Entrez Gene

Basic Information
Gene ID	23028
Name	KDM1A

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.34G>T; p.A12S; 1:23019630-23019630	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2516T>C; p.L839P; 1:23083249-23083249	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; primary_central_nervous_system_lymphoma	Substitution - Missense
c.1563A>G; p.L521L; 1:23072138-23072138	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2202A>C; p.E734D; 1:23081477-23081477	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.902T>G; p.V301G; 1:23055950-23055950	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2008T>C; p.W670R; 1:23079130-23079130	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1088C>A; p.A363D; 1:23059088-23059088	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1846C>T; p.Q616*; 1:23077339-23077339	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.928G>T; p.G310C; 1:23055976-23055976	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1207G>A; p.E403K; 1:23068566-23068566	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.1207G>A; p.E403K; 1:23068566-23068566	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma; medullomyoblastoma	Substitution - Missense
c.1207G>A; p.E403K; 1:23068566-23068566	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.2531G>A; p.R844Q; 1:23083264-23083264	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2346G>T; p.R782R; 1:23082267-23082267	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.2195C>T; p.A732V; 1:23081470-23081470	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1610C>T; p.A537V; 1:23072185-23072185	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.465C>T; p.P155P; 1:23030582-23030582	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.465C>T; p.P155P; 1:23030582-23030582	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.465C>T; p.P155P; 1:23030582-23030582	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.869T>C; p.I290T; 1:23055147-23055147	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.629C>T; p.S210F; 1:23050438-23050438	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.754G>C; p.E252Q; 1:23053803-23053803	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.515C>T; p.S172L; 1:23030632-23030632	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1176C>T; p.V392V; 1:23066068-23066068	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2135G>A; p.R712K; 1:23079632-23079632	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1843C>T; p.R615*; 1:23077336-23077336	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Nonsense
c.812G>A; p.R271Q; 1:23055090-23055090	breast	carcinoma	Substitution - Missense
c.926C>G; p.S309*; 1:23055974-23055974	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.959T>G; p.F320C; 1:23056007-23056007	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2427G>A; p.S809S; 1:23082348-23082348	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1045C>G; p.L349V; 1:23057538-23057538	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.2426C>G; p.S809W; 1:23082347-23082347	breast	carcinoma	Substitution - Missense
c.2513C>T; p.A838V; 1:23083246-23083246	skin; upper_leg	malignant_melanoma	Substitution - Missense
c.2584C>T; p.R862C; 1:23083317-23083317	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2317T>G; p.S773A; 1:23082238-23082238	prostate	carcinoma	Substitution - Missense
c.1936C>G; p.L646V; 1:23079058-23079058	skin	malignant_melanoma	Substitution - Missense
c.1321C>T; p.Q441*; 1:23068680-23068680	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Nonsense
c.2455C>T; p.R819*; 1:23083188-23083188	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2455C>T; p.R819*; 1:23083188-23083188	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.944G>A; p.R315Q; 1:23055992-23055992	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.378C>T; p.S126S; 1:23030495-23030495	skin	malignant_melanoma	Substitution - coding silent
c.21G>T; p.A7A; 1:23019617-23019617	liver	carcinoma	Substitution - coding silent
c.979T>A; p.L327M; 1:23056027-23056027	skin	malignant_melanoma	Substitution - Missense
c.2449A>T; p.I817F; 1:23083182-23083182	skin	malignant_melanoma	Substitution - Missense
c.2410A>G; p.I804V; 1:23082331-23082331	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2233G>A; p.D745N; 1:23081508-23081508	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2233G>A; p.D745N; 1:23081508-23081508	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2233G>A; p.D745N; 1:23081508-23081508	liver	carcinoma	Substitution - Missense
c.754G>A; p.E252K; 1:23053803-23053803	urinary_tract; bladder	carcinoma	Substitution - Missense
c.754G>A; p.E252K; 1:23053803-23053803	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1932A>T; p.A644A; 1:23079054-23079054	liver	carcinoma	Substitution - coding silent
