Entrez Gene

Basic Information
Gene ID	23365
Name	ARHGEF12

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.2027C>T; p.S676F; 11:120451695-120451695	NS	malignant_melanoma	Substitution - Missense
c.2583C>T; p.I861I; 11:120460727-120460727	skin	malignant_melanoma	Substitution - coding silent
c.4440G>A; p.W1480*; 11:120481462-120481462	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.4104G>A; p.M1368I; 11:120480297-120480297	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.4104G>A; p.M1368I; 11:120480297-120480297	pancreas	carcinoma	Substitution - Missense
c.1204-1G>T; p.?; 11:120442103-120442103	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.1178T>C; p.V393A; 11:120441792-120441792	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3896A>G; p.N1299S; 11:120480089-120480089	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1390T>C; p.Y464H; 11:120446447-120446447	breast	carcinoma	Substitution - Missense
c.3070G>A; p.G1024R; 11:120474596-120474596	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.177G>A; p.E59E; 11:120409428-120409428	endometrium	carcinoma; serous_carcinoma	Substitution - coding silent
c.4396G>T; p.A1466S; 11:120481418-120481418	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1165T>C; p.L389L; 11:120441779-120441779	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.338G>A; p.R113Q; 11:120421842-120421842	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.338G>A; p.R113Q; 11:120421842-120421842	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1724T>A; p.L575H; 11:120448335-120448335	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.338G>A; p.R113Q; 11:120421842-120421842	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4148A>T; p.D1383V; 11:120480341-120480341	breast	carcinoma	Substitution - Missense
c.3454G>A; p.G1152R; 11:120477448-120477448	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3454G>A; p.G1152R; 11:120477448-120477448	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.217G>A; p.V73I; 11:120420770-120420770	pancreas	carcinoma	Substitution - Missense
c.2973G>A; p.Q991Q; 11:120473067-120473067	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.142G>T; p.D48Y; 11:120407823-120407823	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3069A>G; p.E1023E; 11:120474595-120474595	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.361C>G; p.L121V; 11:120424370-120424370	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1924G>C; p.D642H; 11:120451592-120451592	thyroid	other; neoplasm	Substitution - Missense
c.2293G>T; p.D765Y; 11:120458147-120458147	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.33G>C; p.R11S; 11:120406118-120406118	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.280G>A; p.V94I; 11:120420833-120420833	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4028T>C; p.L1343P; 11:120480221-120480221	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.4335C>T; p.I1445I; 11:120481357-120481357	skin	malignant_melanoma	Substitution - coding silent
c.1873C>T; p.R625C; 11:120451541-120451541	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4335C>T; p.I1445I; 11:120481357-120481357	skin	malignant_melanoma	Substitution - coding silent
c.1669G>T; p.V557L; 11:120448280-120448280	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.4013G>A; p.R1338Q; 11:120480206-120480206	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2491_2492insT; p.S833fs*15; 11:120459284-120459285	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.488C>T; p.P163L; 11:120428150-120428150	skin	malignant_melanoma	Substitution - Missense
c.4273C>A; p.Q1425K; 11:120481295-120481295	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3566C>T; p.S1189L; 11:120478189-120478189	skin	malignant_melanoma	Substitution - Missense
c.2619C>T; p.S873S; 11:120465242-120465242	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2541A>G; p.E847E; 11:120460685-120460685	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1589+9T>C; p.?; 11:120447094-120447094	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.416A>G; p.Y139C; 11:120428078-120428078	liver	carcinoma	Substitution - Missense
c.3051A>C; p.K1017N; 11:120474577-120474577	skin	malignant_melanoma	Substitution - Missense
c.2719C>T; p.R907*; 11:120465342-120465342	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2234G>A; p.S745N; 11:120458088-120458088	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3708C>T; p.I1236I; 11:120478331-120478331	skin	malignant_melanoma	Substitution - coding silent
c.1968A>C; p.T656T; 11:120451636-120451636	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3453-8delC; p.?; 11:120477439-120477439	stomach	carcinoma; diffuse_adenocarcinoma	Unknown
