124	thyroid	other; neoplasm	Substitution - Missense
c.3425C>A; p.A1142D; 19:15179399-15179399	large_intestine; rectum	NS	Substitution - Missense
c.4834G>T; p.G1612*; 19:15170728-15170728	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.4975G>A; p.V1659I; 19:15170470-15170470	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.3433C>G; p.L1145V; 19:15179391-15179391	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1850G>C; p.C617S; 19:15186979-15186979	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3096C>A; p.L1032L; 19:15180727-15180727	breast	carcinoma	Substitution - coding silent
c.475G>A; p.V159M; 19:15192164-15192164	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1195G>A; p.A399T; 19:15189172-15189172	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5338A>G; p.M1780V; 19:15167273-15167273	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2182C>T; p.R728C; 19:15185371-15185371	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2566+2T>G; p.?; 19:15184293-15184293	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.2080C>T; p.P694S; 19:15185551-15185551	oesophagus; upper_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3602G>A; p.R1201H; 19:15179141-15179141	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3602G>A; p.R1201H; 19:15179141-15179141	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.179C>T; p.S60F; 19:15197518-15197518	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5914-1G>T; p.?; 19:15161715-15161715	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.5200G>A; p.V1734I; 19:15167411-15167411	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3711C>A; p.G1237G; 19:15179032-15179032	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - coding silent
c.2093C>T; p.P698L; 19:15185538-15185538	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2182C>T; p.R728C; 19:15185371-15185371	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.6569C>T; p.A2190V; 19:15161059-15161059	liver	carcinoma	Substitution - Missense
c.4575G>T; p.L1525L; 19:15174229-15174229	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.6569C>T; p.A2190V; 19:15161059-15161059	liver	carcinoma	Substitution - Missense
c.6897C>T; p.S2299S; 19:15160731-15160731	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.5488C>T; p.Q1830*; 19:15165966-15165966	prostate	carcinoma	Substitution - Nonsense
c.4470G>A; p.T1490T; 19:15174334-15174334	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.5068C>T; p.H1690Y; 19:15170377-15170377	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4805C>T; p.P1602L; 19:15170757-15170757	skin	malignant_melanoma	Substitution - Missense
c.5713G>C; p.D1905H; 19:15165470-15165470	breast	carcinoma	Substitution - Missense
c.4625C>T; p.S1542L; 19:15174179-15174179	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1083C>T; p.H361H; 19:15189382-15189382	pancreas	carcinoma	Substitution - coding silent
c.5932C>T; p.L1978L; 19:15161696-15161696	skin	malignant_melanoma	Substitution - coding silent
c.5733C>T; p.I1911I; 19:15165450-15165450	skin	malignant_melanoma	Substitution - coding silent
c.5026T>C; p.F1676L; 19:15170419-15170419	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3563G>A; p.G1188D; 19:15179180-15179180	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2629C>T; p.P877S; 19:15181739-15181739	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5641A>C; p.T1881P; 19:15165813-15165813	breast	carcinoma	Substitution - Missense
c.3155A>G; p.E1052G; 19:15180244-15180244	breast	carcinoma	Substitution - Missense
c.2322C>T; p.P774P; 19:15184994-15184994	pancreas	carcinoma	Substitution - coding silent
c.3563G>A; p.G1188D; 19:15179180-15179180	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.4529G>A; p.R1510H; 19:15174275-15174275	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4529G>A; p.R1510H; 19:15174275-15174275	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1919G>A; p.R640H; 19:15186910-15186910	liver	carcinoma	Substitution - Missense
c.1919G>A; p.R640H; 19:15186910-15186910	liver	carcinoma	Substitution - Missense
c.1852G>A; p.E618K; 19:15186977-15186977	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1785C>T; p.G595G; 19:15187160-15187160	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1440C>T; p.N480N; 19:15188287-15188287	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3568C>G; p.R1190G; 19:15179175-15179175	skin	malignant_melanoma	Substitution - Missense
c.1144G>A; p.G382S; 19:15189321-15189321	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.6537C>T; p.A2179A; 19:15161091-15161091	skin	malignant_melanoma	Substitution - coding silent
c.5984_5985delTT; p.F1995fs*4; 19:15161643-15161644	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3299G>A; p.R1100H; 19:15180100-15180100	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3299G>A; p.R1100H; 19:15180100-15180100	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4997G>A; p.R1666Q; 19:15170448-15170448	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.649G>A; p.D217N; 19:15191990-15191990	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5386G>T; p.A1796S; 19:15166068-15166068	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1177G>A; p.D393N; 19:15189288-15189288	skin	malignant_melanoma	Substitution - Missense

The somatic mutations from COSMIC database