Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

2309

Name

FOXO3

The somatic mutations from COSMIC database

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.256G>C; p.G86R; 6:108561464-108561464

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1367C>A; p.P456Q; 6:108664200-108664200

 salivary_glandcarcinoma; adenoid_cystic_carcinomaSubstitution - Missense

c.1025_1026delCT; p.S344fs*27; 6:108663858-108663859

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.1141_1142insG; p.L382fs*3; 6:108663974-108663975

 stomachcarcinoma; diffuse_adenocarcinomaInsertion - Frameshift

c.1286C>A; p.S429Y; 6:108664119-108664119

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1525G>T; p.V509L; 6:108664358-108664358

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1173G>A; p.L391L; 6:108664006-108664006

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.672G>A; p.Q224Q; 6:108663505-108663505

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1968delG; p.N658fs*>16; 6:108664801-108664801

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1019A>G; p.D340G; 6:108663852-108663852

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.5C>T; p.A2V; 6:108561213-108561213

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.293C>T; p.A98V; 6:108561501-108561501

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.293C>T; p.A98V; 6:108561501-108561501

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.159C>G; p.A53A; 6:108561367-108561367

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.928C>T; p.R310C; 6:108663761-108663761

 skinmalignant_melanomaSubstitution - Missense

c.1376T>C; p.F459S; 6:108664209-108664209

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.202G>T; p.D68Y; 6:108561410-108561410

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1056C>G; p.A352A; 6:108663889-108663889

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1056C>G; p.A352A; 6:108663889-108663889

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - coding silent

c.1056C>G; p.A352A; 6:108663889-108663889

 pancreascarcinoid-endocrine_tumourSubstitution - coding silent

c.1056C>G; p.A352A; 6:108663889-108663889

 pancreascarcinoid-endocrine_tumourSubstitution - coding silent

c.1056C>G; p.A352A; 6:108663889-108663889

 upper_aerodigestive_tract; larynxcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1056C>G; p.A352A; 6:108663889-108663889

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.896G>T; p.S299I; 6:108663729-108663729

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1056C>G; p.A352A; 6:108663889-108663889

 thyroidother; neoplasmSubstitution - coding silent

c.1056C>G; p.A352A; 6:108663889-108663889

 pancreascarcinomaSubstitution - coding silent

c.1190C>T; p.P397L; 6:108664023-108664023

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1299G>C; p.T433T; 6:108664132-108664132

 stomachadenocarcinomaSubstitution - coding silent

c.718G>T; p.G240W; 6:108663551-108663551

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.1082C>T; p.P361L; 6:108663915-108663915

 bone; femurEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.882C>T; p.S294S; 6:108663715-108663715

 skinmalignant_melanomaSubstitution - coding silent

c.685G>T; p.G229C; 6:108663518-108663518

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1107G>C; p.L369L; 6:108663940-108663940

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.260C>T; p.T87M; 6:108561468-108561468

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1626C>T; p.G542G; 6:108664459-108664459

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1304T>C; p.F435S; 6:108664137-108664137

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.492C>T; p.D164D; 6:108561700-108561700

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.665G>A; p.R222Q; 6:108663498-108663498

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.1017T>C; p.D339D; 6:108663850-108663850

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.1017T>C; p.D339D; 6:108663850-108663850

 livercarcinoma; hepatocellular_carcinomaSubstitution - coding silent

c.1670T>G; p.M557R; 6:108664503-108664503

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.553G>A; p.E185K; 6:108561761-108561761

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - Missense

c.758C>T; p.S253F; 6:108663591-108663591

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1205C>T; p.S402L; 6:108664038-108664038

 skinmalignant_melanomaSubstitution - Missense

c.758C>T; p.S253F; 6:108663591-108663591

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1642C>T; p.R548C; 6:108664475-108664475

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1857C>T; p.S619S; 6:108664690-108664690

 thyroidother; neoplasmSubstitution - coding silent

c.33C>T; p.L11L; 6:108561241-108561241

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1022C>T; p.A341V; 6:108663855-108663855

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.924_928delCTTCC; p.D308fs*7; 6:108663757-108663761

 breastcarcinomaDeletion - Frameshift

c.1100C>T; p.P367L; 6:108663933-108663933

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.1263G>A; p.S421S; 6:108664096-108664096

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.419C>T; p.A140V; 6:108561627-108561627

 thyroidother; neoplasmSubstitution - Missense

c.1251C>A; p.T417T; 6:108664084-108664084

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.742C>T; p.R248W; 6:108663575-108663575

