Entrez Gene

Basic Information
Gene ID	3688
Name	ITGB1

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.472G>A; p.D158N; 10:32928169-32928169	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.471C>T; p.D157D; 10:32928170-32928170	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1483C>A; p.R495S; 10:32912111-32912111	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.364C>T; p.R122*; 10:32929834-32929834	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2475G>A; p.P825P; 10:32901608-32901608	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1433A>G; p.H478R; 10:32919921-32919921	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1776T>C; p.C592C; 10:32911603-32911603	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1593C>T; p.C531C; 10:32912001-32912001	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.991A>T; p.I331F; 10:32922687-32922687	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.1461C>T; p.G487G; 10:32919893-32919893	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1594G>A; p.V532I; 10:32912000-32912000	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2448-4G>T; p.?; 10:32901639-32901639	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.2018T>C; p.V673A; 10:32910369-32910369	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1282A>G; p.I428V; 10:32920072-32920072	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1469G>A; p.R490K; 10:32919885-32919885	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1839C>T; p.C613C; 10:32911540-32911540	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1839C>T; p.C613C; 10:32911540-32911540	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1496A>T; p.H499L; 10:32912098-32912098	skin	malignant_melanoma	Substitution - Missense
c.1975G>C; p.D659H; 10:32910412-32910412	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.451C>T; p.L151L; 10:32928190-32928190	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1483C>T; p.R495C; 10:32912111-32912111	breast	carcinoma	Substitution - Missense
c.2293A>G; p.K765E; 10:32908406-32908406	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1722C>T; p.C574C; 10:32911657-32911657	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1889G>A; p.C630Y; 10:32911490-32911490	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.824T>G; p.V275G; 10:32923703-32923703	breast	carcinoma	Substitution - Missense
c.717G>A; p.Q239Q; 10:32925940-32925940	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.581C>G; p.P194R; 10:32926076-32926076	thyroid	carcinoma	Substitution - Missense
c.1836C>G; p.I612M; 10:32911543-32911543	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2000A>G; p.Y667C; 10:32910387-32910387	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.955A>G; p.I319V; 10:32922723-32922723	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1810G>A; p.G604R; 10:32911569-32911569	stomach	adenocarcinoma	Substitution - Missense
c.793A>G; p.I265V; 10:32923734-32923734	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1843T>C; p.C615R; 10:32911536-32911536	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.724T>A; p.S242T; 10:32925933-32925933	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.292C>T; p.R98C; 10:32929906-32929906	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.783T>C; p.C261C; 10:32925874-32925874	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3G>C; p.M1I; 10:32935556-32935556	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.445A>G; p.M149V; 10:32928196-32928196	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1409G>A; p.G470D; 10:32919945-32919945	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.445A>C; p.M149L; 10:32928196-32928196	breast	carcinoma	Substitution - Missense
c.488A>C; p.K163T; 10:32928153-32928153	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1209C>T; p.N403N; 10:32920305-32920305	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1209C>T; p.N403N; 10:32920305-32920305	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1147A>T; p.I383F; 10:32920367-32920367	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.1209C>T; p.N403N; 10:32920305-32920305	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1209C>T; p.N403N; 10:32920305-32920305	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.270G>T; p.K90N; 10:32929928-32929928	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.270G>T; p.K90N; 10:32929928-32929928	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1132C>A; p.L378I; 10:32920382-32920382	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1132C>A; p.L378I; 10:32920382-32920382	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1132C>A; p.L378I; 10:32920382-32920382	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1132C>A; p.L378I; 10:32920382-32920382	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1469+1G>A; p.?; 10:32919884-32919884	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.285A>G; p.V95V; 10:32929913-32929913	breast	carcinoma	Substitution - coding silent
c.2092G>A; p.D698N; 10:32910295-32910295	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2112G>A; p.T704T; 10:32910275-32910275	liver	carcinoma	Substitution - coding silent
c.2112G>A; p.T704T; 10:32910275-32910275	liver	carcinoma	Substitution - coding silent
c.135T>C; p.C45C; 10:32932533-32932533	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.34A>C; p.I12L; 10:32935525-32935525	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1416T>C; p.P472P; 10:32919938-32919938	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.2457C>T; p.I819I; 10:32901626-32901626	skin	malignant_melanoma	Substitution - coding silent
