Entrez Gene

Basic Information
Gene ID	2048
Name	EPHB2

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.1882G>A; p.G628R; 1:22906103-22906103	pancreas	carcinoma	Substitution - Missense
c.1036C>A; p.P346T; 1:22864945-22864945	liver	carcinoma	Substitution - Missense
c.2372G>A; p.R791H; 1:22909041-22909041	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.2107G>T; p.E703*; 1:22906928-22906928	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1036C>A; p.P346T; 1:22864945-22864945	liver	carcinoma	Substitution - Missense
c.2365C>T; p.P789S; 1:22909034-22909034	skin	malignant_melanoma	Substitution - Missense
c.1647C>T; p.A549A; 1:22895527-22895527	skin	malignant_melanoma	Substitution - coding silent
c.1432C>T; p.L478F; 1:22892887-22892887	liver	carcinoma	Substitution - Missense
c.1432C>T; p.L478F; 1:22892887-22892887	liver	carcinoma	Substitution - Missense
c.1889-1G>C; p.?; 1:22906709-22906709	urinary_tract; bladder	carcinoma	Unknown
c.2409C>T; p.F803F; 1:22909078-22909078	skin	malignant_melanoma	Substitution - coding silent
c.1340G>A; p.R447H; 1:22882395-22882395	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2802C>T; p.F934F; 1:22912549-22912549	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1725G>A; p.S575S; 1:22896438-22896438	skin	malignant_melanoma	Substitution - coding silent
c.69A>G; p.L23L; 1:22781428-22781428	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2346T>G; p.S782R; 1:22908162-22908162	skin	malignant_melanoma	Substitution - Missense
c.366G>A; p.S122S; 1:22784631-22784631	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.426A>C; p.A142A; 1:22784691-22784691	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.2628T>G; p.I876M; 1:22910507-22910507	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.824G>A; p.G275E; 1:22863049-22863049	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2200A>G; p.M734V; 1:22908016-22908016	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.736G>A; p.E246K; 1:22785001-22785001	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.631C>T; p.L211L; 1:22784896-22784896	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.987G>A; p.Q329Q; 1:22864896-22864896	skin	malignant_melanoma	Substitution - coding silent
c.1290C>T; p.T430T; 1:22865199-22865199	skin	malignant_melanoma	Substitution - coding silent
c.1049C>T; p.S350F; 1:22864958-22864958	skin; upper_leg	malignant_melanoma	Substitution - Missense
c.1454C>T; p.A485V; 1:22892909-22892909	skin	malignant_melanoma	Substitution - Missense
c.1407T>A; p.Y469*; 1:22882462-22882462	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.242G>A; p.R81H; 1:22784507-22784507	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.914G>A; p.C305Y; 1:22863139-22863139	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2474G>A; p.R825Q; 1:22909143-22909143	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2474G>A; p.R825Q; 1:22909143-22909143	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1980G>A; p.T660T; 1:22906801-22906801	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.325G>A; p.E109K; 1:22784590-22784590	skin; arm	malignant_melanoma	Substitution - Missense
c.1980G>A; p.T660T; 1:22906801-22906801	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1638C>A; p.G546G; 1:22895518-22895518	thyroid	other; neoplasm	Substitution - coding silent
c.1733C>T; p.T578M; 1:22896446-22896446	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.170G>A; p.R57H; 1:22784435-22784435	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3097C>T; p.R1033W; 1:22913799-22913799	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2660C>T; p.P887L; 1:22910539-22910539	skin; shoulder	malignant_melanoma	Substitution - Missense
c.1043G>A; p.R348H; 1:22864952-22864952	pancreas	carcinoma	Substitution - Missense
c.2560G>A; p.A854T; 1:22910439-22910439	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1043G>A; p.R348H; 1:22864952-22864952	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1722C>T; p.D574D; 1:22896435-22896435	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1734G>A; p.T578T; 1:22896447-22896447	skin	malignant_melanoma	Substitution - coding silent
c.1722C>T; p.D574D; 1:22896435-22896435	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.2031C>T; p.F677F; 1:22906852-22906852	skin	malignant_melanoma	Substitution - coding silent
