Entrez Gene

Basic Information
Gene ID	4313
Name	MMP2

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.855C>T; p.N285N; 16:55488565-55488565	stomach	adenocarcinoma	Substitution - coding silent
c.855C>T; p.N285N; 16:55488565-55488565	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - coding silent
c.855C>T; p.N285N; 16:55488565-55488565	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	Substitution - coding silent
c.1245A>G; p.Q415Q; 16:55491865-55491865	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1856C>T; p.A619V; 16:55502865-55502865	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.627C>T; p.D209D; 16:55485396-55485396	stomach	adenocarcinoma	Substitution - coding silent
c.1056C>T; p.P352P; 16:55489700-55489700	skin	malignant_melanoma	Substitution - coding silent
c.384C>T; p.I128I; 16:55484019-55484019	skin; scalp	malignant_melanoma	Substitution - coding silent
c.627C>T; p.D209D; 16:55485396-55485396	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.627C>T; p.D209D; 16:55485396-55485396	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.627C>T; p.D209D; 16:55485396-55485396	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.199C>T; p.L67L; 16:55482954-55482954	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1540C>T; p.P514S; 16:55496993-55496993	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1520T>C; p.L507P; 16:55496973-55496973	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.895G>A; p.G299S; 16:55488605-55488605	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1273T>A; p.Y425N; 16:55491893-55491893	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1494G>T; p.T498T; 16:55496947-55496947	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.58C>T; p.L20L; 16:55479537-55479537	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.1770-8C>A; p.?; 16:55502771-55502771	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.349C>T; p.P117S; 16:55483104-55483104	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.96G>A; p.S32S; 16:55479575-55479575	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.96G>A; p.S32S; 16:55479575-55479575	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1713C>T; p.A571A; 16:55498392-55498392	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1198G>C; p.V400L; 16:55491818-55491818	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1015A>G; p.T339A; 16:55489659-55489659	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1743C>A; p.Y581*; 16:55498422-55498422	breast	carcinoma	Substitution - Nonsense
c.868C>A; p.P290T; 16:55488578-55488578	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1931G>T; p.S644I; 16:55505390-55505390	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.868C>A; p.P290T; 16:55488578-55488578	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.1615G>T; p.E539*; 16:55498294-55498294	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1615G>T; p.E539*; 16:55498294-55498294	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1623G>A; p.W541*; 16:55498302-55498302	skin	malignant_melanoma	Substitution - Nonsense
c.403C>T; p.L135L; 16:55484038-55484038	skin	malignant_melanoma	Substitution - coding silent
c.1893C>A; p.F631L; 16:55505352-55505352	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.538G>A; p.D180N; 16:55485307-55485307	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.912C>T; p.S304S; 16:55488622-55488622	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1684C>T; p.P562S; 16:55498363-55498363	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.102C>T; p.I34I; 16:55479581-55479581	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.596C>T; p.T199I; 16:55485365-55485365	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1095C>T; p.S365S; 16:55489739-55489739	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1681C>T; p.L561L; 16:55498360-55498360	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.1681C>T; p.L561L; 16:55498360-55498360	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1406G>A; p.C469Y; 16:55493227-55493227	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.822T>A; p.C274*; 16:55485767-55485767	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1265C>A; p.A422E; 16:55491885-55491885	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1680A>T; p.G560G; 16:55498359-55498359	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.482G>A; p.R161Q; 16:55484117-55484117	skin	malignant_melanoma	Substitution - Missense
c.1744A>T; p.I582F; 16:55498423-55498423	breast	carcinoma	Substitution - Missense
c.1529C>T; p.A510V; 16:55496982-55496982	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.482G>A; p.R161Q; 16:55484117-55484117	NS	malignant_melanoma	Substitution - Missense
c.482G>A; p.R161Q; 16:55484117-55484117	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.685G>A; p.D229N; 16:55485630-55485630	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.835C>T; p.L279L; 16:55488545-55488545	skin	malignant_melanoma	Substitution - coding silent
