Entrez Gene

Basic Information
Gene ID	3673
Name	ITGA2

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.2487G>T; p.L829L; 5:53073175-53073175	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3046G>T; p.D1016Y; 5:53081598-53081598	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.54G>T; p.A18A; 5:52989522-52989522	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2620G>C; p.V874L; 5:53074433-53074433	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2767G>A; p.D923N; 5:53075246-53075246	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.954C>T; p.N318N; 5:53056007-53056007	liver	carcinoma	Substitution - coding silent
c.954C>T; p.N318N; 5:53056007-53056007	liver	carcinoma	Substitution - coding silent
c.2680A>G; p.N894D; 5:53075076-53075076	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1244G>A; p.G415D; 5:53059944-53059944	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2155G>T; p.E719*; 5:53070180-53070180	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3184T>C; p.L1062L; 5:53083379-53083379	skin	malignant_melanoma	Substitution - coding silent
c.1319C>G; p.S440C; 5:53060907-53060907	oesophagus	carcinoma	Substitution - Missense
c.2460C>T; p.N820N; 5:53073148-53073148	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.576G>T; p.K192N; 5:53048716-53048716	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.850G>A; p.G284S; 5:53055608-53055608	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; primary_central_nervous_system_lymphoma	Substitution - Missense
c.1920C>T; p.A640A; 5:53065954-53065954	skin	malignant_melanoma	Substitution - coding silent
c.576G>T; p.K192N; 5:53048716-53048716	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3107C>T; p.S1036F; 5:53081659-53081659	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1220C>T; p.T407I; 5:53059920-53059920	skin	malignant_melanoma	Substitution - Missense
c.759C>T; p.F253F; 5:53051539-53051539	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.3116G>A; p.S1039N; 5:53081668-53081668	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.3265T>C; p.F1089L; 5:53086958-53086958	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.263C>A; p.S88Y; 5:53042189-53042189	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1030G>T; p.V344L; 5:53056083-53056083	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1617G>A; p.Q539Q; 5:53064926-53064926	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1487G>C; p.C496S; 5:53062814-53062814	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1617G>A; p.Q539Q; 5:53064926-53064926	thyroid	carcinoma	Substitution - coding silent
c.825G>A; p.T275T; 5:53055583-53055583	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.825G>A; p.T275T; 5:53055583-53055583	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.825G>A; p.T275T; 5:53055583-53055583	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1903G>A; p.D635N; 5:53065937-53065937	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1903G>A; p.D635N; 5:53065937-53065937	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.512C>T; p.S171F; 5:53048652-53048652	skin	malignant_melanoma	Substitution - Missense
c.1421G>T; p.G474V; 5:53061009-53061009	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2129G>A; p.R710K; 5:53070154-53070154	skin; mucosal	malignant_melanoma	Substitution - Missense
c.1413T>C; p.N471N; 5:53061001-53061001	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1643G>A; p.G548D; 5:53064952-53064952	skin	malignant_melanoma	Substitution - Missense
c.388-1G>A; p.?; 5:53048362-53048362	skin	malignant_melanoma	Unknown
c.1685C>T; p.S562L; 5:53064994-53064994	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1685C>T; p.S562L; 5:53064994-53064994	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1253T>G; p.I418S; 5:53059953-53059953	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.835G>C; p.V279L; 5:53055593-53055593	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1838G>A; p.S613N; 5:53065872-53065872	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3161C>T; p.S1054F; 5:53083356-53083356	skin	malignant_melanoma	Substitution - Missense
c.1648G>T; p.E550*; 5:53064957-53064957	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.446G>A; p.C149Y; 5:53048421-53048421	stomach	carcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	Substitution - Missense
c.780-1G>T; p.?; 5:53055537-53055537	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.2650A>C; p.K884Q; 5:53074463-53074463	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3385G>A; p.E1129K; 5:53089982-53089982	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1863C>T; p.S621S; 5:53065897-53065897	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.296-10C>T; p.?; 5:53044991-53044991	skin; leg	malignant_melanoma	Unknown
