Entrez Gene

Basic Information
Gene ID	246778
Name	IL27

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.655C>T; p.R219W; 16:28499728-28499728	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.66T>C; p.V22V; 16:28504016-28504016	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.576G>A; p.P192P; 16:28499807-28499807	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.259C>A; p.L87I; 16:28503739-28503739	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.94C>A; p.P32T; 16:28503988-28503988	breast	carcinoma	Substitution - Missense
c.355C>T; p.L119L; 16:28502083-28502083	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.192G>C; p.Q64H; 16:28503890-28503890	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.298C>T; p.L100F; 16:28503700-28503700	liver	carcinoma	Substitution - Missense
c.298C>T; p.L100F; 16:28503700-28503700	liver	carcinoma	Substitution - Missense
c.12G>T; p.T4T; 16:28506800-28506800	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.652G>C; p.V218L; 16:28499731-28499731	breast	carcinoma	Substitution - Missense
c.650C>T; p.A217V; 16:28499733-28499733	skin	malignant_melanoma	Substitution - Missense
c.336G>A; p.T112T; 16:28502102-28502102	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.231C>T; p.N77N; 16:28503767-28503767	oesophagus	carcinoma	Substitution - coding silent
c.353C>T; p.A118V; 16:28502085-28502085	pancreas	carcinoma	Substitution - Missense
c.226G>A; p.V76M; 16:28503772-28503772	skin	malignant_melanoma	Substitution - Missense
c.207G>A; p.A69A; 16:28503791-28503791	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.207G>A; p.A69A; 16:28503791-28503791	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.207G>A; p.A69A; 16:28503791-28503791	skin	malignant_melanoma	Substitution - coding silent
c.81G>A; p.W27*; 16:28504001-28504001	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.655C>A; p.R219R; 16:28499728-28499728	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.415delG; p.A139fs*2; 16:28502023-28502023	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.504_506delGGA; p.E176delE; 16:28499877-28499879	endometrium	carcinoma; endometrioid_carcinoma	Deletion - In frame
c.504_506delGGA; p.E176delE; 16:28499877-28499879	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - In frame
c.276G>T; p.L92L; 16:28503722-28503722	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.316C>T; p.L106F; 16:28502122-28502122	skin	malignant_melanoma	Substitution - Missense
c.561C>T; p.S187S; 16:28499822-28499822	ovary	other; neoplasm	Substitution - coding silent
c.309G>A; p.P103P; 16:28502129-28502129	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.386G>A; p.W129*; 16:28502052-28502052	oesophagus	carcinoma; adenocarcinoma	Substitution - Nonsense
c.200G>A; p.R67H; 16:28503882-28503882	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.436G>A; p.D146N; 16:28502002-28502002	skin	malignant_melanoma	Substitution - Missense
c.573_574CC>AA; p.P192T; 16:28499809-28499810	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.436G>A; p.D146N; 16:28502002-28502002	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.110A>T; p.Q37L; 16:28503972-28503972	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.196C>A; p.H66N; 16:28503886-28503886	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.651C>T; p.A217A; 16:28499732-28499732	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.657G>A; p.R219R; 16:28499726-28499726	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.259C>T; p.L87F; 16:28503739-28503739	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.402G>A; p.R134R; 16:28502036-28502036	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.259C>T; p.L87F; 16:28503739-28503739	urinary_tract; bladder	carcinoma	Substitution - Missense
c.335C>T; p.T112M; 16:28502103-28502103	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.510G>A; p.E170E; 16:28499873-28499873	breast	carcinoma	Substitution - coding silent
c.498G>C; p.E166D; 16:28499885-28499885	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.498G>C; p.E166D; 16:28499885-28499885	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.498G>C; p.E166D; 16:28499885-28499885	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.575C>T; p.P192L; 16:28499808-28499808	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.723C>T; p.P241P; 16:28499660-28499660	central_nervous_system; brain	glioma	Substitution - coding silent
c.356T>C; p.L119P; 16:28502082-28502082	thyroid	other; neoplasm	Substitution - Missense
c.356T>C; p.L119P; 16:28502082-28502082	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.356T>C; p.L119P; 16:28502082-28502082	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.637G>A; p.V213I; 16:28499746-28499746	bone; pelvis	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.177C>T; p.S59S; 16:28503905-28503905	skin	malignant_melanoma	Substitution - coding silent
c.177C>T; p.S59S; 16:28503905-28503905	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.630G>T; p.L210F; 16:28499753-28499753	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.689C>G; p.S230*; 16:28499694-28499694	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.31+1G>A; p.?; 16:28506780-28506780	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.139T>C; p.F47L; 16:28503943-28503943	prostate	carcinoma	Substitution - Missense
c.434G>A; p.R145H; 16:28502004-28502004	lung	carcinoma; adenocarcinoma	Substitution - Missense

The somatic mutations from COSMIC database