Entrez Gene

Basic Information
Gene ID	29775
Name	CARD10

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.743G>C; p.C248S; 22:37510378-37510378	breast	carcinoma	Substitution - Missense
c.2806G>A; p.E936K; 22:37491813-37491813	prostate	carcinoma	Substitution - Missense
c.1128G>A; p.L376L; 22:37507892-37507892	pancreas	carcinoma	Substitution - coding silent
c.1205G>A; p.R402H; 22:37506370-37506370	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2841T>C; p.T947T; 22:37491778-37491778	parathyroid	carcinoma	Substitution - coding silent
c.865C>T; p.R289W; 22:37510256-37510256	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.747A>T; p.A249A; 22:37510374-37510374	breast	carcinoma	Substitution - coding silent
c.1677T>A; p.L559L; 22:37502712-37502712	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.1677T>A; p.L559L; 22:37502712-37502712	liver	carcinoma	Substitution - coding silent
c.1945G>A; p.E649K; 22:37497021-37497021	skin	malignant_melanoma	Substitution - Missense
c.566G>A; p.R189Q; 22:37516106-37516106	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1161_1162insA; p.L388fs*5; 22:37507858-37507859	pancreas	carcinoma; ductal_carcinoma	Insertion - Frameshift
c.2512C>T; p.R838W; 22:37492767-37492767	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.1598G>T; p.R533L; 22:37504222-37504222	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2512C>T; p.R838W; 22:37492767-37492767	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2206G>A; p.D736N; 22:37495857-37495857	skin	malignant_melanoma	Substitution - Missense
c.415G>A; p.E139K; 22:37516257-37516257	skin	malignant_melanoma	Substitution - Missense
c.426G>A; p.R142R; 22:37516246-37516246	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1493T>C; p.M498T; 22:37504660-37504660	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2158G>C; p.D720H; 22:37495905-37495905	soft_tissue; fibrous_tissue_and_uncertain_o	dermatofibrosarcoma_protuberans	Substitution - Missense
c.1471G>A; p.A491T; 22:37504682-37504682	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.314C>A; p.P105H; 22:37518030-37518030	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2038C>T; p.P680S; 22:37496470-37496470	breast	carcinoma	Substitution - Missense
c.913G>A; p.A305T; 22:37508679-37508679	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2310G>A; p.Q770Q; 22:37495580-37495580	liver	carcinoma	Substitution - coding silent
c.148_149insT; p.Y50fs*45; 22:37519052-37519053	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1992C>A; p.A664A; 22:37496516-37496516	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - coding silent
c.1511A>G; p.H504R; 22:37504642-37504642	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.550C>T; p.R184C; 22:37516122-37516122	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2880G>A; p.R960R; 22:37491378-37491378	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2880G>A; p.R960R; 22:37491378-37491378	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.439C>T; p.R147C; 22:37516233-37516233	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.109C>T; p.R37W; 22:37519092-37519092	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1255T>C; p.Y419H; 22:37506320-37506320	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1035G>A; p.E345E; 22:37508557-37508557	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2054C>T; p.S685L; 22:37496454-37496454	skin	malignant_melanoma	Substitution - Missense
c.2536C>T; p.R846W; 22:37492743-37492743	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2230G>A; p.E744K; 22:37495833-37495833	NS	malignant_melanoma	Substitution - Missense
c.2805C>G; p.N935K; 22:37491814-37491814	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2536C>T; p.R846W; 22:37492743-37492743	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2536C>T; p.R846W; 22:37492743-37492743	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1818C>T; p.S606S; 22:37497148-37497148	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.160T>G; p.C54G; 22:37519041-37519041	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1927G>A; p.A643T; 22:37497039-37497039	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.422G>A; p.R141Q; 22:37516250-37516250	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.1694G>A; p.G565D; 22:37502695-37502695	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1551T>C; p.N517N; 22:37504269-37504269	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - coding silent
c.2060-1G>A; p.?; 22:37496004-37496004	skin	malignant_melanoma	Unknown
