Entrez Gene

Basic Information
Gene ID	2319
Name	FLOT2

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.836A>C; p.D279A; 17:28881892-28881892	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.346G>T; p.G116W; 17:28883108-28883108	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.277G>T; p.G93C; 17:28883177-28883177	peritoneum; appendix	other; pseudomyxoma_peritonei	Substitution - Missense
c.818A>G; p.Q273R; 17:28881910-28881910	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.516T>C; p.T172T; 17:28882400-28882400	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.183G>T; p.T61T; 17:28884264-28884264	breast	carcinoma	Substitution - coding silent
c.577C>T; p.R193W; 17:28882339-28882339	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.999G>A; p.M333I; 17:28881291-28881291	prostate	carcinoma	Substitution - Missense
c.1171G>A; p.V391I; 17:28880790-28880790	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1244C>T; p.S415F; 17:28880717-28880717	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1244C>T; p.S415F; 17:28880717-28880717	urinary_tract; bladder	carcinoma	Substitution - Missense
c.151A>G; p.T51A; 17:28884296-28884296	breast	carcinoma	Substitution - Missense
c.75A>C; p.K25N; 17:28889001-28889001	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.306C>T; p.V102V; 17:28883148-28883148	skin	malignant_melanoma	Substitution - coding silent
c.417C>T; p.A139A; 17:28882621-28882621	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.223-4A>G; p.?; 17:28883235-28883235	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.121G>A; p.D41N; 17:28888955-28888955	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.615G>T; p.K205N; 17:28882202-28882202	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.955A>G; p.I319V; 17:28881335-28881335	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1097A>T; p.Q366L; 17:28881193-28881193	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.597G>A; p.K199K; 17:28882220-28882220	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.450C>T; p.L150L; 17:28882588-28882588	skin	malignant_melanoma	Substitution - coding silent
c.1009G>A; p.E337K; 17:28881281-28881281	breast	carcinoma	Substitution - Missense
c.957C>T; p.I319I; 17:28881333-28881333	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1047G>A; p.Q349Q; 17:28881243-28881243	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.903C>T; p.A301A; 17:28881825-28881825	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1018C>T; p.R340W; 17:28881272-28881272	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.567C>T; p.D189D; 17:28882349-28882349	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.833C>T; p.T278M; 17:28881895-28881895	central_nervous_system; brain	glioma	Substitution - Missense
c.1058A>G; p.D353G; 17:28881232-28881232	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.699+1G>T; p.?; 17:28882117-28882117	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.556G>A; p.A186T; 17:28882360-28882360	ovary	carcinoma	Substitution - Missense
c.55T>C; p.C19R; 17:28889021-28889021	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.547G>A; p.V183M; 17:28882369-28882369	liver	carcinoma	Substitution - Missense
c.547G>A; p.V183M; 17:28882369-28882369	liver	carcinoma	Substitution - Missense
c.700-1G>T; p.?; 17:28882029-28882029	thyroid	carcinoma	Unknown
c.380G>A; p.R127Q; 17:28882658-28882658	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1188C>T; p.N396N; 17:28880773-28880773	skin	malignant_melanoma	Substitution - coding silent
c.1119C>G; p.A373A; 17:28880842-28880842	breast	carcinoma	Substitution - coding silent
c.111G>A; p.W37*; 17:28888965-28888965	large_intestine; colon	carcinoma	Substitution - Nonsense
c.111G>A; p.W37*; 17:28888965-28888965	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.859C>T; p.R287C; 17:28881869-28881869	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.217G>A; p.A73T; 17:28884230-28884230	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.993G>T; p.E331D; 17:28881297-28881297	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.82G>A; p.V28M; 17:28888994-28888994	breast	carcinoma	Substitution - Missense
c.82G>A; p.V28M; 17:28888994-28888994	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1187A>C; p.N396T; 17:28880774-28880774	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.345C>T; p.L115L; 17:28883109-28883109	pancreas	carcinoma	Substitution - coding silent
c.739C>T; p.R247C; 17:28881989-28881989	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.739C>T; p.R247C; 17:28881989-28881989	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1204C>T; p.L402L; 17:28880757-28880757	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1251A>G; p.I417M; 17:28880597-28880597	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.519C>T; p.A173A; 17:28882397-28882397	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.237G>A; p.T79T; 17:28883217-28883217	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.990C>T; p.I330I; 17:28881300-28881300	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.75A>G; p.K25K; 17:28889001-28889001	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.918G>A; p.V306V; 17:28881372-28881372	thyroid	carcinoma	Substitution - coding silent
c.1223C>T; p.A408V; 17:28880738-28880738	central_nervous_system; brain	glioma	Substitution - Missense
c.183G>A; p.T61T; 17:28884264-28884264	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1057G>A; p.D353N; 17:28881233-28881233	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.722A>G; p.Y241C; 17:28882006-28882006	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.902C>T; p.A301V; 17:28881826-28881826	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.298A>C; p.K100Q; 17:28883156-28883156	urinary_tract; bladder	carcinoma	Substitution - Missense
c.298A>C; p.K100Q; 17:28883156-28883156	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.975G>A; p.A325A; 17:28881315-28881315	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.975G>A; p.A325A; 17:28881315-28881315	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.975G>A; p.A325A; 17:28881315-28881315	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.657C>T; p.F219F; 17:28882160-28882160	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1185G>T; p.V395V; 17:28880776-28880776	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - coding silent
c.162C>T; p.P54P; 17:28884285-28884285	skin	malignant_melanoma	Substitution - coding silent
c.162C>T; p.P54P; 17:28884285-28884285	skin	malignant_melanoma	Substitution - coding silent

The somatic mutations from COSMIC database