Entrez Gene

Basic Information
Gene ID	4162
Name	MCAM

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.593C>T; p.S198L; 11:119312916-119312916	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1811G>C; p.R604P; 11:119310449-119310449	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - Missense
c.379C>T; p.R127C; 11:119314854-119314854	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.1119C>T; p.L373L; 11:119312076-119312076	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.576G>A; p.S192S; 11:119312933-119312933	breast	carcinoma	Substitution - coding silent
c.1638C>A; p.T546T; 11:119311097-119311097	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.594G>C; p.S198S; 11:119312915-119312915	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1917G>C; p.E639D; 11:119309910-119309910	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1800A>G; p.L600L; 11:119310460-119310460	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1800A>G; p.L600L; 11:119310460-119310460	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.1290C>T; p.P430P; 11:119311647-119311647	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1800A>G; p.L600L; 11:119310460-119310460	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.956A>G; p.E319G; 11:119312334-119312334	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.849C>A; p.S283R; 11:119312539-119312539	lung	carcinoid-endocrine_tumour; typical	Substitution - Missense
c.1707C>T; p.I569I; 11:119310842-119310842	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.933G>A; p.R311R; 11:119312357-119312357	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1217G>C; p.R406P; 11:119311876-119311876	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1377G>A; p.R459R; 11:119311560-119311560	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.906C>T; p.N302N; 11:119312384-119312384	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1867C>A; p.L623I; 11:119310393-119310393	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1867C>A; p.L623I; 11:119310393-119310393	large_intestine; colon	carcinoma	Substitution - Missense
c.1867C>A; p.L623I; 11:119310393-119310393	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.380G>A; p.R127H; 11:119314853-119314853	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1729G>A; p.A577T; 11:119310820-119310820	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.321C>T; p.T107T; 11:119314912-119314912	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1139A>G; p.E380G; 11:119312056-119312056	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.1147G>T; p.G383C; 11:119311946-119311946	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1147G>T; p.G383C; 11:119311946-119311946	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.730C>T; p.P244S; 11:119312779-119312779	skin; arm	malignant_melanoma	Substitution - Missense
c.609C>A; p.T203T; 11:119312900-119312900	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.800G>A; p.R267H; 11:119312588-119312588	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma; large_cell	Substitution - Missense
c.1646-1G>A; p.?; 11:119310904-119310904	urinary_tract; bladder	carcinoma	Unknown
c.800G>A; p.R267H; 11:119312588-119312588	central_nervous_system; medulla	primitive_neuroectodermal_tumour-medulloblastoma; large_cell	Substitution - Missense
c.800G>A; p.R267H; 11:119312588-119312588	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1425A>G; p.Q475Q; 11:119311404-119311404	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.484G>T; p.V162L; 11:119314564-119314564	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.777G>T; p.V259V; 11:119312611-119312611	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1245C>T; p.P415P; 11:119311848-119311848	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.559C>T; p.R187W; 11:119314489-119314489	pancreas	carcinoma	Substitution - Missense
c.368C>A; p.S123Y; 11:119314865-119314865	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1902G>A; p.P634P; 11:119310358-119310358	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1120G>A; p.E374K; 11:119312075-119312075	prostate	carcinoma	Substitution - Missense
c.1927G>A; p.D643N; 11:119309900-119309900	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1144-2A>T; p.?; 11:119311951-119311951	kidney	carcinoma; papillary_renal_cell_carcinoma	Unknown
c.1501G>T; p.A501S; 11:119311328-119311328	skin	malignant_melanoma	Substitution - Missense
c.1051G>T; p.A351S; 11:119312144-119312144	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.931C>T; p.R311W; 11:119312359-119312359	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1044G>A; p.V348V; 11:119312151-119312151	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.931C>T; p.R311W; 11:119312359-119312359	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.504C>T; p.P168P; 11:119314544-119314544	skin	malignant_melanoma	Substitution - coding silent
c.1756G>T; p.G586C; 11:119310793-119310793	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.1086C>T; p.T362T; 11:119312109-119312109	skin	malignant_melanoma	Substitution - coding silent