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.737delC; p.R248fs*111; 6:108663570-108663570

 skin; head_neckcarcinoma; squamous_cell_carcinomaDeletion - Frameshift

c.664C>T; p.R222W; 6:108663497-108663497

 prostatecarcinomaSubstitution - Missense

c.1744A>C; p.T582P; 6:108664577-108664577

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.159C>T; p.A53A; 6:108561367-108561367

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.159C>T; p.A53A; 6:108561367-108561367

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.749G>A; p.R250Q; 6:108663582-108663582

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.747G>A; p.R249R; 6:108663580-108663580

 livercarcinoma; hepatocellular_carcinomaSubstitution - coding silent

c.1165G>A; p.D389N; 6:108663998-108663998

 breastcarcinomaSubstitution - Missense

c.495G>T; p.L165L; 6:108561703-108561703

 thyroidother; neoplasmSubstitution - coding silent

c.968G>A; p.R323H; 6:108663801-108663801

 upper_aerodigestive_tract; pharynxcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1003G>A; p.E335K; 6:108663836-108663836

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.861G>A; p.Q287Q; 6:108663694-108663694

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1215G>A; p.G405G; 6:108664048-108664048

 breastcarcinomaSubstitution - coding silent

c.948C>T; p.N316N; 6:108663781-108663781

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1103G>A; p.R368Q; 6:108663936-108663936

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.647T>A; p.L216Q; 6:108663480-108663480

 skin; earmalignant_melanomaSubstitution - Missense

c.1085G>T; p.C362F; 6:108663918-108663918

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1356A>G; p.Q452Q; 6:108664189-108664189

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.1743A>G; p.Q581Q; 6:108664576-108664576

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.293C>G; p.A98G; 6:108561501-108561501

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1512_1513insC; p.S505fs*10; 6:108664345-108664346

 ovarycarcinoma; serous_carcinomaInsertion - Frameshift

c.1107G>T; p.L369L; 6:108663940-108663940

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1109C>A; p.T370N; 6:108663942-108663942

 pancreascarcinoma; acinar_carcinomaSubstitution - Missense

c.632G>A; p.R211Q; 6:108663465-108663465

 livercarcinomaSubstitution - Missense

c.1241T>A; p.F414Y; 6:108664074-108664074

 haematopoietic_and_lymphoid_tissue; central_nervous_systemlymphoid_neoplasm; primary_central_nervous_system_lymphomaSubstitution - Missense

c.632G>A; p.R211Q; 6:108663465-108663465

 livercarcinomaSubstitution - Missense

c.1233C>T; p.S411S; 6:108664066-108664066

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.952A>T; p.S318C; 6:108663785-108663785

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.790C>A; p.R264S; 6:108663623-108663623

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.803C>T; p.A268V; 6:108663636-108663636

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1230G>C; p.R410R; 6:108664063-108664063

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.159C>A; p.A53A; 6:108561367-108561367

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1274C>T; p.S425F; 6:108664107-108664107

 skinmalignant_melanomaSubstitution - Missense

c.1261delT; p.S421fs*20; 6:108664094-108664094

 kidneycarcinoma; clear_cell_renal_cell_carcinomaDeletion - Frameshift

c.1810C>A; p.H604N; 6:108664643-108664643

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1808G>A; p.G603D; 6:108664641-108664641

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1347G>T; p.Q449H; 6:108664180-108664180

 skinmalignant_melanomaSubstitution - Missense

c.1161G>T; p.M387I; 6:108663994-108663994

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1325C>T; p.S442F; 6:108664158-108664158

 skinmalignant_melanomaSubstitution - Missense

c.1325C>T; p.S442F; 6:108664158-108664158

 skinmalignant_melanomaSubstitution - Missense

c.1190C>G; p.P397R; 6:108664023-108664023

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.1190C>G; p.P397R; 6:108664023-108664023

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.613G>A; p.G205S; 6:108561821-108561821

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.16G>T; p.A6S; 6:108561224-108561224

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1206G>A; p.S402S; 6:108664039-108664039

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1305C>T; p.F435F; 6:108664138-108664138

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.1305C>T; p.F435F; 6:108664138-108664138

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1305C>T; p.F435F; 6:108664138-108664138

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1305C>T; p.F435F; 6:108664138-108664138

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1305C>T; p.F435F; 6:108664138-108664138

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1305C>T; p.F435F; 6:108664138-108664138

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1305C>T; p.F435F; 6:108664138-108664138

 livercarcinoma; hepatocellular_carcinomaSubstitution - coding silent

c.1305C>T; p.F435F; 6:108664138-108664138

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1305C>T; p.F435F; 6:108664138-108664138

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

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