Entrez Gene

Basic Information
Gene ID	4318
Name	MMP9

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.1792C>A; p.P598T; 20:46014165-46014165	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1354C>T; p.R452W; 20:46013278-46013278	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.588C>T; p.P196P; 20:46010989-46010989	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.580C>A; p.P194T; 20:46010981-46010981	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.960C>T; p.Y320Y; 20:46011710-46011710	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.960C>T; p.Y320Y; 20:46011710-46011710	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1731G>T; p.K577N; 20:46013777-46013777	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.717C>T; p.R239R; 20:46011210-46011210	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.824-1G>A; p.?; 20:46011573-46011573	skin	malignant_melanoma	Unknown
c.77C>T; p.S26F; 20:46009003-46009003	skin	malignant_melanoma	Substitution - Missense
c.1337G>A; p.R446H; 20:46013261-46013261	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1750+2T>C; p.?; 20:46013798-46013798	large_intestine; rectum	carcinoma; adenocarcinoma	Unknown
c.489C>T; p.D163D; 20:46010600-46010600	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.673G>A; p.A225T; 20:46011166-46011166	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1108C>T; p.R370C; 20:46012247-46012247	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1266G>T; p.M422I; 20:46012518-46012518	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1076C>T; p.S359L; 20:46012215-46012215	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1605G>T; p.K535N; 20:46013529-46013529	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.836A>G; p.Q279R; 20:46011586-46011586	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.998C>A; p.A333D; 20:46012137-46012137	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1821A>C; p.G607G; 20:46014194-46014194	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.1821A>C; p.G607G; 20:46014194-46014194	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1821A>C; p.G607G; 20:46014194-46014194	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1821A>C; p.G607G; 20:46014194-46014194	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1821A>C; p.G607G; 20:46014194-46014194	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1821A>C; p.G607G; 20:46014194-46014194	thyroid	other; neoplasm	Substitution - coding silent
c.1821A>C; p.G607G; 20:46014194-46014194	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1821A>C; p.G607G; 20:46014194-46014194	thyroid	other; neoplasm	Substitution - coding silent
c.1821A>C; p.G607G; 20:46014194-46014194	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1821A>C; p.G607G; 20:46014194-46014194	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1284G>C; p.G428G; 20:46012536-46012536	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2053C>T; p.R685W; 20:46016297-46016297	large_intestine; colon	carcinoma	Substitution - Missense
c.2053C>T; p.R685W; 20:46016297-46016297	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2053C>T; p.R685W; 20:46016297-46016297	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.105G>C; p.L35L; 20:46009031-46009031	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.400C>T; p.R134W; 20:46010511-46010511	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.828C>G; p.L276L; 20:46011578-46011578	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1390C>T; p.P464S; 20:46013314-46013314	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.584G>A; p.G195D; 20:46010985-46010985	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.965G>A; p.R322Q; 20:46011715-46011715	urinary_tract; bladder	carcinoma	Substitution - Missense
c.459G>A; p.P153P; 20:46010570-46010570	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1080C>A; p.T360T; 20:46012219-46012219	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1049C>A; p.P350H; 20:46012188-46012188	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1072T>C; p.Y358H; 20:46012211-46012211	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.490G>A; p.A164T; 20:46010601-46010601	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.824G>A; p.R275K; 20:46011574-46011574	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1707G>T; p.S569S; 20:46013753-46013753	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1236C>A; p.S412S; 20:46012488-46012488	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.682G>A; p.A228T; 20:46011175-46011175	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.72C>A; p.R24R; 20:46008998-46008998	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1420A>C; p.T474P; 20:46013344-46013344	skin	malignant_melanoma	Substitution - Missense
c.44G>A; p.G15D; 20:46008970-46008970	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.711G>A; p.E237E; 20:46011204-46011204	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.504C>A; p.I168I; 20:46010615-46010615	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1120G>A; p.A374T; 20:46012259-46012259	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.436G>A; p.A146T; 20:46010547-46010547	pancreas	carcinoma	Substitution - Missense
c.791C>A; p.T264N; 20:46011284-46011284	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1217C>T; p.A406V; 20:46012469-46012469	central_nervous_system; brain	glioma	Substitution - Missense
c.1683C>T; p.P561P; 20:46013729-46013729	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1945G>A; p.E649K; 20:46014414-46014414	skin; ear	malignant_melanoma	Substitution - Missense
