Entrez Gene

Basic Information
Gene ID	3491
Name	CYR61

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.861C>G; p.S287R; 1:85582757-85582757	kidney	other; neoplasm	Substitution - Missense
c.42C>T; p.T14T; 1:85581026-85581026	skin	malignant_melanoma	Substitution - coding silent
c.679C>T; p.Q227*; 1:85582460-85582460	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.653G>A; p.R218H; 1:85582434-85582434	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.706T>C; p.W236R; 1:85582487-85582487	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.643A>T; p.M215L; 1:85582424-85582424	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.189C>G; p.D63E; 1:85581490-85581490	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.409G>T; p.E137*; 1:85582059-85582059	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.409G>T; p.E137*; 1:85582059-85582059	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1012G>A; p.E338K; 1:85582908-85582908	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.107C>A; p.A36E; 1:85581408-85581408	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.107C>A; p.A36E; 1:85581408-85581408	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.107C>A; p.A36E; 1:85581408-85581408	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1012G>A; p.E338K; 1:85582908-85582908	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.107C>A; p.A36E; 1:85581408-85581408	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.107C>A; p.A36E; 1:85581408-85581408	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1012G>A; p.E338K; 1:85582908-85582908	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.107C>A; p.A36E; 1:85581408-85581408	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.490G>A; p.D164N; 1:85582140-85582140	breast	carcinoma	Substitution - Missense
c.150C>T; p.C50C; 1:85581451-85581451	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.351T>C; p.C117C; 1:85582001-85582001	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.79C>T; p.P27S; 1:85581380-85581380	pancreas	carcinoma	Substitution - Missense
c.403C>T; p.P135S; 1:85582053-85582053	skin	malignant_melanoma	Substitution - Missense
c.556G>A; p.D186N; 1:85582206-85582206	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.646G>A; p.E216K; 1:85582427-85582427	skin	malignant_melanoma	Substitution - Missense
c.579G>A; p.T193T; 1:85582229-85582229	skin	malignant_melanoma	Substitution - coding silent
c.848G>A; p.G283D; 1:85582744-85582744	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.685T>C; p.C229R; 1:85582466-85582466	breast	carcinoma	Substitution - Missense
c.1102C>T; p.P368S; 1:85582998-85582998	skin	malignant_melanoma	Substitution - Missense
c.378C>T; p.G126G; 1:85582028-85582028	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.888C>G; p.V296V; 1:85582784-85582784	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.618A>C; p.S206S; 1:85582268-85582268	liver	carcinoma	Substitution - coding silent
c.453C>G; p.V151V; 1:85582103-85582103	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.618A>C; p.S206S; 1:85582268-85582268	liver	carcinoma	Substitution - coding silent
c.618A>C; p.S206S; 1:85582268-85582268	liver	carcinoma	Substitution - coding silent
c.438C>G; p.P146P; 1:85582088-85582088	ovary	other; neoplasm	Substitution - coding silent
c.853A>C; p.K285Q; 1:85582749-85582749	central_nervous_system; medulla	primitive_neuroectodermal_tumour-medulloblastoma; classic	Substitution - Missense
c.131G>T; p.G44V; 1:85581432-85581432	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.131G>T; p.G44V; 1:85581432-85581432	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.131G>T; p.G44V; 1:85581432-85581432	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.131G>T; p.G44V; 1:85581432-85581432	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.131G>T; p.G44V; 1:85581432-85581432	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.765C>T; p.N255N; 1:85582546-85582546	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.530G>A; p.G177D; 1:85582180-85582180	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1046T>C; p.M349T; 1:85582942-85582942	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1046T>C; p.M349T; 1:85582942-85582942	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.367T>C; p.C123R; 1:85582017-85582017	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.743C>T; p.S248F; 1:85582524-85582524	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.290G>A; p.G97D; 1:85581940-85581940	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.290G>A; p.G97D; 1:85581940-85581940	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1142A>G; p.D381G; 1:85583038-85583038	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.892T>C; p.F298L; 1:85582788-85582788	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1080G>A; p.P360P; 1:85582976-85582976	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1138A>T; p.R380W; 1:85583034-85583034	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.769G>C; p.E257Q; 1:85582550-85582550	breast	carcinoma	Substitution - Missense
c.15C>T; p.I5I; 1:85580999-85580999	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.717C>T; p.C239C; 1:85582498-85582498	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1010G>A; p.C337Y; 1:85582906-85582906	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1011C>T; p.C337C; 1:85582907-85582907	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent

The somatic mutations from COSMIC database