c.1055T>C; p.I352T; 10:32922330-32922330	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.373T>A; p.S125T; 10:32929825-32929825	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.1419A>T; p.E473D; 10:32919935-32919935	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.702A>G; p.E234E; 10:32925955-32925955	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2310A>C; p.K770N; 10:32908389-32908389	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1123T>G; p.Y375D; 10:32922262-32922262	liver	carcinoma	Substitution - Missense
c.2231G>A; p.G744D; 10:32908468-32908468	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1041G>T; p.E347D; 10:32922344-32922344	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2266A>T; p.I756L; 10:32908433-32908433	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.963C>T; p.H321H; 10:32922715-32922715	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1313delA; p.K438fs*17; 10:32920041-32920041	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1225G>T; p.G409W; 10:32920289-32920289	pancreas	carcinoma	Substitution - Missense
c.1985C>T; p.T662I; 10:32910402-32910402	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.266T>C; p.I89T; 10:32929932-32929932	pancreas	carcinoma	Substitution - Missense
c.1506C>T; p.C502C; 10:32912088-32912088	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2224C>A; p.L742I; 10:32908475-32908475	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2194A>C; p.I732L; 10:32908505-32908505	liver	carcinoma	Substitution - Missense
c.2330C>T; p.T777M; 10:32908369-32908369	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2330C>T; p.T777M; 10:32908369-32908369	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2194A>C; p.I732L; 10:32908505-32908505	liver	carcinoma	Substitution - Missense
c.384A>G; p.P128P; 10:32928257-32928257	breast	carcinoma	Substitution - coding silent
c.1484G>A; p.R495H; 10:32912110-32912110	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.929T>C; p.M310T; 10:32923598-32923598	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1513G>C; p.D505H; 10:32912081-32912081	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1314G>T; p.K438N; 10:32920040-32920040	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2131A>G; p.N711D; 10:32910256-32910256	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.447G>T; p.M149I; 10:32928194-32928194	skin	malignant_melanoma	Substitution - Missense
c.1942C>T; p.Q648*; 10:32910445-32910445	breast	carcinoma	Substitution - Nonsense
c.756C>T; p.F252F; 10:32925901-32925901	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2050C>G; p.Q684E; 10:32910337-32910337	breast	carcinoma	Substitution - Missense
c.542G>A; p.R181K; 10:32928099-32928099	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1256C>T; p.S419F; 10:32920258-32920258	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1289T>C; p.I430T; 10:32920065-32920065	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1288A>G; p.I430V; 10:32920066-32920066	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1334T>A; p.I445N; 10:32920020-32920020	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1412T>A; p.I471N; 10:32919942-32919942	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2228T>C; p.I743T; 10:32908471-32908471	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1352C>T; p.T451M; 10:32920002-32920002	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.238A>G; p.I80V; 10:32929960-32929960	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.786+2T>C; p.?; 10:32925869-32925869	stomach	carcinoma; adenocarcinoma	Unknown
c.433C>T; p.L145F; 10:32928208-32928208	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1958A>G; p.N653S; 10:32910429-32910429	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1576A>G; p.S526G; 10:32912018-32912018	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.1749C>T; p.P583P; 10:32911630-32911630	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.656A>G; p.Y219C; 10:32926001-32926001	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.453G>T; p.L151L; 10:32928188-32928188	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1207A>G; p.N403D; 10:32920307-32920307	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1207A>G; p.N403D; 10:32920307-32920307	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.17T>G; p.I6S; 10:32935542-32935542	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.33G>A; p.L11L; 10:32935526-32935526	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1636G>A; p.E546K; 10:32911958-32911958	thyroid	carcinoma	Substitution - Missense
c.826T>C; p.F276L; 10:32923701-32923701	breast	carcinoma	Substitution - Missense
c.1160G>A; p.G387D; 10:32920354-32920354	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.178A>G; p.T60A; 10:32930020-32930020	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1110G>A; p.L370L; 10:32922275-32922275	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1730G>A; p.R577H; 10:32911649-32911649	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1158C>T; p.N386N; 10:32920356-32920356	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1086A>C; p.A362A; 10:32922299-32922299	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.260A>G; p.K87R; 10:32929938-32929938	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1596C>T; p.V532V; 10:32911998-32911998	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.719G>A; p.R240H; 10:32925938-32925938	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.327G>A; p.E109E; 10:32929871-32929871	skin	malignant_melanoma	Substitution - coding silent
c.942+7G>T; p.?; 10:32923578-32923578	kidney	other; neoplasm	Unknown
c.290A>G; p.N97S; 10:32929908-32929908	prostate	carcinoma	Substitution - Missense
c.490delA; p.S164fs*6; 10:32928151-32928151	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.877A>G; p.I293V; 10:32923650-32923650	central_nervous_system; brainstem	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1674C>T; p.F558F; 10:32911920-32911920	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent

The somatic mutations from COSMIC database