c.1573G>A; p.A525T; 20:46013497-46013497	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.742G>A; p.G248S; 20:46011235-46011235	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2042G>A; p.R681H; 20:46016286-46016286	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.449C>T; p.A150V; 20:46010560-46010560	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2040G>A; p.W680*; 20:46016284-46016284	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1439G>A; p.R480H; 20:46013363-46013363	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.655C>T; p.P219S; 20:46011148-46011148	skin	malignant_melanoma	Substitution - Missense
c.62C>T; p.P21L; 20:46008988-46008988	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.741C>T; p.D247D; 20:46011234-46011234	breast	carcinoma	Substitution - coding silent
c.1583G>A; p.G528E; 20:46013507-46013507	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.655C>T; p.P219S; 20:46011148-46011148	skin	malignant_melanoma	Substitution - Missense
c.753C>T; p.D251D; 20:46011246-46011246	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.753C>T; p.D251D; 20:46011246-46011246	breast	carcinoma	Substitution - coding silent
c.1610+3G>T; p.?; 20:46013537-46013537	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Unknown
c.952G>A; p.A318T; 20:46011702-46011702	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.622G>T; p.E208*; 20:46011023-46011023	liver	carcinoma; hepatocellular_carcinoma	Substitution - Nonsense
c.622G>T; p.E208*; 20:46011023-46011023	liver	carcinoma; hepatocellular_carcinoma	Substitution - Nonsense
c.1646G>A; p.R549Q; 20:46013692-46013692	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1848C>T; p.A616A; 20:46014221-46014221	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.604G>A; p.A202T; 20:46011005-46011005	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.604G>A; p.A202T; 20:46011005-46011005	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.604G>A; p.A202T; 20:46011005-46011005	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1285delC; p.L431fs*6; 20:46012537-46012537	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1545C>A; p.A515A; 20:46013469-46013469	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.817A>T; p.S273C; 20:46011310-46011310	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1450G>T; p.G484C; 20:46013374-46013374	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.656C>A; p.P219Q; 20:46011149-46011149	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.477G>A; p.V159V; 20:46010588-46010588	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1174+1G>C; p.?; 20:46012314-46012314	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1271G>T; p.R424L; 20:46012523-46012523	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1144G>A; p.D382N; 20:46012283-46012283	skin	malignant_melanoma	Substitution - Missense
c.1973C>A; p.P658H; 20:46014442-46014442	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1144G>A; p.D382N; 20:46012283-46012283	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.652G>T; p.V218F; 20:46011145-46011145	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.692A>C; p.H231P; 20:46011185-46011185	breast	carcinoma	Substitution - Missense
c.322C>G; p.Q108E; 20:46010049-46010049	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.823+1G>A; p.?; 20:46011317-46011317	stomach	carcinoma; adenocarcinoma	Unknown
c.788A>G; p.D263G; 20:46011281-46011281	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.17C>G; p.P6R; 20:46008943-46008943	prostate	carcinoma	Substitution - Missense
c.1026G>T; p.S342S; 20:46012165-46012165	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1309A>C; p.N437H; 20:46012561-46012561	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2121C>A; p.D707E; 20:46016365-46016365	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1901+2T>G; p.?; 20:46014276-46014276	ovary	other; neoplasm	Unknown
c.472C>T; p.R158C; 20:46010583-46010583	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.612C>T; p.F204F; 20:46011013-46011013	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.299G>A; p.G100E; 20:46010026-46010026	skin	malignant_melanoma	Substitution - Missense
c.430G>A; p.A144T; 20:46010541-46010541	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.265G>A; p.A89T; 20:46009992-46009992	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1395G>A; p.P465P; 20:46013319-46013319	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2015A>G; p.Y672C; 20:46016259-46016259	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.758T>C; p.L253S; 20:46011251-46011251	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.997+5C>T; p.?; 20:46011752-46011752	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.997+5C>T; p.?; 20:46011752-46011752	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.415G>A; p.D139N; 20:46010526-46010526	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1743C>A; p.F581L; 20:46013789-46013789	breast	carcinoma	Substitution - Missense
c.1394C>A; p.P465Q; 20:46013318-46013318	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.645C>T; p.G215G; 20:46011046-46011046	pancreas	carcinoma	Substitution - coding silent
c.1707G>A; p.S569S; 20:46013753-46013753	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1209C>T; p.F403F; 20:46012461-46012461	skin	malignant_melanoma	Substitution - coding silent
c.1210G>A; p.G404S; 20:46012462-46012462	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1334C>G; p.P445R; 20:46013258-46013258	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.1095C>A; p.G365G; 20:46012234-46012234	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.2088C>T; p.Y696Y; 20:46016332-46016332	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1131G>A; p.S377S; 20:46012270-46012270	skin	malignant_melanoma	Substitution - coding silent
