Entrez Gene

Basic Information
Gene ID	3714
Name	JAG2

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.3476G>A; p.R1159H; 14:105142936-105142936	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3476G>A; p.R1159H; 14:105142936-105142936	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2001G>T; p.E667D; 14:105148764-105148764	skin; extremity	malignant_melanoma	Substitution - Missense
c.1670A>G; p.D557G; 14:105149253-105149253	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1253C>T; p.A418V; 14:105151297-105151297	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2038C>T; p.P680S; 14:105148422-105148422	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.669C>T; p.C223C; 14:105155796-105155796	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1501G>A; p.E501K; 14:105150705-105150705	breast	carcinoma	Substitution - Missense
c.619T>C; p.C207R; 14:105155846-105155846	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1294T>C; p.C432R; 14:105151078-105151078	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1124C>T; p.S375L; 14:105151655-105151655	breast	carcinoma	Substitution - Missense
c.398_399CC>TT; p.P133L; 14:105167775-105167776	skin; trunk	malignant_melanoma	Substitution - Missense
c.1726G>A; p.E576K; 14:105149197-105149197	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2479+2T>C; p.?; 14:105147324-105147324	stomach	carcinoma; intestinal_adenocarcinoma	Unknown
c.3163C>T; p.Q1055*; 14:105143560-105143560	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1612G>A; p.D538N; 14:105149311-105149311	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1612G>A; p.D538N; 14:105149311-105149311	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; primary_central_nervous_system_lymphoma	Substitution - Missense
c.1612G>A; p.D538N; 14:105149311-105149311	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1612G>A; p.D538N; 14:105149311-105149311	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1612G>A; p.D538N; 14:105149311-105149311	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1612G>A; p.D538N; 14:105149311-105149311	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1612G>A; p.D538N; 14:105149311-105149311	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1612G>A; p.D538N; 14:105149311-105149311	thyroid	other; neoplasm	Substitution - Missense
c.2598C>T; p.I866I; 14:105146496-105146496	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2598C>T; p.I866I; 14:105146496-105146496	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1725C>G; p.R575R; 14:105149198-105149198	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.1179G>A; p.P393P; 14:105151371-105151371	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.830T>C; p.V277A; 14:105152250-105152250	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1899C>T; p.C633C; 14:105148944-105148944	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3520G>A; p.V1174I; 14:105142892-105142892	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2848G>A; p.G950S; 14:105145835-105145835	pancreas	carcinoma	Substitution - Missense
c.2273A>G; p.N758S; 14:105147864-105147864	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3627G>A; p.P1209P; 14:105142785-105142785	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3627G>A; p.P1209P; 14:105142785-105142785	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.439G>T; p.E147*; 14:105157742-105157742	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.744G>A; p.G248G; 14:105155606-105155606	skin; head_neck	malignant_melanoma; superficial_spreading	Substitution - coding silent
c.1444T>C; p.Y482H; 14:105150762-105150762	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2915G>A; p.R972H; 14:105145768-105145768	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.598G>A; p.E200K; 14:105155867-105155867	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2337C>T; p.D779D; 14:105147800-105147800	pancreas	carcinoma	Substitution - coding silent
c.1968C>T; p.D656D; 14:105148797-105148797	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.577C>T; p.Q193*; 14:105155888-105155888	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2395T>C; p.Y799H; 14:105147410-105147410	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.563C>T; p.A188V; 14:105155902-105155902	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.1418delG; p.G473fs*7; 14:105150875-105150875	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3680G>A; p.R1227K; 14:105142732-105142732	skin	malignant_melanoma	Substitution - Missense
c.783G>A; p.E261E; 14:105155567-105155567	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.2695C>T; p.R899C; 14:105146399-105146399	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2221G>A; p.G741S; 14:105148143-105148143	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.422C>T; p.S141F; 14:105157759-105157759	skin	malignant_melanoma	Substitution - Missense
c.1495C>T; p.R499*; 14:105150711-105150711	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.900C>T; p.G300G; 14:105152180-105152180	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2446G>A; p.A816T; 14:105147359-105147359	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1178C>T; p.P393L; 14:105151372-105151372	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2435G>A; p.R812H; 14:105147370-105147370	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3069T>C; p.A1023A; 14:105144945-105144945	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3069T>C; p.A1023A; 14:105144945-105144945	thyroid	other; neoplasm	Substitution - coding silent
c.3069T>C; p.A1023A; 14:105144945-105144945	thyroid	other; neoplasm	Substitution - coding silent
c.2547T>G; p.Y849*; 14:105146657-105146657	skin	malignant_melanoma	Substitution - Nonsense
c.418C>T; p.R140C; 14:105157763-105157763	pancreas	carcinoma	Substitution - Missense
c.1767C>T; p.C589C; 14:105149076-105149076	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1648C>T; p.R550C; 14:105149275-105149275	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2127C>T; p.C709C; 14:105148333-105148333	breast	carcinoma	Substitution - coding silent
c.1389C>T; p.N463N; 14:105150904-105150904	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2221_2222insC; p.G741fs*66; 14:105148142-105148143	stomach	carcinoma; intestinal_adenocarcinoma	Insertion - Frameshift