c.927A>G; p.I309M; 5:53055685-53055685	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.296-10C>T; p.?; 5:53044991-53044991	skin; leg	malignant_melanoma	Unknown
c.2118_2119insT; p.S708fs*11; 5:53070143-53070144	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.2211C>T; p.C737C; 5:53070236-53070236	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - coding silent
c.1810A>C; p.I604L; 5:53065844-53065844	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1599+6delA; p.?; 5:53062932-53062932	central_nervous_system; thalamus	glioma; oligoastrocytoma_Grade_II	Unknown
c.2670T>A; p.T890T; 5:53075066-53075066	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1342G>C; p.E448Q; 5:53060930-53060930	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2530G>T; p.D844Y; 5:53073218-53073218	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1342G>C; p.E448Q; 5:53060930-53060930	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.2258C>T; p.S753F; 5:53071960-53071960	skin	malignant_melanoma	Substitution - Missense
c.1941C>T; p.L647L; 5:53065975-53065975	breast	carcinoma	Substitution - coding silent
c.1910C>T; p.S637F; 5:53065944-53065944	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2332G>T; p.A778S; 5:53072034-53072034	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.2919C>T; p.F973F; 5:53078865-53078865	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2629G>A; p.D877N; 5:53074442-53074442	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3482G>T; p.R1161I; 5:53090535-53090535	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.613G>C; p.G205R; 5:53048753-53048753	central_nervous_system; brain	atypical_teratoid-rhabdoid_tumour	Substitution - Missense
c.2792C>T; p.P931L; 5:53075271-53075271	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3252C>T; p.F1084F; 5:53083447-53083447	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.3252C>T; p.F1084F; 5:53083447-53083447	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1254C>T; p.I418I; 5:53059954-53059954	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.3086G>T; p.G1029V; 5:53081638-53081638	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2747G>T; p.S916I; 5:53075226-53075226	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1715T>A; p.V572E; 5:53065024-53065024	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1375G>A; p.A459T; 5:53060963-53060963	bone; rib	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.572T>A; p.V191E; 5:53048712-53048712	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1207G>T; p.G403C; 5:53059907-53059907	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1633G>A; p.G545S; 5:53064942-53064942	skin	malignant_melanoma	Substitution - Missense
c.1672A>C; p.I558L; 5:53064981-53064981	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1737A>G; p.E579E; 5:53065046-53065046	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.521A>C; p.D174A; 5:53048661-53048661	breast	carcinoma	Substitution - Missense
c.3535C>T; p.L1179F; 5:53090588-53090588	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.718T>A; p.S240T; 5:53051498-53051498	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.502+1G>A; p.?; 5:53048478-53048478	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.3389T>C; p.V1130A; 5:53089986-53089986	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1569G>T; p.E523D; 5:53062896-53062896	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2755G>A; p.E919K; 5:53075234-53075234	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2755G>A; p.E919K; 5:53075234-53075234	skin	malignant_melanoma	Substitution - Missense
c.3079A>G; p.K1027E; 5:53081631-53081631	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.2772T>A; p.N924K; 5:53075251-53075251	skin	malignant_melanoma	Substitution - Missense
c.1448G>A; p.R483Q; 5:53061036-53061036	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.437C>T; p.T146M; 5:53048412-53048412	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.679A>G; p.N227D; 5:53051459-53051459	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.2858C>T; p.S953L; 5:53078804-53078804	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2858C>T; p.S953L; 5:53078804-53078804	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.501G>A; p.Q167Q; 5:53048476-53048476	skin	malignant_melanoma	Substitution - coding silent
c.1258C>G; p.P420A; 5:53059958-53059958	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2959G>A; p.A987T; 5:53080541-53080541	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.697G>T; p.E233*; 5:53051477-53051477	autonomic_ganglia	neuroblastoma	Substitution - Nonsense
c.3193G>A; p.V1065I; 5:53083388-53083388	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2138C>G; p.S713C; 5:53070163-53070163	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.1612G>T; p.G538C; 5:53064921-53064921	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1292G>T; p.R431I; 5:53059992-53059992	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.955G>A; p.A319T; 5:53056008-53056008	liver	carcinoma	Substitution - Missense