c.358C>T; p.R120C; 11:119314875-119314875	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1376G>A; p.R459Q; 11:119311561-119311561	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1881C>T; p.S627S; 11:119310379-119310379	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.658C>G; p.Q220E; 11:119312851-119312851	breast	carcinoma	Substitution - Missense
c.932G>A; p.R311Q; 11:119312358-119312358	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.932G>A; p.R311Q; 11:119312358-119312358	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.932G>A; p.R311Q; 11:119312358-119312358	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1080C>T; p.S360S; 11:119312115-119312115	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1318G>T; p.V440L; 11:119311619-119311619	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1216C>T; p.R406C; 11:119311877-119311877	prostate	carcinoma	Substitution - Missense
c.435C>T; p.P145P; 11:119314715-119314715	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.266A>G; p.E89G; 11:119314967-119314967	breast	carcinoma	Substitution - Missense
c.452A>G; p.N151S; 11:119314698-119314698	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.96G>A; p.A32A; 11:119315235-119315235	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.481T>C; p.C161R; 11:119314567-119314567	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1687G>C; p.V563L; 11:119310862-119310862	skin	malignant_melanoma	Substitution - Missense
c.799C>T; p.R267C; 11:119312589-119312589	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1398C>A; p.V466V; 11:119311539-119311539	breast	carcinoma	Substitution - coding silent
c.250G>A; p.E84K; 11:119314983-119314983	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1615C>T; p.P539S; 11:119311120-119311120	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1927G>T; p.D643Y; 11:119309900-119309900	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1663C>T; p.P555S; 11:119310886-119310886	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1426G>T; p.D476Y; 11:119311403-119311403	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.560G>A; p.R187Q; 11:119312949-119312949	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.212C>T; p.T71M; 11:119315021-119315021	stomach	adenocarcinoma	Substitution - Missense
c.212C>T; p.T71M; 11:119315021-119315021	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.496G>A; p.G166R; 11:119314552-119314552	breast	carcinoma	Substitution - Missense
c.559+2T>C; p.?; 11:119314487-119314487	liver	carcinoma	Unknown
c.1454A>G; p.N485S; 11:119311375-119311375	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.559+2T>C; p.?; 11:119314487-119314487	liver	carcinoma	Unknown
c.1012C>A; p.L338I; 11:119312278-119312278	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1794-2A>T; p.?; 11:119310468-119310468	breast	carcinoma	Unknown
c.330C>T; p.D110D; 11:119314903-119314903	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.802G>A; p.V268M; 11:119312586-119312586	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1234C>T; p.P412S; 11:119311859-119311859	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1819G>A; p.E607K; 11:119310441-119310441	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1819G>A; p.E607K; 11:119310441-119310441	breast	carcinoma	Substitution - Missense
c.1819G>A; p.E607K; 11:119310441-119310441	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1819G>A; p.E607K; 11:119310441-119310441	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.221T>G; p.F74C; 11:119315012-119315012	bone; tibia	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1486G>T; p.G496C; 11:119311343-119311343	skin	malignant_melanoma	Substitution - Missense
c.763G>A; p.E255K; 11:119312625-119312625	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1362G>A; p.A454A; 11:119311575-119311575	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.999T>G; p.S333R; 11:119312291-119312291	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1402G>A; p.G468S; 11:119311535-119311535	prostate	carcinoma	Substitution - Missense
c.1653G>A; p.K551K; 11:119310896-119310896	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1089G>A; p.L363L; 11:119312106-119312106	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1207G>A; p.G403S; 11:119311886-119311886	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1461C>T; p.L487L; 11:119311368-119311368	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.501C>A; p.Y167*; 11:119314547-119314547	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1375C>T; p.R459W; 11:119311562-119311562	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1672C>A; p.R558R; 11:119310877-119310877	breast	carcinoma	Substitution - coding silent
c.595A>T; p.S199C; 11:119312914-119312914	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.401-1G>T; p.?; 11:119314750-119314750	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Unknown
c.1029G>A; p.V343V; 11:119312166-119312166	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1816A>T; p.S606C; 11:119310444-119310444	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.949C>T; p.R317C; 11:119312341-119312341	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1148G>T; p.G383V; 11:119311945-119311945	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1883G>A; p.S628N; 11:119310377-119310377	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense

The somatic mutations from COSMIC database