c.481C>T; p.R161*; 16:55484116-55484116	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1923G>T; p.E641D; 16:55505382-55505382	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.713T>A; p.L238*; 16:55485658-55485658	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.292C>T; p.R98W; 16:55483047-55483047	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.292C>T; p.R98W; 16:55483047-55483047	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.251C>T; p.P84L; 16:55483006-55483006	skin; back	malignant_melanoma	Substitution - Missense
c.225G>T; p.K75N; 16:55482980-55482980	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.436C>T; p.R146C; 16:55484071-55484071	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1965C>G; p.S655S; 16:55505424-55505424	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.436C>T; p.R146C; 16:55484071-55484071	skin	malignant_melanoma	Substitution - Missense
c.1781T>C; p.V594A; 16:55502790-55502790	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1968C>A; p.D656E; 16:55505427-55505427	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1930A>G; p.S644G; 16:55505389-55505389	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.784A>C; p.T262P; 16:55485729-55485729	breast	carcinoma	Substitution - Missense
c.1930A>G; p.S644G; 16:55505389-55505389	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1128G>A; p.A376A; 16:55489772-55489772	skin	malignant_melanoma	Substitution - coding silent
c.1128G>A; p.A376A; 16:55489772-55489772	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1070G>C; p.G357A; 16:55489714-55489714	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1070G>C; p.G357A; 16:55489714-55489714	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.869C>T; p.P290L; 16:55488579-55488579	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.869C>T; p.P290L; 16:55488579-55488579	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.8C>T; p.A3V; 16:55479487-55479487	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.308G>A; p.G103D; 16:55483063-55483063	skin	malignant_melanoma	Substitution - Missense
c.308G>A; p.G103D; 16:55483063-55483063	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1566G>T; p.A522A; 16:55497019-55497019	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1294C>A; p.R432S; 16:55491914-55491914	breast	carcinoma	Substitution - Missense
c.586G>A; p.A196T; 16:55485355-55485355	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.1548C>T; p.L516L; 16:55497001-55497001	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.759C>T; p.S253S; 16:55485704-55485704	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1548C>T; p.L516L; 16:55497001-55497001	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1964C>T; p.S655F; 16:55505423-55505423	skin	malignant_melanoma	Substitution - Missense
c.1964C>T; p.S655F; 16:55505423-55505423	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.686A>G; p.D229G; 16:55485631-55485631	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.1085G>A; p.S362N; 16:55489729-55489729	kidney	other; neoplasm	Substitution - Missense
c.456C>T; p.S152S; 16:55484091-55484091	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.456C>T; p.S152S; 16:55484091-55484091	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1932T>C; p.S644S; 16:55505391-55505391	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1646A>G; p.E549G; 16:55498325-55498325	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1932T>C; p.S644S; 16:55505391-55505391	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1479T>A; p.I493I; 16:55496932-55496932	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1691A>G; p.D564G; 16:55498370-55498370	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.1711G>A; p.A571T; 16:55498390-55498390	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.267T>C; p.L89L; 16:55483022-55483022	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.555C>T; p.D185D; 16:55485324-55485324	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.476T>G; p.F159C; 16:55484111-55484111	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.15G>A; p.M5I; 16:55479494-55479494	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.382A>C; p.I128L; 16:55484017-55484017	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.382A>C; p.I128L; 16:55484017-55484017	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.382A>C; p.I128L; 16:55484017-55484017	large_intestine; colon	carcinoma	Substitution - Missense
c.382A>C; p.I128L; 16:55484017-55484017	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.413A>G; p.E138G; 16:55484048-55484048	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.933G>T; p.T311T; 16:55488643-55488643	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - coding silent
c.1149T>C; p.D383D; 16:55489793-55489793	thyroid	other; neoplasm	Substitution - coding silent
c.435T>C; p.A145A; 16:55484070-55484070	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.698G>T; p.C233F; 16:55485643-55485643	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.557G>T; p.G186V; 16:55485326-55485326	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.846G>A; p.M282I; 16:55488556-55488556	skin	malignant_melanoma	Substitution - Missense