c.1522G>T; p.V508L; 5:53062849-53062849	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2713C>G; p.Q905E; 5:53075109-53075109	breast	carcinoma	Substitution - Missense
c.1563G>T; p.K521N; 5:53062890-53062890	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2913C>T; p.F971F; 5:53078859-53078859	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2913C>T; p.F971F; 5:53078859-53078859	skin	malignant_melanoma	Substitution - coding silent
c.2913C>T; p.F971F; 5:53078859-53078859	skin	malignant_melanoma	Substitution - coding silent
c.527T>C; p.V176A; 5:53048667-53048667	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2205G>C; p.Q735H; 5:53070230-53070230	breast	carcinoma	Substitution - Missense
c.3162C>A; p.S1054S; 5:53083357-53083357	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.295+1G>T; p.?; 5:53042222-53042222	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.3252C>A; p.F1084L; 5:53083447-53083447	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.806_807insT; p.G270fs*14; 5:53055564-53055565	lung	carcinoma; adenocarcinoma	Insertion - Frameshift
c.2554delG; p.A852fs*12; 5:53073242-53073242	thyroid	carcinoma; anaplastic_carcinoma	Deletion - Frameshift
c.2571+1G>T; p.?; 5:53073260-53073260	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.2826A>C; p.R942S; 5:53078772-53078772	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2571+1G>T; p.?; 5:53073260-53073260	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.1123C>T; p.Q375*; 5:53058051-53058051	skin	malignant_melanoma	Substitution - Nonsense
c.524T>C; p.V175A; 5:53048664-53048664	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2632G>A; p.V878I; 5:53074445-53074445	pancreas	carcinoma	Substitution - Missense
c.207G>T; p.W69C; 5:53042133-53042133	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2269C>T; p.R757C; 5:53071971-53071971	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1353C>T; p.H451H; 5:53060941-53060941	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2609C>T; p.S870F; 5:53074422-53074422	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2864G>A; p.G955E; 5:53078810-53078810	skin	malignant_melanoma	Substitution - Missense
c.3139G>T; p.E1047*; 5:53081691-53081691	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3139G>T; p.E1047*; 5:53081691-53081691	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1353C>A; p.H451Q; 5:53060941-53060941	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1952G>C; p.S651T; 5:53067126-53067126	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2031C>T; p.L677L; 5:53067205-53067205	breast	carcinoma	Substitution - coding silent
c.3402T>C; p.V1134V; 5:53089999-53089999	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3143T>A; p.L1048*; 5:53081695-53081695	liver	carcinoma; hepatocellular_carcinoma	Substitution - Nonsense
c.2516C>A; p.T839N; 5:53073204-53073204	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1895C>T; p.S632F; 5:53065929-53065929	skin	malignant_melanoma	Substitution - Missense
c.1130A>G; p.E377G; 5:53058058-53058058	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.548A>G; p.N183S; 5:53048688-53048688	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1372C>T; p.R458W; 5:53060960-53060960	breast	carcinoma	Substitution - Missense
c.2077C>T; p.Q693*; 5:53067251-53067251	ovary	carcinoma; serous_carcinoma	Substitution - Nonsense
c.2201C>T; p.A734V; 5:53070226-53070226	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3284C>T; p.T1095M; 5:53086977-53086977	breast	carcinoma	Substitution - Missense
c.2213C>T; p.P738L; 5:53070238-53070238	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1991_1992insA; p.I666fs*24; 5:53067165-53067166	stomach	carcinoma; intestinal_adenocarcinoma	Insertion - Frameshift
c.815G>A; p.R272Q; 5:53055573-53055573	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.815G>A; p.R272Q; 5:53055573-53055573	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3166A>T; p.S1056C; 5:53083361-53083361	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.815G>A; p.R272Q; 5:53055573-53055573	skin	malignant_melanoma	Substitution - Missense
c.1430C>T; p.T477M; 5:53061018-53061018	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2741G>A; p.S914N; 5:53075137-53075137	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3542G>T; p.S1181I; 5:53090595-53090595	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.263C>T; p.S88F; 5:53042189-53042189	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.262T>C; p.S88P; 5:53042188-53042188	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.630+1G>T; p.?; 5:53048771-53048771	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.2297G>A; p.G766D; 5:53071999-53071999	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1675G>A; p.A559T; 5:53064984-53064984	stomach	adenocarcinoma	Substitution - Missense