c.1995A>G; p.P665P; 1:23079117-23079117	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.2409A>G; p.P803P; 1:23082330-23082330	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1597C>T; p.Q533*; 1:23072172-23072172	skin	malignant_melanoma	Substitution - Nonsense
c.2537C>T; p.A846V; 1:23083270-23083270	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.1874A>C; p.E625A; 1:23078996-23078996	liver	carcinoma	Substitution - Missense
c.1874A>C; p.E625A; 1:23078996-23078996	liver	carcinoma	Substitution - Missense
c.747G>A; p.L249L; 1:23053796-23053796	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.251A>G; p.Q84R; 1:23019847-23019847	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1189G>C; p.E397Q; 1:23068548-23068548	breast	carcinoma	Substitution - Missense
c.1501G>A; p.E501K; 1:23071312-23071312	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.676A>G; p.T226A; 1:23050485-23050485	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2031G>A; p.R677R; 1:23079153-23079153	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1266C>T; p.F422F; 1:23068625-23068625	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1021C>T; p.R341C; 1:23057514-23057514	skin	malignant_melanoma	Substitution - Missense
c.2440C>A; p.P814T; 1:23082361-23082361	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.852C>T; p.F284F; 1:23055130-23055130	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.852C>T; p.F284F; 1:23055130-23055130	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1399G>T; p.E467*; 1:23069137-23069137	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1522C>G; p.H508D; 1:23071333-23071333	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1735_1737delGAT; p.D581delD; 1:23077228-23077230	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - In frame
c.1641A>G; p.S547S; 1:23073310-23073310	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2050A>T; p.N684Y; 1:23079172-23079172	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.422G>T; p.R141I; 1:23030539-23030539	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.456C>T; p.P152P; 1:23030573-23030573	skin	malignant_melanoma	Substitution - coding silent
c.599A>G; p.Q200R; 1:23050408-23050408	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1995A>C; p.P665P; 1:23079117-23079117	breast	carcinoma	Substitution - coding silent
c.1007G>A; p.R336Q; 1:23057500-23057500	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1896C>T; p.R632R; 1:23079018-23079018	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.982G>A; p.E328K; 1:23056030-23056030	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1658T>C; p.L553P; 1:23073327-23073327	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.104C>T; p.S35F; 1:23019700-23019700	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1092delG; p.V365fs*5; 1:23059092-23059092	skin; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.812G>T; p.R271L; 1:23055090-23055090	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.775G>A; p.E259K; 1:23053824-23053824	breast	carcinoma	Substitution - Missense
c.454C>A; p.P152T; 1:23030571-23030571	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2106C>T; p.F702F; 1:23079603-23079603	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1251T>C; p.S417S; 1:23068610-23068610	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.985G>A; p.A329T; 1:23056033-23056033	pancreas	carcinoma	Substitution - Missense
c.1665G>T; p.W555C; 1:23073334-23073334	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.1931C>T; p.A644V; 1:23079053-23079053	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.943C>A; p.R315R; 1:23055991-23055991	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.577+5G>T; p.?; 1:23044491-23044491	lung	carcinoma; non_small_cell_carcinoma	Unknown
c.577+5G>T; p.?; 1:23044491-23044491	lung	carcinoma; non_small_cell_carcinoma	Unknown
c.35C>T; p.A12V; 1:23019631-23019631	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2471G>A; p.G824E; 1:23083204-23083204	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1981G>A; p.V661I; 1:23079103-23079103	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1433A>G; p.K478R; 1:23071244-23071244	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1981G>A; p.V661I; 1:23079103-23079103	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1926C>T; p.C642C; 1:23079048-23079048	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1272C>T; p.V424V; 1:23068631-23068631	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1926C>T; p.C642C; 1:23079048-23079048	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.847A>G; p.N283D; 1:23055125-23055125	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1926C>T; p.C642C; 1:23079048-23079048	central_nervous_system; brain	glioma	Substitution - coding silent
c.541G>C; p.D181H; 1:23044450-23044450	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense

The somatic mutations from COSMIC database