Entrez Gene

Basic Information
Gene ID	1746
Name	DLX2

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.579G>T; p.Q193H; 2:172101468-172101468	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.970G>A; p.A324T; 2:172100560-172100560	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.707C>A; p.S236*; 2:172100823-172100823	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.645G>C; p.E215D; 2:172100885-172100885	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.714G>T; p.P238P; 2:172100816-172100816	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.802A>C; p.S268R; 2:172100728-172100728	skin	malignant_melanoma	Substitution - Missense
c.260T>A; p.M87K; 2:172102279-172102279	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.676G>A; p.A226T; 2:172100854-172100854	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.138_139insAGC; p.S46_L47insS; 2:172102400-172102401	large_intestine; rectum	carcinoma; adenocarcinoma	Insertion - In frame
c.41C>T; p.S14L; 2:172102498-172102498	breast	carcinoma	Substitution - Missense
c.138_139insAGC; p.S46_L47insS; 2:172102400-172102401	large_intestine; rectum	carcinoma; adenocarcinoma	Insertion - In frame
c.400+2T>A; p.?; 2:172102137-172102137	large_intestine; caecum	carcinoma; adenocarcinoma	Unknown
c.400+2T>C; p.?; 2:172102137-172102137	ovary	carcinoma; serous_carcinoma	Unknown
c.400+2T>C; p.?; 2:172102137-172102137	large_intestine; rectum	carcinoma; adenocarcinoma	Unknown
c.713C>T; p.P238L; 2:172100817-172100817	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.505C>T; p.R169W; 2:172101542-172101542	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.180C>A; p.T60T; 2:172102359-172102359	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.893C>T; p.P298L; 2:172100637-172100637	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.35T>C; p.M12T; 2:172102504-172102504	pancreas	carcinoma	Substitution - Missense
c.978G>A; p.T326T; 2:172100552-172100552	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.252C>T; p.Y84Y; 2:172102287-172102287	liver	carcinoma	Substitution - coding silent
c.252C>T; p.Y84Y; 2:172102287-172102287	liver	carcinoma	Substitution - coding silent
c.663C>A; p.H221Q; 2:172100867-172100867	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.559G>T; p.A187S; 2:172101488-172101488	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.132delC; p.S44fs*101; 2:172102407-172102407	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.339C>A; p.T113T; 2:172102200-172102200	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.200A>G; p.Y67C; 2:172102339-172102339	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.473T>G; p.I158S; 2:172101574-172101574	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.654G>A; p.S218S; 2:172100876-172100876	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.519G>A; p.K173K; 2:172101528-172101528	skin	malignant_melanoma	Substitution - coding silent
c.20G>A; p.S7N; 2:172102519-172102519	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.439G>T; p.G147W; 2:172101608-172101608	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.467G>A; p.R156H; 2:172101580-172101580	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.513C>T; p.F171F; 2:172101534-172101534	skin	malignant_melanoma	Substitution - coding silent
c.439G>A; p.G147R; 2:172101608-172101608	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.581C>A; p.T194N; 2:172101466-172101466	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.237C>G; p.G79G; 2:172102302-172102302	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.948C>T; p.G316G; 2:172100582-172100582	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.207C>A; p.N69K; 2:172102332-172102332	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.610C>T; p.R204W; 2:172100920-172100920	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.746T>A; p.M249K; 2:172100784-172100784	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.392A>G; p.N131S; 2:172102147-172102147	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.437A>G; p.N146S; 2:172101610-172101610	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.358G>A; p.A120T; 2:172102181-172102181	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.930C>G; p.H310Q; 2:172100600-172100600	urinary_tract; bladder	carcinoma	Substitution - Missense
c.290T>C; p.L97P; 2:172102249-172102249	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.406G>A; p.E136K; 2:172101641-172101641	skin	malignant_melanoma	Substitution - Missense
c.525A>G; p.Q175Q; 2:172101522-172101522	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.525A>G; p.Q175Q; 2:172101522-172101522	urinary_tract; bladder	carcinoma	Substitution - coding silent

The somatic mutations from COSMIC database