c.1131G>A; p.S377S; 20:46012270-46012270	endometrium	carcinoma; serous_carcinoma	Substitution - coding silent
c.104T>C; p.L35P; 20:46009030-46009030	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.104T>C; p.L35P; 20:46009030-46009030	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1077G>A; p.S359S; 20:46012216-46012216	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1192G>A; p.V398M; 20:46012444-46012444	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1192G>A; p.V398M; 20:46012444-46012444	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1438C>T; p.R480C; 20:46013362-46013362	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.419C>T; p.A140V; 20:46010530-46010530	skin	malignant_melanoma	Substitution - Missense
c.1324C>A; p.L442I; 20:46012576-46012576	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.419C>T; p.A140V; 20:46010530-46010530	skin	malignant_melanoma	Substitution - Missense
c.1144G>T; p.D382Y; 20:46012283-46012283	skin	malignant_melanoma	Substitution - Missense
c.2089G>A; p.V697M; 20:46016333-46016333	pancreas	carcinoma	Substitution - Missense
c.800G>C; p.R267P; 20:46011293-46011293	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.901G>A; p.A301T; 20:46011651-46011651	breast	carcinoma	Substitution - Missense
c.1166C>T; p.P389L; 20:46012305-46012305	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.684G>A; p.A228A; 20:46011177-46011177	pancreas	NS	Substitution - coding silent
c.683C>T; p.A228V; 20:46011176-46011176	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1917G>T; p.A639A; 20:46014386-46014386	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1649C>T; p.P550L; 20:46013695-46013695	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.796G>A; p.D266N; 20:46011289-46011289	pancreas	carcinoma	Substitution - Missense
c.1397C>T; p.T466M; 20:46013321-46013321	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1339C>A; p.P447T; 20:46013263-46013263	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1397C>T; p.T466M; 20:46013321-46013321	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.796G>A; p.D266N; 20:46011289-46011289	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.864C>A; p.C288*; 20:46011614-46011614	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1390_1391CC>TT; p.P464F; 20:46013314-46013315	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.280A>G; p.M94V; 20:46010007-46010007	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.280A>G; p.M94V; 20:46010007-46010007	liver	carcinoma	Substitution - Missense
c.1143C>A; p.S381R; 20:46012282-46012282	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1143C>T; p.S381S; 20:46012282-46012282	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1572C>A; p.I524I; 20:46013496-46013496	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.648C>T; p.V216V; 20:46011049-46011049	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.455C>T; p.T152M; 20:46010566-46010566	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.984C>A; p.F328L; 20:46011734-46011734	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1218G>T; p.A406A; 20:46012470-46012470	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1211G>A; p.G404D; 20:46012463-46012463	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.327C>T; p.T109T; 20:46010054-46010054	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.15G>A; p.Q5Q; 20:46008941-46008941	breast	carcinoma	Substitution - coding silent
c.129G>C; p.Q43H; 20:46009055-46009055	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.725C>T; p.S242F; 20:46011218-46011218	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1385C>T; p.T462M; 20:46013309-46013309	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.923C>A; p.S308Y; 20:46011673-46011673	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.525C>T; p.H175H; 20:46010926-46010926	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2007G>T; p.E669D; 20:46016251-46016251	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1611G>T; p.G537G; 20:46013657-46013657	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1757A>T; p.Q586L; 20:46014130-46014130	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.562C>A; p.L188M; 20:46010963-46010963	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1637delG; p.S548fs*66; 20:46013683-46013683	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1722G>A; p.R574R; 20:46013768-46013768	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.427C>T; p.R143C; 20:46010538-46010538	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.167G>A; p.R56Q; 20:46009894-46009894	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1216G>A; p.A406T; 20:46012468-46012468	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1216G>A; p.A406T; 20:46012468-46012468	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1216G>A; p.A406T; 20:46012468-46012468	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.83T>C; p.L28P; 20:46009009-46009009	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1099G>A; p.G367R; 20:46012238-46012238	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2055G>T; p.R685R; 20:46016299-46016299	liver	carcinoma	Substitution - coding silent
c.943G>A; p.A315T; 20:46011693-46011693	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2114C>A; p.P705H; 20:46016358-46016358	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1831G>A; p.A611T; 20:46014204-46014204	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1496C>G; p.A499G; 20:46013420-46013420	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1431C>A; p.P477P; 20:46013355-46013355	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent

The somatic mutations from COSMIC database