c.2328G>T; p.E776D; 5:53072030-53072030	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2013G>T; p.K671N; 5:53067187-53067187	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.539A>G; p.D180G; 5:53048679-53048679	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2780A>G; p.N927S; 5:53075259-53075259	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2537C>T; p.S846L; 5:53073225-53073225	skin	malignant_melanoma	Substitution - Missense
c.2241C>A; p.P747P; 5:53071943-53071943	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3537C>A; p.L1179L; 5:53090590-53090590	skin	malignant_melanoma	Substitution - coding silent
c.3225G>C; p.V1075V; 5:53083420-53083420	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.3225G>C; p.V1075V; 5:53083420-53083420	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.3469G>A; p.G1157S; 5:53090522-53090522	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3349-1G>A; p.?; 5:53089945-53089945	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.3469G>A; p.G1157S; 5:53090522-53090522	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3469G>A; p.G1157S; 5:53090522-53090522	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2117G>C; p.G706A; 5:53070142-53070142	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3104T>A; p.V1035E; 5:53081656-53081656	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2635G>A; p.G879S; 5:53074448-53074448	skin	malignant_melanoma	Substitution - Missense
c.2548delT; p.F851fs*13; 5:53073236-53073236	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1086C>T; p.F362F; 5:53056139-53056139	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1658G>A; p.R553Q; 5:53064967-53064967	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2876C>T; p.S959L; 5:53078822-53078822	skin	malignant_melanoma	Substitution - Missense
c.1658G>A; p.R553Q; 5:53064967-53064967	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1049T>A; p.L350Q; 5:53056102-53056102	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1020_1021insT; p.N343fs*4; 5:53056073-53056074	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.264C>A; p.S88S; 5:53042190-53042190	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1447C>T; p.R483*; 5:53061035-53061035	stomach	adenocarcinoma	Substitution - Nonsense
c.1447C>T; p.R483*; 5:53061035-53061035	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2815C>T; p.H939Y; 5:53075294-53075294	skin	malignant_melanoma	Substitution - Missense
c.327G>A; p.M109I; 5:53045032-53045032	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1974A>C; p.E658D; 5:53067148-53067148	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2742-1G>T; p.?; 5:53075220-53075220	lung; right_upper_lobe	carcinoma; adenocarcinoma	Unknown
c.490C>A; p.P164T; 5:53048465-53048465	central_nervous_system; brain	glioma	Substitution - Missense
c.2214C>G; p.P738P; 5:53070239-53070239	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.1790G>A; p.R597H; 5:53065099-53065099	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1790G>A; p.R597H; 5:53065099-53065099	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1790G>A; p.R597H; 5:53065099-53065099	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2763G>T; p.K921N; 5:53075242-53075242	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.630+2T>G; p.?; 5:53048772-53048772	pancreas	carcinoma	Unknown
c.630+2T>G; p.?; 5:53048772-53048772	pancreas	carcinoma; ductal_carcinoma	Unknown
c.11A>G; p.E4G; 5:52989479-52989479	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.370G>A; p.G124R; 5:53045075-53045075	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.940T>C; p.Y314H; 5:53055993-53055993	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3307T>C; p.Y1103H; 5:53087000-53087000	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3157G>A; p.A1053T; 5:53083352-53083352	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.251C>T; p.P84L; 5:53042177-53042177	skin; ear	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2566C>T; p.L856L; 5:53073254-53073254	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2236-1G>T; p.?; 5:53071937-53071937	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.323A>T; p.E108V; 5:53045028-53045028	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1451G>A; p.G484D; 5:53061039-53061039	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2011A>G; p.K671E; 5:53067185-53067185	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.388-8C>G; p.?; 5:53048355-53048355	eye; uveal_tract	malignant_melanoma; mixed	Unknown
c.2011A>G; p.K671E; 5:53067185-53067185	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2999A>G; p.K1000R; 5:53080581-53080581	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense

The somatic mutations from COSMIC database