Entrez Gene

Basic Information
Gene ID	4303
Name	FOXO4

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.357G>T; p.E119D; 23:71096885-71096885	breast	carcinoma	Substitution - Missense
c.275G>A; p.R92Q; 23:71096803-71096803	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1006G>A; p.G336S; 23:71101236-71101236	oesophagus	carcinoma	Substitution - Missense
c.167delA; p.K57fs*32; 23:71096695-71096695	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.233G>A; p.G78E; 23:71096761-71096761	skin	malignant_melanoma	Substitution - Missense
c.483C>T; p.H161H; 23:71100713-71100713	lung	carcinoid-endocrine_tumour; typical	Substitution - coding silent
c.846G>T; p.A282A; 23:71101076-71101076	liver	carcinoma	Substitution - coding silent
c.1030T>C; p.S344P; 23:71101260-71101260	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.292C>T; p.R98W; 23:71096820-71096820	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.515C>T; p.T172I; 23:71100745-71100745	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.247G>A; p.G83R; 23:71096775-71096775	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.187C>T; p.R63C; 23:71096715-71096715	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.260C>T; p.A87V; 23:71096788-71096788	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.40G>A; p.A14T; 23:71096568-71096568	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1471A>G; p.M491V; 23:71101701-71101701	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.576_577CC>TA; p.R193S; 23:71100806-71100807	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1405G>T; p.D469Y; 23:71101635-71101635	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.336G>T; p.Q112H; 23:71096864-71096864	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.934C>G; p.L312V; 23:71101164-71101164	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1308A>C; p.P436P; 23:71101538-71101538	pancreas	carcinoid-endocrine_tumour	Substitution - coding silent
c.1093G>A; p.A365T; 23:71101323-71101323	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1141G>A; p.V381I; 23:71101371-71101371	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1141G>A; p.V381I; 23:71101371-71101371	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1141G>A; p.V381I; 23:71101371-71101371	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1141G>A; p.V381I; 23:71101371-71101371	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1181C>T; p.P394L; 23:71101411-71101411	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1094C>A; p.A365D; 23:71101324-71101324	bone; tibia	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.808C>A; p.R270R; 23:71101038-71101038	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.305G>A; p.G102E; 23:71096833-71096833	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1144C>T; p.L382F; 23:71101374-71101374	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.739C>T; p.R247C; 23:71100969-71100969	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1162_1163CC>AA; p.P388N; 23:71101392-71101393	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1230G>T; p.T410T; 23:71101460-71101460	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.972C>A; p.L324L; 23:71101202-71101202	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.748G>A; p.A250T; 23:71100978-71100978	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.650C>T; p.S217F; 23:71100880-71100880	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.132G>A; p.P44P; 23:71096660-71096660	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1230G>A; p.T410T; 23:71101460-71101460	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1337C>T; p.P446L; 23:71101567-71101567	skin	malignant_melanoma	Substitution - Missense
c.670G>A; p.E224K; 23:71100900-71100900	breast	carcinoma	Substitution - Missense
c.1359G>T; p.V453V; 23:71101589-71101589	pancreas	carcinoma	Substitution - coding silent
c.179C>T; p.T60M; 23:71096707-71096707	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.770G>A; p.R257H; 23:71101000-71101000	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.908G>T; p.G303V; 23:71101138-71101138	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.698G>A; p.G233D; 23:71100928-71100928	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.952C>T; p.L318L; 23:71101182-71101182	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.290G>A; p.R97H; 23:71096818-71096818	pancreas	carcinoma	Substitution - Missense
c.287C>T; p.S96F; 23:71096815-71096815	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.562_566delGGCAA; p.G188fs*11; 23:71100792-71100796	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.426T>A; p.G142G; 23:71096954-71096954	breast	carcinoma	Substitution - coding silent
c.623G>A; p.R208H; 23:71100853-71100853	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1288A>C; p.T430P; 23:71101518-71101518	breast	carcinoma	Substitution - Missense
c.1072G>T; p.G358W; 23:71101302-71101302	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.96C>T; p.T32T; 23:71096624-71096624	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.246C>T; p.P82P; 23:71096774-71096774	breast	carcinoma	Substitution - coding silent
c.1149G>T; p.M383I; 23:71101379-71101379	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.527C>G; p.S176C; 23:71100757-71100757	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.655C>A; p.L219M; 23:71100885-71100885	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.775C>T; p.R259*; 23:71101005-71101005	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.301T>A; p.W101R; 23:71096829-71096829	liver	carcinoma	Substitution - Missense
c.301T>A; p.W101R; 23:71096829-71096829	liver	carcinoma	Substitution - Missense
c.810G>A; p.R270R; 23:71101040-71101040	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1343C>A; p.A448D; 23:71101573-71101573	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.673G>A; p.G225S; 23:71100903-71100903	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1041C>A; p.S347R; 23:71101271-71101271	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.961C>T; p.R321W; 23:71101191-71101191	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.961C>T; p.R321W; 23:71101191-71101191	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.846G>A; p.A282A; 23:71101076-71101076	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.606C>A; p.S202R; 23:71100836-71100836	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1092G>A; p.Q364Q; 23:71101322-71101322	ovary	other; neoplasm	Substitution - coding silent
c.1299G>A; p.M433I; 23:71101529-71101529	breast	carcinoma	Substitution - Missense
c.639G>A; p.K213K; 23:71100869-71100869	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.398G>A; p.R133H; 23:71096926-71096926	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.575G>A; p.R192H; 23:71100805-71100805	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1195C>T; p.L399L; 23:71101425-71101425	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.569C>G; p.A190G; 23:71100799-71100799	liver	carcinoma	Substitution - Missense
c.569C>G; p.A190G; 23:71100799-71100799	liver	carcinoma	Substitution - Missense
c.272C>A; p.P91H; 23:71096800-71096800	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.765C>A; p.T255T; 23:71100995-71100995	pancreas	carcinoma	Substitution - coding silent
c.1236C>A; p.V412V; 23:71101466-71101466	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.298G>T; p.A100S; 23:71096826-71096826	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.745G>A; p.E249K; 23:71100975-71100975	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.595G>A; p.D199N; 23:71100825-71100825	liver	carcinoma	Substitution - Missense
c.1122G>A; p.T374T; 23:71101352-71101352	prostate	carcinoma	Substitution - coding silent
c.1110C>T; p.L370L; 23:71101340-71101340	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1129C>T; p.P377S; 23:71101359-71101359	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.327C>T; p.L109L; 23:71096855-71096855	breast	carcinoma	Substitution - coding silent
c.7C>G; p.P3A; 23:71096535-71096535	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1196_1197insG; p.L402fs*6; 23:71101426-71101427	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1196_1197insG; p.L402fs*6; 23:71101426-71101427	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1233C>T; p.G411G; 23:71101463-71101463	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1211C>T; p.S404F; 23:71101441-71101441	skin	malignant_melanoma	Substitution - Missense
c.347G>A; p.S116N; 23:71096875-71096875	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.966T>G; p.S322R; 23:71101196-71101196	breast	carcinoma	Substitution - Missense
c.674G>A; p.G225D; 23:71100904-71100904	kidney	other; neoplasm	Substitution - Missense

The somatic mutations from COSMIC database