Entrez Gene

Basic Information
Gene ID	3952
Name	LEP

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.298G>A; p.D100N; 7:128254557-128254557	skin	malignant_melanoma	Substitution - Missense
c.84A>G; p.Q28Q; 7:128252102-128252102	skin	malignant_melanoma	Substitution - coding silent
c.437C>G; p.A146G; 7:128254696-128254696	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.28T>A; p.L10M; 7:128252046-128252046	skin	malignant_melanoma	Substitution - Missense
c.275G>A; p.R92K; 7:128254534-128254534	skin	malignant_melanoma	Substitution - Missense
c.4C>T; p.H2Y; 7:128252022-128252022	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.27C>A; p.F9L; 7:128252045-128252045	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.21C>T; p.C7C; 7:128252039-128252039	central_nervous_system; brain	glioma	Substitution - coding silent
c.313C>A; p.R105R; 7:128254572-128254572	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.240A>G; p.A80A; 7:128254499-128254499	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.240A>G; p.A80A; 7:128254499-128254499	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.326A>T; p.H109L; 7:128254585-128254585	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.22G>A; p.G8R; 7:128252040-128252040	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.22G>A; p.G8R; 7:128252040-128252040	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.227A>C; p.D76A; 7:128254486-128254486	breast	carcinoma	Substitution - Missense
c.279C>T; p.N93N; 7:128254538-128254538	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.279C>T; p.N93N; 7:128254538-128254538	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.365C>T; p.A122V; 7:128254624-128254624	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.378G>A; p.E126E; 7:128254637-128254637	skin	malignant_melanoma	Substitution - coding silent
c.69C>T; p.P23P; 7:128252087-128252087	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.496G>T; p.G166W; 7:128254755-128254755	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.345G>A; p.K115K; 7:128254604-128254604	skin	malignant_melanoma	Substitution - coding silent
c.172A>G; p.T58A; 7:128254431-128254431	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.148T>A; p.S50T; 7:128254407-128254407	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.465G>A; p.Q155Q; 7:128254724-128254724	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.389G>A; p.S130N; 7:128254648-128254648	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.382T>G; p.L128V; 7:128254641-128254641	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.327C>A; p.H109Q; 7:128254586-128254586	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.408A>T; p.E136D; 7:128254667-128254667	liver	carcinoma	Substitution - Missense
c.408A>T; p.E136D; 7:128254667-128254667	liver	carcinoma	Substitution - Missense
c.497G>T; p.G166V; 7:128254756-128254756	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.472C>T; p.L158L; 7:128254731-128254731	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.34C>A; p.L12I; 7:128252052-128252052	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.385G>A; p.D129N; 7:128254644-128254644	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.370G>A; p.G124S; 7:128254629-128254629	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.432G>A; p.V144V; 7:128254691-128254691	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.303G>A; p.L101L; 7:128254562-128254562	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.333G>T; p.L111L; 7:128254592-128254592	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.402C>T; p.V134V; 7:128254661-128254661	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent

The somatic mutations from COSMIC database