c.127G>T; p.D43Y; 11:120407808-120407808	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4157A>G; p.E1386G; 11:120480350-120480350	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3804T>G; p.G1268G; 11:120479997-120479997	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4157A>G; p.E1386G; 11:120480350-120480350	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.924+9T>C; p.?; 11:120431920-120431920	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.3396A>T; p.A1132A; 11:120477249-120477249	breast	carcinoma	Substitution - coding silent
c.3033G>A; p.R1011R; 11:120473127-120473127	skin	malignant_melanoma	Substitution - coding silent
c.982G>A; p.E328K; 11:120437365-120437365	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.982G>A; p.E328K; 11:120437365-120437365	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1513C>T; p.R505*; 11:120447009-120447009	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1350G>T; p.K450N; 11:120446407-120446407	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3799C>T; p.L1267L; 11:120479992-120479992	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.590A>T; p.E197V; 11:120429444-120429444	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2518C>G; p.Q840E; 11:120459311-120459311	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.742C>A; p.Q248K; 11:120429790-120429790	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3097G>T; p.D1033Y; 11:120474623-120474623	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3990T>G; p.T1330T; 11:120480183-120480183	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1619A>G; p.K540R; 11:120447903-120447903	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4192G>A; p.G1398R; 11:120480385-120480385	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.3124C>G; p.L1042V; 11:120475354-120475354	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.202C>G; p.L68V; 11:120420755-120420755	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1960G>T; p.E654*; 11:120451628-120451628	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.3139C>G; p.L1047V; 11:120475369-120475369	breast	carcinoma	Substitution - Missense
c.1749G>T; p.K583N; 11:120449120-120449120	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1525C>T; p.R509*; 11:120447021-120447021	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Nonsense
c.4412delC; p.E1473fs*38; 11:120481434-120481434	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1555G>A; p.A519T; 11:120447051-120447051	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1243T>C; p.S415P; 11:120442143-120442143	skin	malignant_melanoma	Substitution - Missense
c.3941C>T; p.P1314L; 11:120480134-120480134	skin	malignant_melanoma	Substitution - Missense
c.3941C>T; p.P1314L; 11:120480134-120480134	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1826G>A; p.R609H; 11:120449197-120449197	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2517T>G; p.L839L; 11:120459310-120459310	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.57-5T>C; p.?; 11:120407733-120407733	liver	carcinoma	Unknown
c.847A>T; p.T283S; 11:120431834-120431834	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1683G>A; p.E561E; 11:120448294-120448294	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4233C>T; p.I1411I; 11:120480426-120480426	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - coding silent
c.950G>T; p.R317I; 11:120437333-120437333	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1249G>A; p.E417K; 11:120442149-120442149	skin	malignant_melanoma	Substitution - Missense
c.4328C>T; p.T1443I; 11:120481350-120481350	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2779A>T; p.K927*; 11:120467233-120467233	liver	carcinoma	Substitution - Nonsense
c.2624C>T; p.P875L; 11:120465247-120465247	skin; arm	malignant_melanoma	Substitution - Missense
c.109G>A; p.E37K; 11:120407790-120407790	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.921A>T; p.A307A; 11:120431908-120431908	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.466C>T; p.L156F; 11:120428128-120428128	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3820G>A; p.V1274I; 11:120480013-120480013	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.4396G>A; p.A1466T; 11:120481418-120481418	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2008G>C; p.A670P; 11:120451676-120451676	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.524C>G; p.S175C; 11:120428186-120428186	urinary_tract; bladder	carcinoma	Substitution - Missense
c.414C>G; p.S138S; 11:120428076-120428076	pancreas	carcinoma	Substitution - coding silent
c.414C>G; p.S138S; 11:120428076-120428076	pancreas	carcinoma	Substitution - coding silent
c.4405C>A; p.P1469T; 11:120481427-120481427	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4574C>G; p.T1525S; 11:120484457-120484457	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.1229A>G; p.Y410C; 11:120442129-120442129	liver	carcinoma	Substitution - Missense