c.1065C>T; p.F355F; 16:55489709-55489709	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.859G>A; p.E287K; 16:55488569-55488569	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1785G>T; p.K595N; 16:55502794-55502794	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.750C>T; p.T250T; 16:55485695-55485695	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.750C>T; p.T250T; 16:55485695-55485695	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1138A>C; p.N380H; 16:55489782-55489782	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.349C>A; p.P117T; 16:55483104-55483104	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.313C>A; p.P105T; 16:55483068-55483068	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.327C>T; p.N109N; 16:55483082-55483082	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1224C>T; p.A408A; 16:55491844-55491844	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.327C>T; p.N109N; 16:55483082-55483082	pancreas	carcinoma	Substitution - coding silent
c.473G>A; p.R158Q; 16:55484108-55484108	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1493C>T; p.T498M; 16:55496946-55496946	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.589C>A; p.P197T; 16:55485358-55485358	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.702G>A; p.K234K; 16:55485647-55485647	prostate	adenoma	Substitution - coding silent
c.1806C>T; p.F602F; 16:55502815-55502815	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.606G>A; p.G202G; 16:55485375-55485375	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.257C>G; p.T86R; 16:55483012-55483012	thyroid	carcinoma	Substitution - Missense
c.1947G>T; p.K649N; 16:55505406-55505406	urinary_tract; bladder	carcinoma	Substitution - Missense
c.850G>T; p.G284C; 16:55488560-55488560	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.47C>T; p.A16V; 16:55479526-55479526	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1111G>A; p.G371R; 16:55489755-55489755	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.288C>A; p.T96T; 16:55483043-55483043	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.259G>T; p.G87C; 16:55483014-55483014	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1573G>A; p.E525K; 16:55497026-55497026	skin	malignant_melanoma	Substitution - Missense
c.78_80delCGC; p.A30delA; 16:55479557-55479559	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - In frame
c.1144G>A; p.D382N; 16:55489788-55489788	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1144G>A; p.D382N; 16:55489788-55489788	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1498C>A; p.R500S; 16:55496951-55496951	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.789C>A; p.Y263*; 16:55485734-55485734	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.682G>A; p.A228T; 16:55485627-55485627	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.258A>C; p.T86T; 16:55483013-55483013	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.577C>T; p.H193Y; 16:55485346-55485346	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1133C>A; p.T378K; 16:55489777-55489777	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1541C>T; p.P514L; 16:55496994-55496994	skin	malignant_melanoma	Substitution - Missense
c.1610G>A; p.G537E; 16:55498289-55498289	skin	malignant_melanoma	Substitution - Missense
c.801G>C; p.K267N; 16:55485746-55485746	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.678G>C; p.G226G; 16:55485623-55485623	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.678G>C; p.G226G; 16:55485623-55485623	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.126C>T; p.A42A; 16:55479605-55479605	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1249C>T; p.P417S; 16:55491869-55491869	prostate	carcinoma	Substitution - Missense
c.867G>A; p.Q289Q; 16:55488577-55488577	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1181G>A; p.G394E; 16:55491801-55491801	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.134C>T; p.T45M; 16:55479613-55479613	stomach	adenocarcinoma	Substitution - Missense
c.1865A>G; p.D622G; 16:55502874-55502874	skin; shoulder	malignant_melanoma	Substitution - Missense
c.1388C>A; p.P463H; 16:55493209-55493209	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1116G>C; p.K372N; 16:55489760-55489760	breast	carcinoma	Substitution - Missense
c.1565C>T; p.A522V; 16:55497018-55497018	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1110C>T; p.D370D; 16:55489754-55489754	breast	carcinoma	Substitution - coding silent
c.1565C>T; p.A522V; 16:55497018-55497018	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1942G>A; p.V648M; 16:55505401-55505401	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1699C>A; p.R567R; 16:55498378-55498378	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1933C>G; p.L645V; 16:55505392-55505392	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1610G>C; p.G537A; 16:55498289-55498289	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1905C>T; p.A635A; 16:55505364-55505364	skin	malignant_melanoma	Substitution - coding silent