c.3265G>T; p.G1089C; 14:105143147-105143147	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1204G>A; p.D402N; 14:105151346-105151346	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.3418C>T; p.R1140W; 14:105142994-105142994	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.157G>A; p.D53N; 14:105168017-105168017	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1149C>T; p.A383A; 14:105151630-105151630	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.182delG; p.G61fs*22; 14:105167992-105167992	pancreas	carcinoma; acinar_carcinoma	Deletion - Frameshift
c.2522C>T; p.T841M; 14:105146682-105146682	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.91G>A; p.E31K; 14:105168083-105168083	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.979G>A; p.E327K; 14:105151998-105151998	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1173G>A; p.S391S; 14:105151377-105151377	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1173G>A; p.S391S; 14:105151377-105151377	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.710G>A; p.G237D; 14:105155755-105155755	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2122A>C; p.T708P; 14:105148338-105148338	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2057G>A; p.R686H; 14:105148403-105148403	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - Missense
c.1172C>T; p.S391L; 14:105151378-105151378	skin	malignant_melanoma	Substitution - Missense
c.1740C>T; p.G580G; 14:105149183-105149183	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - coding silent
c.2122A>C; p.T708P; 14:105148338-105148338	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2122A>C; p.T708P; 14:105148338-105148338	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1172C>T; p.S391L; 14:105151378-105151378	skin	malignant_melanoma	Substitution - Missense
c.2986C>A; p.R996S; 14:105145028-105145028	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2122A>C; p.T708P; 14:105148338-105148338	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2044C>T; p.P682S; 14:105148416-105148416	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2220delC; p.G741fs*21; 14:105148144-105148144	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2487C>T; p.D829D; 14:105146717-105146717	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3325C>T; p.R1109C; 14:105143087-105143087	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.477G>T; p.E159D; 14:105155988-105155988	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2644G>T; p.G882*; 14:105146450-105146450	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3604A>G; p.T1202A; 14:105142808-105142808	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3604A>G; p.T1202A; 14:105142808-105142808	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.585C>T; p.R195R; 14:105155880-105155880	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1835G>A; p.C612Y; 14:105149008-105149008	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.340C>A; p.R114R; 14:105167834-105167834	liver	carcinoma	Substitution - coding silent
c.340C>A; p.R114R; 14:105167834-105167834	liver	carcinoma	Substitution - coding silent
c.2733T>C; p.C911C; 14:105145950-105145950	skin	malignant_melanoma	Substitution - coding silent
c.909C>T; p.L303L; 14:105152171-105152171	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.739C>T; p.Q247*; 14:105155611-105155611	meninges	meningioma	Substitution - Nonsense
c.2298C>T; p.C766C; 14:105147839-105147839	liver	carcinoma	Substitution - coding silent
c.2298C>T; p.C766C; 14:105147839-105147839	liver	carcinoma	Substitution - coding silent
c.3646G>A; p.A1216T; 14:105142766-105142766	liver	carcinoma	Substitution - Missense
c.2677C>T; p.R893C; 14:105146417-105146417	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2980G>C; p.G994R; 14:105145034-105145034	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3464C>T; p.T1155M; 14:105142948-105142948	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1097C>T; p.P366L; 14:105151682-105151682	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1842C>T; p.S614S; 14:105149001-105149001	skin	malignant_melanoma	Substitution - coding silent
c.3249G>C; p.L1083L; 14:105143163-105143163	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.2170G>A; p.G724S; 14:105148194-105148194	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2583G>C; p.R861R; 14:105146621-105146621	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.957C>T; p.N319N; 14:105152020-105152020	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3712G>A; p.E1238K; 14:105142700-105142700	skin	malignant_melanoma	Substitution - Missense
c.3674C>T; p.A1225V; 14:105142738-105142738	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2623C>T; p.R875W; 14:105146471-105146471	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1012G>T; p.G338C; 14:105151965-105151965	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2978C>G; p.S993C; 14:105145036-105145036	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1390G>A; p.D464N; 14:105150903-105150903	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2692C>T; p.R898C; 14:105146402-105146402	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2935C>T; p.R979C; 14:105145748-105145748	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2122A>G; p.T708A; 14:105148338-105148338	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1075G>A; p.G359R; 14:105151704-105151704	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2632C>T; p.P878S; 14:105146462-105146462	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2886C>A; p.R962R; 14:105145797-105145797	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1052G>A; p.C351Y; 14:105151727-105151727	central_nervous_system; brain	glioma; astrocytoma_Grade_II	Substitution - Missense
c.1456_1457delTG; p.C486fs*48; 14:105150749-105150750	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3537G>T; p.E1179D; 14:105142875-105142875	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2968G>A; p.A990T; 14:105145046-105145046	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.786C>T; p.C262C; 14:105155564-105155564	thyroid	other; neoplasm	Substitution - coding silent