c.1554T>C; p.C518C; 11:120447050-120447050	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1229A>G; p.Y410C; 11:120442129-120442129	liver	carcinoma	Substitution - Missense
c.2683C>T; p.L895L; 11:120465306-120465306	skin	malignant_melanoma	Substitution - coding silent
c.3378A>G; p.L1126L; 11:120477231-120477231	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.3010T>C; p.Y1004H; 11:120473104-120473104	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.146G>T; p.S49I; 11:120409397-120409397	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.4467G>C; p.E1489D; 11:120481489-120481489	breast	carcinoma	Substitution - Missense
c.1144C>T; p.P382S; 11:120441758-120441758	prostate	carcinoma	Substitution - Missense
c.1197G>A; p.A399A; 11:120441811-120441811	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1197G>A; p.A399A; 11:120441811-120441811	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3116A>C; p.Y1039S; 11:120475346-120475346	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.216C>T; p.C72C; 11:120420769-120420769	pancreas	carcinoma	Substitution - coding silent
c.1295G>T; p.R432L; 11:120442195-120442195	central_nervous_system; brain	glioma	Substitution - Missense
c.3122T>C; p.L1041S; 11:120475352-120475352	stomach	adenocarcinoma	Substitution - Missense
c.1252A>G; p.T418A; 11:120442152-120442152	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3976T>C; p.Y1326H; 11:120480169-120480169	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.717C>T; p.I239I; 11:120429765-120429765	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.2764C>A; p.R922S; 11:120467218-120467218	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3868G>A; p.G1290R; 11:120480061-120480061	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.2221C>A; p.R741R; 11:120457752-120457752	liver	carcinoma	Substitution - coding silent
c.2977C>T; p.R993C; 11:120473071-120473071	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.342C>T; p.I114I; 11:120421846-120421846	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2584G>A; p.D862N; 11:120460728-120460728	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1781G>A; p.R594Q; 11:120449152-120449152	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.489G>A; p.P163P; 11:120428151-120428151	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1781G>A; p.R594Q; 11:120449152-120449152	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1726C>A; p.P576T; 11:120448337-120448337	skin	malignant_melanoma	Substitution - Missense
c.4441G>T; p.G1481*; 11:120481463-120481463	breast	carcinoma	Substitution - Nonsense
c.2447G>A; p.R816Q; 11:120459240-120459240	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1659G>T; p.K553N; 11:120448270-120448270	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2173G>T; p.E725*; 11:120457234-120457234	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3363T>G; p.T1121T; 11:120476746-120476746	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4013G>T; p.R1338L; 11:120480206-120480206	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.471C>T; p.A157A; 11:120428133-120428133	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.714G>T; p.E238D; 11:120429762-120429762	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2978G>A; p.R993H; 11:120473072-120473072	large_intestine; colon	carcinoma	Substitution - Missense
c.3319G>A; p.A1107T; 11:120476702-120476702	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3319G>A; p.A1107T; 11:120476702-120476702	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1450C>T; p.R484W; 11:120446507-120446507	breast	carcinoma	Substitution - Missense
c.2699C>A; p.S900Y; 11:120465322-120465322	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.2699C>A; p.S900Y; 11:120465322-120465322	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3463G>A; p.D1155N; 11:120477457-120477457	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.685C>T; p.R229*; 11:120429733-120429733	breast	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.685C>T; p.R229*; 11:120429733-120429733	breast	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.4323C>A; p.P1441P; 11:120481345-120481345	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.77G>A; p.R26Q; 11:120407758-120407758	breast	carcinoma	Substitution - Missense
c.77G>A; p.R26Q; 11:120407758-120407758	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1093-1G>T; p.?; 11:120441706-120441706	lung	carcinoma; adenocarcinoma	Unknown
c.77G>A; p.R26Q; 11:120407758-120407758	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3799C>G; p.L1267V; 11:120479992-120479992	breast	carcinoma	Substitution - Missense
c.4153C>T; p.R1385C; 11:120480346-120480346	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.180G>T; p.E60D; 11:120409431-120409431	liver	carcinoma	Substitution - Missense