c.2513C>G; p.A838G; 1:22910392-22910392	urinary_tract; bladder	carcinoma	Substitution - Missense
c.917G>A; p.R306H; 1:22863142-22863142	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.568G>A; p.V190M; 1:22784833-22784833	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.591C>T; p.C197C; 1:22784856-22784856	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1796C>T; p.P599L; 1:22906017-22906017	skin	malignant_melanoma	Substitution - Missense
c.1796C>T; p.P599L; 1:22906017-22906017	skin	malignant_melanoma	Substitution - Missense
c.2446A>G; p.M816V; 1:22909115-22909115	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2832C>T; p.V944V; 1:22912579-22912579	lung	carcinoma; non_small_cell_carcinoma	Substitution - coding silent
c.2832C>T; p.V944V; 1:22912579-22912579	lung	carcinoma; non_small_cell_carcinoma	Substitution - coding silent
c.2832C>T; p.V944V; 1:22912579-22912579	skin	malignant_melanoma	Substitution - coding silent
c.318C>A; p.S106S; 1:22784583-22784583	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.232A>T; p.I78F; 1:22784497-22784497	skin	malignant_melanoma	Substitution - Missense
c.978C>T; p.S326S; 1:22864887-22864887	skin	malignant_melanoma	Substitution - coding silent
c.746T>G; p.V249G; 1:22785011-22785011	thyroid	other; neoplasm	Substitution - Missense
c.978C>T; p.S326S; 1:22864887-22864887	skin	malignant_melanoma	Substitution - coding silent
c.1994G>A; p.R665Q; 1:22906815-22906815	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.978C>T; p.S326S; 1:22864887-22864887	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.746T>G; p.V249G; 1:22785011-22785011	skin; ear	malignant_melanoma	Substitution - Missense
c.2058G>A; p.E686E; 1:22906879-22906879	skin	malignant_melanoma	Substitution - coding silent
c.1371C>T; p.S457S; 1:22882426-22882426	skin	malignant_melanoma	Substitution - coding silent
c.235C>T; p.R79W; 1:22784500-22784500	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.682G>A; p.A228T; 1:22784947-22784947	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2804C>G; p.A935G; 1:22912551-22912551	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.235C>T; p.R79W; 1:22784500-22784500	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2289G>A; p.S763S; 1:22908105-22908105	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.2289G>A; p.S763S; 1:22908105-22908105	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.2289G>A; p.S763S; 1:22908105-22908105	skin	malignant_melanoma	Substitution - coding silent
c.2289G>A; p.S763S; 1:22908105-22908105	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.980C>T; p.A327V; 1:22864889-22864889	prostate	carcinoma	Substitution - Missense
c.238C>T; p.R80C; 1:22784503-22784503	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2864G>T; p.R955L; 1:22913473-22913473	skin	malignant_melanoma	Substitution - Missense
c.3092delG; p.R1033fs*>23; 1:22913794-22913794	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2789A>G; p.Y930C; 1:22912536-22912536	meninges	meningioma	Substitution - Missense
c.2378C>A; p.T793K; 1:22909047-22909047	thyroid	other; neoplasm	Substitution - Missense
c.2164C>T; p.Q722*; 1:22907980-22907980	prostate	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1086C>T; p.C362C; 1:22864995-22864995	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2517T>G; p.I839M; 1:22910396-22910396	breast	carcinoma	Substitution - Missense
c.654G>A; p.S218S; 1:22784919-22784919	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1027G>A; p.E343K; 1:22864936-22864936	skin	malignant_melanoma	Substitution - Missense
c.1772C>T; p.P591L; 1:22905993-22905993	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2107G>A; p.E703K; 1:22906928-22906928	skin	malignant_melanoma	Substitution - Missense
c.2958C>A; p.G986G; 1:22913660-22913660	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.2107G>A; p.E703K; 1:22906928-22906928	skin	malignant_melanoma	Substitution - Missense
c.1301C>T; p.A434V; 1:22865210-22865210	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1792G>A; p.D598N; 1:22906013-22906013	skin	malignant_melanoma	Substitution - Missense
c.653C>T; p.S218L; 1:22784918-22784918	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.164C>T; p.T55M; 1:22784429-22784429	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3127G>A; p.D1043N; 1:22913829-22913829	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.164C>T; p.T55M; 1:22784429-22784429	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2060G>A; p.G687D; 1:22906881-22906881	skin	malignant_melanoma	Substitution - Missense
