Entrez Gene

Basic Information
Gene ID	196
Name	AHR

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.1843G>T; p.E615*; 7:17339668-17339668	oesophagus	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1978G>A; p.V660M; 7:17339803-17339803	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2449A>C; p.N817H; 7:17342966-17342966	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.513G>A; p.Q171Q; 7:17330014-17330014	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.132T>C; p.N44N; 7:17310002-17310002	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.394G>A; p.D132N; 7:17327792-17327792	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.394G>A; p.D132N; 7:17327792-17327792	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.143A>G; p.D48G; 7:17310013-17310013	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2365A>C; p.N789H; 7:17340190-17340190	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1151G>A; p.R384K; 7:17335777-17335777	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.861T>C; p.F287F; 7:17334067-17334067	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.318C>T; p.F106F; 7:17322565-17322565	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.318C>T; p.F106F; 7:17322565-17322565	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.110A>C; p.K37T; 7:17309980-17309980	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1147C>T; p.Q383*; 7:17335773-17335773	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.422C>A; p.T141N; 7:17327820-17327820	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1748C>T; p.T583M; 7:17339573-17339573	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.422C>A; p.T141N; 7:17327820-17327820	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1193G>A; p.R398Q; 7:17339018-17339018	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1384C>T; p.Q462*; 7:17339209-17339209	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1193G>A; p.R398Q; 7:17339018-17339018	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1193G>A; p.R398Q; 7:17339018-17339018	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1193G>A; p.R398Q; 7:17339018-17339018	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.951G>A; p.T317T; 7:17334929-17334929	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.1334C>T; p.T445I; 7:17339159-17339159	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.80C>T; p.P27L; 7:17309950-17309950	skin	malignant_melanoma	Substitution - Missense
c.2099T>G; p.F700C; 7:17339924-17339924	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2026A>G; p.T676A; 7:17339851-17339851	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1516G>A; p.D506N; 7:17339341-17339341	breast	carcinoma	Substitution - Missense
c.701T>A; p.F234Y; 7:17330882-17330882	thyroid	carcinoma	Substitution - Missense
c.468G>C; p.Q156H; 7:17329969-17329969	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.779C>T; p.P260L; 7:17333985-17333985	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.271C>T; p.P91S; 7:17322518-17322518	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.216C>T; p.L72L; 7:17310086-17310086	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1333A>G; p.T445A; 7:17339158-17339158	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.730A>T; p.K244*; 7:17333936-17333936	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Nonsense
c.10A>G; p.S4G; 7:17299274-17299274	pancreas	carcinoma	Substitution - Missense
c.2464C>T; p.Q822*; 7:17342981-17342981	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.2463T>C; p.T821T; 7:17342980-17342980	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2463T>C; p.T821T; 7:17342980-17342980	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2463T>C; p.T821T; 7:17342980-17342980	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.194A>G; p.D65G; 7:17310064-17310064	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1225G>A; p.G409R; 7:17339050-17339050	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2463T>C; p.T821T; 7:17342980-17342980	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.119G>C; p.R40T; 7:17309989-17309989	breast	carcinoma	Substitution - Missense
c.2190C>T; p.P730P; 7:17340015-17340015	skin	malignant_melanoma	Substitution - coding silent
c.1489C>G; p.Q497E; 7:17339314-17339314	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.914G>A; p.R305K; 7:17334892-17334892	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.914G>A; p.R305K; 7:17334892-17334892	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1710T>G; p.V570V; 7:17339535-17339535	ovary	other; neoplasm	Substitution - coding silent
c.587_588insC; p.Q198fs*7; 7:17330768-17330769	oesophagus; lower_third	carcinoma; adenocarcinoma	Insertion - Frameshift
c.2526G>T; p.L842F; 7:17343043-17343043	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.985G>A; p.D329N; 7:17334963-17334963	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1708G>A; p.V570I; 7:17339533-17339533	thyroid	other; neoplasm	Substitution - Missense