c.3030_3031GG>AT; p.E1011*; 22:37491227-37491228	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2619C>A; p.F873L; 22:37492660-37492660	ovary	other; neoplasm	Substitution - Missense
c.1834G>T; p.E612*; 22:37497132-37497132	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1969C>T; p.L657L; 22:37496539-37496539	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1372A>C; p.T458P; 22:37506203-37506203	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.372C>A; p.L124L; 22:37517972-37517972	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.372C>A; p.L124L; 22:37517972-37517972	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.2517G>A; p.P839P; 22:37492762-37492762	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.1203C>A; p.S401R; 22:37506372-37506372	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2517G>A; p.P839P; 22:37492762-37492762	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2190G>C; p.E730D; 22:37495873-37495873	soft_tissue; fibrous_tissue_and_uncertain_o	dermatofibrosarcoma_protuberans	Substitution - Missense
c.3064A>G; p.S1022G; 22:37491194-37491194	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1995G>A; p.E665E; 22:37496513-37496513	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1107G>A; p.T369T; 22:37507913-37507913	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1313C>T; p.T438I; 22:37506262-37506262	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.2182G>A; p.A728T; 22:37495881-37495881	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.2059G>A; p.A687T; 22:37496449-37496449	skin	malignant_melanoma	Substitution - Missense
c.759G>A; p.R253R; 22:37510362-37510362	skin	malignant_melanoma	Substitution - coding silent
c.1435C>A; p.L479M; 22:37504718-37504718	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2606C>T; p.S869F; 22:37492673-37492673	thyroid	carcinoma	Substitution - Missense
c.1866G>A; p.S622S; 22:37497100-37497100	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1934T>C; p.M645T; 22:37497032-37497032	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.476_477CC>TT; p.A159V; 22:37516195-37516196	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.814_819delAAGGAG; p.K272_E273delKE; 22:37510302-37510307	endometrium	carcinoma; endometrioid_carcinoma	Deletion - In frame
c.814_819delAAGGAG; p.K272_E273delKE; 22:37510302-37510307	endometrium	carcinoma; endometrioid_carcinoma	Deletion - In frame
c.814_819delAAGGAG; p.K272_E273delKE; 22:37510302-37510307	endometrium	carcinoma; endometrioid_carcinoma	Deletion - In frame
c.995_996insCAG; p.S331_R332insS; 22:37508596-37508597	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - In frame
c.814_819delAAGGAG; p.K272_E273delKE; 22:37510302-37510307	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - In frame
c.814_819delAAGGAG; p.K272_E273delKE; 22:37510302-37510307	ovary	carcinoma; serous_carcinoma	Deletion - In frame
c.2754G>T; p.K918N; 22:37491865-37491865	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2754G>T; p.K918N; 22:37491865-37491865	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2059+1G>A; p.?; 22:37496448-37496448	skin	malignant_melanoma	Unknown
c.1759C>G; p.R587G; 22:37502630-37502630	prostate	carcinoma	Substitution - Missense
c.2724C>T; p.I908I; 22:37492462-37492462	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1759C>T; p.R587W; 22:37502630-37502630	skin	malignant_melanoma	Substitution - Missense
c.2879G>A; p.R960Q; 22:37491379-37491379	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1759C>T; p.R587W; 22:37502630-37502630	urinary_tract; bladder	carcinoma	Substitution - Missense
c.824A>G; p.D275G; 22:37510297-37510297	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2287G>A; p.V763M; 22:37495776-37495776	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2287G>A; p.V763M; 22:37495776-37495776	pancreas	carcinoma	Substitution - Missense
c.544C>T; p.Q182*; 22:37516128-37516128	breast	carcinoma	Substitution - Nonsense
c.2422G>A; p.V808M; 22:37494140-37494140	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.851G>A; p.R284H; 22:37510270-37510270	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1698C>G; p.L566L; 22:37502691-37502691	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1168G>A; p.E390K; 22:37507852-37507852	skin	malignant_melanoma	Substitution - Missense
c.1168G>A; p.E390K; 22:37507852-37507852	skin	malignant_melanoma	Substitution - Missense