c.1991G>T; p.R664L; 1:22906812-22906812	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2670delC; p.A892fs*57; 1:22910549-22910549	pancreas	carcinoma; adenocarcinoma	Deletion - Frameshift
c.118C>T; p.P40S; 1:22781477-22781477	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.853G>A; p.A285T; 1:22863078-22863078	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.848A>G; p.D283G; 1:22863073-22863073	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.278C>T; p.S93L; 1:22784543-22784543	skin	malignant_melanoma	Substitution - Missense
c.3051A>G; p.G1017G; 1:22913753-22913753	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2830G>A; p.V944I; 1:22912577-22912577	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.394G>A; p.E132K; 1:22784659-22784659	skin	malignant_melanoma	Substitution - Missense
c.2414C>T; p.S805L; 1:22909083-22909083	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1306C>T; p.P436S; 1:22882361-22882361	skin; scalp	malignant_melanoma	Substitution - Missense
c.1168G>T; p.E390*; 1:22865077-22865077	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1068C>T; p.L356L; 1:22864977-22864977	breast	carcinoma	Substitution - coding silent
c.294C>A; p.S98R; 1:22784559-22784559	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1257C>T; p.P419P; 1:22865166-22865166	liver	carcinoma	Substitution - coding silent
c.780C>T; p.F260F; 1:22785045-22785045	skin	malignant_melanoma	Substitution - coding silent
c.507G>A; p.V169V; 1:22784772-22784772	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1257C>T; p.P419P; 1:22865166-22865166	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2044G>A; p.V682I; 1:22906865-22906865	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1971G>T; p.S657S; 1:22906792-22906792	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1276T>C; p.S426P; 1:22865185-22865185	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.189C>T; p.N63N; 1:22784454-22784454	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2233C>T; p.R745C; 1:22908049-22908049	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1561G>A; p.G521S; 1:22893016-22893016	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2373C>A; p.R791R; 1:22909042-22909042	pancreas	carcinoma	Substitution - coding silent
c.2191G>A; p.A731T; 1:22908007-22908007	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3010C>T; p.P1004S; 1:22913712-22913712	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.636G>A; p.S212S; 1:22784901-22784901	pancreas	NS	Substitution - coding silent
c.636G>A; p.S212S; 1:22784901-22784901	pancreas	carcinoma	Substitution - coding silent
c.793A>G; p.N265D; 1:22785058-22785058	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1177delA; p.I393fs*19; 1:22865086-22865086	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.1177delA; p.I393fs*19; 1:22865086-22865086	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.1177delA; p.I393fs*19; 1:22865086-22865086	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.1177delA; p.I393fs*19; 1:22865086-22865086	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.1177delA; p.I393fs*19; 1:22865086-22865086	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.1177delA; p.I393fs*19; 1:22865086-22865086	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.1177delA; p.I393fs*19; 1:22865086-22865086	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.1177delA; p.I393fs*19; 1:22865086-22865086	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.1246G>T; p.D416Y; 1:22865155-22865155	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.115C>T; p.P39S; 1:22781474-22781474	skin	malignant_melanoma	Substitution - Missense
c.1575C>T; p.F525F; 1:22893030-22893030	skin	malignant_melanoma	Substitution - coding silent
c.2531G>A; p.R844Q; 1:22910410-22910410	skin	malignant_melanoma	Substitution - Missense
c.753C>T; p.I251I; 1:22785018-22785018	breast	carcinoma	Substitution - coding silent
c.1126G>A; p.G376R; 1:22865035-22865035	skin	malignant_melanoma	Substitution - Missense
c.2595G>A; p.K865K; 1:22910474-22910474	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.181G>C; p.V61L; 1:22784446-22784446	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1052G>A; p.G351E; 1:22864961-22864961	skin	malignant_melanoma	Substitution - Missense
