| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |||
|---|---|---|---|
Gene ID | 200504 | ||
Name | GKN2 | ||
The somatic mutations from COSMIC database | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.232C>T; p.R78*; 2:68947230-68947230 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Nonsense |
c.338G>A; p.S113N; 2:68946438-68946438 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm; acute_myeloid_leukaemia | Substitution - Missense |
c.338G>A; p.S113N; 2:68946438-68946438 |
thyroid | other; neoplasm | Substitution - Missense |
c.338G>A; p.S113N; 2:68946438-68946438 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm; acute_myeloid_leukaemia | Substitution - Missense |
c.406G>T; p.G136W; 2:68946370-68946370 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.279delT; p.L94fs*1; 2:68947183-68947183 |
stomach | carcinoma; intestinal_adenocarcinoma | Deletion - Frameshift |
c.155A>C; p.N52T; 2:68950175-68950175 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.155A>C; p.N52T; 2:68950175-68950175 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.218C>A; p.S73Y; 2:68947244-68947244 |
breast | carcinoma; ductal_carcinoma | Substitution - Missense |
c.140A>G; p.N47S; 2:68950190-68950190 |
liver | carcinoma | Substitution - Missense |
c.29T>C; p.V10A; 2:68950739-68950739 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.385G>A; p.D129N; 2:68946391-68946391 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.345C>T; p.Y115Y; 2:68946431-68946431 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.277_278CC>TT; p.P93F; 2:68947184-68947185 |
skin; mucosal | malignant_melanoma | Substitution - Missense |
c.206G>A; p.G69D; 2:68947256-68947256 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.439C>T; p.P147S; 2:68946337-68946337 |
skin | malignant_melanoma | Substitution - Missense |
c.538G>A; p.A180T; 2:68945385-68945385 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.317C>T; p.A106V; 2:68946459-68946459 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.317C>T; p.A106V; 2:68946459-68946459 |
kidney | other; neoplasm | Substitution - Missense |
c.280C>T; p.L94L; 2:68947182-68947182 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.280C>T; p.L94L; 2:68947182-68947182 |
skin | malignant_melanoma | Substitution - coding silent |
c.149T>G; p.I50S; 2:68950181-68950181 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.552T>C; p.V184V; 2:68945371-68945371 |
skin | malignant_melanoma | Substitution - coding silent |
c.445T>C; p.Y149H; 2:68946331-68946331 |
liver | carcinoma | Substitution - Missense |
c.445T>C; p.Y149H; 2:68946331-68946331 |
liver | carcinoma; hepatocellular_carcinoma | Substitution - Missense |
c.449A>C; p.K150T; 2:68946327-68946327 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.263A>G; p.H88R; 2:68947199-68947199 |
oesophagus | carcinoma; adenocarcinoma | Substitution - Missense |
c.230C>T; p.S77F; 2:68947232-68947232 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.350G>A; p.W117*; 2:68946426-68946426 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Nonsense |
c.139_140delAA; p.N47fs*5; 2:68950190-68950191 |
large_intestine | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.139_140delAA; p.N47fs*5; 2:68950190-68950191 |
large_intestine | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.421A>C; p.K141Q; 2:68946355-68946355 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.28G>A; p.V10M; 2:68950740-68950740 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.472C>G; p.H158D; 2:68946304-68946304 |
lung | carcinoma; small_cell_carcinoma | Substitution - Missense |
c.438C>T; p.I146I; 2:68946338-68946338 |
skin | malignant_melanoma | Substitution - coding silent |
c.387C>A; p.D129E; 2:68946389-68946389 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.391G>A; p.D131N; 2:68946385-68946385 |
autonomic_ganglia | neuroblastoma | Substitution - Missense |
c.358T>G; p.Y120D; 2:68946418-68946418 |
stomach | carcinoma; intestinal_adenocarcinoma | Substitution - Missense |
c.236G>A; p.R79K; 2:68947226-68947226 |
skin | malignant_melanoma | Substitution - Missense |
c.22C>A; p.L8M; 2:68950746-68950746 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.305A>G; p.Y102C; 2:68947157-68947157 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.480C>T; p.V160V; 2:68945443-68945443 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.179C>G; p.S60C; 2:68950151-68950151 |
oesophagus; lower_third | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.463G>A; p.E155K; 2:68946313-68946313 |
skin | malignant_melanoma | Substitution - Missense |
c.374C>A; p.S125Y; 2:68946402-68946402 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.378G>C; p.L126L; 2:68946398-68946398 |
prostate | carcinoma; adenocarcinoma | Substitution - coding silent |
c.451G>T; p.G151W; 2:68946325-68946325 |
skin | malignant_melanoma | Substitution - Missense |
c.97G>T; p.G33C; 2:68950233-68950233 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.259G>C; p.D87H; 2:68947203-68947203 |
breast | carcinoma | Substitution - Missense |
c.435T>C; p.H145H; 2:68946341-68946341 |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | Substitution - coding silent |
c.435T>C; p.H145H; 2:68946341-68946341 |
lung | carcinoma; adenocarcinoma | Substitution - coding silent |
c.367C>A; p.L123M; 2:68946409-68946409 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.385G>T; p.D129Y; 2:68946391-68946391 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.249C>G; p.I83M; 2:68947213-68947213 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.249C>G; p.I83M; 2:68947213-68947213 |
urinary_tract; bladder | carcinoma; transitional_cell_carcinoma | Substitution - Missense |
c.249C>G; p.I83M; 2:68947213-68947213 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.122C>T; p.T41I; 2:68950208-68950208 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.205-1G>A; p.?; 2:68947258-68947258 |
stomach | carcinoma; adenocarcinoma | Unknown |