c.3430C>T; p.H1144Y; 14:105142982-105142982	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2550C>A; p.R850R; 14:105146654-105146654	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1397G>A; p.R466H; 14:105150896-105150896	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1641delC; p.N547fs*39; 14:105149282-105149282	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.3270C>T; p.A1090A; 14:105143142-105143142	skin	malignant_melanoma	Substitution - coding silent
c.597C>T; p.D199D; 14:105155868-105155868	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - coding silent
c.594C>T; p.C198C; 14:105155871-105155871	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2455T>A; p.F819I; 14:105147350-105147350	pancreas	carcinoma	Substitution - Missense
c.3656C>T; p.P1219L; 14:105142756-105142756	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.182_183insG; p.C62fs*15; 14:105167991-105167992	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.3707G>A; p.G1236D; 14:105142705-105142705	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2599G>A; p.G867R; 14:105146495-105146495	skin	malignant_melanoma	Substitution - Missense
c.613G>A; p.A205T; 14:105155852-105155852	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.613G>A; p.A205T; 14:105155852-105155852	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.522G>A; p.P174P; 14:105155943-105155943	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.3142G>A; p.A1048T; 14:105143581-105143581	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3142G>A; p.A1048T; 14:105143581-105143581	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1649G>T; p.R550L; 14:105149274-105149274	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1851G>A; p.G617G; 14:105148992-105148992	skin	malignant_melanoma	Substitution - coding silent
c.1649G>A; p.R550H; 14:105149274-105149274	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3319C>T; p.R1107C; 14:105143093-105143093	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2869A>C; p.T957P; 14:105145814-105145814	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2998G>T; p.A1000S; 14:105145016-105145016	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.2869A>C; p.T957P; 14:105145814-105145814	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2869A>C; p.T957P; 14:105145814-105145814	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2869A>C; p.T957P; 14:105145814-105145814	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2869A>C; p.T957P; 14:105145814-105145814	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2382C>A; p.N794K; 14:105147511-105147511	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.646G>A; p.D216N; 14:105155819-105155819	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.646G>A; p.D216N; 14:105155819-105155819	skin	malignant_melanoma	Substitution - Missense
c.1022G>C; p.G341A; 14:105151955-105151955	skin	malignant_melanoma	Substitution - Missense
c.1056C>T; p.T352T; 14:105151723-105151723	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.2106C>T; p.D702D; 14:105148354-105148354	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.770C>T; p.T257I; 14:105155580-105155580	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.958G>A; p.G320R; 14:105152019-105152019	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.770C>T; p.T257I; 14:105155580-105155580	skin	malignant_melanoma	Substitution - Missense
c.3143C>T; p.A1048V; 14:105143580-105143580	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3414T>C; p.I1138I; 14:105142998-105142998	thyroid	other; neoplasm	Substitution - coding silent
c.3414T>C; p.I1138I; 14:105142998-105142998	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2936G>A; p.R979H; 14:105145747-105145747	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3414T>C; p.I1138I; 14:105142998-105142998	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3414T>C; p.I1138I; 14:105142998-105142998	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3414T>C; p.I1138I; 14:105142998-105142998	thyroid	other; neoplasm	Substitution - coding silent
c.3414T>C; p.I1138I; 14:105142998-105142998	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2134+1G>T; p.?; 14:105148325-105148325	lung	carcinoma; adenocarcinoma	Unknown
c.1681G>T; p.A561S; 14:105149242-105149242	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1681G>T; p.A561S; 14:105149242-105149242	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.688G>T; p.A230S; 14:105155777-105155777	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1072A>T; p.N358Y; 14:105151707-105151707	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.3577G>A; p.A1193T; 14:105142835-105142835	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1931C>T; p.P644L; 14:105148834-105148834	skin	malignant_melanoma	Substitution - Missense
c.3499G>A; p.G1167R; 14:105142913-105142913	liver	carcinoma	Substitution - Missense
c.1641C>T; p.N547N; 14:105149282-105149282	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1690G>A; p.D564N; 14:105149233-105149233	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1680C>T; p.C560C; 14:105149243-105149243	breast	carcinoma	Substitution - coding silent
c.1134C>T; p.S378S; 14:105151645-105151645	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1641C>T; p.N547N; 14:105149282-105149282	central_nervous_system; brain	glioma	Substitution - coding silent
c.462T>A; p.D154E; 14:105157719-105157719	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1260C>T; p.C420C; 14:105151290-105151290	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2335G>T; p.D779Y; 14:105147802-105147802	pancreas	carcinoid-endocrine_tumour	Substitution - Missense
c.3301C>A; p.L1101M; 14:105143111-105143111	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2921C>A; p.T974N; 14:105145762-105145762	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1774G>T; p.D592Y; 14:105149069-105149069	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.3274A>G; p.S1092G; 14:105143138-105143138	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2268G>T; p.L756L; 14:105147869-105147869	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2097G>A; p.A699A; 14:105148363-105148363	liver	carcinoma	Substitution - coding silent
c.2097G>A; p.A699A; 14:105148363-105148363	liver	carcinoma	Substitution - coding silent

The somatic mutations from COSMIC database