c.2353-1G>T; p.?; 1:22909021-22909021	skin	malignant_melanoma	Unknown
c.488T>C; p.V163A; 1:22784753-22784753	skin	malignant_melanoma	Substitution - Missense
c.2881G>A; p.A961T; 1:22913490-22913490	skin	malignant_melanoma	Substitution - Missense
c.491G>A; p.R164Q; 1:22784756-22784756	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.491G>A; p.R164Q; 1:22784756-22784756	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2619C>T; p.F873F; 1:22910498-22910498	skin	malignant_melanoma	Substitution - coding silent
c.517G>A; p.G173S; 1:22784782-22784782	liver	carcinoma	Substitution - Missense
c.1927C>A; p.P643T; 1:22906748-22906748	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.517G>A; p.G173S; 1:22784782-22784782	liver	carcinoma	Substitution - Missense
c.984C>A; p.P328P; 1:22864893-22864893	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1881C>T; p.I627I; 1:22906102-22906102	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1535C>T; p.T512I; 1:22892990-22892990	skin; arm	malignant_melanoma	Substitution - Missense
c.1627C>T; p.L543F; 1:22895507-22895507	breast	carcinoma	Substitution - Missense
c.1420T>C; p.Y474H; 1:22882475-22882475	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2463C>G; p.S821S; 1:22909132-22909132	kidney	other; neoplasm	Substitution - coding silent
c.1390G>A; p.G464S; 1:22882445-22882445	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.531C>T; p.A177A; 1:22784796-22784796	breast	carcinoma	Substitution - coding silent
c.1552C>T; p.R518C; 1:22893007-22893007	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1552C>T; p.R518C; 1:22893007-22893007	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Burkitt_lymphoma	Substitution - Missense
c.2675C>A; p.A892D; 1:22910554-22910554	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2562C>T; p.A854A; 1:22910441-22910441	skin	malignant_melanoma	Substitution - coding silent
c.220C>T; p.R74W; 1:22784485-22784485	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.949C>A; p.L317M; 1:22863174-22863174	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.999C>T; p.S333S; 1:22864908-22864908	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1069G>A; p.V357I; 1:22864978-22864978	breast	carcinoma	Substitution - Missense
c.1069G>A; p.V357I; 1:22864978-22864978	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.952G>A; p.D318N; 1:22863177-22863177	skin; shoulder	malignant_melanoma	Substitution - Missense
c.1724C>T; p.S575L; 1:22896437-22896437	oesophagus	carcinoma	Substitution - Missense
c.1402G>T; p.D468Y; 1:22882457-22882457	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1491C>A; p.G497G; 1:22892946-22892946	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3150C>T; p.D1050D; 1:22913852-22913852	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1765+2T>C; p.?; 1:22896480-22896480	large_intestine; caecum	carcinoma; adenocarcinoma	Unknown
c.509C>T; p.S170F; 1:22784774-22784774	skin	malignant_melanoma	Substitution - Missense
c.509C>T; p.S170F; 1:22784774-22784774	skin	malignant_melanoma	Substitution - Missense
c.207G>A; p.Q69Q; 1:22784472-22784472	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.306C>T; p.S102S; 1:22784571-22784571	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2234G>C; p.R745P; 1:22908050-22908050	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1122C>T; p.R374R; 1:22865031-22865031	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2007C>T; p.S669S; 1:22906828-22906828	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2007C>T; p.S669S; 1:22906828-22906828	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2007C>T; p.S669S; 1:22906828-22906828	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2007C>T; p.S669S; 1:22906828-22906828	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.466G>A; p.V156I; 1:22784731-22784731	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2653C>T; p.R885C; 1:22910532-22910532	skin	malignant_melanoma	Substitution - Missense
c.2599C>T; p.R867C; 1:22910478-22910478	skin	malignant_melanoma	Substitution - Missense
c.2298G>A; p.G766G; 1:22908114-22908114	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2581G>A; p.D861N; 1:22910460-22910460	skin	malignant_melanoma	Substitution - Missense
c.2652C>T; p.I884I; 1:22910531-22910531	skin	malignant_melanoma	Substitution - coding silent