c.595A>C; p.T199P; 7:17330776-17330776	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.959C>G; p.S320*; 7:17334937-17334937	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.220G>A; p.V74I; 7:17310090-17310090	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.727T>C; p.L243L; 7:17333933-17333933	skin	malignant_melanoma	Substitution - coding silent
c.2047C>G; p.Q683E; 7:17339872-17339872	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1690A>T; p.N564Y; 7:17339515-17339515	central_nervous_system; brain	glioma	Substitution - Missense
c.1452C>G; p.N484K; 7:17339277-17339277	liver	carcinoma	Substitution - Missense
c.1335T>G; p.T445T; 7:17339160-17339160	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.275C>A; p.T92N; 7:17322522-17322522	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1668G>T; p.M556I; 7:17339493-17339493	pancreas	NS	Substitution - Missense
c.1167G>T; p.E389D; 7:17338992-17338992	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1200G>A; p.T400T; 7:17339025-17339025	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1102C>T; p.R368C; 7:17335728-17335728	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1505C>T; p.P502L; 7:17339330-17339330	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1310G>T; p.G437V; 7:17339135-17339135	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2490_2492delTCA; p.H832delH; 7:17343007-17343009	lung	carcinoma; adenocarcinoma	Deletion - In frame
c.1102C>T; p.R368C; 7:17335728-17335728	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1473T>A; p.N491K; 7:17339298-17339298	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1352_1353delTC; p.L451fs*3; 7:17339177-17339178	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.1352_1353delTC; p.L451fs*3; 7:17339177-17339178	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.1462G>A; p.E488K; 7:17339287-17339287	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1600A>T; p.S534C; 7:17339425-17339425	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.1462G>A; p.E488K; 7:17339287-17339287	kidney	other; neoplasm	Substitution - Missense
c.989T>C; p.M330T; 7:17334967-17334967	soft_tissue; blood_vessel	angiosarcoma	Substitution - Missense
c.2387A>C; p.Q796P; 7:17340212-17340212	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.817C>A; p.Q273K; 7:17334023-17334023	urinary_tract; bladder	carcinoma	Substitution - Missense
c.142G>A; p.D48N; 7:17310012-17310012	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2461A>T; p.T821S; 7:17342978-17342978	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.574+4A>C; p.?; 7:17330079-17330079	liver	carcinoma	Unknown
c.574+4A>C; p.?; 7:17330079-17330079	liver	carcinoma	Unknown
c.2081_2082insTAG; p.M694>IR; 7:17339906-17339907	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Complex - insertion inframe
c.1395G>A; p.E465E; 7:17339220-17339220	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2409G>T; p.Q803H; 7:17342926-17342926	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1395G>A; p.E465E; 7:17339220-17339220	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.1015C>A; p.R339R; 7:17334993-17334993	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.2198C>T; p.S733F; 7:17340023-17340023	skin	malignant_melanoma	Substitution - Missense
c.145C>T; p.R49C; 7:17310015-17310015	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.360G>T; p.Q120H; 7:17322607-17322607	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2466G>C; p.Q822H; 7:17342983-17342983	urinary_tract; bladder	carcinoma	Substitution - Missense
c.314A>C; p.N105T; 7:17322561-17322561	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2292T>G; p.C764W; 7:17340117-17340117	skin	malignant_melanoma	Substitution - Missense
c.1520C>T; p.T507I; 7:17339345-17339345	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1939G>A; p.V647I; 7:17339764-17339764	skin	malignant_melanoma	Substitution - Missense
c.2209G>T; p.D737Y; 7:17340034-17340034	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.514C>T; p.R172C; 7:17330015-17330015	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2078C>A; p.S693Y; 7:17339903-17339903	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2222G>T; p.C741F; 7:17340047-17340047	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2414G>A; p.G805E; 7:17342931-17342931	skin	malignant_melanoma	Substitution - Missense
c.1276C>T; p.P426S; 7:17339101-17339101	skin	malignant_melanoma	Substitution - Missense
c.1462G>T; p.E488*; 7:17339287-17339287	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.1734G>A; p.T578T; 7:17339559-17339559	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1645G>C; p.D549H; 7:17339470-17339470	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2526delG; p.T843fs*>6; 7:17343043-17343043	haematopoietic_and_lymphoid_tissue; abdomen	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.842G>T; p.R281L; 7:17334048-17334048	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1055G>A; p.R352Q; 7:17335681-17335681	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.750A>G; p.K250K; 7:17333956-17333956	liver	carcinoma	Substitution - coding silent