c.3573A>C; p.K1191N; 11:120478196-120478196	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2003C>T; p.S668F; 11:120451671-120451671	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3926G>T; p.G1309V; 11:120480119-120480119	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.3926G>T; p.G1309V; 11:120480119-120480119	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4354C>G; p.H1452D; 11:120481376-120481376	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.946G>T; p.E316*; 11:120437329-120437329	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.22A>G; p.I8V; 11:120337265-120337265	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1547G>A; p.R516Q; 11:120447043-120447043	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.545C>G; p.S182C; 11:120428207-120428207	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2399G>T; p.R800I; 11:120459192-120459192	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2295T>C; p.D765D; 11:120458149-120458149	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3509C>T; p.S1170L; 11:120477503-120477503	skin	malignant_melanoma	Substitution - Missense
c.25A>T; p.T9S; 11:120337268-120337268	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3567G>A; p.S1189S; 11:120478190-120478190	breast	carcinoma	Substitution - coding silent
c.3741G>A; p.R1247R; 11:120478364-120478364	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.676G>A; p.D226N; 11:120429724-120429724	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3940C>T; p.P1314S; 11:120480133-120480133	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3725C>T; p.P1242L; 11:120478348-120478348	skin	malignant_melanoma	Substitution - Missense
c.3333A>G; p.E1111E; 11:120476716-120476716	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.3085A>G; p.K1029E; 11:120474611-120474611	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2135A>T; p.D712V; 11:120457196-120457196	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4325T>C; p.M1442T; 11:120481347-120481347	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1906G>A; p.V636M; 11:120451574-120451574	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.457C>T; p.Q153*; 11:120428119-120428119	autonomic_ganglia	neuroblastoma	Substitution - Nonsense
c.4325T>C; p.M1442T; 11:120481347-120481347	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.413C>T; p.S138F; 11:120428075-120428075	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2623C>T; p.P875S; 11:120465246-120465246	skin; arm	malignant_melanoma	Substitution - Missense
c.2114G>A; p.R705H; 11:120457175-120457175	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2114G>A; p.R705H; 11:120457175-120457175	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2114G>A; p.R705H; 11:120457175-120457175	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2740G>C; p.D914H; 11:120467194-120467194	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3364G>A; p.V1122I; 11:120476747-120476747	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2712G>T; p.K904N; 11:120465335-120465335	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1365C>T; p.L455L; 11:120446422-120446422	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.664-9A>C; p.?; 11:120429703-120429703	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.3986G>A; p.R1329Q; 11:120480179-120480179	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2437T>C; p.F813L; 11:120459230-120459230	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2447G>T; p.R816L; 11:120459240-120459240	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1263C>G; p.I421M; 11:120442163-120442163	breast	carcinoma	Substitution - Missense
c.2597A>T; p.E866V; 11:120460741-120460741	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1162T>G; p.F388V; 11:120441776-120441776	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1162T>G; p.F388V; 11:120441776-120441776	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1688G>A; p.R563Q; 11:120448299-120448299	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1162T>G; p.F388V; 11:120441776-120441776	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1162T>G; p.F388V; 11:120441776-120441776	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.345C>G; p.I115M; 11:120421849-120421849	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3603G>A; p.G1201G; 11:120478226-120478226	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.378T>A; p.N126K; 11:120424387-120424387	pancreas	carcinoma	Substitution - Missense