c.466G>A; p.V156I; 1:22784731-22784731	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.450G>A; p.V150V; 1:22784715-22784715	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.329C>A; p.T110N; 1:22784594-22784594	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2238C>T; p.D746D; 1:22908054-22908054	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1365G>A; p.S455S; 1:22882420-22882420	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1702C>T; p.R568W; 1:22896415-22896415	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1830G>A; p.R610R; 1:22906051-22906051	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1702C>T; p.R568W; 1:22896415-22896415	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1549G>A; p.G517R; 1:22893004-22893004	breast	carcinoma	Substitution - Missense
c.643G>A; p.E215K; 1:22784908-22784908	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1702C>T; p.R568W; 1:22896415-22896415	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1201C>A; p.H401N; 1:22865110-22865110	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.221G>A; p.R74Q; 1:22784486-22784486	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.534C>T; p.F178F; 1:22784799-22784799	skin	malignant_melanoma	Substitution - coding silent
c.221G>A; p.R74Q; 1:22784486-22784486	skin	malignant_melanoma	Substitution - Missense
c.1501G>A; p.G501S; 1:22892956-22892956	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1378G>A; p.D460N; 1:22882433-22882433	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1041C>T; p.P347P; 1:22864950-22864950	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.909T>C; p.C303C; 1:22863134-22863134	skin	malignant_melanoma	Substitution - coding silent
c.2098G>A; p.E700K; 1:22906919-22906919	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2680G>A; p.A894T; 1:22910559-22910559	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2454G>A; p.E818E; 1:22909123-22909123	liver	carcinoma	Substitution - coding silent
c.2364C>T; p.I788I; 1:22909033-22909033	skin	malignant_melanoma	Substitution - coding silent
c.3048C>T; p.D1016D; 1:22913750-22913750	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.411G>A; p.K137K; 1:22784676-22784676	skin	malignant_melanoma	Substitution - coding silent
c.548G>A; p.G183D; 1:22784813-22784813	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1819G>A; p.E607K; 1:22906040-22906040	skin; scalp	malignant_melanoma	Substitution - Missense
c.1819G>A; p.E607K; 1:22906040-22906040	skin	malignant_melanoma	Substitution - Missense
c.1819G>A; p.E607K; 1:22906040-22906040	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1842G>A; p.K614K; 1:22906063-22906063	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.699G>A; p.V233V; 1:22784964-22784964	NS	malignant_melanoma	Substitution - coding silent
c.699G>A; p.V233V; 1:22784964-22784964	NS	malignant_melanoma	Substitution - coding silent
c.2097C>T; p.T699T; 1:22906918-22906918	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1031G>T; p.W344L; 1:22864940-22864940	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1923G>A; p.K641K; 1:22906744-22906744	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2860C>A; p.L954I; 1:22913469-22913469	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1818C>T; p.N606N; 1:22906039-22906039	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2259C>T; p.L753L; 1:22908075-22908075	skin	malignant_melanoma	Substitution - coding silent
c.65C>T; p.T22M; 1:22781424-22781424	pancreas	carcinoma	Substitution - Missense
c.91G>A; p.A31T; 1:22781450-22781450	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2724G>A; p.T908T; 1:22912471-22912471	skin	malignant_melanoma	Substitution - coding silent
c.1339C>T; p.R447C; 1:22882394-22882394	skin	malignant_melanoma	Substitution - Missense
c.729G>A; p.G243G; 1:22784994-22784994	skin	malignant_melanoma	Substitution - coding silent
c.65C>T; p.T22M; 1:22781424-22781424	kidney	other; neoplasm	Substitution - Missense
c.128G>T; p.W43L; 1:22784393-22784393	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1263G>T; p.S421S; 1:22865172-22865172	breast	carcinoma	Substitution - coding silent
c.2690C>T; p.S897F; 1:22910569-22910569	skin	malignant_melanoma	Substitution - Missense
c.579C>G; p.F193L; 1:22784844-22784844	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2008G>A; p.E670K; 1:22906829-22906829	skin	malignant_melanoma	Substitution - Missense