c.2518C>T; p.P840S; 7:17343035-17343035	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.787T>C; p.L263L; 7:17333993-17333993	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.928T>C; p.Y310H; 7:17334906-17334906	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2461A>G; p.T821A; 7:17342978-17342978	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2461A>G; p.T821A; 7:17342978-17342978	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.306A>T; p.R102S; 7:17322553-17322553	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1379T>G; p.M460R; 7:17339204-17339204	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.377T>C; p.V126A; 7:17327775-17327775	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1905G>A; p.Q635Q; 7:17339730-17339730	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1514A>G; p.N505S; 7:17339339-17339339	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1991G>T; p.C664F; 7:17339816-17339816	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1413T>C; p.P471P; 7:17339238-17339238	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.940G>C; p.E314Q; 7:17334918-17334918	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2540T>A; p.F847Y; 7:17343057-17343057	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.149T>C; p.L50S; 7:17310019-17310019	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.219C>T; p.S73S; 7:17310089-17310089	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.219C>T; p.S73S; 7:17310089-17310089	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2166G>A; p.G722G; 7:17339991-17339991	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1165G>A; p.E389K; 7:17338990-17338990	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.734A>G; p.Y245C; 7:17333940-17333940	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1705G>A; p.E569K; 7:17339530-17339530	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.128T>C; p.L43P; 7:17309998-17309998	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2528C>A; p.T843K; 7:17343045-17343045	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1384C>A; p.Q462K; 7:17339209-17339209	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.2105C>A; p.S702Y; 7:17339930-17339930	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.409T>C; p.Y137H; 7:17327807-17327807	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1468A>G; p.M490V; 7:17339293-17339293	thyroid	other; neoplasm	Substitution - Missense
c.1176A>C; p.T392T; 7:17339001-17339001	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1149G>C; p.Q383H; 7:17335775-17335775	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1149G>C; p.Q383H; 7:17335775-17335775	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1042A>G; p.M348V; 7:17335668-17335668	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1149G>C; p.Q383H; 7:17335775-17335775	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1418C>G; p.S473*; 7:17339243-17339243	NS	NS	Substitution - Nonsense
c.657C>T; p.C219C; 7:17330838-17330838	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1511G>A; p.G504E; 7:17339336-17339336	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.667C>G; p.R223G; 7:17330848-17330848	skin	malignant_melanoma	Substitution - Missense
c.1427C>G; p.S476*; 7:17339252-17339252	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.866C>T; p.T289I; 7:17334072-17334072	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1936C>T; p.Q646*; 7:17339761-17339761	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1738G>T; p.E580*; 7:17339563-17339563	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2117C>T; p.P706L; 7:17339942-17339942	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2307G>T; p.V769V; 7:17340132-17340132	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.417T>C; p.S139S; 7:17327815-17327815	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1790C>G; p.S597*; 7:17339615-17339615	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.1199C>T; p.T400M; 7:17339024-17339024	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1790C>G; p.S597*; 7:17339615-17339615	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Nonsense
c.361G>A; p.A121T; 7:17327759-17327759	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1015C>T; p.R339*; 7:17334993-17334993	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1015C>T; p.R339*; 7:17334993-17334993	large_intestine; colon	carcinoma	Substitution - Nonsense
c.1015C>T; p.R339*; 7:17334993-17334993	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.850A>C; p.N284H; 7:17334056-17334056	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2184A>G; p.P728P; 7:17340009-17340009	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1160C>T; p.T387I; 7:17335786-17335786	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2369C>T; p.P790L; 7:17340194-17340194	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2499G>A; p.P833P; 7:17343016-17343016	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2499G>A; p.P833P; 7:17343016-17343016	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2265G>C; p.Q755H; 7:17340090-17340090	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2388G>T; p.Q796H; 7:17340213-17340213	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2310G>A; p.S770S; 7:17340135-17340135	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent

The somatic mutations from COSMIC database