c.2108G>T; p.G703V; 22:37495955-37495955	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1621G>A; p.A541T; 22:37504199-37504199	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1990G>A; p.A664T; 22:37496518-37496518	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.316G>A; p.E106K; 22:37518028-37518028	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2245C>T; p.R749W; 22:37495818-37495818	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2577C>T; p.L859L; 22:37492702-37492702	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2245C>T; p.R749W; 22:37495818-37495818	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2245C>T; p.R749W; 22:37495818-37495818	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2175C>T; p.C725C; 22:37495888-37495888	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.819_820insAAGGAG; p.E273_P274insKE; 22:37510301-37510302	endometrium	carcinoma; endometrioid_carcinoma	Insertion - In frame
c.2542G>A; p.V848M; 22:37492737-37492737	bone; femur	chondrosarcoma	Substitution - Missense
c.1578delC; p.S527fs*31; 22:37504242-37504242	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2197C>T; p.R733*; 22:37495866-37495866	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1578delC; p.S527fs*31; 22:37504242-37504242	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.527G>A; p.R176Q; 22:37516145-37516145	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1512C>G; p.H504Q; 22:37504641-37504641	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2850T>C; p.N950N; 22:37491769-37491769	skin	malignant_melanoma	Substitution - coding silent
c.256C>G; p.R86G; 22:37518088-37518088	skin	malignant_melanoma	Substitution - Missense
c.2850T>C; p.N950N; 22:37491769-37491769	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2485C>T; p.R829W; 22:37492794-37492794	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2595C>A; p.D865E; 22:37492684-37492684	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1140C>T; p.R380R; 22:37507880-37507880	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2653G>T; p.E885*; 22:37492533-37492533	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1552C>T; p.R518W; 22:37504268-37504268	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2246G>T; p.R749L; 22:37495817-37495817	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1380C>G; p.L460L; 22:37506195-37506195	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1446C>T; p.F482F; 22:37504707-37504707	skin	malignant_melanoma	Substitution - coding silent
c.2687A>G; p.K896R; 22:37492499-37492499	liver	carcinoma	Substitution - Missense
c.2687A>G; p.K896R; 22:37492499-37492499	liver	carcinoma	Substitution - Missense
c.324C>G; p.F108L; 22:37518020-37518020	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.239G>A; p.R80H; 22:37518105-37518105	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2497C>A; p.P833T; 22:37492782-37492782	liver	carcinoma	Substitution - Missense
c.1761G>C; p.R587R; 22:37502628-37502628	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.559C>T; p.R187W; 22:37516113-37516113	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2188G>A; p.E730K; 22:37495875-37495875	skin	malignant_melanoma	Substitution - Missense
c.804G>A; p.K268K; 22:37510317-37510317	skin	malignant_melanoma	Substitution - coding silent
c.1087C>T; p.L363L; 22:37507933-37507933	skin	malignant_melanoma	Substitution - coding silent
c.1211G>A; p.R404Q; 22:37506364-37506364	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.601C>T; p.R201W; 22:37516071-37516071	ovary	other; neoplasm	Substitution - Missense
c.1189C>G; p.Q397E; 22:37507831-37507831	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.288C>T; p.F96F; 22:37518056-37518056	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.2677G>A; p.G893R; 22:37492509-37492509	skin	malignant_melanoma	Substitution - Missense
c.866G>A; p.R289Q; 22:37510255-37510255	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.866G>A; p.R289Q; 22:37510255-37510255	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.866G>A; p.R289Q; 22:37510255-37510255	thyroid	other; neoplasm	Substitution - Missense
c.866G>A; p.R289Q; 22:37510255-37510255	thyroid	other; neoplasm	Substitution - Missense
c.2222G>A; p.R741Q; 22:37495841-37495841	liver	carcinoma	Substitution - Missense
c.1787+2T>C; p.?; 22:37502600-37502600	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.423A>G; p.R141R; 22:37516249-37516249	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2222G>A; p.R741Q; 22:37495841-37495841	liver	carcinoma	Substitution - Missense
c.2254C>T; p.P752S; 22:37495809-37495809	skin	malignant_melanoma	Substitution - Missense
c.2743G>T; p.V915F; 22:37492443-37492443	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.466C>T; p.Q156*; 22:37516206-37516206	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense

The somatic mutations from COSMIC database