c.1444C>T; p.R482C; 16:55493265-55493265	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1042_1043CC>TT; p.P348F; 16:55489686-55489687	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1127C>T; p.A376V; 16:55489771-55489771	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1546C>G; p.L516V; 16:55496999-55496999	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1770-4A>G; p.?; 16:55502775-55502775	stomach	carcinoma; adenocarcinoma	Unknown
c.1169G>A; p.C390Y; 16:55489813-55489813	urinary_tract; bladder	carcinoma	Substitution - Missense
c.537C>T; p.G179G; 16:55485306-55485306	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1857C>G; p.A619A; 16:55502866-55502866	breast	carcinoma	Substitution - coding silent
c.905A>G; p.Y302C; 16:55488615-55488615	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.434C>T; p.A145V; 16:55484069-55484069	kidney	carcinoma; renal_cell_carcinoma	Substitution - Missense
c.717C>T; p.F239F; 16:55485662-55485662	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.468A>G; p.P156P; 16:55484103-55484103	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1167C>T; p.F389F; 16:55489811-55489811	skin	malignant_melanoma	Substitution - coding silent
c.658+3G>A; p.?; 16:55485430-55485430	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.207G>C; p.V69V; 16:55482962-55482962	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1134A>T; p.T378T; 16:55489778-55489778	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1454T>A; p.I485N; 16:55493275-55493275	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1777G>A; p.E593K; 16:55502786-55502786	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1221C>T; p.H407H; 16:55491841-55491841	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.565G>A; p.G189R; 16:55485334-55485334	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1219C>T; p.H407Y; 16:55491839-55491839	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.975C>T; p.R325R; 16:55488685-55488685	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.565G>A; p.G189R; 16:55485334-55485334	lung	carcinoma; bronchioloalveolar_adenocarcinoma	Substitution - Missense
c.555_574del20; p.G186fs*16; 16:55485324-55485343	breast	carcinoma	Deletion - Frameshift
c.896G>A; p.G299D; 16:55488606-55488606	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1354G>A; p.D452N; 16:55493175-55493175	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.855C>G; p.N285K; 16:55488565-55488565	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.970G>A; p.D324N; 16:55488680-55488680	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.524G>A; p.R175H; 16:55484159-55484159	urinary_tract; bladder	carcinoma	Substitution - Missense
c.524G>A; p.R175H; 16:55484159-55484159	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.969C>T; p.Y323Y; 16:55488679-55488679	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.815G>A; p.G272D; 16:55485760-55485760	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.978C>A; p.D326E; 16:55488688-55488688	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1559T>C; p.I520T; 16:55497012-55497012	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.117C>T; p.G39G; 16:55479596-55479596	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1302C>T; p.S434S; 16:55491922-55491922	skin	malignant_melanoma	Substitution - coding silent
c.1370_1371CC>TT; p.P457L; 16:55493191-55493192	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.662T>C; p.V221A; 16:55485607-55485607	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.661G>A; p.V221I; 16:55485606-55485606	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1098C>T; p.A366A; 16:55489742-55489742	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1647G>A; p.E549E; 16:55498326-55498326	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1686C>A; p.P562P; 16:55498365-55498365	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.1243C>A; p.Q415K; 16:55491863-55491863	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1429G>A; p.G477S; 16:55493250-55493250	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.963G>A; p.E321E; 16:55488673-55488673	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.556G>C; p.G186R; 16:55485325-55485325	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.928C>T; p.R310C; 16:55488638-55488638	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.928C>T; p.R310C; 16:55488638-55488638	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1100G>T; p.G367V; 16:55489744-55489744	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.694T>C; p.Y232H; 16:55485639-55485639	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.645G>A; p.L215L; 16:55485414-55485414	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1057T>G; p.F353V; 16:55489701-55489701	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1057T>G; p.F353V; 16:55489701-55489701	lung	carcinoma; adenocarcinoma	Substitution - Missense

The somatic mutations from COSMIC database