Entrez Gene

Basic Information
Gene ID	3880
Name	KRT19

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.345G>A; p.W115*; 17:41527903-41527903	skin	malignant_melanoma	Substitution - Nonsense
c.1000C>T; p.Q334*; 17:41523946-41523946	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.1106T>C; p.I369T; 17:41523840-41523840	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1063G>A; p.D355N; 17:41523883-41523883	breast	carcinoma	Substitution - Missense
c.780C>T; p.A260A; 17:41524421-41524421	skin	malignant_melanoma	Substitution - coding silent
c.1153G>A; p.E385K; 17:41523793-41523793	skin	malignant_melanoma	Substitution - Missense
c.1122G>T; p.E374D; 17:41523824-41523824	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.423_424TC>TA; p.I141>?; 17:41525270-41525271	lung	carcinoma; adenocarcinoma	Complex
c.902G>A; p.R301H; 17:41524189-41524189	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.180delC; p.Y61fs*9; 17:41528068-41528068	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.180delC; p.Y61fs*9; 17:41528068-41528068	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.180delC; p.Y61fs*9; 17:41528068-41528068	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.497G>A; p.R166Q; 17:41525197-41525197	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.182A>G; p.Y61C; 17:41528066-41528066	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.497G>A; p.R166Q; 17:41525197-41525197	breast	carcinoma	Substitution - Missense
c.266A>T; p.D89V; 17:41527982-41527982	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.609G>T; p.Q203H; 17:41524894-41524894	liver	carcinoma	Substitution - Missense
c.609G>T; p.Q203H; 17:41524894-41524894	liver	carcinoma	Substitution - Missense
c.1143C>T; p.R381R; 17:41523803-41523803	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.512C>T; p.T171M; 17:41524991-41524991	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.512C>T; p.T171M; 17:41524991-41524991	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.512C>T; p.T171M; 17:41524991-41524991	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.11A>T; p.Y4F; 17:41528237-41528237	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.552C>T; p.N184N; 17:41524951-41524951	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.11A>T; p.Y4F; 17:41528237-41528237	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.744C>T; p.I248I; 17:41524457-41524457	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.179C>G; p.A60G; 17:41528069-41528069	thyroid	other; neoplasm	Substitution - Missense
c.319G>T; p.E107*; 17:41527929-41527929	breast	carcinoma	Substitution - Nonsense
c.179C>G; p.A60G; 17:41528069-41528069	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.179C>G; p.A60G; 17:41528069-41528069	thyroid	other; neoplasm	Substitution - Missense
c.573T>C; p.D191D; 17:41524930-41524930	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.355C>A; p.Q119K; 17:41527893-41527893	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.148G>T; p.A50S; 17:41528100-41528100	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.964G>C; p.D322H; 17:41523982-41523982	breast	carcinoma	Substitution - Missense
c.582_612del31; p.L195fs*3; 17:41524891-41524921	breast	carcinoma	Deletion - Frameshift
c.729C>T; p.T243T; 17:41524472-41524472	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.180_191del12; p.G64_G67delGYGG; 17:41528057-41528068	lung	carcinoma; adenocarcinoma	Deletion - In frame
c.63C>T; p.G21G; 17:41528185-41528185	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.379T>C; p.Y127H; 17:41527869-41527869	urinary_tract; bladder	carcinoma	Substitution - Missense
c.379T>C; p.Y127H; 17:41527869-41527869	urinary_tract; bladder	carcinoma	Substitution - Missense
c.771G>A; p.E257E; 17:41524430-41524430	skin	malignant_melanoma	Substitution - coding silent
c.1103A>T; p.D368V; 17:41523843-41523843	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.380A>C; p.Y127S; 17:41527868-41527868	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.380A>C; p.Y127S; 17:41527868-41527868	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1134_1135insC; p.T379fs*>23; 17:41523811-41523812	lung	carcinoma; adenocarcinoma	Insertion - Frameshift
c.153C>A; p.R51R; 17:41528095-41528095	prostate	carcinoma	Substitution - coding silent
c.650A>T; p.N217I; 17:41524853-41524853	prostate	carcinoma	Substitution - Missense