c.1385G>A; p.R462H; 11:120446442-120446442	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2557C>T; p.R853*; 11:120460701-120460701	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1874G>A; p.R625H; 11:120451542-120451542	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2557C>T; p.R853*; 11:120460701-120460701	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1793C>T; p.P598L; 11:120449164-120449164	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3239_3243delTTAAG; p.K1081fs*12; 11:120475469-120475473	endometrium	carcinoma; endometrioid_carcinoma	Deletion - Frameshift
c.2602T>C; p.L868L; 11:120460746-120460746	pancreas	carcinoma	Substitution - coding silent
c.4389C>A; p.S1463S; 11:120481411-120481411	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.4212G>A; p.E1404E; 11:120480405-120480405	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3811G>A; p.E1271K; 11:120480004-120480004	ovary	other; neoplasm	Substitution - Missense
c.1303C>T; p.H435Y; 11:120445422-120445422	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.3317G>A; p.G1106D; 11:120476700-120476700	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3317G>A; p.G1106D; 11:120476700-120476700	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1303C>T; p.H435Y; 11:120445422-120445422	pancreas	carcinoma	Substitution - Missense
c.3719A>C; p.H1240P; 11:120478342-120478342	breast	carcinoma	Substitution - Missense
c.3226T>C; p.F1076L; 11:120475456-120475456	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.156G>T; p.K52N; 11:120409407-120409407	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3582T>C; p.S1194S; 11:120478205-120478205	skin	malignant_melanoma	Substitution - coding silent
c.1322C>T; p.P441L; 11:120445441-120445441	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3366C>T; p.V1122V; 11:120477219-120477219	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1898C>A; p.P633H; 11:120451566-120451566	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.819G>A; p.G273G; 11:120431806-120431806	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1737+7A>C; p.?; 11:120448355-120448355	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.1737+7A>C; p.?; 11:120448355-120448355	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.3740G>A; p.R1247Q; 11:120478363-120478363	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4095G>A; p.M1365I; 11:120480288-120480288	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2605C>T; p.L869L; 11:120460749-120460749	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.778G>T; p.A260S; 11:120429826-120429826	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4450G>A; p.E1484K; 11:120481472-120481472	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4450G>A; p.E1484K; 11:120481472-120481472	large_intestine; colon	carcinoma	Substitution - Missense
c.778G>T; p.A260S; 11:120429826-120429826	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.3547T>C; p.L1183L; 11:120478170-120478170	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2625A>T; p.P875P; 11:120465248-120465248	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.3211G>C; p.D1071H; 11:120475441-120475441	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.308C>T; p.A103V; 11:120421812-120421812	skin	malignant_melanoma	Substitution - Missense
c.1564A>T; p.I522F; 11:120447060-120447060	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.440G>A; p.R147H; 11:120428102-120428102	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.753G>A; p.E251E; 11:120429801-120429801	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.925-1G>C; p.?; 11:120437307-120437307	lung	carcinoma; adenocarcinoma	Unknown
c.1814G>A; p.R605Q; 11:120449185-120449185	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4584C>T; p.C1528C; 11:120484467-120484467	central_nervous_system; brain	glioma	Substitution - coding silent
c.512C>T; p.P171L; 11:120428174-120428174	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.512C>T; p.P171L; 11:120428174-120428174	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2733T>A; p.F911L; 11:120465356-120465356	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.4268C>T; p.P1423L; 11:120481290-120481290	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4021G>A; p.V1341M; 11:120480214-120480214	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1018G>A; p.G340R; 11:120440147-120440147	skin	malignant_melanoma	Substitution - Missense
c.1939C>T; p.R647C; 11:120451607-120451607	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.656G>A; p.R219Q; 11:120429510-120429510	skin	malignant_melanoma	Substitution - Missense
c.1444G>T; p.D482Y; 11:120446501-120446501	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2237T>C; p.V746A; 11:120458091-120458091	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.4624G>T; p.D1542Y; 11:120484507-120484507	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3550G>T; p.E1184*; 11:120478173-120478173	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense

The somatic mutations from COSMIC database