c.94G>A; p.E32K; 1:22781453-22781453	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1828C>T; p.R610W; 1:22906049-22906049	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1175G>A; p.R392H; 1:22865084-22865084	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1175G>A; p.R392H; 1:22865084-22865084	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1175G>A; p.R392H; 1:22865084-22865084	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1175G>A; p.R392H; 1:22865084-22865084	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.2248C>T; p.R750C; 1:22908064-22908064	skin	malignant_melanoma	Substitution - Missense
c.2126C>T; p.S709F; 1:22906947-22906947	skin	malignant_melanoma	Substitution - Missense
c.1791C>T; p.I597I; 1:22906012-22906012	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3051delA; p.K1020fs*>36; 1:22913753-22913753	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2209C>T; p.L737L; 1:22908025-22908025	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3051delA; p.K1020fs*>36; 1:22913753-22913753	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2232C>T; p.H744H; 1:22908048-22908048	skin	malignant_melanoma	Substitution - coding silent
c.1345G>A; p.V449M; 1:22882400-22882400	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2495A>G; p.N832S; 1:22909164-22909164	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.614C>T; p.A205V; 1:22784879-22784879	skin; back	malignant_melanoma	Substitution - Missense
c.1277C>G; p.S426C; 1:22865186-22865186	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1071C>G; p.V357V; 1:22864980-22864980	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2665A>G; p.S889G; 1:22910544-22910544	breast	carcinoma	Substitution - Missense
c.2635A>G; p.T879A; 1:22910514-22910514	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.606G>T; p.Q202H; 1:22784871-22784871	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2422G>A; p.D808N; 1:22909091-22909091	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2088G>A; p.M696I; 1:22906909-22906909	skin	malignant_melanoma	Substitution - Missense
c.2928G>A; p.A976A; 1:22913537-22913537	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1106G>A; p.R369Q; 1:22865015-22865015	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Burkitt_lymphoma	Substitution - Missense
c.2769G>T; p.E923D; 1:22912516-22912516	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2319C>T; p.D773D; 1:22908135-22908135	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1482C>T; p.T494T; 1:22892937-22892937	skin	malignant_melanoma	Substitution - coding silent
c.1044C>T; p.R348R; 1:22864953-22864953	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.262G>A; p.V88M; 1:22784527-22784527	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.262G>A; p.V88M; 1:22784527-22784527	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.261C>T; p.H87H; 1:22784526-22784526	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - coding silent
c.2620G>A; p.G874S; 1:22910499-22910499	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1843G>A; p.E615K; 1:22906064-22906064	skin; knee	malignant_melanoma	Substitution - Missense
c.261C>T; p.H87H; 1:22784526-22784526	breast	carcinoma	Substitution - coding silent
c.1843G>A; p.E615K; 1:22906064-22906064	skin; upper_leg	malignant_melanoma	Substitution - Missense
c.1843G>A; p.E615K; 1:22906064-22906064	skin	malignant_melanoma	Substitution - Missense
c.1843G>A; p.E615K; 1:22906064-22906064	skin	malignant_melanoma	Substitution - Missense
c.1843G>A; p.E615K; 1:22906064-22906064	skin	malignant_melanoma	Substitution - Missense
c.2620G>A; p.G874S; 1:22910499-22910499	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2682G>A; p.A894A; 1:22910561-22910561	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.153G>T; p.E51D; 1:22784418-22784418	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2818A>C; p.T940P; 1:22912565-22912565	urinary_tract; bladder	carcinoma	Substitution - Missense
c.603C>T; p.I201I; 1:22784868-22784868	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.1246G>C; p.D416H; 1:22865155-22865155	prostate	carcinoma	Substitution - Missense
c.2905A>T; p.N969Y; 1:22913514-22913514	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense

The somatic mutations from COSMIC database