c.495C>T; p.F165F; 17:41525199-41525199	skin	malignant_melanoma	Substitution - coding silent
c.752A>G; p.D251G; 17:41524449-41524449	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.797A>T; p.D266V; 17:41524404-41524404	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.1066A>G; p.S356G; 17:41523880-41523880	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.980C>G; p.T327R; 17:41523966-41523966	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.689G>A; p.G230E; 17:41524512-41524512	skin	malignant_melanoma	Substitution - Missense
c.736G>A; p.A246T; 17:41524465-41524465	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.736G>A; p.A246T; 17:41524465-41524465	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.784C>T; p.Q262*; 17:41524417-41524417	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.730G>A; p.D244N; 17:41524471-41524471	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.730G>A; p.D244N; 17:41524471-41524471	liver	carcinoma	Substitution - Missense
c.730G>A; p.D244N; 17:41524471-41524471	liver	carcinoma	Substitution - Missense
c.1121A>G; p.E374G; 17:41523825-41523825	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.913_914GG>AA; p.G305N; 17:41524177-41524178	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.757C>T; p.R253*; 17:41524444-41524444	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.612_613insC; p.E205fs*15; 17:41524890-41524891	breast	carcinoma	Insertion - Frameshift
c.1015C>T; p.Q339*; 17:41523931-41523931	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.556C>A; p.L186M; 17:41524947-41524947	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.377A>C; p.D126A; 17:41527871-41527871	urinary_tract; bladder	carcinoma	Substitution - Missense
c.87C>T; p.V29V; 17:41528161-41528161	skin	malignant_melanoma	Substitution - coding silent
c.677G>T; p.R226M; 17:41524524-41524524	central_nervous_system; brain	atypical_teratoid-rhabdoid_tumour	Substitution - Missense
c.70C>G; p.R24G; 17:41528178-41528178	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.721C>A; p.P241T; 17:41524480-41524480	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.276C>T; p.A92A; 17:41527972-41527972	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.968C>A; p.T323K; 17:41523978-41523978	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.90C>T; p.A30A; 17:41528158-41528158	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.90C>T; p.A30A; 17:41528158-41528158	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.90C>T; p.A30A; 17:41528158-41528158	thyroid	other; neoplasm	Substitution - coding silent
c.90C>T; p.A30A; 17:41528158-41528158	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.90C>T; p.A30A; 17:41528158-41528158	breast	carcinoma	Substitution - coding silent
c.90C>T; p.A30A; 17:41528158-41528158	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.90C>T; p.A30A; 17:41528158-41528158	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.90C>T; p.A30A; 17:41528158-41528158	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.90C>T; p.A30A; 17:41528158-41528158	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.90C>T; p.A30A; 17:41528158-41528158	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.90C>T; p.A30A; 17:41528158-41528158	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.90C>T; p.A30A; 17:41528158-41528158	large_intestine; rectum	NS	Substitution - coding silent
c.90C>T; p.A30A; 17:41528158-41528158	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.588C>G; p.A196A; 17:41524915-41524915	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1109A>G; p.K370R; 17:41523837-41523837	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1073G>A; p.R358Q; 17:41523873-41523873	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1073G>A; p.R358Q; 17:41523873-41523873	breast	carcinoma	Substitution - Missense
c.894C>A; p.D298E; 17:41524197-41524197	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1105A>G; p.I369V; 17:41523841-41523841	pancreas	carcinoma	Substitution - Missense
c.216C>T; p.S72S; 17:41528032-41528032	skin	malignant_melanoma	Substitution - coding silent
c.1198C>T; p.L400F; 17:41523748-41523748	skin	malignant_melanoma	Substitution - Missense
c.735C>T; p.L245L; 17:41524466-41524466	breast	carcinoma	Substitution - coding silent
c.178G>T; p.A60S; 17:41528070-41528070	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense

The somatic mutations from COSMIC database